Publications
2012
Schumann M; Winter S; Wichner K; May C; Kuehl AA; Batra A; Siegmund B; Zeitz M; Schulzke JD; Lipp M; Hoepken UE
CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis
Mucosal Immunology : (2012-03-07)
Yndestad A; Finsen AV; Ueland T; Husberg C; Dahl CP; Oie E; Vinge LE; Sjaastad I; Sandanger O; Ranheim T; Dickstein K; Kjekshus J; Damas JK; Fiane AE; Hilfiker-Kleiner D; Lipp M; Gullestad L; Christensen G; Aukrust P
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS ONE 7 (3): e33038 (2012-03-12)
Nguyen-Hoai T; Baldenhofer G; Ahmed MS; Pham-Duc M; Gries M; Lipp M; Doerken B; Pezzutto A; Westermann J
CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model
Journal of Gene Medicine 14 (2): 128-137 (2012-02)
Hoepken UE; Rehm A
Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs
Journal of Molecular Medicine : (2012-05-11)
Nguyen-Hoai T; Baldenhofer G; Sayed Ahmed MS; Pham-Duc M; Vu MD; Lipp M; Doerken B; Pezzutto A; Westermann J
CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model
Cancer Gene Therapy 19 (1): 69-76 (2012)
Ishimaru N; Yamada A; Nitta T; Arakaki R; Lipp M; Takahama Y; Hayashi Y
CCR7 with S1P(1) signaling through AP-1 for migration of Foxp3(+) regulatory T-cells controls autoimmune exocrinopathy
American Journal of Pathology 180 (1): 199-208 (2012-01)
Nakamoto N; Ebinuma H; Kanai T; Chu PS; Ono Y; Mikami Y; Ojiro K; Lipp M; Love PE; Saito H; Hibi T
CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis
Gastroenterology 142 (2): 366-376 (2012-02)
2011
Winter S; Rehm A; Wichner K; Scheel T; Batra A; Siegmund B; Berek C; Lipp M; Hoepken UE
Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice
American Journal of Pathology 179 (2): 754-765 (2011-08)
Nemoto Y; Kanai T; Shinohara T; Ito T; Nakamura T; Okamoto R; Tsuchiya K; Lipp M; Eishi Y; Watanabe M
Luminal CD4 + T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation
Gastroenterology 141 (6): 2130-2139.e11 (2011-12)
Chyou S; Benahmed F; Chen J; Kumar V; Tian S; Lipp M; Lu TT
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells
Journal of Immunology 187 (11): 5558-5567 (2011-12-02)
Rehm A; Mensen A; Schradi K; Gerlach K; Wittstock S; Winter S; Buechner G; Doerken B; Lipp M; Hoepken UE
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs
Blood 118 (4): 1020-1033 (2011-07-28)
Azukizawa H; Doehler A; Kanazawa N; Nayak A; Lipp M; Malissen B; Autenrieth I; Katayama I; Riemann M; Weih F; Berberich-Siebelt F; Lutz MB
Steady state migratory RelB(+) Langerin(+) dermal dendritic cells mediate peripheral induction of antigen-specific CD4(+) CD25(+) Foxp3(+) regulatory T cells
European Journal of Immunology 41 (5): 1420-1434 (2011-05)
Schulze T; Golfier S; Tabeling C; Raebel K; Graeler MH; Witzenrath M; Lipp M
Sphingosine-1-phospate receptor 4 (S1P4) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model
FASEB Journal 25 (11): 4024-4036 (2011-11)
Waehre A; Halvorsen B; Yndestad A; Husberg C; Sjaastad I; Nygard S; Dahl CP; Ahmed MS; Finsen AV; Reims H; Louch WE; Hilfiker-Kleiner D; Vinge LE; Roald B; Attramadal H; Lipp M; Gullestad L; Aukrust P; Christensen G
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS ONE 6 (4): e18668 (2011-04-18)
Larsen KO; Yndestad A; Sjaastad I; Loberg EM; Goverud IL; Halvorsen B; Jia J; Andreassen AK; Husberg C; Jonasson S; Lipp M; Christensen G; Aukrust P; Skjonsberg OH
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
American Journal of Physiology Lung Cellular and Molecular Physiology 301 (1): L50-L59 (2011-07)
2010
Hoepken UE; Winter S; Achtman AH; Krueger K; Lipp M
CCR7 regulates lymphocyte egress and recirculation through body cavities
