Publikationen
2011
Ghani S; Riemke P; Schoenheit J; Lenze D; Stumm J; Hoogenkamp M; Lagendijk A; Heinz S; Bonifer C; Bakkers J; Abdelilah-Seyfried S; Hummel M; Rosenbauer F
Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression
Blood 118 (8): 2275-2284 (2011-08-25)
Leddin M; Perrod C; Hoogenkamp M; Ghani S; Assi S; Heinz S; Wilson NK; Follows G; Schoenheit J; Vockentanz L; Mosamam A; Chen W; Tenen DG; Westhead DR; Goettgens B; Bonifer C; Rosenbauer F
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells
Blood 117 (10): 2827-2838 (2011-03-10)
2010
Werth M; Walentin K; Aue A; Schoenheit J; Wuebken A; Pode-Shakked N; Vilianovitch L; Erdmann B; Dekel B; Bader M; Barasch J; Rosenbauer F; Luft FC; Schmidt-Ott KM
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex
Development 137 (22): 3835-3845 (2010-11)
2009
Broeske AM; Vockentanz L; Kharazi S; Huska MR; Mancini E; Scheller M; Kuhl C; Enns A; Prinz M; Jaenisch R; Nerlov C; Leutz A; Andrade-Navarro MA; Jacobsen SE; Rosenbauer F
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
Nature Genetics 41 (11): 1207-1215 (2009-11)
2008
Ebralidze AK; Guibal FC; Steidl U; Zhang P; Lee S; Bartholdy B; Jorda MA; Petkova V; Rosenbauer F; Huang G; Dayaram T; Klupp J; O'Brien KB; Will B; Hoogenkamp M; Borden KL; Bonifer C; Tenen DG
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element
Genes & Development 22 (15): 2085-2092 (2008-08-01)
2007
Steidl U; Steidl C; Ebralidze A; Chapuy B; Han HJ; Will B; Rosenbauer F; Becker A; Wagner K; Koschmieder S; Kobayashi S; Costa DB; Schulz T; OBrien KB; Verhaak RG; Delwel R; Haase D; Truemper L; Krauter J; Kohwi-Shigematsu T; Griesinger F; Tenen DG
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia
Journal of Clinical Investigation 117 (9): 2611-2620 (2007-09)
Feinberg MW; Wara AK; Cao Z; Lebedeva MA; Rosenbauer F; Iwasaki H; Hirai H; Katz JP; Haspel R; Gray S; Akashi K; Segre J; Kaestner KH; Tenen DG; Jain MK
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation
EMBO Journal 26 (18): 4138-48 (2007-09-19)
Rosenbauer F; Tenen DG
Transcription factors in myeloid development: balancing differentiation with transformation
Nature Reviews Immunology 7 (2): 105-117 (2007-02)
2006
Rosenbauer F; Owens BM; Yu L; Tumang JR; Steidl U; Kutok JL; Clayton LK; Wagner K; Scheller M; Iwasaki H; Liu C; Hackanson B; Akashi K; Leutz A; Rothstein TL; Plass C; Tenen DG
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1
Nature Genetics 38 (1): 27-37 (2006-01)
Scheller M; Huelsken J; Rosenbauer F; Taketo MM; Birchmeier W; Tenen DG; Leutz A
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation
Nature Immunology 7 (10): 1037-1047 (2006-10)
Steidl U; Rosenbauer F; Verhaak RG; Gu X; Ebralidze A; Otu HH; Klippel S; Steidl C; Bruns I; Costa DB; Wagner K; Aivado M; Kobbe G; Valk PJ; Passegue E; Libermann TA; Delwel R; Tenen DG
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells
Nature Genetics 38: 1269-1277 (2006-10-15)
Wagner K; Zhang P; Rosenbauer F; Drescher B; Kobayashi S; Radomska HS; Kutok JL; Gilliland DG; Krauter J; Tenen DG
Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy
Proceedings of the National Academy of Sciences of the United States of America 103: 6338-6343 (2006-04-18)
2005
Okuno Y; Huang G; Rosenbauer F; Evans EK; Radomska HS; Iwasaki H; Akashi K; Moreau-Gachelin F; Li Y; Zhang P; Goettgens B; Tenen DG
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element
Molecular and Cellular Biology 25: 2832-2845 (2005-04-01)
Rosenbauer F; Koschmieder S; Steidl U; Tenen DG
Effect of transcription-factor concentrations on leukemic stem cells
Blood 106: 1519-1524 (2005-09-01)
2004
Rosenbauer F; Wagner K; Zhang P; Knobeloch KP; Iwama A; Tenen DG
pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1
Blood 103: 4294-4301 (2004-06-01)
Rosenbauer F; Wagner K; Kutok JL; Iwasaki H; Le Beau MM; Okuno Y; Akashi K; Fiering S; Tenen DG
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1
Nature Genetics 36: 624-630 (2004-06-01)