Jadasz J.J.; Tepe L.; Beyer F.; Samper Agrelo I.; Akkermann R.; Spitzhorn L.S.; Silva M.E.; Oreffo R.O.C.; Hartung H.P.; Prigione A.; Rivera F.J.; Adjaye J.; Kuery P.
Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis
Glia 66 (1): 145-160 (2018-01)


Scior A.; Buntru A.; Arnsburg K.; Ast A.; Iburg M.; Juenemann K.; Pigazzini M.L.; Mlody B.; Puchkov D.; Priller J.; Wanker E.E.; Prigione A.; Kirstein J.
Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex
EMBO Journal : e201797212 (2017-12-06)

Arslan A.D.; Sassano A.; Saleiro D.; Lisowski P.; Kosciuczuk E.M.; Fischietti M.; Eckerdt F.; Fish E.N.; Platanias L.C.
Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma
Oncogene 36 (43): 6006-6019 (2017-10-26)

Mlody B.; Wruck W.; Martins S.; Sperling K.; Adjaye J.
Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants.
Scientific Reports 7 (1): 7516 (2017-08-08)

Inak G.; Lorenz C.; Lisowski P.; Zink A.; Mlody B.; Prigione A.
Concise review: Induced pluripotent stem cell-based drug discovery for mitochondrial disease
Stem Cells 35 (7): 1655-1662 (2017-07)

Yumlu S.; Stumm J.; Bashir S.; Dreyer A.K.; Lisowski P.; Danner E.; Kuehn R.
Gene editing and clonal isolation of human induced pluripotent stem cells using CRISPR/Cas9
Methods 121-122: 29-44 (2017-05-15)

Lorenz C.; Lesimple P.; Bukowiecki R.; Zink A.; Inak G.; Mlody B.; Singh M.; Semtner M.; Mah N.; Aure K.; Leong M.; Zabiegalov O.; Lyras E.M.; Pfiffer V.; Fauler B.; Eichhorst J.; Wiesner B.; Huebner N.; Priller J.; Mielke T.; Meierhofer D.; Izsvak Z.; Meier J.C.; Bouillaud F.; Adjaye J.; Schuelke M.; Wanker E.E.; Lombes A.; Prigione A.
Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders
Cell Stem Cell 20 (5): 659-674.e9 (2017-05-04)

Voepel T.; Bravo-Rodriguez K.; Mittal S.; Vachharajani S.; Gnutt D.; Sharma A.; Steinhof A.; Fatoba O.; Ellrichmann G.; Nshanian M.; Heid C.; Loo J.A.; Klaerner F.-G.; Schrader T.; Bitan G.; Wanker E.E.; Ebbinghaus S.; Sanchez-Garcia E.
Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01
Journal of the American Chemical Society 139 (16): 5640-5643 (2017-04-26)

Sin O.; de Jong T.; Mata-Cabana A.; Kudron M.; Zaini M.A.; Aprile F.A.; Seinstra R.I.; Stroo E.; Prins R.W.; Martineau C.N.; Wang H.H.; Hogewerf Wytse; Steinhof A.; Wanker E.E.; Vendruscolo M.; Calkhoven C.F.; Reinke V.; Guryev V.; Nollen E.A.A.
Identification of an RNA polymerase III regulator linked to disease-associated protein aggregation
Molecular Cell 65 (6): 1096-1108.e6 (2017-03-16)

Rodriguez Camargo D.C.; Tripsianes K.; Buday K.; Franko A.; Goebl C.; Hartlmueller C.; Sarkar R.; Aichler M.; Mettenleiter G.; Schulz M.; Boeddrich A.; Erck C.; Martens H.; Walch A.K.; Madl T.; Wanker E.E.; Conrad M.; de Angelis M.H.; Reif B.
The redox environment triggers conformational changes and aggregation of hIAPP in type II diabetes
Scientific Reports 7: 44041 (2017-03-13)

Grzybek M.; Golonko A.; Walczak M.; Lisowski P.
Epigenetics of cell fate reprogramming and its implications for neurological disorders modelling
Neurobiology of Disease 99: 84-120 (2017-03)

Andrich K.; Hegenbart U.; Kimmich C.; Kedia N.; Bergen H.R.; Schoenland S.; Wanker E.E.; Bieschke J.
Aggregation of full length immunoglobulin light chains from AL amyloidosis patients is remodeled by epigallocatechin-3-gallate
Journal of Biological Chemistry 292 (6): 2328-2344 (2017-02-10)

Goerke S.; Milde K.S.; Bukowiecki R.; Kunz P.; Klika K.D.; Wiglenda T.; Mogk A.; Wanker E.E.; Bukau B.; Ladd M.E.; Bachert P.; Zaiss M.
Aggregation-induced changes in the chemical exchange saturation transfer (CEST) signals of proteins
NMR in Biomedicine 30 (1): e3665 (2017-01)


Schottmann G.; Sarpong A.; Lorenz C.; Weinhold N.; Gill E.; Teschner L.; Ferdinandusse S.; Wanders R.J.A.; Prigione A.; Schuelke M.
A movement disorder with dystonia and ataxia caused by a mutation in the HIBCH gene
Movement Disorders 31 (11): 1733-1739 (2016-11)

Lessard-Beaudoin M.; Laroche M.; Loudghi A.; Demers M.J.; Denault J.B.; Grenier G.; Riechers S.P.; Wanker E.E.; Graham R.K.
Organ-specific alteration in caspase expression and STK3 proteolysis during the aging process
Neurobiology of Aging 47: 50-62 (2016-11)

Lessard-Beaudoin M.; Laroche M.; Demers M.J.; Duclos C.; Denault J.B.; Grenier G.; Riechers S.P.; Wanker E.E.; Graham R.K.
Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice
Biogerontology 17 (5): 817-828 (2016-11)

Arumughan A.; Roske Y.; Barth C.; Lleras Forero L.; Bravo-Rodriguez K.; Redel Al.; Kostova S.; McShane E.; Opitz R.; Faelber K.; Rau K.; Mielke T.; Daumke O.; Selbach M.; Sanchez-Garcia E.; Rocks O.; Panakova D.; Heinemann U.; Wanker E.E.
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers
Nature Communications 7: 13047 (2016-10-20)

Mlody B.; Prigione A.
A glycolytic solution for pluripotent stem cells
Cell Stem Cell 19 (4): 419-420 (2016-10-06)

Hempel P.; Heinig B.; Jerosch C.; Decius I.; Karczewski P.; Kassner U.; Kunze R.; Steinhagen-Thiessen E.; Bimmler M.
Immunoadsorption of agonistic autoantibodies against {alpha}1-adrenergic receptors in patients with mild to moderate dementia
Therapeutic Apheresis and Dialysis 20 (5): 523-529 (2016-10)

Jin S.; Kedia N.; Illes-Toth E.; Haralampiev I.; Prisner S.; Herrmann A.; Wanker E.E.; Bieschke J.
Amyloid-{beta}(1-42) aggregation initiates its cellular uptake and cytotoxicity
Journal of Biological Chemistry 291 (37): 19590-19606 (2016-09-09)

Lorenz C.; Prigione A.
Aging vs. rejuvenation: reprogramming to iPSCs does not turn back the clock for somatic mitochondrial DNA mutations
Stem Cell Investigation 3: 43 (2016-09)

Mazza A.; Klockmeier K.; Wanker E.; Sharan R.
An integer programming framework for inferring disease complexes from network data
Bioinformatics 32 (12): i271-i277 (2016-06-15)

Zografos L.; Tang J.; Hesse F.; Wanker E.E.; Li K.W.; Smit A.B.; Davies R.W.; Armstrong J.D.
Functional characterisation of human synaptic genes expressed in the Drosophila brain
Biology Open 5 (5): 662-667 (2016-05-15)

Buntru A.; Trepte P.; Klockmeier K.; Schnoegl S.; Wanker E.E.
Current approaches toward quantitative mapping of the interactome
Frontiers in Genetics 7: 74 (2016-05-04)

Riechers S.P.; Butland S.; Deng Y.; Skotte N.; Ehrnhoefer D.E.; Russ J.; Laine J.; Laroche M.; Pouladi M.A.; Wanker E.E.; Hayden M.R.; Graham R.K.
Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD
Human Molecular Genetics 25 (8): 1600-1618 (2016-05)

Klein A.N.; Ziehm T.; Tusche M.; Buitenhuis J.; Bartnik D.; Boeddrich A.; Wiglenda T.; Wanker E.; Funke S.A.; Brener O.; Gremer L.; Kutzsche J.; Willbold D.
Optimization of the All-D peptide D3 for A{beta} oligomer elimination
PLoS ONE 11 (4): e0153035 (2016-04-22)

Prigione A.
A mitochondrial view of cell fate
Seminars in Cell & Developmental Biology 52: 66-67 (2016-04)

Mlody B.; Lorenz C.; Inak G.; Prigione A.
Energy metabolism in neuronal/glial induction and iPSC-based modeling of brain disorders
Seminars in Cell & Developmental Biology 52: 102-109 (2016-04)

Shcheslavskiy V.I.; Neubauer A.; Bukowiecki R.; Dinter F.; Becker W.
Combined fluorescence and phosphorescence lifetime imaging
Applied Physics Letters 108 (9): 091111 (2016-03-03)

Jung B.; Messias A.C.; Schorpp K.; Geerlof A.; Schneider G.; Saur D.; Hadian K.; Sattler M.; Wanker E.E.; Hasenoeder S.; Lickert H.
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation
Scientific Reports 6: 22540 (2016-03-02)

Wang J.; Singh M.; Sun C.; Besser D.; Prigione A.; Ivics Z.; Hurst L.D.; Izsvak Z.
Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression
Nature Protocols 11 (2): 327-346 (2016-02)


Rohwer N.; Bindel F.; Grimm C.; Lin S.J.; Wappler J.; Klinger B.; Bluethgen N.; Du Bois I.; Schmeck B.; Lehrach H.; de Graauw M.; Goncalves E.; Saez-Rodriguez J.; Tan P.; Grabsch H.I.; Prigione A.; Kempa S.; Cramer T.
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A
Oncotarget 7 (6): 6693-6710 (2015-12-29)

Trepte P.; Buntru A.; Klockmeier K.; Willmore L.; Arumughan A.; Secker C.; Zenkner M.; Brusendorf L.; Rau K.; Redel A.; Wanker E.E.
DULIP: A dual luminescence-based co-immunoprecipitation assay for interactome mapping in mammalian cells
Journal of Molecular Biology 427 (21): 3375-3388 (2015-10-23)

