Publications
2012
Voutilainen M; Lindfors PH; Lefebvre S; Ahtiainen L; Fliniaux I; Rysti E; Murtoniemi M; Schneider P; Schmidt-Ullrich R; Mikkola ML
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5744-5749 (2012-04-10)
Blackburn J; Ohazama A; Kawasaki K; Otsuka-Tanaka Y; Liu B; Honda K; Rountree RB; Hu Y; Kawasaki M; Birchmeier W; Schmidt-Ullrich R; Kinoshita A; Schutte BC; Hammond NL; Dixon MJ; Sharpe PT
The role of Irf6 in tooth epithelial invagination
Developmental Biology 365 (1): 61-70 (2012-05-01)
Hinz M; Coel Arslan S; Scheidereit C
It takes two to tango: IkappaBs, the multifunctional partners of NF-kappaB
Immunological Reviews 246 (1): 59-76 (2012-03)
2011
Coel Arslan S; Scheidereit C
The prevalence of TNF{alpha}-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay
PLoS ONE 6 (10): e26069 (2011-10-10)
Haeaerae O; Fujimori S; Schmidt-Ullrich R; Hartmann C; Thesleff I; Mikkola ML
Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis
Development 138 (13): 2681-2691 (2011-07)
Jing H; Kase J; Doerr JR; Milanovic M; Lenze D; Grau M; Beuster G; Ji S; Reimann M; Lenz P; Hummel M; Doerken B; Lenz G; Scheidereit C; Schmitt CA; Lee S
Opposing roles of NF-{kappa}B in anti-cancer treatment outcome unveiled by cross-species investigations
Genes & Development 25 (20): 2137-2146 (2011-10-15)
2010
Hinz M; Stilmann M; Coel Arslan S; Khanna KK; Dittmar G; Scheidereit C
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
Molecular Cell 40 (1): 63-74 (2010-10-08)
Rauch A; Seitz S; Baschant U; Schilling AF; Illing A; Stride B; Kirilov M; Mandic V; Takacz A; Schmidt-Ullrich R; Ostermay S; Schinke T; Spanbroek R; Zaiss MM; Angel PE; Lerner UH; David JP; Reichardt HM; Amling M; Schuetz G; Tuckermann JP
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor
Cell Metabolism 11 (6): 517-531 (2010-06-09)
2009
Schneider MR; Schmidt-Ullrich R; Paus R
The hair follicle as a dynamic miniorgan
Current Biology 19 (3): R132-T142 (2009-02-10)
Roel G; Gent YY; Peterson-Maduro J; Verbeek FJ; Destree O
Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis
International Journal of Developmental Biology 53 (1): 81-89 (2009)
Stilmann M; Hinz M; Coel Arslan S; Zimmer A; Schreiber V; Scheidereit C
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation
Molecular Cell 36 (3): 365-378 (2009-11-13)
Rehm A; Anagnostopoulos I; Gerlach K; Broemer M; Scheidereit C; Joehrens K; Huebler M; Hetzer R; Stein H; Lipp M; Doerken B; Hoepken UE
Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma
International Journal of Cancer 125 (10): 2367-2374 (2009-11-15)
Zhang Y; Tomann P; Andl T; Gallant NM; Huelsken J; Jerchow B; Birchmeier W; Paus R; Piccolo S; Mikkola ML; Morrisey EE; Overbeek PA; Scheidereit C; Millar SE; Schmidt-Ullrich R
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction
Developmental Cell 17 (1): 49-61 (2009-07)
2008
Zhang Y; Andl T; Yang SH; Teta M; Liu F; Seykora JT; Tobias JW; Piccolo S; Schmidt-Ullrich R; Nagy A; Taketo MM; Dlugosz AA; Millar SE
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate
Development 135 (12): 2161-2172 (2008-06)
Liu F; Chu EY; Watt B; Zhang Y; Gallant NM; Andl T; Yang SH; Lu MM; Piccolo S; Schmidt-Ullrich R; Taketo MM; Morrisey EE; Atit R; Dlugosz AA; Millar SE
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis
Developmental Biology 313 (1): 210-224 (2008-01-01)
Lovas A; Radke D; Albrecht D; Yilmaz ZB; Moeller U; Habenicht AJ; Weih F
Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts
BMC Genomics 9: 606 (2008)
2007
Weichert W; Boehm M; Gekeler V; Bahra M; Langrehr J; Neuhaus P; Denkert C; Imre G; Weller C; Hofmann HP; Niesporek S; Jacob J; Dietel M; Scheidereit C; Kristiansen G
