Ausgewählte Publikationen



2017

Benary U.; Wolf E.; Wolf J.
Mathematical modelling of promoter occupancies in MYC-dependent gene regulation
Genomics and Computational Biology 3 (2): e54 (2017)



2016

Baum K.; Politi A.Z.; Kofahl B.; Steuer R.; Wolf J.
Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations
PLoS Computational Biology 12 (12): e1005298 (2016-12-27)



Lorenzin F.; Benary U.; Baluapuri A.; Walz S.; Jung L.A.; von Eyss B.; Kisker C.; Wolf J.; Eilers M.; Wolf E.
Different promoter affinities account for specificity in MYC-dependent gene regulation
eLife 5: e15161 (2016-07-27)



2015

Murakawa Y.; Hinz M.; Mothes J.; Schuetz A.; Uhl M.; Wyler E.; Yasuda T.; Mastrobuoni G.; Friedel C.C.; Doelken L.; Kempa S.; Schmidt-Supprian M.; Bluethgen N.; Backofen R.; Heinemann U.; Wolf J.; Scheidereit C.; Landthaler M.
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-{kappa}B pathway
Nature Communications 6: 7367 (2015-07-14)



Thongwichian R.; Kosten J.; Benary U.; Rose H.M.; Stuiver M.; Theillet F.X.; Dose A.; Koch B.; Yokoyama H.; Schwarzer D.; Wolf J.; Selenko P.
A multiplexed NMR-reporter approach to measure cellular kinase and phosphatase activities in real-time
Journal of the American Chemical Society 137 (20): 6468-6471 (2015-05-27)



Mothes J.; Busse D.; Kofahl B.; Wolf J.
Sources of dynamic variability in NF-{kappa}B signal transduction: a mechanistic model
BioEssays 37 (4): 452-462 (2015-04)



Benary U.; Kofahl B.; Hecht A.; Wolf J.
Mathematical modelling suggests differential impact of {beta}-TrCP paralogues on Wnt/{beta}-catenin signalling dynamics
FEBS Journal 282 (6): 1080-1096 (2015-03)



2014

Yilmaz Z.B.; Kofahl B.; Beaudette P.; Baum K.; Ipenberg I.; Weih F.; Wolf J.; Dittmar G.; Scheidereit C.
Quantitative dissection and modeling of the NF-{kappa}B p100-p105 module reveals interdependent precursor proteolysis
Cell Reports 9 (5): 1756-1769 (2014-12-11)



2013

Schwanhaeusser B.; Wolf J.; Selbach M.; Busse D.
Synthesis and degradation jointly determine the responsiveness of the cellular proteome
BioEssays 35 (7): 597-601 (2013-07)



Hertel S.; Brettschneider C.; Axmann I.M.
Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock
PLoS Computational Biology 9 (3): e1002966 (2013-03-14)



Benary U.; Kofahl B.; Hecht A.; Wolf J.
Modeling Wnt/beta-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions
Frontiers in Physiology 4: 21 (2013-02-25)



2012

Schmidt V.; Baum K.; Lao A.; Rateitschak K.; Schmitz Y.; Teichmann A.; Wiesner B.; Petersen C.M.; Nykjaer A.; Wolf J.; Wolkenhauer O.; Willnow T.E.
Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease
EMBO Journal 31 (1): 187-200 (2012-01-04)



2011

Schwanhaeusser B.; Busse D.; Li N.; Dittmar G.; Schuchhardt J.; Wolf J.; Chen W.; Selbach M.
Global quantification of mammalian gene expression control
Nature 473 (7347): 337-342 (2011-05-19)



Schuetze J.; Mair T.; Hauser M.J.; Falcke M.; Wolf J.
Metabolic synchronization by traveling waves in yeast cell layers
Biophysical Journal 100 (4): 809-813 (2011-02-16)



2010

Kofahl B.; Wolf J.
Mathematical modelling of Wnt/beta-catenin signalling
Biochemical Society Transactions 38 (5): 1281-1285 (2010-10-01)



Schuetze J.; Wolf J.
Spatio-temporal dynamics of glycolysis in cell layers. A mathematical model
Biosystems 99 (2): 104-108 (2010-02)



2009

Rueder C.; Hoepken U.E.; Wolf J.; Mittruecker H.W.; Engels B.; Erdmann B.; Wollenzin S.; Uckert W.; Doerken B.; Rehm A.
The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells
Journal of Clinical Investigation 119 (8): 2184-2203 (2009-08)



2007

Wolf J.; Dronov S.; Tobin F.; Goryanin I.
The impact of the regulatory design on the response of epidermal growth factor receptor-mediated signal transduction towards oncogenic mutations
FEBS Journal 274 (21): 5505-5517 (2007-11)



2005

Wolf J.; Becker-Weimann S.; Heinrich R.
Analysing the robustness of cellular rhythms
Systems Biology 2 (1): 35-41 (2005-03)



2004

Becker-Weimann S.; Wolf J.; Herzel H.; Kramer A.
Modeling feedback loops of the Mammalian circadian oscillator
Biophysical Journal 87 (5): 3023-3034 (2004-11)



2003

Ruoff P.; Christensen M.K.; Wolf J.; Heinrich R.
Temperature dependency and temperature compensation in a model of yeast glycolytic oscillations
Biophysical Chemistry 106 (2): 179-192 (2003-11-01)



2001

Wolf J.; Sohn H.; Heinrich R.; Kuriyama H.
Mathematical analysis of a mechanism for autonomous metabolic oscillations in continuous culture of Saccharomyces cerevisiae
FEBS Letters 499 (3): 230-234 (2001-06-22)



2000

Wolf J.; Passarge J.; Somsen O.J.; Snoep J.L.; Heinrich R.; Westerhoff H.V.
Transduction of intracellular and intercellular dynamics in yeast glycolytic oscillations
Biophysical Journal 78 (3): 1145-1153 (2000-03)



Wolf J.; Heinrich R.
Effect of cellular interaction on glycolytic oscillations in yeast: a theoretical investigation
Biochemical Journal 345 (Pt 2): 321-334 (2000-01-15)



1997

Wolf J.; Heinrich R.
Dynamics of two-component biochemical systems in interacting cells; synchronization and desynchronization of oscillations and multiple steady states
Bio Systems 43 (1): 1-24 (1997-05)