Bender J.; Engeholm M.; Ederer M.S.; Breu J.; Moller T.C.; Michalakis S.; Rasko T.; Wanker E.E.; Biel M.; Martinez K.L.; Wurst W.; Deussing J.M.
Corticotropin-releasing hormone receptor type 1 (CRHR1) clustering with MAGUKs is mediated via its C-terminal PDZ binding motif
PLoS ONE 10 (9): e0136768 (2015-09-09)

Fossati G.; Morini R.; Corradini I.; Antonucci F.; Trepte P.; Edry E.; Sharma V.; Papale A.; Pozzi D.; Defilippi P.; Meier J.C.; Brambilla R.; Turco E.; Rosenblum K.; Wanker E.E.; Ziv N.E.; Menna E.; Matteoli M.
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis
Cell Death and Differentiation 22 (9): 1425-1436 (2015-09)

Stincone A.; Prigione A.; Cramer T.; Wamelink M.M.C.; Campbell K.; Cheung E.; Olin-Sandoval V.; Gruening N.M.; Krueger A.; Tauqeer Alam M.; Keller M.A.; Breitenbach M.; Brindle K.M.; Rabinowitz J.D.; Ralser M.
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
Biological Reviews 90 (3): 927-963 (2015-08)

Hosp F.; Vossfeldt H.; Heinig M.; Vasiljevic D.; Arumughan A.; Wyler E.; Landthaler M.; Hubner N.; Wanker E.E.; Lannfelt L.; Ingelsson M.; Lalowski M.; Voigt A.; Selbach M.
Quantitative interaction proteomics of neurodegenerative disease proteins
Cell Reports 11 (7): 1134-1146 (2015-05-19)

Prigione A.; Ruiz-Perez M.V.; Bukowiecki R.; Adjaye J.
Metabolic restructuring and cell fate conversion
Cellular and Molecular Life Sciences 72 (9): 1759-1777 (2015-05-01)

Stroedicke M.; Bounab Y.; Strempel N.; Klockmeier K.; Yigit S.; Friedrich R.P.; Chaurasia G.; Li S.; Hesse F.; Riechers S.P.; Russ J.; Nicoletti C.; Boeddrich A.; Wiglenda T.; Haenig C.; Schnoegl S.; Fournier D.; Graham R.K.; Hayden M.R.; Sigrist S.; Bates G.P.; Priller J.; Andrade-Navarro M.A.; Futschik M.E.; Wanker E.E.
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity
Genome Research 25 (5): 701-713 (2015-05)

Saleiro D.; Mehrotra S.; Kroczynska B.; Beauchamp E.M.; Lisowski P.; Majchrzak-Kita B.; Bhagat T.D.; Stein B.L.; McMahon B.; Altman J.K.; Kosciuczuk E.M.; Baker D.P.; Jie C.; Jafari N.; Thompson C.B.; Levine R.L.; Fish E.N.; Verma A.K.; Platanias L.C.
Central role of ULK1 in type I interferon signaling
Cell Reports 11 (4): 605-617 (2015-04-28)

Gao M.; Estel K.; Seeliger J.; Friedrich R.P.; Dogan S.; Wanker E.E.; Winter R.; Ebbinghaus S.
Modulation of human IAPP fibrillation: cosolutes, crowders and chaperones
Physical Chemistry Chemical Physics 17 (13): 8338-8348 (2015-04-07)

Ito H.; Shiwaku H.; Yoshida C.; Homma H.; Luo H.; Chen X.; Fujita K.; Musante L.; Fischer U.; Frints S.G.M.; Romano C.; Ikeuchi Y.; Shimamura T.; Imoto S.; Miyano S.; Muramatsu S.I.; Kawauchi T.; Hoshino M.; Sudol M.; Arumughan A.; Wanker E.E.; Rich T.; Schwartz C.; Matsuzaki F.; Bonni A.; Kalscheuer V.M.; Okazawa H.
In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells
Molecular Psychiatry 20 (4): 459-471 (2015-04)

Mroz R.M.; Lisowski P.; Tycinska A.; Bierla J.; Trzeciak P.Z.; Minarowski L.; Milewski R.; Lisowska A.; Boros P.; Sobkowicz B.; Duszewska A.M.; Chyczewska E.; Musial W.J.; MacNee W.
Anti-inflammatory effects of atorvastatin treatment in chronic obstructive pulmonary disease. A controlled pilot study
Journal of Physiology and Pharmacology 66 (1): 111-128 (2015-02)

Prigione A.
Induced pluripotent stem cells (iPSCs) for modeling mitochondrial DNA disorders
Methods in Molecular Biology 1265: 349-356 (2015-01-06)

Wobst H.J.; Sharma A.; Diamond M.I.; Wanker E.E.; Bieschke J.
The green tea polyphenol (-)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios
FEBS Letters 589 (1): 77-83 (2015-01-02)

Pfiffer V.; Prigione A.
Assessing the bioenergetic profile of human pluripotent stem cells
Methods in Molecular Biology 1264: 279-288 (2015)

Andrich K.; Bieschke J.
The effect of (-)-Epigallo-catechin-(3)-gallate on amyloidogenic proteins suggests a common mechanism
Advances in Experimental Medicine and Biology 863: 139-161 (2015)


Wang J.; Xie G.; Singh M.; Ghanbarian A.T.; Rasko T.; Szvetnik A.; Cai H.; Besser D.; Prigione A.; Fuchs N.V.; Schumann G.G.; Chen W.; Lorincz M.C.; Ivics Z.; Hurst L.D.; Izsvak Z.
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
Nature 516 (7531): 405-409 (2014-12-18)

Stankiewicz A.M.; Goscik J.; Swiergiel A.H.; Majewska A.; Wieczorek M.; Juszczak G.R.; Lisowski P.
Social stress increases expression of hemoglobin genes in mouse prefrontal cortex
BMC Neuroscience 15 (1): 130 (2014-12-04)

Schweiger S.; Dorn S.; Fuchs M.; Koehler A.; Matthes F.; Mueller E.C.; Wanker E.; Schneider R.; Krauss S.
The E3-ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu
Journal of Biological Chemistry 289 (46): 31805-31817 (2014-11-14)

Dernedde J.; Weise C.; Mueller E.C.; Hagiwara A.; Bachmann S.; Suzuki M.; Reutter W.; Tauber R.; Scherer H.
Cupulin is a zona pellucida-like domain protein and major component of the cupula from the inner ear
PLoS ONE 9 (11): e111917 (2014-11-04)

Otte D.M.; Rasko T.; Wang M.; Dreiseidler M.; Drews E.; Schrage H.; Wojtalla A.; Hoehfeld J.; Wanker E.; Zimmer A.
Identification of the mitochondrial MSRB2 as a binding partner of LG72
Cellular and Molecular Neurobiology 34 (8): 1123-1130 (2014-11)

Suratanee A.; Schaefer M.H.; Betts M.J.; Soons Z.; Mannsperger H.; Harder N.; Oswald M.; Gipp M.; Ramminger E.; Marcus G.; Maenner R.; Rohr K.; Wanker E.; Russell R.B.; Andrade-Navarro M.A.; Eils R.; Koenig R.
Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen
PLoS Computational Biology 10 (9): e1003814 (2014-09-25)

Kayatekin C.; Matlack K.E.S.; Hesse W.R.; Guan Y.; Chakrabortee S.; Russ J.; Wanker E.E.; Shah J.V.; Lindquist S.
Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1
Proceedings of the National Academy of Sciences of the United States of America 111 (33): 12085-12090 (2014-08-19)

Trepte P.; Strempel N.; Wanker E.E.
Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures
Essays in Biochemistry 56 (1): 167-180 (2014-08-18)

Butland S.L.; Sanders S.S.; Schmidt M.E.; Riechers S.P.; Lin D.T.S.; Martin D.D.O.; Vaid K.; Graham R.K.; Singaraja R.R.; Wanker E.E.; Conibear E.; Hayden M.R.
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of huntington disease
Human Molecular Genetics 23 (15): 4142-4160 (2014-08-01)

Janbein M.; Quader M.A.; Hoppner A.C.; Gruener I.; Wanker E.; Waelter S.; Kueppers E.; Grissmer S.; Jaeger H.
Evidence for the interaction of Endophilin A3 with endogenous K(Ca)2.3 channels in PC12 cells
Cellular Physiology and Biochemistry 34 (2): 474-490 (2014-07-30)

Wolfe K.J.; Ren H.Y.; Trepte P.; Cyr D.M.
Polyglutamine-rich suppressors of huntingtin toxicity act upstream of hsp70 and sti1 in spatial quality control of amyloid-like proteins
PLoS ONE 9 (5): e95914 (2014-05-14)

Dathe C.; Daigeler A.L.; Seifert W.; Jankowski V.; Mrowka R.; Kalis R.; Wanker E.; Mutig K.; Bachmann S.; Paliege A.
Annexin A2 mediates apical trafficking of renal Na(+)-K(+)-2Cl(-)-cotransporter
Journal of Biological Chemistry 289 (14): 9983-9997 (2014-04-04)

Prigione A.; Adjaye J.
A mitochondrial strategy for safeguarding the reprogrammed genome
Cell Regeneration 3 (1): 5 (2014-03-29)

Prigione A.; Rohwer N.; Hoffman S.; Mlody B.; Drews K.; Bukowiecki R.; Bluemlein K.; Wanker E.E.; Ralser M.; Cramer T.; Adjaye J.
HIF1{alpha} modulates reprogramming through early glycolytic shift and up-regulation of PDK1-3 and PKM2
Stem Cells 32 (2): 364-376 (2014-02)

Bukowiecki R.; Adjaye J.; Prigione A.
Mitochondrial function in pluripotent stem cells and cellular reprogramming
Gerontology 60 (2): 174-182 (2014-02)


Toh P.P.C.; Luo S.; Menzies F.M.; Rasko T.; Wanker E.E.; Rubinsztein D.C.
Myc inhibition impairs autophagosome formation
Human Molecular Genetics 22 (25): 5237-5248 (2013-12-20)

Wolfe K.J.; Ren H.Y.; Trepte P.; Cyr D.M.
The Hsp70/90 cochaperone, Sti1, suppresses proteotoxicity by regulating spatial quality control of amyloid-like proteins
Molecular Biology of the Cell 24 (23): 3588-3602 (2013-12)