High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis
British Journal of Cancer 97: 523-530 (2007-07-10)
Hinz M; Scheidereit C
Striking back at the activator: how IkappaB kinase terminates antigen receptor responses
Science's STKE Signal Transduction Knowledge Environment 384: pe19 (2007-05-01)
Oeckinghaus A; Wegener E; Welteke V; Ferch U; Coel Arslan S; Ruland J; Scheidereit C; Krappmann D
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
EMBO Journal 26 (22): 4634-4645 (2007-11-14)
Hinz M; Broemer M; Coel Arslan S; Otto A; Mueller EC; Dettmer R; Scheidereit C
Signal-responsiveness of Ikappa B kinases is determined by Cdc37-assisted transient interaction with Hsp90
Journal of Biological Chemistry 282 (44): 32311-32319 (2007-11-02)
Henke N; Schmidt-Ullrich R; Dechend R; Park JK; Qadri F; Wellner M; Obst M; Gross V; Dietz R; Luft FC; Scheidereit C; Mueller DN
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage
Circulation Research 101 (3): 268-276 (2007-08-03)
2006
Visekruna A; Joeris T; Seidel D; Kroesen A; Loddenkemper C; Zeitz M; Kaufmann SH; Schmidt-Ullrich R; Steinhoff U
Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis
Journal of Clinical Investigation 116 (12): 3195-3203 (2006-12)
Scheidereit C
IkappaB kinase complexes: gateways to NF-kappaB activation and transcription
Oncogene 25 (51): 6685-6705 (2006-10-30)
Scheidereit C; Krappmann D
NF-kappaB pathway
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1286-1292 (2006-07-05)
Schmidt-Ullrich R; Tobin DJ; Lenhard D; Schneider P; Paus R; Scheidereit C
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth
Development 133 (6): 1045-1057 (2006-03)
Wegener E; Oeckinghaus A; Papadopoulou N; Lavitas L; Schmidt-Supprian M; Ferch U; Mak TW; Ruland J; Heissmeyer V; Krappmann D
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation
Molecular Cell 23 (1): 13-23 (2006-07-07)
2005
Unterstab G; Ludwig S; Anton A; Planz O; Dauber B; Krappmann D; Heins G; Ehrhardt C; Wolff T
Viral targeting of the interferon-beta-inducing Traf family member-associated NF-kappaB activator (TANK)-binding kinase-1
Proceedings of the National Academy of Sciences of the United States of America 102: 13640-13645 (2005-09-09)
Schmidt-Ullrich R; Paus R
Molecular principles of hair follicle induction and morphogenesis
BioEssays 27: 247-261 (2005-02-15)
Freund C; Schmidt-Ullrich R; Baurand A; Dunger S; Schneider W; Loser P; El-Jamali A; Dietz R; Scheidereit C; Bergmann MW
Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo
Circulation 111: 2319-2325 (2005-01-01)
Salanova B; Choi M; Rolle S; Wellner M; Scheidereit C; Luft FC; Kettritz R
The effect of fever-like temperatures on neutrophil signaling
FASEB Journal 19: 816-818 (2005-01-01)
Mathas S; Joehrens K; Joos S; Lietz A; Hummel F; Janz M; Jundt F; Anagnostopoulos I; Bommert K; Lichter P; Stein H; Scheidereit C; Doerken B
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas
Blood 106: 4287-4293 (2005-08-25)
Krappmann D; Scheidereit C
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways
EMBO Reports 6: 321-326 (2005-01-01)
Mehrhof FB; Schmidt-Ullrich R; Dietz R; Scheidereit C
Regulation of vascular smooth muscle cell proliferation. Role of NF-kappaB revisited
Circulation Research 96: 958-964 (2005-01-01)
2004
Scharschmidt E; Wegener E; Heissmeyer V; Rao A; Krappmann D
Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappaB signaling
Molecular and Cellular Biology 24: 3860-3873 (2004-05-01)
El Jamali A; Freund C; Rechner C; Scheidereit C; Dietz R; Bergmann MW
Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta
