Publications
2012
Anders G; Mackowiak SD; Jens M; Maaskola J; Kuntzagk A; Rajewsky N; Landthaler M; Dieterich C
doRiNA: a database of RNA interactions in post-transcriptional regulation
Nucleic Acids Research 40 (1): D180-D186 (2012-01)
Milek M; Wyler E; Landthaler M
Transcriptome-wide analysis of protein-RNA interactions using high-throughput sequencing
Seminars in Cell & Developmental Biology 23 (2): 206-212 (2012-04)
2011
Zhang X; Yalcin S; Lee DF; Yeh TY; Lee SM; Su J; Mungamuri SK; Rimmele P; Kennedy M; Sellers R; Landthaler M; Tuschl T; Chi NW; Lemischka I; Keller G; Ghaffari S
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
Nature Cell Biology 13 (9): 1092-1099 (2011-07-31)
Ohrt T; Staroske W; Muetze J; Crell K; Landthaler M; Schwille P
Fluorescence cross-correlation spectroscopy reveals mechanistic insights into the effect of 2'-O-methyl modified siRNAs in living cells
Biophysical Journal 100 (12): 2981-2990 (2011-06-22)
Lebedeva S; Jens M; Theil K; Schwanhaeusser B; Selbach M; Landthaler M; Rajewsky N
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR
Molecular Cell 43 (3): 340-352 (2011-08-05)
2010
Hafner M; Landthaler M; Burger L; Khorshid M; Hausser J; Berninger P; Rothballer A; Ascano M; Jungkamp AC; Munschauer M; Ulrich A; Wardle GS; Dewell S; Zavolan M; Tuschl T
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
Cell 141 (1): 129-141 (2010-04-02)
Hafner M; Landthaler M; Burger L; Khorshid M; Hausser J; Berninger P; Rothballer A; Ascano M; Jungkamp AC; Munschauer M; Ulrich A; Wardle GS; Dewell S; Zavolan M; Tuschl T
PAR-CliP - a method to identify transcriptome-wide the binding sites of RNA binding proteins
Journal of Visualized Experiments 41: (2010-07-02)
Landthaler M
Chaperones get RISC loaded
Molecular Cell 39 (2): 161-162 (2010-07-30)
2009
Hausser J; Landthaler M; Jaskiewicz L; Gaidatzis D; Zavolan M
Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets
Genome Research 19 (11): 2009-2020 (2009-11)
Zhang Y; Landthaler M; Schlussman SD; Yuferov V; Ho A; Tuschl T; Kreek MJ
Mu opioid receptor knockdown in the substantia nigra/ventral tegmental area by synthetic small interfering RNA blocks the rewarding and locomotor effects of heroin
Neuroscience 158 (2): 474-483 (2009-01-23)
Yi R; Pasolli HA; Landthaler M; Hafner M; Ojo T; Sheridan R; Sander C; O'Carroll D; Stoffel M; Tuschl T; Fuchs E
DGCR8-dependent microRNA biogenesis is essential for skin development
Proceedings of the National Academy of Sciences of the United States of America 106 (2): 498-502 (2009-01-13)
2008
Landthaler M; Gaidatzis D; Rothballer A; Chen PY; Soll SJ; Dinic L; Ojo T; Hafner M; Zavolan M; Tuschl T
Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs
RNA 14 (12): 2580-2596 (2008-12)
2007
Landgraf P; Rusu M; Sheridan R; Sewer A; Iovino N; Aravin A; Pfeffer S; Rice A; Kamphorst AO; Landthaler M; Lin C; Socci ND; Hermida L; Fulci V; Chiaretti S; Foa R; Schliwka J; Fuchs U; Novosel A; Mueller RU; Schermer B; Bissels U; Inman J; Phan Q; Chien M; Weir DB; Choksi R; De Vita G; Frezzetti D; Trompeter HI; Hornung V; Teng G; Hartmann G; Palkovits M; Di Lauro R; Wernet P; Macino G; Rogler CE; Nagle JW; Ju J; Papavasiliou FN; Benzing T; Lichter P; Tam W; Brownstein MJ; Bosio A; Borkhardt A; Russo JJ; Sander C; Zavolan M; Tuschl T
A mammalian microRNA expression atlas based on small RNA library sequencing
Cell 129 (7): 1401-1414 (2007-06-29)