Journal of Leukocyte Biology 87 (4): 671-682 (2010-04)
Winter S; Loddenkemper C; Aebischer A; Raebel K; Hoffmann K; Meyer TF; Lipp M; Hoepken UE
The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation
Journal of Molecular Medicine 88 (11): 1169-1180 (2010-11)
Golfier S; Kondo S; Schulze T; Takeuchi T; Vassileva G; Achtman AH; Graeler MH; Abbondanzo SJ; Wiekowski M; Kremmer E; Endo Y; Lira SA; Bacon KB; Lipp M
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4
FASEB Journal 24 (12): 4701-4710 (2010-12)
Ishimaru N; Nitta T; Arakaki R; Yamada A; Lipp M; Takahama Y; Hayashi Y
In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy
PLoS ONE 5 (1): e8588 (2010-01-05)
2009
Kuwabara T; Ishikawa F; Yasuda T; Aritomi K; Nakano H; Tanaka Y; Okada Y; Lipp M; Kakiuchi T
CCR 7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells
Journal of Immunology 183 (4): 2513-2521 (2009-08-15)
van de Pavert SA; Olivier BJ; Goverse G; Vondenhoff MF; Greuter M; Beke P; Kusser K; Hoepken UE; Lipp M; Niederreither K; Blomhoff R; Sitnik K; Agace WW; Randall TD; de Jonge WJ; Mebius RE
Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation
Nature Immunology 10 (11): 1193-1199 (2009-11)
Nitta T; Nitta S; Lei Y; Lipp M; Takahama Y
CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens
Proceedings of the National Academy of Sciences of the United States of America 106 (40): 17129-17133 (2009-10-06)
Rueder C; Hoepken UE; Wolf J; Mittruecker HW; Engels B; Erdmann B; Wollenzin S; Uckert W; Doerken B; Rehm A
The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells
Journal of Clinical Investigation 119 (8): 2184-2203 (2009-08)
de Jager SC; Cante-Barrett K; Bot I; Husberg C; van Puijvelde GH; van Santbrink PJ; Yndestad A; van den Oever JM; Kuiper J; van Berkel TJ; Lipp M; Zwaginga JJ; Fibbe WE; Aukrust P; Biessen EA
Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras
Transplantation 88 (5): 631-639 (2009-09-15)
Wolf SA; Steiner B; Wengner AM; Lipp M; Kammertoens T; Kempermann G
Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus
FASEB Journal 23 (9): 3121-3128 (2009-09)
Rehm A; Anagnostopoulos I; Gerlach K; Broemer M; Scheidereit C; Joehrens K; Huebler M; Hetzer R; Stein H; Lipp M; Doerken B; Hoepken UE
Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma
International Journal of Cancer 125 (10): 2367-2374 (2009-11-15)
Achtman AH; Hoepken UE; Bernert C; Lipp M
CCR7-deficient mice develop atypically persistent germinal centers in response to thymus-independent type 2 antigens
Journal of Leukocyte Biology 85 (3): 409-417 (2009-03)
Buonamici S; Trimarchi T; Ruocco MG; Reavie L; Cathelin S; Mar BG; Klinakis A; Lukyanov Y; Tseng JC; Sen F; Gehrie E; Li M; Newcomb E; Zavadil J; Meruelo D; Lipp M; Ibrahim S; Efstratiadis A; Zagzag D; Bromberg JS; Dustin ML; Aifantis I
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia
Nature 459 (7249): 1000-1004 (2009-06-18)
2008
Ladi E; Schwickert TA; Chtanova T; Chen Y; Herzmark P; Yin X; Aaron H; Chan SW; Lipp M; Roysam B; Robey EA
Thymocyte-dendritic cell interactions near sources of CCR7 ligands in the thymic cortex
Journal of Immunology 181 (10): 7014-7023 (2008-11-15)
2007
Arnold CN; Campbell DJ; Lipp M; Butcher EC
The germinal center response is impaired in the absence of T cell-expressed CXCR5
European Journal of Immunology 37 (1): 100-109 (2007-01)
Schneider MA; Meingassner JG; Lipp M; Moore HD; Rot A
CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells
Journal of Experimental Medicine 204 (4): 735-745 (2007-04-16)
Menning A; Hoepken UE; Siegmund K; Lipp M; Hamann A; Huehn J
Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets
European Journal of Immunology 37 (6): 1575-1583 (2007-05-02)
Kahnert A; Hoepken UE; Stein M; Bandermann S; Lipp M; Kaufmann SH
Mycobacterium tuberculosis triggers formation of lymphoid structure in murine lungs
Journal of Infectious Diseases 195 (1): 46-54 (2007-01-01)
Hoepken UE; Wengner AM; Loddenkemper C; Stein H; Heimesaat MM; Rehm A; Lipp M
CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity
Blood 109 (3): 886-895 (2007-02-01)
Wengner AM; Hoepken UE; Petrow PK; Hartmann S; Schurigt U; Braeuer R; Lipp M
CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritis
Arthritis and Rheumatism 56 (10): 3271-3283 (2007-10)
Thirunarayanan N; Cifire F; Fichtner I; Posner S; Benga J; Reiterer P; Kremmer E; Koelble K; Lipp M
Enhanced tumorigenicity of fibroblasts transformed with human herpesvirus 8 chemokine receptor vGPCR by successive passage in nude and immunocompetent mice
Oncogene 26 (39): 5702-5712 (2007-08-23)
Westermann J; Nguyen-Hoai T; Baldenhofer G; Hoepken UE; Lipp M; Doerken B; Pezzutto A
CCL19 (ELC) as an adjuvant for DNA vaccination: induction of a TH1-type T-cell response and enhancement of antitumor immunity
Cancer Gene Therapy 14 (6): 523-532 (2007-06)
2006
Sakai N; Wada T; Yokoyama H; Lipp M; Ueha S; Matsushima K; Kaneko S
Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis
Proceedings of the National Academy of Sciences of the United States of America 103: 14098-14103 (2006-09-19)
Zhao C; Wood MW; Galyov EE; Hoepken UE; Lipp M; Bodmer HC; Tough DF; Carter RW
Salmonella typhimurium infection triggers dendritic cells and macrophages to adopt distinct migration patterns in vivo
European Journal of Immunology 36: 2939-2950 (2006-10-18)
Rasheed AU; Rahn HP; Sallusto F; Lipp M; Mueller G
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression
European Journal of Immunology 36: 1892-1903 (2006-06-22)
Kurobe H; Liu C; Ueno T; Saito F; Ohigashi I; Seach N; Arakaki R; Hayashi Y; Kitagawa T; Lipp M; Boyd RL; Takahama Y
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance
Immunity 24: 165-177 (2006-02-01)
Jang MH; Sougawa N; Tanaka T; Hirata T; Hiroi T; Tohya K; Guo Z; Umemoto E; Ebisuno Y; Yang BG; Seoh JY; Lipp M; Kiyono H; Miyasaka M
CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes
Journal of Immunology 176: 803-810 (2006-01-15)
Schreiber T; Ehlers S; Aly S; Hoelscher A; Hartmann S; Lipp M; Lowe JB; Hoelscher C
Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis
Journal of Immunology 176: 1131-1140 (2006-01-15)
2005
Liu C; Ueno T; Kuse S; Saito F; Nitta T; Piali L; Nakano H; Kakiuchi T; Lipp M; Hollander GA; Takahama Y
Role of CCL21 in recruitment of T precursor cells to fetal thymus
Blood 105: 31-39 (2005-01-01)
Lipp M
Chemokine-controlled migration in lymphoid organogenesis and the systemic organization of immunity
Cell Migration in Development and Disease : 251-273 (2005-01-01)
Junt T; Fink K; Foerster R; Senn B; Lipp M; Muramatsu M; Zinkernagel RM; Ludewig B; Hengartner H
CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses
Journal of Immunology 175: 7109-7116 (2005-12-01)
Steinmetz OM; Panzer U; Kneissler U; Harendza S; Lipp M; Helmchen U; Stahl RAK
BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection
Kidney International 67: 1616-1621 (2005-01-01)
Hoepken UE; Lehmann I; Droese J; Lipp M; Schueler T; Rehm A
The ratio between dendritic cells and T cells determines the outcome of their encounter: Proliferation versus deletion
European Journal of Immunology 35: 2851-2863 (2005-09-23)
Kursar M; Hoepken UE; Koch M; Koehler A; Lipp M; Kaufmann SH; Mittruecker HW
Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection
Journal of Experimental Medicine 201 (9): 1447-1457 (2005-05-02)
Debes GF; Arnold CN; Young AJ; Krautwald S; Lipp M; Hay JB; Butcher EC
Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
Nature Immunology 6: 889-894 (2005-08-14)
2004
Ekland EH; Forster R; Lipp M; Cyster JG
Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells
Journal of Immunology 172: 4700-4708 (2004-01-01)
Ueno T; Saito F; Gray DHD; Kuse S; Hieshima K; Nakano H; Kakiuchi T; Lipp M; Boyd RL; Takahama Y
CCR7 signals are essential for cortex-medulla migration of developing thymocytes
Journal of Experimental Medicine 200 (4): 493-505 (2004-08-16)
Martin-Fontecha A; Thomsen LL; Brett S; Gerard C; Lipp M; Lanzavecchia A; Sallusto F
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for TH1 priming
Nature Immunology 5: 1260-1265 (2004-01-01)
Hoepken UE; Droese J; Li JP; Joergensen J; Breitfeld D; Zerwes HG; Lipp M
The chemokine receptor CCR7 controls lymph node-dependent cytotoxic T cell priming in alloimmune responses
European Journal of Immunology 34: 461-470 (2004-01-01)
Martin AP; Coronel EC; Sano G; Chen SC; Vassileva G; Canasto-Chibuque C; Sedgwick JD; Frenette PS; Lipp M; Furtado GC; Lira SA
A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21
Journal of Immunology 173: 4791-4798 (2004-10-15)
Hoepken UE; Lipp M
All roads lead to rome: triggering dendritic cell migration
Immunity 20: 244-246 (2004-03-01)
Francavilla V; Accapezzato D; De Salvo M; Rawson P; Cosimi O; Lipp M; Cerino A; Cividini A; Mondelli MU; Barnaba V
Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms
European Journal of Immunology 34: 427-437 (2004-01-01)
Droese J; Mokros T; Hermosilla R; Schuelein R; Lipp M; Hoepken UE; Rehm A
HCMV-encoded chemokine receptor US28 employs multiple routes for internalization
Biochemical and Biophysical Research Communications 322: 42-49 (2004-09-10)
Junt T; Scandella E; Foerster R; Krebs P; Krautwald S; Lipp M; Hengartner H; Ludewig B
Impact of CCR7 on priming and distribution of antiviral effector and memory CTL
Journal of Immunology 173: 6684-6693 (2004-01-01)
Lipp M; Mueller G
Lymphoid organogenesis: getting the green light from RORgammat
Nature Immunology 5: 12-14 (2004-01-01)
Hoepken UE; Achtman AH; Krueger K; Lipp M
Distinct and overlapping roles of CXCR5 and CCR7 in B-1 cell homing and early immunity against bacterial pathogens
Journal of Leukocyte Biology 76: 709-718 (2004-01-01)
2003
Graeler MH; Grosse R; Kusch A; Kremmer E; Gudermann T; Lipp M
The sphingosine 1-phosphate receptor S1P4regulates cell shape and motility via coupling to Gi and G12/13
Journal of Cellular Biochemistry 89: 507-519 (2003-01-01)
Mueller G; Lipp M
Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development
Current Opinion in Immunology 15: 217-224 (2003-01-01)
Martin-Fontecha A; Sebastiani S; Hoepken UE; Uguccioni M; Lipp M; Lanzavecchia A; Sallusto F
Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming
Journal of Experimental Medicine 198 (4): 615-621 (2003-08-18)
Dieli F; Poccia F; Lipp M; Sireci G; Caccamo N; Di Sano C; Salerno A
Differentiation of effector/memory V ae 2 T cells and migratory routes in lymph nodes or inflammatory sites
Journal of Experimental Medicine 198 (3): 391-397 (2003-08-04)
Mueller G; Lipp M
Shaping up adaptive immunity: The impact of CCR7 and CXCR5 on lymphocyte trafficking
Microcirculation 10: 325-334 (2003-01-01)
Ohl L; Henning G; Krautwald S; Lipp M; Hardtke S; Bernhardt G; Pabst O; Foerster R
Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs
Journal of Experimental Medicine 197 (9): 1199-1204 (2003-05-05)
Prinz M; Heikenwalder M; Junt T; Schwarz P; Glatzel M; Heppner FL; Fu YX; Lipp M; Aguzzi A