FASEB Journal 18: 1096-1098 (2004-01-01)
Broemer M; Krappmann D; Scheidereit C
Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation
Oncogene 23: 5378-5386 (2004-07-08)
Ohazama A; Hu YL; Schmidt-Ullrich R; Cao YX; Scheidereit C; Karin M; Sharpe PT
A dual role for lkkalpha in tooth development
Developmental Cell 6: 219-227 (2004-01-01)
Krappmann D; Wegener E; Sunami Y; Esen M; Thiel A; Mordmueller B; Scheidereit C
The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1
Molecular and Cellular Biology 24: 6488-6500 (2004-07-01)
2003
Mordmueller B; Krappmann D; Esen M; Wegener E; Scheidereit C
Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism
EMBO Reports 4: 82-87 (2003-01-01)
Scheidereit C
The pathogenetic significance of deregulated signal transduction pathways in Hodgkin's disease: the NF-kappaB-AP-1 network
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87: 79-89 (2003-01-01)
Mathas S; Lietz A; Janz M; Hinz M; Jundt F; Scheidereit C; Bommert K; Doerken B
Inhibition of NF-kappa B essentially contributes to arsenic-induced apoptosis
Blood 102: 1028-1034 (2003-01-01)
Choi M; Rolle S; Wellner M; Cardoso MC; Scheidereit C; Luft FC; Kettritz R
Inhibition of NF-kappa B by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis
Blood 102: 2259-2267 (2003-01-01)
Tegethoff S; Behlke J; Scheidereit C
Tetrameric oligomerization of I kappa B kinase gamma (IKK gamma) is obligatory for IKK complex activity and NF-kappa B activation
Molecular and Cellular Biology 23: 2029-2041 (2003-01-01)
2002
Hoepken UE; Foss HD; Meyer D; Hinz M; Leder K; Stein H; Lipp M
Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs
Blood 99: 1109-1116 (2002-01-01)
Mori N; Fujii M; Hinz M; Nakayama K; Yamada Y; Ikeda S; Yamasaki Y; Kashanchi F; Tanaka Y; Tomonaga M; Yamamoto N
Activation of cyclin D1 and D2 promoters by human T-cell leukemia virus type I tax protein is associated with IL-2-independent growth of T cells
International Journal of Cancer 99: 378-385 (2002-01-01)
Jundt F; Kley K; Anagnostopoulos I; Schulze-Probsting K; Greiner A; Mathas S; Scheidereit C; Wirth T; Stein H; Doerken B
Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease
Blood 99: 3060-3062 (2002-04-15)
Hawkes NA; Otero G; Winkler GS; Marshall N; Dahmus ME; Krappmann D; Scheidereit C; Thomas CL; Schiavo G; Erdjument-Bromage H; Tempst P; Svejstrup JQ
Purification and characterization of the human Elongator complex
Journal of Biological Chemistry 277: 3047-3052 (2002-01-01)
Hinz M; Lemke P; Anagnostopoulos I; Hacker C; Krappmann D; Mathas S; Doerken B; Zenke M; Stein H; Scheidereit C
Nuclear factor [kappa]B-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity
Journal of Experimental Medicine 196 (5): 605-617 (2002-09-02)
Mathas S; Hinz M; Anagnostopoulos L; Krappmann D; Lietz A; Jundt F; Bommert K; Mechta-Grigoriou F; Stein H; Doerken B; Scheidereit C
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B
EMBO Journal 21 (15): 4104-4113 (2002-08-01)
2001
Hinz M; Loeser P; Mathas S; Krappmann D; Doerken B; Scheidereit C
Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
Blood 97: 2798-2807 (2001-01-01)
Wuchter C; Krappmann D; Cai Z; Ruppert V; Scheidereit C; Doerken B; Ludwig WD; Karawajew L
In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappaB activity
Leukemia 15: 921-928 (2001-01-01)
Mueller DN; Heissmeyer V; Dechend R; Hampich F; Park JK; Fiebeler A; Shagdarsuren E; Theuer J; Elger M; Pilz B; Breu V; Schroer K; Ganten D; Dietz R; Haller H; Scheidereit C; Luft FC
Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage
FASEB Journal 15: 1822-1824 (2001-01-01)