Mielcarek M.; Landles C.; Weiss A.; Bradaia A.; Seredenina T.; Inuabasi L.; Osborne G.F.; Wadel K.; Touller C.; Butler R.; Robertson J.; Franklin S.A.; Smith D.L.; Park L.; Marks P.A.; Wanker E.E.; Olson E.N.; Luthi-Carter R.; van der Putten H.; Beaumont V.; Bates G.P.
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
PLoS Biology 11 (11): e1001717 (2013-11)

O'Rourke J.G.; Gareau J.R.; Ochaba J.; Song W.; Rasko T.; Reverter D.; Lee J.; Monteys A.M.; Pallos J.; Mee L.; Vashishtha M.; Apostol B.L.; Nicholson T.P.; Illes K.; Zhu Y.Z.; Dasso M.; Bates G.P.; Difiglia M.; Davidson B.; Wanker E.E.; Marsh J.L.; Lima C.D.; Steffan J.S.; Thompson L.M.
SUMO-2 and PIAS1 modulate insoluble mutant Huntingtin protein accumulation
Cell Reports 4 (2): 362-375 (2013-07-25)

Petrakis S.; Schaefer M.H.; Wanker E.E.; Andrade-Navarro M.A.
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners
BioEssays 35 (6): 503-507 (2013-06)

Kettner K.; Kuettner E.B.; Otto A.; Lilie H.; Golbik R.P.; Straeter N.; Kriegel T.M.
In vivo phosphorylation and in vitro autophosphorylation-inactivation of Kluyveromyces lactis hexokinase KlHxk1
Biochemical and Biophysical Research Communications 435 (2): 313-318 (2013-05-31)

Weimann M.; Grossmann A.; Woodsmith J.; Ozkan Z.; Birth P.; Meierhofer D.; Benlasfer N.; Valovka T.; Timmermann B.; Wanker E.E.; Sauer S.; Stelzl U.
A Y2H-seq approach defines the human protein methyltransferase interactome
Nature Methods 10 (4): 339-342 (2013-04)

Wallach T; Schellenberg K; Maier B; Kalathur R.K.; Porras P.; Wanker E.E.; Futschik M.E.; Kramer A.
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
PLoS Genetics 9 (3): e1003398 (2013-03)

Krauss S.; Griesche N.; Jastrzebska E.; Chen C.; Rutschow D.; Achmueller C.; Dorn S.; Boesch S.M.; Lalowski M.; Wanker E.; Schneider R.; Schweiger S.
Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex
Nature Communications 4: 1511 (2013-02-26)

Maehler A.; Mandel S.; Lorenz M.; Ruegg U.; Wanker E.E.; Boschmann M.; Paul F.
Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases
EPMA Journal 4 (1): 5 (2013-02-18)

Lorenzen N.; Wanker E.E.; Otzen D.
Inhibitors of amyloid and oligomer formation
Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties : 345-372 (2013-02-12)

Suter B.; Fontaine J.F.; Yildirimman R.; Rasko T.; Schaefer M.H.; Rasche A.; Porras P.; Vazquez-Alvarez B.M.; Russ J.; Rau K.; Foulle R.; Zenkner M.; Saar K.; Herwig R.; Andrade-Navarro M.A.; Wanker E.E.
Development and application of a DNA microarray-based yeast two-hybrid system
Nucleic Acids Research 41 (3): 1496-507 (2013-02-01)

Fujita K.; Nakamura Y.; Oka T.; Ito H.; Tamura T.; Tagawa K.; Sasabe T.; Katsuta A.; Motoki K.; Shiwaku H.; Sone M.; Yoshida C.; Katsuno M.; Eishi Y.; Murata M.; Taylor J.P.; Wanker E.E.; Kono K.; Tashiro S.; Sobue G.; La Spada A.R.; Okazawa H.
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases
Nature Communications 4: 1816 (2013)


Kristen A.V.; Lehrke S.; Buss S.; Mereles D.; Steen H.; Ehlermann P.; Hardt S.; Giannitsis E.; Schreiner R.; Haberkorn U.; Schnabel P.A.; Linke R.P.; Roecken C.; Wanker E.E.; Dengler T.J.; Altland K.; Katus H.A.
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report
Clinical Research in Cardiology 101 (10): 805-813 (2012-10)

Lopez Del Amo J.M.; Fink U.; Dasari M.; Grelle G.; Wanker E.E.; Bieschke J.; Reif B.
Structural properties of EGCG-induced, nontoxic Alzheimer's disease A{beta} oligomers
Journal of Molecular Biology 421 (4-5): 517-524 (2012-08-24)

Petrakis S.; Rasko T.; Russ J.; Friedrich R.P.; Stroedicke M.; Riechers S.P.; Muehlenberg K.; Moeller A.; Reinhardt A.; Vinayagam A.; Schaefer M.H.; Boutros M.; Tricoire H.; Andrade-Navarro M.A.; Wanker E.E.
Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1
PLoS Genetics 8 (8): e1002897 (2012-08-16)

Pankonien I.; Otto A.; Dascal N.; Morano I.; Haase H.
Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cav{beta}(2)
Biochemical and Biophysical Research Communications 421 (2): 184-189 (2012-05-04)

Schaefer M.H.; Wanker E.E.; Andrade-Navarro M.A.
Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks
Nucleic Acids Research 40 (10): 4273-4287 (2012-05-01)

Chua J.J.E.; Butkevich E.; Worseck J.M.; Kittelmann M.; Gronborg M.; Behrmann E.; Stelzl U.; Pavlos N.J.; Lalowski M.M.; Eimer S.; Wanker E.E.; Klopfenstein D.R.; Jahn R.
Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5862-5867 (2012-04-10)

von Eyss B.; Maaskola J.; Memczak S.; Moellmann K.; Schuetz A.; Loddenkemper C.; Tanh M.D.; Otto A.; Muegge K.; Heinemann U.; Rajewsky N.; Ziebold U.
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation
EMBO Journal 31 (4): 972-985 (2012-02-15)

Schaefer M.H.; Fontaine J.F.; Vinayagam A.; Porras P.; Wanker E.E.; Andrade-Navarro M.A.
HIPPIE: integrating protein interaction networks with experiment based quality scores
PLoS ONE 7 (2): e31826 (2012-02-14)

Sommer A.P.; Bieschke J.; Friedrich R.P.; Zhu D.; Wanker E.E.; Fecht H.J.; Mereles D.; Hunstein W.
670 nm laser light and EGCG complementarily reduce amyloid-{beta} aggregates in human neuroblastoma cells: basis for treatment of Alzheimer's disease?
Photomedicine and Laser Surgery 30 (1): 54-60 (2012-01-04)

Bieschke J.; Herbst M.; Wiglenda T.; Friedrich R.P.; Boeddrich A.; Schiele F.; Kleckers D.; Lopez Del Amo J.M.; Gruening B.A.; Wang Q.; Schmidt M.R.; Lurz R.; Anwyl R.; Schnoegl S.; Faendrich M.; Frank R.F.; Reif B.; Guenther S.; Walsh D.M.; Wanker E.E.
Small-molecule conversion of toxic oligomers to nontoxic {beta}-sheet-rich amyloid fibrils
Nature Chemical Biology 8 (1): 93-101 (2012-01)

Suter B.; Wanker E.E.
The investigation of binary PPIs with the classical yeast two-hybrid (Y2H) approach, Y2H variants, and other in vivo methods for PPI mapping
Methods in Molecular Biology 812: v-vi (2012)


Kunde S.A.; Musante L.; Grimme A.; Fischer U.; Mueller E.; Wanker E.E.; Kalscheuer V.M.
The X-chromosome linked intellectual disability protein PQBP1 is a component of neuronal RNA granules and regulates the appearance of stress granules
Human Molecular Genetics 20 (24): 4916-4931 (2011-12-15)

Grelle G.; Otto A.; Lorenz M.; Frank R.F.; Wanker E.E.; Bieschke J.
Black tea theaflavins inhibit formation of toxic amyloid-beta and alpha-synuclein fibrils
Biochemistry 50 (49): 10624-10636 (2011-12-13)

Gilbert D.F.; Erdmann G.; Zhang X.; Fritzsche A.; Demir K.; Jaedicke A.; Muehlenberg K.; Wanker E.E.; Boutros M.
A novel multiplex cell viability assay for high-throughput RNAi screening
PLoS ONE 6 (12): e28338 (2011-12-05)

Schierack P.; Weinreich J.; Ewers C.; Tachu B.; Nicholson B.; Barth S.
Hemolytic porcine intestinal Escherichia coli without virulence-associated genes typical of intestinal pathogenic E. coli
Applied and Environmental Microbiology 77 (23): 8451-8455 (2011-12)

Tamura T.; Sone M.; Iwatsubo T.; Tagawa K.; Wanker E.E.; Okazawa H.
Ku70 alleviates neurodegeneration in drosophila models of Huntington's disease
PLoS ONE 6 (11): e27408 (2011-11-07)

Vinayagam A.; Stelzl U.; Foulle R.; Plassmann S.; Zenkner M.; Timm J.; Assmus H.E.; Andrade-Navarro M.A.; Wanker E.E.
A directed protein interaction network for investigating intracellular signal transduction
Science Signaling 4 (189): rs8 (2011-09-06)

Imre L.; Balogh I.; Kappelmayer J.; Szabo M.; Melegh B.; Wanker E.; Szabo G.
Detection of mutations by flow cytometric melting point analysis of PCR products
Cytometry Part A 79A (9): 720-726 (2011-09)

Kieninger B.; Gioeva Z.; Krueger S.; Westermark G.T.; Friedrich R.P.; Faendrich M.; Roecken C.
PTAA and B10: new approaches to amyloid detection in tissue-evaluation of amyloid detection in tissue with a conjugated polyelectrolyte and a fibril-specific antibody fragment
Amyloid 18 (2): 47-52 (2011-06)

Schierack P.; Kleta S.; Tedin K.; Babila J.T.; Oswald S.; Oelschlaeger T.A.; Hiemann R.; Paetzold S.; Wieler L.H.
E. coli Nissle 1917 Affects Salmonella Adhesion to Porcine Intestinal Epithelial Cells
PLoS ONE 6 (2): e14712 (2011-02-17)

