Publications
2012
Gerbitz A; Sukumar M; Helm F; Wilke A; Friese C; Fahrenwaldt C; Lehmann FM; Loddenkemper C; Kammertoens T; Mautner J; Schmitt CA; Blankenstein T; Bornkamm GW
Stromal interferon-{gamma} signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice
PLoS ONE 7 (3): e34552 (2012-03-30)
Sinnecker T; Mittelstaedt P; Doerr JR; Pfueller CF; Harms L; Niendorf T; Paul F; Wuerfel J
Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study
Archives of Neurology : (2012-02-20)
Kaiser AD; Schuster K; Gadiot J; Borkner L; Daebritz H; Schmitt C; Andreesen R; Blank C
Reduced tumor-antigen density leads to PD-1/PD-L1 mediated impairment of partially exhausted CD8(+) T cells
European Journal of Immunology 42 (3): 662-671 (2012-03)
2011
Lee S; Schmitt CA; Reimann M
The Myc/macrophage tango: Oncogene-induced senescence, Myc style
Seminars in Cancer Biology 21 (6): 377-384 (2011-12)
Jing H; Kase J; Doerr JR; Milanovic M; Lenze D; Grau M; Beuster G; Ji S; Reimann M; Lenz P; Hummel M; Doerken B; Lenz G; Scheidereit C; Schmitt CA; Lee S
Opposing roles of NF-{kappa}B in anti-cancer treatment outcome unveiled by cross-species investigations
Genes & Development 25 (20): 2137-2146 (2011-10-15)
Reimann M; Schmitt CA; Lee S
Non-cell-autonomous tumor suppression: oncogene-provoked apoptosis promotes tumor cell senescence via stromal crosstalk
Journal of Molecular Medicine 89 (9): 869-875 (2011-09)
2010
Reimann M; Lee S; Loddenkemper C; Doerr JR; Tabor V; Aichele P; Stein H; Doerken B; Jenuwein T; Schmitt CA
Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence
Cancer Cell 17 (3): 262-272 (2010-03-16)
Haugstetter AM; Loddenkemper C; Lenze D; Groene J; Standfuss C; Petersen I; Doerken B; Schmitt CA
Cellular senescence predicts treatment outcome in metastasised colorectal cancer
British Journal of Cancer 103 (4): 505-509 (2010-08-10)
Rohwer N; Dame C; Haugstetter A; Wiedenmann B; Detjen K; Schmitt CA; Cramer T
Hypoxia-inducible factor 1 alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappa B
PLoS ONE 5 (8): e12038 (2010-08-10)
2007
Reimann M; Loddenkemper C; Rudolph C; Schildhauer I; Teichmann B; Stein H; Schlegelberger B; Doerken B; Schmitt CA
The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo
Blood 110 (8): 2996-3004 (2007-10-15)
Bouchard C; Lee S; Paulus-Hock V; Loddenkemper C; Eilers M; Schmitt CA
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf
Genes & Development 21 (21): 2775-2787 (2007-11-01)
Schmitt CA
Cellular senescence and cancer treatment
Biochimica et Biophysica Acta - Reviews on Cancer 1775 (1): 5-20 (2007-01)
2006
Braig M; Schmitt CA
Oncogene-induced senescence: putting the brakes on tumor development
Cancer Research 66: 2881-2884 (2006-03-15)
2005
Braig M; Lee S; Loddenkemper C; Rudolph C; Peters AH; Schlegelberger B; Stein H; Doerken B; Jenuwein T; Schmitt CA
Oncogene-induced senescence as an initial barrier in lymphoma development
Nature 436 (7051): 660-665 (2005-08-04)
Holdhoff M; Kreuzer KA; Appelt C; Scholz R; Na IK; Hildebrandt B; Riess H; Jordan A; Schmidt CA; Van Etten RA; Doerken B; LeCoutre P
Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor
Blood Cells Molecules and Diseases 34: 181-185 (2005-01-01)
Helmrich A; Lee S; O'Brien P; Doerken B; Lowe SW; Schroeck E; Schmitt CA
Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo
Oncogene 24: 4174-4182 (2005-01-01)
2004
Lee S; Doerken B; Schmitt CA
Extracorporeal photopheresis in graft-versus-host disease: ultraviolet radiation mediates T cell senescence in vivo
Transplantation 78: 484-485 (2004-01-01)
Kahlem P; Doerken B; Schmitt CA
Cellular senescence in cancer treatment: friend or foe?
Journal of Clinical Investigation 113 (2): 169-174 (2004-01)
Subklewe M; Nagy M; Schoch C; Jenisch S; Siebert R; Gesk S; Neuhaus P; Doerken B; Schmidt CA
Extramedullary manifestation of a donor-derived acute myeloid leukemia in a liver transplant patient
Leukemia 18: 2050-2053 (2004-10-07)
2003
Schmitt CA
Senescence apoptosis and therapy - cutting the lifelines of cancer
Nature Reviews Cancer 3 (4): 286-295 (2003-01-01)
Maier M; Maier-Bosse T; Schulz CU; Steinborn M; Schmitt CA; Kleen M; Staebler A
Inter and intraobserver variability in DePalma's classification of shoulder calcific tendinitis
Journal of Rheumatology 30: 1029-1031 (2003-01-01)
Lee S; Schmitt CA
Chemotherapy response and resistance
Current Opinion in Genetics & Development 13: 90-96 (2003-01-01)