Mehrhof FB; Mueller FU; Bergmann MW; Li PF; Wang YB; Schmitz W; Dietz R; von Harsdorf R
In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein
Circulation 104: 2088-2094 (2001-01-01)
Schmidt-Ullrich R; Aebischer T; Huelsken J; Birchmeier W; Klemm U; Scheidereit C
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices
Development 128: 3843-3853 (2001-01-01)
Slaugenhaupt SA; Blumenfeld A; Gill SP; Leyne M; Mull J; Cuajungco MP; Liebert CB; Chadwick B; Idelson M; Reznik L; Robbins CM; Makalowska I; Brownstein MJ; Krappmann D; Scheidereit C; Maayan C; Axelrod FB; Gusella JF
Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia
American Journal of Human Genetics 68: 598-605 (2001-01-01)
Holtmann H; Enninga J; Kalble S; Thiefes A; Dorrie A; Broemer M; Winzen R; Wilhelm A; Ninomiya-Tsuji J; Matsumoto K; Resch K; Kracht M
The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation
Journal of Biological Chemistry 276: 3508-3516 (2001-02-02)
Heissmeyer V; Krappmann D; Hatada EN; Scheidereit C
Shared pathways of IkappaB kinase-induced SCF betaTrCP-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and I kappa B alpha
Molecular and Cellular Biology 21: 1024-1035 (2001-01-01)
Kun JF; Mordmueller B; Perkins DJ; May J; Mercereau-Puijalon O; Alpers M; Weinberg JB; Kremsner PG
Nitric oxide synthase 2Lambarene (G-954C), increased nitric oxide production, and protection against malaria
Journal of Infectious Diseases 184: 330-336 (2001-01-01)
Krappmann D; Patke A; Heissmeyer V; Scheidereit C
B-cell receptor- and phorbol ester-induced NF-kappa B and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C's
Molecular and Cellular Biology 21: 6640-6650 (2001-01-01)
2000
Jueliger S; Luckner D; Mordmueller B; May J; Weierich A; Lell B; Luty A; Kremsner PG; Kun JF
Promoter variants of the human mannose-binding lectin gene show different binding
Biochemical and Biophysical Research Communications 275: 617-622 (2000-08-28)
Lange K; Kleuser B; Gysler A; Bader M; Maia C; Scheidereit C; Korting HC; Schaefer-Korting M
Cutaneous inflammation and proliferation in vitro: Differential effects and mode of action of topical glucocorticoids
Skin Pharmacology and Applied Skin Physiology 13: 93-103 (2000-03-01)
Kordes U; Krappmann D; Heissmeyer V; Ludwig WD; Scheidereit C
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells
Leukemia 14 (3): 399-402 (2000-03)
Feuillard J; Memet S; Goudeau B; Lilienbaum A; Schmidt-Ullrich R; Raphael M; Israel A
In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kappaB/Rel complexes
International Immunology 12 (5): 613-621 (2000-05)
Mathas S; Rickers A; Bommert K; Doerken B; Mapara MY
Anti-CD20-and B-cell receptor-mediated apoptosis: Evidence for shared intracellular signaling pathways
Cancer Research 60: 7170-7176 (2000-01-01)
Krappmann D; Hatada EN; Tegethoff S; Li J; Klippel A; Giesel K; Baeuerle A; Scheidereit C
The IkappaB kinase (IKK) complex is tripartiteand contains IKKgamma but not IKAP as a regular component
Journal of Biological Chemistry 275: 29779-29787 (2000-01-01)
Hatada EN; Chen-Kiang S; Scheidereit C
Interaction and functional interference of C/EBPbeta with octamer factors in immunoglobulin gene transcription
European Journal of Immunology 30: 174-184 (2000-01-01)
Hatada EN; Krappmann D; Scheidereit C
NF-kappaB and the innate immune response
Current Opinion in Immunology 12: 52-58 (2000-02-01)
Hehner SP; Hofmann TG; Ushmorov A; Dienz O; Leung IWL; Lassam N; Scheidereit C; Droege W; Schmitz ML
Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex
Molecular and Cellular Biology 20: 2556-2568 (2000-04-01)
1999