Dasari M.; Espargaro A.; Sabate R.; Lopez Del Amo J.M.; Fink U.; Grelle G.; Bieschke J.; Ventura S.; Reif B.
Bacterial inclusion bodies of Alzheimer's disease beta-amyloid peptides can be employed to study native-like aggregation intermediate states
Chembiochem 12 (3): 407-423 (2011-02-11)

Lilie H.; Baer D.; Kettner K.; Weininger U.; Balbach J.; Naumann M.; Mueller E.C.; Otto A.; Gast K.; Golbik R.; Kriegel T.
Yeast hexokinase isoenzyme ScHxk2: stability of a two-domain protein with discontinuous domains
Protein Engineering Design and Selection 24 (1-2): 79-87 (2011-01)


Kuettner E.B.; Kettner K.; Keim A.; Svergun D.I.; Volke D.; Singer D.; Hoffmann R.; Mueller E.C.; Otto A.; Kriegel T.M.; Straeter N.
Crystal structure of hexokinase KlHxk1 of Kluyveromyces lactis: a molecular basis for understanding the control of yeast hexokinase functions via covalent modification and oligomerization
Journal of Biological Chemistry 285 (52): 41019-41033 (2010-12-24)

Bieschke J.
Gruener Tee - neue Einsichten fuer einen alten Wirkstoff [Green tea - new insights for an old drug]
Chemie in unserer Zeit 44 (4): 306-307 (2010-08)

Marras E.; Travaglione A.; Chaurasia G.; Futschik M.; Capobianco E.
Inferring modules from human protein interactome classes
BMC Systems Biology 4: 105 (2010-07-23)

Enokido Y.; Tamura T.; Ito H.; Arumughan A.; Komuro A.; Shiwaku H.; Sone M.; Foulle R.; Sawada H.; Ishiguro H.; Ono T.; Murata M.; Kanazawa I.; Tomilin N.; Tagawa K.; Wanker E.E.; Okazawa H.
Mutant huntingtin impairs Ku70-mediated DNA repair
Journal of Cell Biology 189 (3): 425-443 (2010-05-03)

Bieschke J.; Russ J.; Friedrich R.P.; Ehrnhoefer D.E.; Wobst H.; Neugebauer K.; Wanker E.E.
EGCG remodels mature {alpha}-synuclein and amyloid-{beta} fibrils and reduces cellular toxicity
Proceedings of the National Academy of Sciences of the United States of America 107 (17): 7710-7715 (2010-04-27)

Porras P.; McDonagh B.; Pedrajas J.R.; Barcena J.A.; Padilla C.A.
Structure and function of yeast glutaredoxin 2 depend on postranslational processing and are related to subcellular distribution
Biochimica et Biophysica Acta - Proteins and Proteomics 1804 (4): 839-845 (2010-04)

Goehler H.; Droege A.; Lurz R.; Schnoegl S.; Chernoff Y.O.; Wanker E.E.
Pathogenic polyglutamine tracts are potent inducers of spontaneous sup35 and rnq1 amyloidogenesis
PLoS ONE 5 (3): e9642 (2010-03-10)

Vinayagam A.; Stelzl U.; Wanker E.E.
Repeated two-hybrid screening detects transient protein-protein interactions
Theoretical Chemistry Accounts 125 (3-6): 613-619 (2010-03)

Patzke C.; Max K.E.; Behlke J.; Schreiber J.; Schmidt H.; Dorner A.A.; Kroeger S.; Henning M.; Otto A.; Heinemann U.; Rathjen F.G.
The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells
Journal of Neuroscience 30 (8): 2897-2910 (2010-02-24)


Kegel K.B.; Schewkunow V.; Sapp E.; Masso N.; Wanker E.E.; Difiglia M.; Goldmann W.H.
Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers
Biochemical and Biophysical Research Communications 387 (3): 472-475 (2009-09-25)

Figueroa A.; Kotani H.; Toda Y.; Mazan-Mamczarz K.; Mueller E.C.; Otto A.; Disch L.; Norman M.; Ramdasi R.; Keshtgar M.; Gorospe M.; Fujita Y.
Novel roles of Hakai in cell proliferation and oncogenesis
Molecular Biology of the Cell 20 (15): 3533-3542 (2009-08)

Salta E.; Panagiotidis C.; Teliousis K.; Petrakis S.; Eleftheriadis E.; Arapoglou F.; Grigoriadis N.; Nicolaou A.; Kaldrymidou E.; Krey G.; Sklaviadis T.
Evaluation of the possible transmission of BSE and scrapie to gilthead sea bream (Sparus aurata)
PLoS ONE 4 (7): e6175 (2009-07-28)

Palidwor G.A.; Shcherbinin S.; Huska M.R.; Rasko T.; Stelzl U.; Arumughan A.; Foulle R.; Porras P.; Sanchez-Pulido L.; Wanker E.E.; Andrade-Navarro M.A.
Detection of alpha-rod protein repeats using a neural network and application to huntingtin
PLoS Computational Biology 5 (3): e1000304 (2009-03-13)

Chirasani S.R.; Markovic D.S.; Synowitz M.; Eichler S.A.; Wisniewski P.; Kaminska B.; Otto A.; Wanker E.; Schaefer M.; Chiarugi P.; Meier J.C.; Kettenmann H.; Glass R.
Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells
Journal of Molecular Medicine 87 (2): 153-167 (2009-02)

Tamura T.; Sone M.; Yamashita M.; Wanker E.E.; Okazawa H.
Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in drosophila models
PLoS ONE 4 (1): e4262 (2009-01-23)

Chaurasia G.; Malhotra S.; Russ J.; Schnoegl S.; Haenig C.; Wanker E.E.; Futschik M.E.
UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome
Nucleic Acids Research 37 (Database Issue): D657-D660 (2009-01)

Venkatesan K.; Rual J.F.; Vazquez A.; Stelzl U.; Lemmens I.; Hirozane-Kishikawa T.; Hao T.; Zenkner M.; Xin X.; Goh K.I.; Yildirim M.A.; Simonis N.; Heinzmann K.; Gebreab F.; Sahalie J.M.; Cevik S.; Simon C.; de Smet A.S.; Dann E.; Smolyar A.; Vinayagam A.; Yu H.; Szeto D.; Borick H.; Dricot A.; Klitgord N.; Murray R.R.; Lin C.; Lalowski M.; Timm J.; Rau K.; Boone C.; Braun P.; Cusick M.E.; Roth F.P.; Hill D.E.; Tavernier J.; Wanker E.E.; Barabasi A.L.; Vidal M.
An empirical framework for binary interactome mapping
Nature Methods 6 (1): 83-90 (2009-01)


Zolghadr K.; Mortusewicz O.; Rothbauer U.; Kleinhans R.; Goehler H.; Wanker E.E.; Cardoso M.C.; Leonhardt H.
A fluorescent two-hybrid (F2H) assay for direct visualization of protein interactions in living cells
Molecular and Cellular Proteomics 7 (11): 2279-2287 (2008-11-01)

Minnerop M.; Herbst M.; Fimmers R.; Matz B.; Klockgether T.; Wuellner U.
Bell's palsy: combined treatment of famciclovir and prednisone is superior to prednisone alone
Journal of Neurology 255 (11): 1726-1730 (2008-11)

Klinke T.; Rump A.; Poenisch R.; Schellenberger W.; Mueller E.C.; Otto A.; Klimm W.; Kriegel T.M.
Identification and characterization of CaApe2 – a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans
FEMS Yeast Research 8 (6): 858-869 (2008-09)

Winter J.; Roepcke S.; Krause S.; Mueller E.C.; Otto A.; Vingron M.; Schweiger S.
Comparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines
PLoS ONE 3 (7): e2780 (2008-07-23)

Inagaki R.; Tagawa K.; Qi M.L.; Enokido Y.; Ito H.; Tamura T.; Shimizu S.; Oyanagi K.; Arai N.; Kanazawa I.; Wanker E.E.; Okazawa H.
Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington's disease
European Journal of Neuroscience 28 (1): 30-40 (2008-07)

Ehrnhoefer D.E.; Bieschke J.; Boeddrich A.; Herbst M.; Masino L.; Lurz R.; Engemann S.; Pastore A.; Wanker E.E.
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
Nature Structural & Molecular Biology 15 (6): 558-566 (2008-06)

Mereles D.; Wanker E.E.; Katus H.A.
Therapy effects of green tea in a patient with systemic light-chain amyloidosis
Clinical Research in Cardiology 97 (5): 341-344 (2008-05)

Aranda-Orgilles B.; Trockenbacher A.; Winter J.; Aigner J.; Koehler A.; Jastrzebska E.; Stahl J.; Mueller E.C.; Otto A.; Wanker E.E.; Schneider R.; Schweiger S.
The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex
Human Genetics 123 (2): 163-176 (2008-03)

Stoeckl M.; Fischer P.; Wanker E.E.; Herrmann A.
Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains
Journal of Molecular Biology 375 (5): 1394-1404 (2008-02-01)

Matuschewski K.; Schueler H.
Actin/myosin-based gliding motility in apicomplexan parasites
Subcellular Biochemistry 47 (47): 110-120 (2008)

Schueler H.; Peti W.
Structure-function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin
FEBS Journal 275 (1): 59-68 (2008-01)


Kettner K.; Mueller E.C.; Otto A.; Roedel G.; Breunig K.D.; Kriegel T.M.
Identification and characterization of a novel glucose-phosphorylating enzyme in Kluyveromyces lactis
FEMS Yeast Research 7 (5): 683-692 (2007-08)

Herbst M.; Wanker E.E.
Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy
Neurodegenerative Diseases 4 (2-3): 254-260 (2007-06)

Qi M.L.; Tagawa K.; Enokido Y.; Yoshimura N.; Wada Y.I.; Watase K.; Ishiura S.I.; Kanazawa I.; Botas J.; Saitoe M.; Wanker E.E.; Okazawa H.
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases
Nature Cell Biology 9 (4): 402-414 (2007-04)

Futschik M.E.; Chaurasia G.; Herzel H.
Comparison of human protein-protein interaction maps
Bioinformatics 23 (5): 605-611 (2007-03)

Chaurasia G.; Iqbal Y.; Haenig C.; Herzel H.; Wanker E.E.; Futschik M.E.
Flexible web-based integration of distributed large-scale human protein interaction maps
Journal of Integrative Bioinformatics 4 (1): 51 (2007-02-26)