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
Nature 425: 957-962 (2003-01-01)
Schlegelberger B; Lipp M
Hochmaligne B-Zell-Lymphome
Molekularmedizinische Grundlagen von haematologischen Neoplasien : 456-478 (2003-01-01)
Mueller G; Reiterer P; Hoepken UE; Golfier S; Lipp M
Role of homeostatic chemokine and sphingosine-1-phosphate receptors in the organization of lymphoid tissue
Annals of the New York Academy of Sciences 987: 107-116 (2003-04-01)
Mueller G; Hoepken UE; Lipp M
The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity
Immunological Reviews 195: 117-135 (2003-01-01)
Smith JR; Braziel RM; Paoletti S; Lipp M; Uguccioni M; Rosenbaum JT
Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma
Blood 101: 815-821 (2003-01-01)
Bonhagen K; Liesenfeld O; Stadecker MJ; Hutloff A; Erb K; Coyle AJ; Lipp M; Kroczek RA; Kamradt T
ICOS+Th cells produce distinct cytokines in different mucosal immune responses
European Journal of Immunology 33: 392-401 (2003-01-01)
2002
Kusch A; Tkachuk S; Lutter S; Haller H; Dietz R; Lipp M; Dumler I
Monocyte-expressed urokinase regulates human vascular smooth muscle cell migration in a coculture model
Biological Chemistry 383: 217-221 (2002-01-01)
Rappert A; Biber K; Nolte C; Lipp M; Schubel A; Lu B; Gerard NP; Gerard C; Boddeke HWGM; Kettenmann H
Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia
Journal of Immunology 168 (7): 3221-3226 (2002-04-01)
Ueno T; Hara K; Willis MS; Malin MA; Hoepken UE; Gray DHD; Matsushima K; Lipp M; Springer TA; Boyd RL; Yoshie O; Takahama Y
Role for CCR7 Ligands in the emigration of newly generated T lymphocytes from the neonatal thymus
Immunity 16: 205-218 (2002-01-01)
Finke D; Acha-Orbea H; Mattis A; Lipp M; Kraehenbuhl JP
CD4+CD3- cells induce Peyer's patch development: role of alpha4 beta1 integrin activation by CXCR5
Immunity 17: 363-373 (2002-01-01)
Reif K; Ekland EH; Ohl L; Nakano H; Lipp M; Foerster R; Cyster JG
Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position
Nature 416: 94-99 (2002-01-01)
Valmori D; Scheibenbogen C; Dutoit V; Nagorsen D; Asemissen AM; Rubio-Godoy V; Rimoldi D; Guillaume P; Romero P; Schadendorf D; Lipp M; Dietrich PY; Thiel E; Cerottini JC; Lienard D; Keilholz U
Circulating tumor-reactive CD8+ T cells in melanoma patients contain a CD45RA+CCR7- effector subset exerting ex vivo tumor-specific cytolytic activity
Cancer Research 62: 1743-1750 (2002-01-01)
Mokros T; Rehm A; Droese J; Oppermann M; Lipp M; Hoepken UE
Surface expression and endocytosis of the human cytomegalovirus-encoded chemokine receptor US28 is regulated by agonist-independent phosphorylation
Journal of Biological Chemistry 277: 45122-45128 (2002-01-01)
Hauck L; Kaba RG; Lipp M; Dietz R; von Harsdorf R
Regulation of E2F1-dependent gene transcription and apoptosis by the ETS-related transcription factor GABPgamma1
Molecular and Cellular Biology 22: 2147-2158 (2002-01-01)
Banas B; Woernle M; Berger T; Nelson PJ; Cohen CD; Kretzler M; Pfirstinger J; Mack M; Lipp M; Groene HJ; Schloendorff D
Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis
Journal of Immunology 168 (9): 4301-4307 (2002-01-01)
Hoepken UE; Foss HD; Meyer D; Hinz M; Leder K; Stein H; Lipp M
Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs
Blood 99: 1109-1116 (2002-01-01)
Mueller G; Hoepken UE; Stein H; Lipp M
Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors
Journal of Leukocyte Biology 72: 1-8 (2002-01-01)
Okada T; Ngo VN; Ekland EH; Foerster R; Lipp M; Littman DR; Cyster JG
Chemokine requirements for B cell entry to lymph nodes and Peyers patches
Journal of Experimental Medicine 196 (1): 65-75 (2002-07-01)
