Claus Scheidereit
Max-Delbrück-Center for Molecular Medicine (MDC)
Robert-Rössle-Str. 10
13125 Berlin, Germany
Phone: +49 30 9406 3816
Fax: +49 30 9406 3866
scheidereit [at] mdc-berlin.de
http://www.mdc-berlin.de/signaltransduction/
Objectives & Background
Research interest – Transcription Regulation, Signal Transduction Pathways, Molecular Mechanisms in Oncogenesis, Immunity, and Inflammation
Education & Professional Experience
Full Professor | FU-Berlin
2004 Professor of Biochemistry and Molecular Genetics
Group Leader | MDC, Berlin
1994 – present, Research Group Leader, Head of Laboratory
Affiliate Professor | FU-Berlin
1992 – 2004
Habilitation | FU-Berlin
1992 Molecular Biology
Group Leader | MPI, Berlin
1989 – 2004
Postdoctoral Fellow | Rockefeller University, New York
1988 DAAD Fellowship, 1986 – 1987 DFG Fellowship
Research Assistant | Philipps University, Marburg
1984 – 1985
Doctoral Fellow | Philipps University, Marburg
1984 PhD
Graduate training | Philipps University, Marburg
1975 – 1982, 1982 diploma in chemistry
Publications
5 selected (2003-2008)
Hinz, M., Broemer, M., Arslan, S.C., Otto, A., Mueller, E.C., Dettmer, R., and Scheidereit, C. (2007) Signal-responsiveness of Ikappa B kinases is determined by Cdc37-assisted transient interaction with Hsp90. Journal of Biological Chemistry, 282, 32311-32319.
Oeckinghaus, A., Wegener, E., Welteke, V., Ferch, U., Arslan, S.C., Ruland, J., Scheidereit, C., and Krappmann, D. (2007) Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation. EMBO Journal, 26, 4634-4645.
Hinz, M., and Scheidereit, C. (2007) Striking back at the activator: how IkappaB kinase terminates antigen receptor responses. Science’s STKE, 384, pe19.
Scheidereit, C. (2006). IkB kinase complexes: gateways to NF-kB activation and transcription. Oncogene, 25, 6685-6705.
Teaching
- 1989-Present: Lectures, Seminars and Courses at Free University Berlin and Humboldt University of Berlin. Member of various committees at Free University and Humboldt University of Berlin, International Ph.D. program, MDC and Humboldt University
- Currently training 7 PhD students (4 graduated 2003 – present)
Miscellaneous
Honors & Awards
German Cancer Prize 2005
Memberships & Duties
2000 - Steering Commitee, Max-Delbruck-Center, MDC Member/Chair
1998 - Scientific Council, MDC Elected Member
Since 1989 ad hoc reviewer of various scientific journals and funding agencies