Emmerich F; Meiser M; Hummel M; Demel G; Foss HD; Jundt F; Mathas S; Krappmann D; Scheidereit C; Stein H; Doerken B
Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells
Blood 94: 3129-3134 (1999-11-01)
von Harsdorf R; Hauck L; Mehrhof F; Wegenka U; Cardoso MC; Dietz R
E2F-1 overexpression in cardiomyocytes induces downregulation of p21CIP1 and p27KIP1 and release of active cyclin-dependent kinases in the presence of insulin-like growth factor I
Circulation Research 85: 128-136 (1999-07-23)
Dechend R; Maass M; Gieffers J; Dietz R; Scheidereit C; Leutz A; Gulba DC
Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression - A potential link to accelerated arteriosclerosis
Circulation 100: 1369-1373 (1999-09-28)
Hinz M; Krappmann D; Eichten A; Heder A; Scheidereit C; Strauss M
NF-kappaB function in growth control: Regulation of cyclin D1 expression and G(0)G(1)-to-S-Phase transition
Molecular and Cellular Biology 19: 2690-2698 (1999-04-01)
Heissmeyer V; Krappmann D; Wulczyn FG; Scheidereit C
NF-kappaB p105 is a target of I kappaB kinases and controls signal induction of Bcl-3-p50 complexes
EMBO Journal 18: 4766-4778 (1999-09-01)
Krappmann D; Emmerich F; Kordes U; Scharschmidt E; Doerken B; Scheidereit C
Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells
Oncogene 18: 943-953 (1999-01-28)
Dechend R; Hirano F; Lehmann K; Heissmeyer V; Ansieau S; Wulczyn FG; Scheidereit C; Leutz A
The Bcl-3 oncoprotein acts as a bridging factor between NF-kappa B/Rel and nuclear co-regulators
Oncogene 18: 3316-3323 (1999-06-03)
1998
Hirano F; Tanaka H; Hirano Y; Hiramoto M; Handa H; Makino I; Scheidereit C
Functional interference of Sp1 and NF-kappaB through the same DNA binding site
Molecular and Cellular Biology 18 (3): 1266-1274 (1998-03)
Wulczyn FG; Krappmann D; Scheidereit C
Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53
Nucleic Acids Research 26 (7): 1724-1730 (1998-04-01)
Scheidereit C
Signal transduction - Docking IkappaB kinases
Nature 395: 225-226 (1998-09-17)
Hirano F; Chung MR; Tanaka H; Maruyama N; Makino I; Moore DD; Scheidereit C
Alternative splicing variants of IkappaBbeta establish differential NF-kappaB signal responsiveness in human cells
Molecular and Cellular Biology 18 (5): 2596-2607 (1998-05)
Mordmueller B; Kremsner PG
Hyperparasitemia and blood exchange transfusion for treatment of children with falciparum malaria
Clinical Infectious Diseases 26: 850-852 (1998-04-01)
Mordmueller B; Turrini F; Long H; Kremsner PG; Arese P
Neutrophils and monocytes from subjects with the Mediterranean G6PD variant: effect of Plasmodium falciparum hemozoin on G6PD activity, oxidative burst and cytokine production
European Cytokine Network 9: 239-245 (1998-09-01)
Hirano F; Tanaka H; Miura T; Hirano Y; Okamoto K; Makino Y; Makino I
Inhibition of NF-kappaB-dependent transcription of human immunodeficiency virus 1 promoter by a phosphodiester compound of vitamin C and vitamin E, EPC-K1
Immunopharmacology 39: 31-38 (1998-03-01)
Kun JF; Mordmueller B; Lell B; Lehman LG; Luckner D; Kremsner PG
Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria
Lancet 351 (9098): 265-266 (1998-01-24)
1997
Pelletier MR; Hatada EN; Scholz G; Scheidereit C
Efficient transcription of an immunoglobulin kappa promoter requires specific sequence elements overlapping with and downstream of the transcriptional start site
Nucleic Acids Research 25 (20): 3995-4003 (1997-10-15)
Ruppitsch W; Meisslitzer C; Weirichschwaiger H; Klocker H; Scheidereit C; Schweiger M; Hirschkauffmann M
The role of oxygen metabolism for the pathological phenotype of fanconi anemia
Human Genetics 99: 710-719 (1997-01-01)