Stenmark P.; Kursula P.; Flodin S.; Graeslund S.; Landry R.; Nordlund P.; Schueler H.
Crystal structure of human inosine triphosphatase: Substrate binding and implication of the itpa deficiency mutation p32T
Journal of Biological Chemistry 282 (5): 3182-3187 (2007-02-02)

Huebbers C.U.; Clemen C.S.; Kesper K.; Boeddrich A.; Hofmann A.; Kaemaeraeinen O.; Tolksdorf K.; Stumpf M.; Reichelt J.; Roth U.; Krause S.; Watts G.; Kimonis V.; Wattjes M.P.; Reimann J.; Thal D.R.; Biermann K.; Evert B.O.; Lochmueller H.; Wanker E.E.; Schoser B.G.; Noegel A.A.; Schroeder R.
Pathological consequences of VCP mutations on human striated muscle
Brain 130 (2): 381-393 (2007-02-01)

Tagawa K.; Marubuchi S.; Qi M.L.; Enokido Y.; Tamura T.; Inagaki R.; Murata M.; Kanazawa I.; Wanker E.E.; Okazawa H.
The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes
Journal of Neuroscience 27 (4): 868-880 (2007-01-24)

Behlke J.; Ristau O.; Mueller E.C.; Hannemann F.; Bernhardt R.
Self-association of adrenodoxin studied by using analytical ultracentrifugation
Biophysical Chemistry 125 (1): 159-165 (2007-01)

Chaurasia G.; Iqbal Y.; Haenig C.; Herzel H.; Wanker E.E.; Futschik M.E.
UniHI: an entry gate to the human protein interactome
Nucleic Acids Research 35 (Database Issue): D590-D594 (2007-01)


Weidemann W.; Stelzl U.; Lisewski U.; Bork K.; Wanker E.E.; Hinderlich S.; Horstkorte R.
The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis
FEBS Letters 580 (28): 6649-6654 (2006-12-11)

Stelzl U.; Wanker E.E.
The value of high quality protein-protein interaction networks for systems biology
Current Opinion in Chemical Biology 10 (6): 551-558 (2006-12)

Schueler H.; Matuschewski K.
Regulation of apicomplexan microfilament dynamics by a minimal set of actin-binding proteins
Traffic 7 (11): 1433-1439 (2006-11)

Zemojtel T.; Froehlich A.; Palmieri M.C.; Kolanczyk M.; Mikula I.; Wyrwicz L.S.; Wanker E.E.; Mundlos S.; Vingron M.; Martasek P.; Durner J.
Plant nitric oxide synthase: a never-ending story?
Trends Plant Sci 11 (11): 524-525 (2006-11)

Wolski W.E.; Farrow M.; Emde A.K.; Lehrach H.; Lalowski M.; Reinert K.
Analytical model of peptide mass cluster centres with applications
Proteome Science 4: 18 (2006-09-23)

Ehrnhoefer D.E.; Duennwald M.; Markovic P.; Wacker J.L.; Engemann S.; Roark M.; Legleiter J.; Marsh J.L.; Thompson L.M.; Lindquist S.; Muchowski P.J.; Wanker E.E.
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
Human Molecular Genetics 15 (18): 2743-2751 (2006-09-15)

Jeub M.; Herbst M.; Spauschus A.; Fleischer H.; Klockgether T.; Wuellner U.; Evert B.O.
Potassium channel dysfunction and depolarized resting membrane potential in a cell model of SCA3
Exp Neurol 201 (1): 182-192 (2006-09-01)

Horn S.C.; Lalowski M.; Goehler H.; Droege A.; Wanker E.E.; Stelzl U.
Huntingtin interacts with the receptor sorting family protein GASP2
Journal of Neural Transmission 113 (8): 1081-1090 (2006-08)

Kursula P.; Flodin S.; Ehn M.; Hammarstroem M.; Schueler H.; Nordlund P.; Stenmark P.
Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy
Acta Crystallographica Section F 62 (7): 613-617 (2006-07-01)

Hufton A.L.; Vinayagam A.; Suhai S.; Baker J.C.
Genomic analysis of Xenopus organizer function
BMC Developmental Biology 6: 27 (2006-06-06)

Kessels M.M.; Dong J.; Leibig W.; Westermann P.; Qualmann B.
Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network
Journal of Cell Science 119 (8): 1504-1516 (2006-04-15)

Boeddrich A.; Gaumer S.; Haacke A.; Tzvetkov N.; Albrecht M.; Evert B.O.; Mueller E.C.; Lurz R.; Breuer P.; Schugardt N.; Plassmann S.; Xu K.; Warrick J.M.; Suopanki J.; Wuellner U.; Frank R.; Hartl U.F.; Bonini N.M.; Wanker E.E.
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
EMBO Journal 25 (7): 1547-1558 (2006-04-05)

Schueler H.; Matuschewski K.
Plasmodium motility: actin not actin' like actin
Trends in Parasitology 22 (4): 146-147 (2006-04)

Hoshino M.; Qi M.L.; Yoshimura N.; Miyashita T.; Tagawa K.; Wada Y.I.; Enokido Y.; Marubuchi S.; Arai P.; Arai N.; Oyanagi K.; Blandino G.; Sudol M.; Rich T.; Kanazawa I.; Wanker E.E.; Saitoe M.; Okazawa H.
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73
Journal of Cell Biology 172 (4): 589-604 (2006-02-13)

Gizatullina Z.Z.; Lindenberg K.S.; Harjes P.; Chen Y.; Kosinski C.M.; Landwehrmeyer B.G.; Ludolph A.C.; Striggow F.; Zierz S.; Gellerich F.N.
Low stability of huntington muscle mitochondria against Ca2+ in R6/2 mice
Annals of Neurology 59 (2): 407-411 (2006-02)

Grelle G.; Kostka S.; Otto A.; Kersten B.; Genser K.F.; Mueller E.C.; Waelter S.; Boeddrich A.; Stelzl U.; Haenig C.; Volkmer-Engert R.; Landgraf C.; Alberti S.; Hoehfeld J.; Stroedicke M.; Wanker E.E.
Identification of VCP/p97, CHIP and amphiphysin II interaction partners using membrane-based human proteome arrays
Molecular & Cellular Proteomics 5 (2): 234-244 (2006-02-01)

Suopanki J.; Goetz C.; Lutsch G.; Schiller J.; Harjes P.; Herrmann A.; Wanker E.E.
Interaction of huntingtin fragments with brain membranes - clues to early dysfunction in Huntington's disease
Journal of Neurochemistry 96 (3): 870-884 (2006-02)

Schueler H.; Karlsson R.; Schutt C.E.; Lindberg U.
The connection between actin ATPase and polymerization
Advances in Molecular and Cell Biology 37: 49-66 (2006)

Herbst M.; Wanker E.E.
Therapeutic approaches to polyglutamine diseases: combating protein misfolding and aggregation
Current Pharmaceutical Design 12 (20): 2543-2555 (2006)

Chaurasia G.; Herzel H.; Wanker E.E.; Futschik M.E.
Systematic functional assessment of human protein-protein interaction maps
Genome Inform 17: 36-45 (2006)

Stelzl U.; Wanker E.E.
Protein-Wechselwirkungsnetzwerke: Aufklaerung der Funktion von Proteinen
Biologie in unserer Zeit 36 (1): 12-13 (2006-01)

Mueller E.C.
Mass spectrometry: ESI
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1020-1022 (2006)

Droege A.
Recombinant protein production in mammalian cell culture
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1616-1620 (2006)

Hockly E.; Tse J.; Barker A.L.; Moolman D.L.; Beunard J.L.; Revington A.P.; Holt K.; Sunshine S.; Moffitt H.; Sathasivam K.; Woodman B.; Wanker E.E.; Lowden P.A.; Bates G.P.
Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease
Neurobiology of Disease 21 (1): 228-236 (2006-01)


Wolski W.E.; Lalowski M.; Martus P.; Herwig R.; Giavalisco P.; Gobom J.; Sickmann A.; Lehrach H.; Reinert K.
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process
BMC Bioinformatics 6: 285 (2005-11-30)

Mirgorodskaya E.; Wanker E.E.; Otto A.; Lehrach H.; Gobom J.
Method for qualitative comparisons of protein mixtures based on enzyme-catalyzed stable-isotope incorporation
Journal of Proteome Research 4 (6): 2109-2116 (2005-11-01)

Simoes I.; Mueller E.C.; Otto A.; Bur D.; Cheung A.Y.; Faro C.; Pires E.
Molecular analysis of the interaction between cardosin A and phospholipase Dalpha
FEBS Journal 272 (22): 5786-5798 (2005-11-01)

Stelzl U.; Worm U.; Lalowski M.; Haenig C.; Brembeck F.H.; Goehler H.; Stroedicke M.; Zenkner M.; Schoenherr A.; Koeppen S.; Timm J.; Mintzlaff S.; Abraham C.; Bock N.; Kietzmann S.; Goedde A.; Toksoez E.; Droege A.; Krobitsch S.; Korn B.; Birchmeier W.; Lehrach H.; Wanker E.E.
A human protein-protein interaction network: a resource for annotating the proteome
Cell 122 (6): 957-968 (2005-09-23)

Ralser M.; Nonhoff U.; Albrecht M.; Lengauer T.; Wanker E.E.; Lehrach H.; Krobitsch S.
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
Human Molecular Genetics 14 (19): 2893-2909 (2005-08-22)

Wolski W.E.; Lalowski M.; Jungblut P.; Reinert K.
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
BMC Bioinformatics 6: 203 (2005-08-15)

Kersten B.; Wanker E.E.; Hoheisel J.D.; Angenendt P.
Multiplex approaches in protein microarray technology
Expert Review of Proteomics 2 (4): 499-510 (2005-08-01)

Ralser M.; Goehler H.; Wanker E.E.; Lehrach H.; Krobitsch S.
Generation of a yeast two-hybrid strain suitable for competitive protein binding analysis
Biotechniques 39 (2): 165-168 (2005-08-01)

Daechsel J.C.; Luecking C.B.; Deeg S.; Schultz E.; Lalowski M.; Casademunt E.; Corti O.; Hampe C.; Patenge N.; Vaupel K.; Yamamoto A.; Dichgans M.; Brice A.; Wanker E.E.; Kahle P.J.; Gasser T.
Parkin interacts with the proteasome subunit alpha4
FEBS Letters 579 (18): 3913-3919 (2005-07-18)