2001
Bardi G; Lipp M; Baggiolini M; Loetscher P
The T cell chemokine receptor CCR7 is internalized on stimulation with ELC, but not with SLC
European Journal of Immunology 31: 3291-3297 (2001-01-01)
Holst PJ; Rosenkilde MM; Manfra D; Chen SC; Wiekowski MT; Holst B; Cifire F; Lipp M; Schwartz TW; Lira SA
Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity
Journal of Clinical Investigation 108 (12): 1789-1796 (2001-12)
Mueller G; Lipp M
Signal transduction by the chemokine receptor CXCR5: Structural requirements for G protein activation analyzed by chimeric CXCR1/CXCR5 molecules
Biological Chemistry 382: 1387-1397 (2001-01-01)
Henning G; Ohl H; Junt T; Reiterer P; Brinkmann V; Nakano H; Hohenberger W; Lipp M; Foerster R
CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: Modulation by FTY720
Journal of Experimental Medicine 194 (12): 1875-1881 (2001-12-17)
Ishikawa S; Sato T; Abe M; Nagai S; Onai N; Yoneyama H; Zhang YY; Suzuki T; Hashimoto S; Shirai T; Lipp M; Matsushima K
Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC
Journal of Experimental Medicine 193 (12): 1393-1402 (2001-06-18)
Ugolini S; Arpin C; Anfossi N; Walzer T; Cambiaggi A; Foerster R; Lipp M; Toes REM; Melief CJ; Marvel J; Vivier E
Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells
Nature Immunology 2: 430-435 (2001-01-01)
Champagne P; Ogg GS; King AS; Knabenhans C; Ellefsen K; Nobile M; Appay V; Rizzardi GP; Fleury S; Lipp M; Foerster R; Rowland-Jones S; Sekaly RP; McMichael AJ; Pantaleo G
Skewed maturation of memory HIV-specific CD8 T lymphocytes
Nature 410 (6824): 106-111 (2001-03-01)
Lange R; Peng X; Wimmer E; Lipp M; Bernhardt G
The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin
Virology 285: 218-227 (2001-07-05)
2000
Pabst O; Foerster R; Lipp M; Engel H; Arnold H-H
NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue
EMBO Journal 19: 2015-2023 (2000-01-01)
Kusch A; Tkachuk S; Haller H; Dietz R; Gulba DC; Lipp M; Dumler I
Urokinase stimulates human vascular smooth muscle cell migration via a phosphatidylinositol 3-kinase-tyk2 interaction
Journal of Biological Chemistry 275: 39466-39473 (2000-01-01)
Solecki D; Bernhardt G; Lipp M; Wimmer E
Identification of a nuclear respiratory factor-1 binding site within the core promoter of the human polio virus receptor/CD155 gene
Journal of Biological Chemistry 275: 12453-12462 (2000-01-01)
Ansel KM; Ngo VN; Hyman PL; Luther SA; Foerster R; Sedgwick JD; Browning JL; Lipp M; Cyster JG
A chemokine-driven positive feedback loop organizes lymphoid follicles
Nature 406: 309-314 (2000-07-20)
Lipp M; Foerster R; Schubel A; Burgstahler R; Mueller G; Breitfeld D; Kremmer E; Wolf E
Functional organization of secondary lymphoid organs by homeostatic chemokines
European Cytokine Network 11 (3): 504-505 (2000-09-01)
Cook DN; Prosser DM; Forster R; Zhang J; Kuklin NA; Abbondanzo SJ; Niu X-D; Chen SC; Manfra DJ; Wiekowski MT; Sullivan LM; Smith SR; Greenberg HB; Narula SK; Lipp M; Lira SA
CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue
Immunity 12 (5): 495-503 (2000-05-01)
Van Brocklyn JR; Graeler MH; Bernhardt G; Hobson JP; Lipp M; Spiegel S
Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6
Blood 95: 2624-2629 (2000-04-15)
de Boer BA; Voigt I; Kim HJ; Camacho SA; Lipp M; Foerster R; Berek C
Affinity maturation in ectopic germinal centers
Current Topics in Microbiology and Immunology 251: 191-195 (2000-01-01)
Voigt I; Camacho SA; de Boer BA; Lipp M; Foerster R; Berek C
CXCR5-deficient mice develop functional germinal centers in the splenic T cell zone
European Journal of Immunology 30: 560-567 (2000-02-01)
