Publications
2011
Lechner SG; Siemens J
Sensory transduction, the gateway to perception: mechanisms and pathology
EMBO Reports 12 (4): 292-295 (2011-04-01)
2010
Bohlen CJ; Priel A; Zhou S; King D; Siemens J; Julius D
A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain
Cell 141 (5): 834-845 (2010-05-28)
2007
Bautista DM; Siemens J; Glazer JM; Tsuruda PR; Basbaum AI; Stucky CL; Jordt SE; Julius D
The menthol receptor TRPM8 is the principal detector of environmental cold
Nature 448 (7150): 204-208 (2007-07-12)
McNamara CR; Mandel-Brehm J; Bautista DM; Siemens J; Deranian KL; Zhao M; Hayward NJ; Chong JA; Julius D; Moran MM; Fanger CM
TRPA1 mediates formalin-induced pain
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13525-13530 (2007-08-14)
Trevisani M; Siemens J; Materazzi S; Bautista DM; Nassini R; Campi B; Imamachi N; Andre E; Patacchini R; Cottrell GS; Gatti R; Basbaum AI; Bunnett NW; Julius D; Geppetti P
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13519-13524 (2007-08-14)
2006
Siemens J; Zhou S; Piskorowski R; Nikai T; Lumpkin EA; Basbaum AI; King D; Julius D
Spider toxins activate the capsaicin receptor to produce inflammatory pain
Nature 444 (7116): 208-212 (2006-11-09)
2004
Soellner C; Rauch GJ; Siemens J; Geisler R; Schuster SC; Mueller U; Nicolson T
Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells
Nature 428 (6986): 955-959 (2004-04-29)
Siemens J; Lillo C; Dumont RA; Reynolds A; Williams DS; Gillespie PG; Mueller U
Cadherin 23 is a component of the tip link in hair-cell stereocilia
Nature 428 (6986): 950-955 (2004-04-29)
2002
Siemens J; Kazmierczak P; Reynolds A; Sticker M; Littlewood-Evans A; Mueller U
The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions
Proceedings of the National Academy of Sciences of the United States of America 99 (23): 14946-14951 (2002-11-12)
2001
Siemens J; Littlewood-Evans A; Mueller U
The sound of silence - diseases that cause deafness and disequilibrium
B.I.F. Futura 16: 222-228 (2001)
Siemens J; Littlewood-Evans A; Senften M; Mueller U
Genes, deafness, and balance disorders
Gene Function and Disease 2 (2-3): 76-82 (2001-10-02)