Feilner T.; Hultschig C.; Lee J.; Meyer S.; Immink R.G.; Koenig A.; Possling A.; Seitz H.; Beveridge A.; Scheel D.; Cahill D.J.; Lehrach H.; Kreutzberger J.; Kersten B.
High-throughput identification of potential Arabidopsis MAP kinases substrates
Molecular & Cellular Proteomics 4 (10): 1558-1568 (2005-07-11)

Karapetian R.N.; Evstafieva A.G.; Abaeva I.S.; Chichkova N.V.; Filonov G.S.; Rubtsov Y.P.; Sukhacheva E.A.; Melnikov S.V.; Schneider U.; Wanker E.E.; Vartapetian A.B.
Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes
Molecular and Cellular Biology 25 (3): 1089-1099 (2005-02-01)

Zhang X.; Smith D.L.; Meriin A.B.; Engemann S.; Russel D.E.; Roark M.; Washington S.L.; Maxwell M.M.; Marsh J.L.; Thompson L.M.; Wanker E.E.; Young A.B.; Housman D.E.; Bates G.P.; Sherman M.Y.; Kazantsev A.G.
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo
Proceedings of the National Academy of Sciences of the United States of America 102 (3): 892-897 (2005-01-18)

Herbst M.; Wattjes M.P.; Urbach H.; Inhetvin-Hutter C.; Becker D.; Kjockgether T.; Hartmann A.
Cerebral embolism from left atrial myxoma leading to cerebral and retinal aneurysms: A case report
American Journal of Neuroradiology 26 (3): 666-669 (2005-01-01)

Yu M.; Schreek S.; Cerni C.; Schamberger C.; Lesniewicz K.; Poreba E.; Vervoorts J.; Walsemann G.; Groetzinger J.; Kremmer E.; Mehraein Y.; Mertsching J.; Kraft R.; Austen M.; Luscher-Firzlaff J.; Luescher B.
PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation
Oncogene 24 (12): 1982-1993 (2005-01-01)

Bardischewsky F.; Quentmeier A.; Rother D.; Hellwig P.; Kostka S.; Friedrich C.G.
Sulfur dehydrogenase of Paracoccus pantotrophus: The heme-2 domain of the molybdoprotein cytochrome c complex is dispensable for catalytic activity
Biochemistry 44 (18): 7024-7034 (2005-01-01)

Mologni L.; Moza M.; Lalowski M.M.; Carpen O.
Characterization of mouse myotilin and its promoter
Biochemical and Biophysical Research Communications 329 (3): 1001-1009 (2005-01-01)


Goehler H.; Lalowski M.; Stelzl U.; Waelter S.; Stroedicke M.; Worm U.; Droege A.; Lindenberg K.S.; Knoblich M.; Haenig C.; Herbst M.; Suopanki J.; Scherzinger E.; Abraham C.; Bauer B.; Hasenbank R.; Fritzsche A.; Ludewig A.H.; Buessow K.; Coleman S.H.; Gutekunst C.A.; Landwehrmeyer B.G.; Lehrach H.; Wanker E.E.
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease
Molecular Cell 15 (6): 853-865 (2004-09-24)

Blume A.; Weidemann W.; Stelzl U.; Wanker E.E.; Lucka L.; Donner P.; Reutter W.; Horstkorte R.; Hinderlich S.
Domain specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
Biochemical Journal 384 (3): 599-607 (2004-08-26)

Qin Z.H.; Wang Y.; Sapp E.; Cuiffo B.; Wanker E.; Hayden M.R.; Kegel K.B.; Aronin N.; DiFiglia M.
Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction
Journal of Neuroscience 7 (1): 269-281 (2004-01-07)

Wanker E.E.; Schnoegl S.
Grossfahndung nach Hemmstoffen
Spektrum der Wissenschaft (1): 64-65 (2004-01)

Wehrl W.; Meyer T.F.; Jungblut P.R.; Mueller E.C.; Szczepek A.J.
Action and reaction: Chlamydophila pneumoniae proteome alteration in a persistent infection induced by iron deficiency
Proteomics 4 (10): 2969-2981 (2004-01-01)

Albrecht A.N.; Kornak U.; Boeddrich A.; Suering K.; Robinson P.N.; Stiege A.C.; Lurz R.; Stricker S.; Wanker E.E.; Mundlos S.
A molecular pathogenesis for transcription factor associated poly-alanine tract expansions
Human Molecular Genetics 13 (20): 2351-2359 (2004-01-01)

Okkels L.M.; Mueller E.C.; Schmid M.; Rosenkrands I.; Kaufmann S.H.E.; Andersen P.; Jungblut P.R.
CFP10 discriminates between nonacetylated and acetylated ESAT-6 of Mycobacterium tuberculosis by differential interaction
Proteomics 4 (10): 2954-2960 (2004-01-01)

Kilian K.; Dernedde J.; Mueller E.C.; Bahr I.; Tauber R.
The interaction of protein kinase C isozymes {alpha}, {iota}, and {theta} with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor
Journal of Biological Chemistry 279 (33): 34472-34480 (2004-01-01)

Schiffler B.; Bureik M.; Reinle W.; Mueller E.C.; Hannemann F.; Bernhardt R.
The adrenodoxin-like ferredoxin of Schizosaccharomyces pombe mitochondria
Journal of Inorganic Biochemistry 98 (7): 1229-1237 (2004-01-01)

Sajidan A.; Farouk A.; Greiner R.; Jungblut P.; Mueller E.C.; Borriss R.
Molecular and physiological characterisation of a 3-phytase from soil bacterium Klebsiella sp. ASR1
Applied Microbiology and Biotechnology 65 (1): 110-118 (2004-01-01)

Tagawa K.; Hoshino M.; Okuda T.; Ueda H.; Hayashi H.; Engemann S.; Okado H.; Ichikawa M.; Wanker E.E.; Okazawa H.
Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein
Journal of Neurochemistry 89 (4): 974-987 (2004-01-01)

Gruenberg K.; Mueller E.C.; Otto A.; Reszka R.; Linder D.; Kube M.; Reinhardt R.; Schueler D.
Biochemical and proteomic analysis of the magnetosome membrane in Magnetospitillum gryphiswaldense
Applied and Environmental Microbiology 70 (2): 1040-1050 (2004-01-01)

Schnoegl S.; Wanker E.E.
Grossfahndung nach Hemmstoffen : Huntington-Forschung in Deutschland
Spektrum der Wissenschaft 1: 64-65 (2004-01-01)


Busch A.; Engemann S.; Lurz R.; Okazawa H.; Lehrach H.; Wanker E.E.
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin - A potential mechanism for loss of huntingtin function in Huntington's disease
Journal of Biological Chemistry 278 (42): 41452-41461 (2003-10-17)

Baer D.; Golbik R.; Huebner G.; Lilie H.; Mueller E.C.; Naumann M.; Otto A.; Reuter R.; Breunig K.D.; Kriegel T.M.
The unique hexokinase of Kluyveromyces lactis - Molecular and functional characterization and evaluation of a role in glucose signaling
Journal of Biological Chemistry 278 (41): 39280-39286 (2003-10-10)

Harjes P.; Wanker E.E.
The hunt for huntingtin function: interaction partners tell many different stories
Trends in Biochemical Sciences 28 (8): 425-433 (2003-08)

Magro G.; Perissinotto D.; Schiappacassi M.; Goletz S.; Otto A.; Mueller E.C.; Bisceglia M.; Brown G.; Ellis T.; Grasso S.; Colombatti A.; Perris R.
Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas
American Journal of Pathology 163 (1): 183-196 (2003-07)

Andersen O.M.; Yeung C.H.; Vorum H.; Wellner M.; Andreassen T.K.; Erdmann B.; Mueller E.C.; Herz J.; Otto A.; Cooper T.G.; Willnow T.E.
Essential role of the apolipoprotein E receptor-2 in sperm development
Journal of Biological Chemistry 278 (26): 23989-23995 (2003-06-27)

Klein H.; Mueller S.; Loeschner B.; Toenjes R.R.; Braun G.; Mueller E.C.; Otto A.; Montag T.
Cloning, sequencing and recombinant expression of the open reading frame encoding a novel member of the Sarcocystis muris (Apicomplexa) microneme lectin family
Parasitology Research 90 (1): 84-86 (2003-05)

Odintsova T.I.; Mueller E.C.; Ivanov A.V.; Egorov T.A.; Bienert R.; Vladimirov S.N.; Kostka S.; Otto A.; Wittmann-Liebold B.; Karpova G.G.
Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing
Journal of Protein Chemistry 22 (3): 249-258 (2003-04)

Czupalla C.; Culo M.; Mueller E.C.; Brock C.; Reusch H.P.; Spicher K.; Krause E.; Nuernberg B.
Identification and characterization of the autophosphorylation sites of phosphoinositide 3-kinase isoforms beta and gamma
Journal of Biological Chemistry 278 (13): 11536-11545 (2003-03-28)

Bollig F.; Winzen R.; Gaestel M.; Kostka S.; Resch K.; Holtmann H.
Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization
Biochemical and Biophysical Research Communications 301 (3): 665-670 (2003-02-14)

Ross C.A.; Poirier M.A.; Wanker E.E.; Amzel M.
Polyglutamine fibrillogenesis: The pathway unfolds
Proceedings of the National Academy of Sciences of the United States of America 100 (1): 1-3 (2003-01-07)

Stelzl U.; Zengel J.M.; Tovbina M.; Walker M.; Nierhaus K.H.; Lindahl L.; Patel D.J.
RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon
Journal of Biological Chemistry 278 (30): 28237-28245 (2003-01-01)

Mattow J.; Schaible U.E.; Schmidt F.; Hagens K.; Siejak R.; Brestrich G.; Haeselbarth G.; Mueller E.C.; Jungblut P.R.; Kaufmanni S.H.E.
Comparative proteome analysis of culture supernatant proteins from virulent Mycobacterium tuberculosis H37Rv and attenuated M-bovis BCG Copenhagen
Electrophoresis 24 (19-20): 3405-3420 (2003-01-01)

Laurine E.; Gregoire C.; Faendrich M.; Engemann S.; Marchal S.; Thion L.; Mohr M.; Monsarrat B.; Michel B.; Dobson C.M.; Wanker E.E.; Erard M.; Verdier J.M.
Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease
Journal of Biological Chemistry 278 (51): 51770-51778 (2003-01-01)

