Carmen Birchmeier

C:\Documents and Settings\imeij\My Documents\Iwan\TransCard\Website\CVs\Carmen Birchmeier

Max-Delbrück-Center for Molecular Medicine (MDC)

Robert-Rössle-Str. 10

13125 Berlin, Germany

Phone: +49 30 9406 2403

FAX:    +49 30 9406 3765

cbirch@mdc-berlin.de

http://www.mdc-berlin.de/~cbirch/

 

Objectives & Background

Our group is interested in the role of receptor protein tyrosine kinases during mouse embryonic development. We study this question by targeted mutagenesis of genes like c-met, the erbB receptors and others. Insights gained from null mutations of these genes have led to a new generation of experiments where we use the Cre-loxP technique to generate conditional tissue-specific gene knock-outs.

 

Education & Professional experience

Full Professor | Medical Faculty, FU-Berlin

2002 - present

 

Coordinator | MDC, Berlin

2002 – present. Coordinator of the MDC neuroscience program

 

Group leader | MDC, Berlin

1995 – present

 

Junior Group leader | MPG, Cologne

1989-1995, Junior Group Leader at the Max-Delbrück-Laboratory, MPG, Cologne

 

Postdoctoral training | Cold Spring Harbor Laboratory, New York

1984-1989 (since 1986 as staff scientist)

 

PhD training | University of Zurich

1980-1984, PhD

 

Studies in Biochemistry and Chemistry | University of Konstanz, UCSD (USA), and ETH Zurich

1974-1979

 

Publications

Selected (2003-2008)

Vasyutina, E., Lenhard, D. C., Wende, H., Erdmann, B., Epstein, J. A., and Birchmeier, C. (2007). RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells. PNAS 104, 4443-4448.

 

Gierl, M. S., Karoulias, N., Wende, H., Strehle, M., and Birchmeier, C. (2006). The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Genes Dev 20, 2465-2478.

 

Vasyutina, E., Stebler, J., Brand-Saberi, B., Schulz, S., Raz, E., and Birchmeier, C. (2005). CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev 19, 2187-2198.

 

Borowiak, M., Garratt, A. N., Wustefeld, T., Strehle, M., Trautwein, C., and Birchmeier, C. (2004). Met provides essential signals for liver regeneration. PNAS 101, 10608-10613.

 

Birchmeier, C., Birchmeier, W., Gherardi, E., and Vande Woude, G. F. (2003). Met, metastasis, motility and more. Nat Rev Mol Cell Biol 4, 915-925.

 

Teaching

  • Supervision of 18 PhD students (9 graduated since 2003)

 

  • PhD lecture series, MDC-Berlin

 

Miscellaneous

Honors & Awards

2002 Leibniz Award of the German Science Foundation

1989 Bennigsen Förderpreis des Landes Nordrhein-Westfahlen

1984-86 Fellowship of the Swiss Natl. Science Foundation

 

Editorial Board

2004 Editor ‘Developmental Biology’

2002 Editor European Journal of Biochemistry

 

Memberships & Duties

2004- Deputy Speaker of the SFB 665 'Developmental Disturbances of the Brain'

2004- Member of the 'Wissenschaftskommission Niedersachsen'

2002-06 Member of the Advisory Board (Life Sciences, Genomics and Biotechnology for Health) for the EU 6th framework program

2002-03 Member of the 'Council of Scientists of the Human Frontier Science Program'

2000-06 Member of the advisory board of the Helsinki Biocenter

2000-04 Member of the 'Senatsausschuss für die Angelegenheiten der SFBs' of the German Science Foundation (DFG)