Publications
2012
Nickolas TL; Schmidt-Ott KM; Canetta P; Forster C; Singer E; Sise M; Elger A; Maarouf O; Sola-Del Valle DA; O'Rourke M; Sherman E; Lee P; Geara A; Imus P; Guddati A; Polland A; Rahman W; Elitok S; Malik N; Giglio J; El-Sayegh S; Devarajan P; Hebbar S; Saggi SJ; Hahn B; Kettritz R; Luft FC; Barasch J
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage a multicenter prospective cohort study
Journal of the American College of Cardiology 59 (3): 246-255 (2012-01-17)
2011
Singer E; Elger A; Elitok S; Kettritz R; Nickolas TL; Barasch J; Luft FC; Schmidt-Ott KM
Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes
Kidney International 80 (4): 405-414 (2011-08)
Willecke R; Heuberger J; Grossmann K; Michos O; Schmidt-Ott K; Walentin K; Costantini F; Birchmeier W
The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney
Developmental Biology 360 (2): 310-307 (2011-12-15)
Wuebken A; Schmidt-Ott KM
WNT/beta-catenin signaling in polycystic kidney disease
Kidney International 80 (2): 135-138 (2011-07)
Schmidt-Ott KM
Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury--where do we stand today?
Nephrology Dialysis Transplantation 26 (3): 762-764 (2011-03)
Sise ME; Forster C; Singer E; Sola-Del Valle D; Hahn B; Schmidt-Ott KM; Barasch J; Nickolas TL
Urine neutrophil gelatinase-associated lipocalin identifies unilateral and bilateral urinary tract obstruction
Nephrology Dialysis Transplantation 26 (12): 4132-4135 (2011-12)
Paragas N; Qiu A; Zhang Q; Samstein B; Deng SX; Schmidt-Ott KM; Viltard M; Yu W; Forster CS; Gong G; Liu Y; Kulkarni R; Mori K; Kalandadze A; Ratner AJ; Devarajan P; Landry DW; D'Agati V; Lin CS; Barasch J
The Ngal reporter mouse detects the response of the kidney to injury in real time
Nature Medicine 17 (2): 216-222 (2011-02)
2010
Werth M; Walentin K; Aue A; Schoenheit J; Wuebken A; Pode-Shakked N; Vilianovitch L; Erdmann B; Dekel B; Bader M; Barasch J; Rosenbauer F; Luft FC; Schmidt-Ott KM
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex
Development 137 (22): 3835-3845 (2010-11)
Schmidt-Ott KM
ROCK inhibition facilitates tissue reconstitution from embryonic kidney cell suspensions
Kidney International 77 (5): 387-389 (2010-03)
Bao G; Clifton M; Hoette TM; Mori K; Deng SX; Qiu A; Viltard M; Williams D; Paragas N; Leete T; Kulkarni R; Li X; Lee B; Kalandadze A; Ratner AJ; Pizarro JC; Schmidt-Ott KM; Landry DW; Raymond KN; Strong RK; Barasch J
Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex
Nature Chemical Biology 6 (8): 602-609 (2010-08)
2009
Li JY; Paragas N; Ned RM; Qiu A; Viltard M; Leete T; Drexler IR; Chen X; Sanna-Cherchi S; Mohammed F; Williams D; Lin CS; Schmidt-Ott KM; Andrews NC; Barasch J
Scara5 is a ferritin receptor mediating non-transferrin iron delivery
Developmental Cell 16 (1): 35-46 (2009-01)
Lu BC; Cebrian C; Chi X; Kuure S; Kuo R; Bates CM; Arber S; Hassell J; Macneil L; Hoshi M; Jain S; Asai N; Takahashi M; Schmidt-Ott KM; Barasch J; D'Agati V; Costantini F
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
Nature Genetics 41 (12): 1295-1302 (2009-12)
Paragas N; Nickolas TL; Wyatt C; Forster CS; Sise M; Morgello S; Jagla B; Buchen C; Stella P; Sanna-Cherchi S; Carnevali ML; Mattei S; Bovino A; Argentiero L; Magnano A; Devarajan P; Schmidt-Ott KM; Allegri L; Klotman P; D'Agati V; Gharavi AG; Barasch J
Urinary NGAL marks cystic disease in HIV-associated nephropathy
Journal of the American Society of Nephrology 20 (8): 1687-1692 (2009-08)
Marlier A; Schmidt-Ott KM; Gallagher AR; Barasch J; Karihaloo A
Vegf as an epithelial cell morphogen modulates branching morphogenesis of embryonic kidney by directly acting on the ureteric bud
Mechanisms of Development 126 (3-4): 91-98 (2009-03)
2008
Schmidt-Ott KM; Barasch J
WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny
Kidney International 74 (8): 1004-1008 (2008-10)
Schmidt-Ott KM
Unraveling the role of connective tissue growth factor in diabetic nephropathy