Hoshino M.; Tagawa K.; Okuda T.; Murata M.; Oyanagi K.; Arai N.; Mizutani T.; Kanazawa I.; Wanker E.E.; Okazawa H.
Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein
Journal of Neurochemistry 87 (1): 257-267 (2003-01-01)

Gonzalez L.J.; Castellanos-Serra L.; Badock V.; Diaz M.; Moro A.; Perea S.; Santos A.; Paz-Lago D.; Otto A.; Mueller E.C.; Kostka S.; Wittmann-Liebold B.; Padron G.
Identification of nuclear proteins of small cell lung cancer cell line H82: An improved procedure for the analysis of silver-stained proteins
Electrophoresis 24 (1-2): 237-252 (2003-01)

Boeddrich A.; Lurz R.; Wanker E.E.
Huntingtin fragments form aggresome-like inclusion bodies in mammalian cells
Methods in Molecular Biology 232: 217-229 (2003)


Heiser V.; Engemann S.; Broecker W.; Dunkel I.; Boeddrich A.; Waelter S.; Nordhoff E.; Lurz R.; Schugardt N.; Rautenberg S.; Herhaus C.; Barnickel G.; Boettcher H.; Lehrach H.; Wanker E.E.
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay
Proceedings of the National Academy of Sciences of the United States of America 99 (Suppl 4): 16400-16406 (2002-12-10)

Calado A.; Treichel N.; Mueller E.C.; Otto A.; Kutay U.
Exportin-5-mediated nuclear export of eukaryotic elongation factor 1A and tRNA
EMBO Journal 21 (22): 6216-6224 (2002-11-15)

Muecke M.; Grelle G.; Behlke J.; Kraft R.; Krueger D.H.; Reuter M.
EcoRII: a restriction enzyme evolving recombination functions
EMBO Journal 21 (19): 5262-5268 (2002-10-01)

Peterbauer C.K.; Litscher D.; Kubicek C.P.
The Trichoderma atroviride seb1 (stress response element binding) gene encodes an AGGGG-binding protein which is involved in the response to high osmolarity stress
Molecular Genetics and Genomics 268 (2): 223-231 (2002-10)

Contzen J.; Kostka S.; Kraft R.; Jung C.
Intermolecular electron transfer in cytochrome P450cam covalently bound with Tris(2,2'-bipyridyl)ruthenium(II): structural changes detected by FTIR spectroscopy
Journal of Inorganic Biochemistry 91 (4): 607-617 (2002-09-20)

Lebeau A.; Zeindl-Eberhart E.; Mueller E.C.; Mueller-Hoecker J.; Jungblut P.R.; Emmerich B.; Loehrs U.
Generalized crystal-storing histiocytosis associated with monoclonal gammopathy: molecular analysis of a disorder with rapid clinical course and review of the literature
Blood 100 (5): 1817-1827 (2002-09-01)

Moencke-Buchner E.; Reich S.; Muecke M.; Reuter M.; Messer W.; Wanker E.E.; Krueger D.H.
Counting CAG repeats in the Huntington's disease gene by restriction endonuclease EcoP15I cleavage
Nucleic Acids Research 30 (16): e83 (2002-08-15)

Li P.F.; Li J.C.; Mueller E.C.; Otto A.; Dietz R.; von Harsdorf R.
Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC
Molecular Cell 10 (2): 247-258 (2002-08)

Srisomsap C.; Subhasitanont P.; Otto A.; Mueller E.C.; Punyarit P.; Wittmann-Liebold B.; Svasti J.
Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis
Proteomics 2 (6): 706-712 (2002-06-17)

Muecke M.; Pingoud V.; Grelle G.; Kraft R.; Krueger D.H.; Reuter M.
Asymmetric photocross-linking pattern of restriction endonuclease EcoRII to the DNA recognition sequence
Journal of Biological Chemistry 277 (16): 14288-14293 (2002-04-19)

Perutz M.F.; Pope B.J.; Owen D.; Wanker E.E.; Scherzinger E.
Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid {beta}-peptide of amyloid plaques
Proceedings of the National Academy of Sciences of the United States of America 99 (8): 5596-5600 (2002-04-16)

Albrecht A.N.; Schwabe G.C.; Stricker S.; Boeddrich A.; Wanker E.E.; Mundlos S.
The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements
Mechanisms of Development 112: 53-67 (2002-03-01)

Wanker E.E.
Hip1 and Hippi participate in a novel cell death-signaling pathway
Developmental Cell 2 (2): 126-128 (2002-02)


Smith D.L.; Portier R.; Woodman B.; Hockly E.; Mahal A.; Klunk W.E.; Li X.J.; Wanker E.E.; Murray K.D.; Bates G.P.
Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles
Neurobiology of Diseases 8: 1017-1026 (2001-12-01)

Mauch D.H.; Naegler K.; Schumacher S.; Goeritz C.; Mueller E.C.; Otto A.; Pfrieger F.W.
CNS synaptogenesis promoted by glia-derived cholesterol
Science 294 (5545): 1354-1357 (2001-11-09)

Andreeva A.Y.; Krause E.; Mueller E.C.; Blasig I.E.; Utepbergenov D.I.
Protein kinase C regulates the phosphorylation and cellular localization of occludin
Journal of Biological Chemistry 276 (42): 38480-38486 (2001-10-19)

Sathasivam K.; Woodman B.; Mahal A.; Bertaux F.; Wanker E.E.; Shima D.T.; Bates G.P.
Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients
Human Molecular Genetics 10: 2425-2435 (2001-10-01)

Waelter S.; Scherzinger E.; Hasenbank R.; Nordhoff E.; Lurz R.; Goehler H.; Gauss C.; Sathasivam K.; Bates G.P.; Lehrach H.; Wanker E.E.
The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis
Human Molecular Genetics 10: 1807-1817 (2001-08-15)

Sittler A.; Lurz R.; Lueder G.; Priller J.; Lehrach H.; Hayer-Hartl M.K.; Hartl F.U.; Wanker E.E.
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
Human Molecular Genetics 10: 1307-1315 (2001-06-01)

Waelter S.; Boeddrich A.; Lurz R.; Scherzinger E.; Lueder G.; Lehrach H.; Wanker E.E.
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation
Molecular Biology of the Cell 12 (5): 1393-1407 (2001-05)

Backert S.; Mueller E.C.; Jungblut P.R.; Meyer T.F.
Tyrosine phosphorylation patterns and size modification of the Helicobacter pyori CagA protein after translocation into gastric epithelial cells
Proteomics 1 (4): 608-617 (2001-04)

Badock V.; Steinhusen U.; Bommert K.; Wittmann-Liebold B.; Otto A.
Apoptosis-induced cleavage of keratin 15 and keratin 17 in a human breast epithelial cell line
Cell Death and Differentiation 8 (3): 308-315 (2001-03-01)

Hermann R.; Hensel F.; Mueller E.C.; Keppler M.; Souto-Carneiro M.; Braendlein S.; Mueller-Hermelink H.K.; Vollmers H.P.
Deactivation of regulatory proteins hnRNP A1 and A2 during SC-1 induced apoptosis
Human Antibodies 10 (2): 83-90 (2001)

Griffoni C.; Laktionov P.P.; Rykova E.Y.; Spisni E.; Riccio M.; Santi S.; Bryksin A.; Volodko N.; Kraft R.; Vlassov V.; Tomasi V.
The Rossmann fold of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a nuclear docking site for antisense oligonucleotides containing a TAAAT motif
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1530 (1): 32-46 (2001-01-01)

Bech-Otschir D.; Kraft R.; Huang X.H.; Henklein P.; Kapelari B.; Pollmann C.; Dubiel W.
COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
EMBO Journal 20 (7): 1630-1639 (2001-01-01)

Tomasi V.; Laktionov P.P.; Bryksin A.V.; Volod'ko N.V.; Griffoni C.; Rykova E.V.; Spisni E.; Kraft R.; Vlassov V.V.
Glyceraldehyde-3-phosphate dehydrogenase is responsible for intranuclear localization of some oligonucleotides
Nucleosides Nucleotides & Nucleic Acids 20: 863-867 (2001-01-01)

Wieske M.; Benndorf R.; Behlke J.; Doelling R.; Grelle G.; Bielka H.; Lutsch G.
Defined sequence segments of the small heat shock proteins HSP25 and alphaB-crystallin inhibit actin polymerization
European Journal of Biochemistry 268 (7): 2083-2090 (2001-01-01)

Koritschoner N.P.; Madruga J.; Knespel S.; Blendinger G.; Anzinger B.; Otto A.; Zenke M.; Bartunek P.
The nuclear orphan receptor TR4 promotes proliferation of myeloid progenitor cells
Cell Growth and Differentiation 12 (11): 563-572 (2001-01-01)

Harms G.; Kraft R.; Grelle G.; Volz B.; Dernedde J.; Tauber R.
Identification of nucleolin as a new L-selectin ligand
Biochemical Journal 360: 531-538 (2001-01-01)

Zimdahl H.; Goesele C.; Luetjens G.; Gruetzner F.; Kreitler T.; Voss K.; Wanker E.E.; Knoblauch M.
Assignment of the huntingtin (Hdh) gene, the huntingtin associated protein (Hap1) gene, and the huntingtin interacting protein (Hip1) gene to rat chromosomes 14, 10, and 12 by radiation hybrid mapping and fluorescent in situ hybridization
Cytogenetics and Cell Genetics 94: 101-104 (2001-01-01)

Mueller J.J.; Mueller E.C.; Montag T.; Zyto N.; Loeschner B.; Klein H.; Heineman U.; Otto A.
Characterization and crystallization of a novel Sarcocystis muris lectin, SML-2
Acta Crystallographica Section D 57 (7): 1042-1045 (2001-01-01)

Badock V.; Steinhusen U.; Bommert K.; Otto A.
Prefractionation of protein samples for proteome analysis using reversed-phase high-performance liquid chromatography
Electrophoresis 22 (14): 2856-2864 (2001-01-01)

Roemer I.; Vogel T.; Otto A.; Fichtner I.; Klose J.
Analysis of mouse beta-haptoglobin chain by lectin affinoblotting detection
Electrophoresis 22: 3038-3042 (2001-01-01)

