Molecular Tumor Genetics and Immunogenetics
Head of the group
Secretariat
Our group is interested in the field of immune regulation, immunopathogenesis, tumor genetics, and translational immunology with focus on the following major areas:
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The role of homeostatic chemokine receptors in lymphoid organ development, systemic immune responses, and chronic inflammatory diseases. |
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Differentiation, trafficking and function of memory/effector T cells, especially the role of follicular B helper T cells in inflammation and autoimmunity. |
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Immunomodulatory and oncogenic functions of herpesvirus-encoded chemokine receptors. |
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The function of sphingophospholipid receptors in the immune system. |
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Target identification and validation in preclinical animal models with focus on B cell lymphoma and gastric carcinoma. |
Picture: Artistic view of an altered B cell follicle in the spleen of CXCR5-deficient mice