Lipp M; Burgstahler R; Mueller G; Pevzner V; Kremmer E; Wolf E; Forster R
Functional organization of secondary lymphoid organs by the chemokine system
Current Topics in Microbiology and Immunology 251: 173-179 (2000-01-01)
Dunbar PR; Smith CL; Chao D; Salio M; Shepherd D; Mirza F; Lipp M; Lanzavecchia A; Sallusto F; Evans A; Russell JR; Harris AL; Cerundolo V
A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response
Journal of Immunology 165: 6644-6652 (2000-12-01)
Pevzner V; Kraft R; Kostka S; Lipp M
Phosphorylation of Oct-2 at sites located in the POU domain induces differential down-regulation of Oct-2 DNA-binding ability
Biochemical Journal 347: 29-35 (2000-04-01)
Breitfeld D; Ohl L; Kremmer E; Ellwart J; Sallusto F; Lipp M; Foerster R
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
Journal of Experimental Medicine 192 (11): 1545-1551 (2000-12-04)
Schaerli P; Willimann K; Lang AB; Lipp M; Loetscher P; Moser B
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
Journal of Experimental Medicine 192 (11): 1553-1562 (2000-12-04)
1999
Lipp M
Navigation of lymphocyte subsets by the chemokine system
European Cytokine Network 10: 265-266 (1999-06-01)
Pevzner V; Wolf I; Burgstahler R; Foerster R; Lipp M
Regulation of expression of chemokine receptor BLR1/CXCR5 during B cell maturation
Mechanisms of B Cell Neoplasia. Proceedings oft the Workshop held at the Basel Institute for Immunology 4th-6th October 1998 : 79-85 (1999-01-01)
Walker LSK; Gulbranson-Judge A; Flynn S; Brocker T; Raykundalia C; Goodall M; Foerster R; Lipp M; Lane P
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers
Journal of Experimental Medicine 190 (8): 1115-1122 (1999-10-18)
Graeler MH; Bernhardt G; Lipp M
A lymphoid tissue-specific receptor, EDG6, with potential immune modulatory functions mediated by extracellular lysophospholipids
Mechanisms of B Cell Neoplasia : Proceedings of the Workshop held at the Basel Institute for Immunology 4th-6th October 1998 : 131-137 (1999-01-01)
Schabath R; Mueller G; Schubel A; Kremmer E; Lipp M; Forster R
The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation
Journal of Leukocyte Biology 66: 996-1004 (1999-12-01)
Sallusto F; Palermo B; Lenig D; Miettinen M; Matikainen S; Julkunen I; Foerster R; Burgstahler R; Lipp M; Lanzavecchia A
Distinct patterns and kinetics of chemokine production regulate dendritic cell function
European Journal of Immunology 29: 1617-1625 (1999-05-01)
Sallusto F; Kremmer E; Palermo B; Hoy A; Ponath P; Qin SX; Foerster R; Lipp M; Lanzavecchia A
Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells
European Journal of Immunology 29 (6): 2037-2045 (1999-06-01)
Foerster R; Schubel A; Breitfeld D; Kremmer E; Renner-Mueller I; Wolf E; Lipp M
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
Cell 99 (1): 23-33 (1999-10-01)
Solecki D; Wimmer E; Lipp M; Bernhardt G
Identification and characterization of the cis-acting elements of human CD155 gene core promoter
Journal of Biological Chemistry 274: 1791-1800 (1999-01-15)
Sallusto F; Lenig D; Foerster R; Lipp M; Lanzavecchia A
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
Nature 401 (6754): 708-712 (1999-10-14)
1998
Foerster R; Kremmer E; Schubel A; Breitfeld D; Kleinschmidt A; Nerl C; Bernhardt G; Lipp M
Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation
Journal of Immunology 160: 1522-1531 (1998-01-01)
Wolf I; Pevzner V; Kaiser E; Bernhardt G; Claudio E; Siebenlist U; Foerster R; Lipp M
Downstream activation of a TATA-less promoter by Oct-2, Bob1, and NF-kappaB directs expression of the homing receptor BLR1 to mature B cells
Journal of Biological Chemistry 273 (44): 28831-28836 (1998-10-30)