Kidney International 73 (4): 375-376 (2008-02)
Metsuyanim S; Pode-Shakked N; Schmidt-Ott KM; Keshet G; Rechavi G; Blumental D; Dekel B
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
Stem Cells 26 (7): 1808-1817 (2008-07)
2007
Schmidt-Ott KM; Masckauchan TN; Chen X; Hirsh BJ; Sarkar A; Yang J; Paragas N; Wallace VA; Dufort D; Pavlidis P; Jagla B; Kitajewski J; Barasch J
Beta-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitors
Development 134 (17): 3177-3190 (2007-09)
Sanna-Cherchi S; Caridi G; Weng PL; Dagnino M; Seri M; Konka A; Somenzi D; Carrea A; Izzi C; Casu D; Allegri L; Schmidt-Ott KM; Barasch J; Scolari F; Ravazzolo R; Ghiggeri GM; Gharavi AG
Localization of a gene for nonsyndromic renal hypodysplasia to chromosome 1p32-33
American Journal of Human Genetics 80 (3): 539-549 (2007-03)
Schmidt-Ott KM; Mori K; Li JY; Kalandadze A; Cohen DJ; Devarajan P; Barasch J
Dual action of neutrophil gelatinase-associated lipocalin
Journal of the American Society of Nephrology 18 (2): 407-413 (2007-02)
2006
Dekel B; Metsuyanim S; Schmidt-Ott KM; Fridman E; Jacob-Hirsch J; Simon A; Pinthus J; Mor Y; Barasch J; Amariglio N; Reisner Y
Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney
Cancer Research 66 (12): 6040-6049 (2006-06-15)
Schmidt-Ott KM; Mori K; Kalandadze A; Li JY; Paragas N; Nicholas T; Devarajan P; Barasch J
Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia
Current Opinion in Nephrology and Hypertension 15 (4): 442-449 (2006-07)
Schmidt-Ott KM; Chen X; Paragas N; Levinson RS; Mendelsohn CL; Barasch J
c-kit delineates a distinct domain of progenitors in the developing kidney
Developmental Biology 299 (1): 238-249 (2006-11-01)
Schmidt-Ott KM
Nephrologists sans frontieres: the art and science of branching
Kidney International 69 (11): 1921-1923 (2006-06)
2005
Mori K; Lee HT; Rapoport D; Drexler IR; Foster K; Yang J; Schmidt-Ott KM; Chen X; Li JY; Weiss S; Mishra J; Cheema FH; Markowitz G; Suganami T; Sawai K; Mukoyama M; Kunis C; D'Agati V; Devarajan P; Barasch J
Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury
Journal of Clinical Investigation 115 (3): 610-621 (2005-03)
Schmidt-Ott KM; Yang J; Chen X; Wang H; Paragas N; Mori K; Li JY; Lu B; Costantini F; Schiffer M; Bottinger E; Barasch J
Novel regulators of kidney development from the tips of the ureteric bud
Journal of the American Society of Nephrology 16 (7): 1993-2002 (2005-07)
Zheng Z; Schmidt-Ott KM; Chua S; Foster KA; Frankel RZ; Pavlidis P; Barasch J; D'Agati VD; Gharavi AG
A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse
Proceedings of the National Academy of Sciences of the United States of America 102 (7): 2502-2507 (2005-02-15)
2004
Li JY; Ram G; Gast K; Chen X; Barasch K; Mori K; Schmidt-Ott K; Wang J; Kuo HC; Savage-Dunn C; Garrick MD; Barasch J
Detection of intracellular iron by its regulatory effect
American Journal of Physiology Cell Physiology 287 (6): C1547-C1549 (2004-12)
2003
Wernicke D; Schmidt-Ott K; Brasen JH; Moeller DE; Goebel U
A renal biopsy yields sight as well as insight
Nephrology Dialysis Transplantation 18 (9): 1937-1938 (2003-09)
2002
Phillips MI; Tang Y; Schmidt-Ott K; Qian K; Kagiyama S
Vigilant vector: heart-specific promoter in an adeno-associated virus vector for cardioprotection
Hypertension 39 (2 Pt 2): 651-655 (2002-02)
Tang Y; Schmitt-Ott K; Qian K; Kagiyama S; Phillips MI
Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases
Methods 28 (2): 259-266 (2002-10)
2001
Schmidt-Ott KM; Xu AD; Tuschick S; Liefeldt L; Kresse W; Verkhratsky A; Kettenmann H; Paul M
Hypoxia reverses dibutyryl-cAMP-induced stellation of cultured astrocytes via activation of the endothelin system
FASEB Journal 15 (7): 1227-1229 (2001-05)
2000
Schmidt-Ott KM; Kagiyama S; Phillips MI
The multiple actions of angiotensin II in atherosclerosis
Regulatory Peptides 93 (1-3): 65-77 (2000-09-25)
1999
Phillips MI; Schmidt-Ott KM
The Discovery of Renin 100 Years Ago
News in Physiological Sciences 14 (6): 271-274 (1999-12)