Bargou RC; Emmerich F; Krappmann D; Bommert K; Mapara MY; Arnold W; Royer HD; Grinstein E; Greiner A; Scheidereit C; Doerken B
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells
Journal of Clinical Investigation 100 (12): 2961-2969 (1997-12-15)
Mordmueller BG; Metzger WG; Juillard P; Brinkman BM; Verweij CL; Grau GE; Kremsner PG
Tumor necrosis factor in Plasmodium falciparum malaria: high plasma level is associated with fever, but high production capacity is associated with rapid fever clearance
European Cytokine Network 8: 29-35 (1997-03-01)
1996
Krappmann D; Wulczyn FG; Scheidereit C
Different mechanisms control signal-induced degradation and basal turnover of the NF-kappab inhibitor ikappabalpha in vivo
EMBO Journal 15 (23): 6716-6726 (1996-12-02)
Scheidereit C
Transcription factors: important tools and targets for molecular medicine
Journal of Molecular Medicine 74: 707-709 (1996-01-01)
Wulczyn FG; Krappmann D; Scheidereit C
The NF-kappaB/Rel and IkappaB gene families: mediators of immune response and inflammation
Journal of Molecular Medicine 74: 749-769 (1996-01-01)
Bargou RC; Leng C; Krappmann D; Emmerich F; Mapara MY; Bommert K; Royer HD; Scheidereit C; Doerken B
High level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Sternberg cells
Blood 87 (10): 4340-4347 (1996-01-01)
Schmidt-Ullrich R; Memet S; Lilienbaum A; Feuillard J; Raphael M; Israel A
NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity
Development 122 (7): 2117-2128 (1996-07)
1994
Bouwmeester T; van Wijk I; Wedlich D; Pieler T
Functional aspects of B-Myb in early Xenopus development
Oncogene 9 (4): 1029-1038 (1994-04)
Naumann M; Scheidereit C
Activation of NF-kappaB in vivo is regulated by multiple phosphorylations
EMBO Journal 13 (19): 4597-4607 (1994-10-03)
Klocke B; Koester M; Hille S; Bouwmeester T; Boehm S; Pieler T; Knoechel W
The FAR domain defines a new Xenopous laevis zinc finger protein subfamily with specific RNA homopolymers binding activity
Biochimica et Biophysica Acta 1217: 81-89 (1994-01-01)
Franke S; Scholz G; Scheidereit C
Identification of novel ubiquitous and cell type-specific factors that specifically recognize immunoglobulin heavy and light chain promoters
Journal of Biological Chemistry 269 (31): 20075-20082 (1994-08-05)
Schafer U; Rausch O; Bouwmeester T; Pieler T
Sequence-specific recognition of a repetitive DNA element by a C2H2 zinc-finger protein in Xenopus
European Journal of Biochemistry 226: 567-576 (1994-12-01)
1993
Naumann M; Wulczyn FG; Scheidereit C
The NF-kappaB precursor p105 and the proto-oncogene product Bcl- 3 are I kappa B molecules and control nuclear translocation of NF-kappa B
EMBO Journal 12 (1): 213-222 (1993-01)
Hatada EN; Naumann M; Scheidereit C
Common structural constituents confer IkappaB activity to NF-kappaB p105 and IkappaB/MAD-3
EMBO Journal 12 (7): 2781-2788 (1993-07)
Naumann M; Nieters A; Hatada EN; Scheidereit C
NF-kappaB precursor p100 inhibits nuclear translocation and DNA binding of NF-kappaB/rel-factors
Oncogene 8 (8): 2275-2281 (1993-08-01)
1992
Kretzschmar M; Meisterernst M; Scheidereit C; Li G; Roeder RG
Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro
Genes & Development 6 (5): 761-774 (1992-05)
Hatada EN; Nieters A; Wulczyn FG; Naumann M; Meyer R; Nucifora G; McKeithan TW; Scheidereit C
The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappaB DNA binding
Proceedings of the National Academy of Sciences of the United States of America 89 (6): 2489-2493 (1992-01-01)
Wulczyn FG; Naumann M; Scheidereit C
Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappaB
Nature 358 (6387): 597-599 (1992-01-01)