Graeler MH; Bernhardt G; Lipp M
EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue
Genomics 53 (2): 164-169 (1998-10-15)
1997
Solecki D; Schwarz S; Wimmer E; Lipp M; Bernhardt G
The promoters for human and monkey poliovirus receptors: requirements for basic and cell type specific activity
Journal of Biological Chemistry 272: 5579-5586 (1997-01-01)
Foerster R; Schweigard G; Johann S; Emrich T; Kremmer E; Nerl C; Lipp M
Abnormal expression of the b cell homing chemokine receptor blr1 during the progression of acquired immunodeficiency syndrome
Blood 90 (2): 520-525 (1997-07-15)
Mattis AE; Bernhardt G; Lipp M; Foerster R
Analyzing cytotoxic T lymphocyte activity: a simple and reliable flow cytometry based assay
Journal of Immunological Methods 204: 135-142 (1997-01-01)
1996
Foerster R; Mattis A; Kremmer E; Wolf E; Brem G; Lipp M
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
Cell 87 (6): 1037-1047 (1996-12-13)
Oswald F; Dobner T; Lipp M
The E2F transcription factor activates a replication-dependet human H2A gene in early S phase of the cell cycle
Molecular and Cellular Biology 16 (5): 1889-1895 (1996-01-01)
1995
Speth C; Luz A; Strauss PG; Wendel S; Zeidler R; Dorn S; Erfle V; Brem G; Lipp M; Schmidt J
Akv murine leukemia virus enhances lymphomagenesis in myc-kappa transgenic and in wild-type mice
Virology 206 (1): 93-99 (1995-01-01)
Johann S; Bluemel G; Lipp M; Foerster R
A versatile flow cytometry-based assay for the determination of short- and long-term natural killer cell activity
Journal of Immunological Methods 185 (2): 209-216 (1995-01-01)
Johann S; Zoller C; Haas S; Bluemel G; Lipp M; Foerster R
Sulfated polysaccharide anticoagulants suppress natural killer cell activity in vitro
Thrombosis and Haemostasis 74 (4): 998-1002 (1995-10)
Burgstahler R; Kempkes B; Steube K; Lipp M
Expression of the chemokine receptor BLR2/EBI1 is specifically transactivated by Epstein-Barr Virus nuclear antigen 2
Biochemical and Biophysical Research Communications 215 (2): 737-743 (1995-10-13)
1994
Mai B; Lipp M
Cloning and chromosomal organization of a gene encoding a putative amino-acid permease from Saccharomyces cerevisiae
Gene 143: 129-133 (1994-01-01)
Foerster R; Emrich T; Kremmer E; Lipp M
Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells
Blood 84 (3): 830-840 (1994-08-01)
Emrich T; Foerster R; Lipp M
Transmembrane topology of the lymphocyte-specific G- protein- coupled receptor BLR1: analysis by flow cytometry and immunocytochemistry
Cellular and Molecular Biology 40: 413-419 (1994-01-01)
Oswald F; Lovec H; Moeroey T; Lipp M
E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions
Oncogene 9 (7): 2029-2036 (1994-07)
Lauer U; Weiss L; Lipp M; Hofschneider PH; Kekule AS
The hepatitis B virus preS2/St transactivator utilizes AP-1 and other transcription factors for transactivation
Hepatology 19: 23-31 (1994-01-01)
Batsche E; Lipp M; Cremisi C
Transcriptional repression and activation in the same cell type of the human c-MYC promoter by the retinoblastoma gene protein: antagonisation of both effects by SV40 T antigen
Oncogene 9 (8): 2235-2243 (1994-08)
Zeidler R; Joos S; Delecluse H-J; Klobeck G; Vuillaume M; Lenoir GM; Bornkamm GW; Lipp M
Breakpoints of Burkitt`s lymphoma t(8;22) translocations map within a distance of 300 kb downstream of MYC
Genes Chromosomes & Cancer 9: 282-287 (1994-01-01)
Foerster R; Wolf I; Kaiser E; Lipp M
Selective expression of the murine homologue of the G- protein- coupled receptor BLR1 in B cell differentiation, B cell neoplasia and defined areas of the cerebellum
Cellular and Molecular Biology 40: 381-387 (1994-01-01)