Randall G; Panis M; Cooper JD; Tellinghuisen TL; Sukhodolets KE; Pfeffer S; Landthaler M; Landgraf P; Kan S; Lindenbach BD; Chien M; Weir DB; Russo JJ; Ju J; Brownstein MJ; Sheridan R; Sander C; Zavolan M; Tuschl T; Rice CM
Cellular cofactors affecting hepatitis C virus infection and replication
Proceedings of the National Academy of Sciences of the United States of America 104 (31): 12884-12889 (2007-07-31)
2006
Landthaler M; Shen BW; Stoddard BL; Shub DA
I-BasI and I-HmuI: two phage intron-encoded endonucleases with homologous DNA recognition sequences but distinct DNA specificities
Journal of Molecular Biology 358 (4): 1137-1151 (2006-05-12)
Hickerson RP; Smith FJ; McLean WH; Landthaler M; Leube RE; Kaspar RL
SiRNA-mediated selective inhibition of mutant keratin mRNAs responsible for the skin disorder pachyonychia congenita
Annals of the New York Academy of Sciences 1082: 56-61 (2006-10)
2005
Paludan C; Schmid D; Landthaler M; Vockerodt M; Kube D; Tuschl T; Muenz C
Endogenous MHC class II processing of a viral nuclear antigen after autophagy
Science 307 (5709): 593-596 (2005-01-28)
Meister G; Landthaler M; Peters L; Chen PY; Urlaub H; Luehrmann R; Tuschl T
Identification of novel argonaute-associated proteins
Current Biology 15 (23): 2149-2155 (2005-12-06)
Coros CJ; Landthaler M; Piazza CL; Beauregard A; Esposito D; Perutka J; Lambowitz AM; Belfort M
Retrotransposition strategies of the Lactococcus lactis Ll.LtrB group II intron are dictated by host identity and cellular environment
Molecular Microbiology 56 (2): 509-524 (2005-04)
2004
Landthaler M; Lau NC; Shub DA
Group I intron homing in Bacillus phages SPO1 and SP82: a gene conversion event initiated by a nicking homing endonuclease
Journal of Bacteriology 186 (13): 4307-4314 (2004-07)
Meister G; Landthaler M; Dorsett Y; Tuschl T
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
RNA 10 (3): 544-550 (2004-03)
Shen BW; Landthaler M; Shub DA; Stoddard BL
DNA binding and cleavage by the HNH homing endonuclease I-HmuI
Journal of Molecular Biology 342 (1): 43-56 (2004-09-03)
Landthaler M; Yalcin A; Tuschl T
The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
Current Biology 14 (23): 2162-2167 (2004-12-14)
Meister G; Landthaler M; Patkaniowska A; Dorsett Y; Teng G; Tuschl T
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
Molecular Cell 15 (2): 185-197 (2004-07-23)
2003
Landthaler M; Shub DA
The nicking homing endonuclease I-BasI is encoded by a group I intron in the DNA polymerase gene of the Bacillus thuringiensis phage Bastille
Nucleic Acids Research 31 (12): 3071-3077 (2003-06-15)
2002
Landthaler M; Begley U; Lau NC; Shub DA
Two self-splicing group I introns in the ribonucleotide reductase large subunit gene of Staphylococcus aureus phage Twort
Nucleic Acids Research 30 (9): 1935-1943 (2002)
Belle A; Landthaler M; Shub DA
Intronless homing: site-specific endonuclease SegF of bacteriophage T4 mediates localized marker exclusion analogous to homing endonucleases of group I introns
Genes & Development 16 (3): 351-362 (2002)
1999
Landthaler M; Shub DA
Unexpected abundance of self-splicing introns in the genome of bacteriophage Twort: introns in multiple genes, a single gene with three introns, and exon skipping by group I ribozymes
Proceedings of the National Academy of Sciences of the United States of America 96 (12): 7005-7010 (1999-06-08)