Mueller E.C.; Lapko A.; Otto A.; Mueller J.J.; Ruckpaul K.; Heinemann U.
Covalently crosslinked complexes of bovine adrenodoxin with adrenodoxin reductase and cytochrome P450scc. Mass spectrometry and Edman degradation of complexes of the steroidogenic hydroxylase system.
European Journal of Biochemistry 268 (6): 1837-1843 (2001-01-01)

Mattow J.; Jungblut P.R.; Schaible U.E.; Mollenkopf H.J.; Lamer S.; Zimny-Arndt U.; Hagens K.; Mueller E.C.; Kaufmann S.H.E.
Identification of proteins from Mycobacterium tuberculosis missing in attenuated Mycobacterium bovis BCG strains
Electrophoresis 22: 2936-2946 (2001-01-01)

Mingot J.M.; Kostka S.; Kraft R.; Hartmann E.; Goerlich D.
Importin 13: a novel mediator of nuclear import and export
EMBO Journal 20: 3685-3694 (2001-01-01)

Muehlhaeusser P.; Mueller E.C.; Otto A.; Kutay U.
Multiple pathways contribute to nuclear import of core histones
EMBO Reports 2 (8): 690-696 (2001-01-01)

Jungblut P.R.; Mueller E.C.; Mattow J.; Kaufmann S.H.E.
Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rv not predicted by genomics
Infection and Immunity 69: 5905-5907 (2001-01-01)

Mattow J.; Jungblut P.R.; Mueller E.C.; Kaufmann S.H.E.
Identification of acidic, low molecular mass proteins of Mycobacterium tuberculosis strain H37Rv by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry
Proteomics 1 (4): 494-507 (2001-01-01)

Souto-Carneiro M.M.; Burkhardt H.; Mueller E.C.; Hermann R.; Otto A.; Kraetsch H.G.; Sack U.; Koenig A.; Heinegard D.; Muller-Hermelink H.K.; Krenn V.
Human monoclonal rheumatoid synovial B Lymphocyte hybridoma with a new disease-related specificity for cartilage oligomeric matrix protein
Journal of Immunology 166: 4202-4208 (2001-01-01)

Golbik R.; Naumann M.; Otto A.; Mueller E.C.; Behlke J.; Reuter R.; Kriegel T.M.
Regulation of phosphotransferase activity of hexokinase 2 from Saccharomyces cerevisiae by modification at serine-14
Biochemistry 40 (4): 1083-1090 (2001-01-01)

Urlaub H.; Raker V.A.; Kostka S.; Luehrmann R.
Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure
EMBO Journal 20 (1-2): 187-196 (2001-01-01)


Wanker E.E.
Protein aggregation in Huntington's and Parkinson's disease: implications for therapy
Molecular Medicine Today 6: 387-391 (2000-10-01)

Friedrich C.G.; Quentmeier A.; Bardischewsky F.; Rother D.; Kraft R.; Kostka S.; Prinz H.
Novel genes coding for lithotrophic sulfur oxidation of Paracoccus pantotrophus GB17
Journal of Bacteriology 182: 4677-4687 (2000-09-01)

Wanker E.E.
Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations
Biological Chemistry 381: 937-942 (2000-09-01)

Lipowsky G.; Bischoff F.R.; Schwarzmaier P.; Kraft R.; Kostka S.; Hartmann E.; Kutay U.; Goerlich D.
Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes
EMBO Journal 19: 4362-4371 (2000-08-15)

Kettritz R.; Xu Y.X.; Faass B.; Klein J.B.; Mueller E.C.; Otto A.; Busjahn A.; Luft F.C.; Haller H.
TNF-alpha-mediated neutrophil apoptosis involves Ly-GDI, a Rho GTPase regulator
Journal of Leukocyte Biology 68: 277-283 (2000-08-01)

Dong J.; Radau B.; Otto A.; Mueller E.C.; Lindschau C.; Westermann P.
Profilin I attached to the Golgi is required for the formation of constitutive transport vesicles at the trans-Golgi network
Biochimica et Biophysica Acta - Molecular Cell Research 1497 (2): 253-260 (2000-07-21)

Schwarz K.; van den Broek M.; Kostka S.; Kraft R.; Soza A.; Schmidtke G.; Kloetzel P.M.; Groettrup M.
Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope
Journal of Immunology 165 (2): 768-778 (2000-07-15)

Muchowski P.J.; Schaffar G.; Sittler A.; Wanker E.E.; Hayer-Hartl M.K.; Hartl F.U.
Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 7841-7846 (2000-07-05)

Radau B.; Otto A.; Mueller E.C.; Westermann P.
Protein kinase Calpha-dependent phosphorylation of golgi proteins
Electrophoresis 21: 2684-2687 (2000-07-01)

Schwarz K.; de Giuli R.; Schmidtke G.; Kostka S.; van den Broek M.; Kim K.B.; Crews C.M.; Kraft R.; Groettrup M.
The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses
Journal of Immunology 164 (12): 6147-6157 (2000-06-15)

Heiser V.; Scherzinger E.; Boeddrich A.; Nordhoff E.; Lurz R.; Schugardt N.; Lehrach H.; Wanker E.E.
Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy
Proceedings of the National Academy of Sciences of the United States of America 97 (12): 6739-6744 (2000-06-06)

Steffan J.S.; Kazantsev A.; Spasic-Boskovic O.; Greenwald M.; Zhu Y.Z.; Gohler H.; Wanker E.E.; Bates G.P.; Housman D.E.; Thompson L.M.
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
Proceedings of the National Academy of Sciences of the United States of America 97: 6763-6768 (2000-06-06)

Meyer H.A.; Grau H.; Kraft R.; Kostka S.; Prehn S.; Kalies K.U.; Hartmann E.
Mammalian Sec61 is associated with Sec62 and Sec63
Journal of Biological Chemistry 275 (19): 14550-14557 (2000-05-12)

Pevzner V.; Kraft R.; Kostka S.; Lipp M.
Phosphorylation of Oct-2 at sites located in the POU domain induces differential down-regulation of Oct-2 DNA-binding ability
Biochemical Journal 347 (1): 29-35 (2000-04-01)

Essmann F.; Wieder T.; Otto A.; Mueller E.C.; Doerken B.; Daniel P.T.
GDP dissociation inhibitor D4-GDI (Rho-GDI 2), but not the homologous Rho-GDI 1, is cleaved by caspase-3 during drug-induced apoptosis
Biochemical Journal 346 (3): 777-783 (2000-03-15)

Stohwasser R.; Giesebrecht J.; Kraft R.; Mueller E.C.; Haeusler K.G.; Kettenmann H.; Hanisch U.K.; Kloetzel P.M.
Biochemical analysis of proteasomes from mouse microglia: Induction of immunoproteasomes by interferon-gamma and lipopolysaccharide
Glia 29 (4): 355-365 (2000-02-15)

Quentmeier A.; Kraft R.; Kostka S.; Klockenkaemper R.; Friedrich C.G.
Characterization of a new type of sulfite dehydrogenase from Paracoccus pantotrophus GB17
Archives of Microbiology 173 (2): 117-125 (2000-02-01)

Cohen H.; Azriel A.; Cohen T.; Meraro D.; Hashmueli S.; Bech-Otschir D.; Kraft R.; Dubiel W.; Levi B.Z.
Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15) - A possible link between interferon regulatory factor signaling and the COP9/signalosome
Journal of Biological Chemistry 275 (50): 39081-39089 (2000-01-01)

Urlaub H.; Hartmuth K.; Kostka S.; Grelle G.; Luehrmann R.
A general approach for identification of RNA-Protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs) - Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPs
Journal of Biological Chemistry 275 (52): 41458-41468 (2000-01-01)

Mueller E.C.; Wittmann-Liebold B.; Otto A.
Investigation of apoptosis-involved processes by mass spectrometric identification of the apoptosis-associated proteins in IgM-induced burkitt lymphoma cells
Mass Spectrometry in Biology and Medicine : 271-287 (2000-01-01)


Starikov E.B.; Lehrach H.; Wanker E.E.
Folding of oligoglutamines: a theoretical approach based upon thermodynamics and molecular mechanics
Journal of Biomolecular Structure & Dynamics 17: 409-427 (1999-12-01)

Haase H.; Podzuweit T.; Lutsch G.; Hohaus A.; Kostka S.; Lindschau C.; Kott M.; Kraft R.; Morano I.
Signaling from beta-adrenoceptor to L-type calcium channel: identification of a novel cardiac protein kinase A target possessing similarities to AHNAK
FASEB Journal 13 (15): 2161-2172 (1999-12)

Schaefer H.; Bartels T.; Hahn G.; Otto A.; Burger R.
T-cell-activating monoclonal antibodies, reacting with both leukocytes and erythrocytes, recognize the guinea pig Thy-1 differentiation antigen: Characterization and cloning of guinea pig CD90
Cellular Immunology 197 (2): 116-128 (1999-11-01)

Leheste J.R.; Rolinski B.; Vorum H.; Hilpert J.; Nykjaer A.; Jacobsen C.; Aucouturier P.; Moskaug J.O.; Otto A.; Christensen E.I.; Willnow T.E.
Megalin knockout mice as an animal model of low molecular weight proteinuria
American Journal of Pathology 155 (4): 1361-1370 (1999-10-01)

Braun B.C.; Glickman M.; Kraft R.; Dahlmann B.; Kloetzel P.M.; Finley D.; Schmidt M.
The base of the proteasome regulatory particle exhibits chaperone-like activity
Nature Cell Biology 1 (4): 221-226 (1999-08-01)

Jungblut P.R.; Zimny-Arndt U.; Zeindl-Eberhart E.; Stulik J.; Koupilova K.; Pleissner K.P.; Otto A.; Mueller E.C.; Sokolowska-Koehler W.; Grabher G.; Stoeffler G.
Proteomics in human disease: cancer,heart and infectious diseases
Electrophoresis 20 (10): 2100-2110 (1999-07)

Richter R.; Hejazi M.; Kraft R.; Ziegler K.; Lockau W.
Cyanophycinase, a peptidase degrading the cyanobacterial reserve material multi-L-arginyl-poly-L-aspartic acid (cyanophycin) - Molecular cloning of the gene of Synechocystis sp PCC 6803, expression in Escherichia coli, and biochemical characterization of the purified enzyme
European Journal of Biochemistry 263: 163-169 (1999-07-01)

Hollenbach B.; Scherzinger E.; Schweiger K.; Lurz R.; Lehrach H.; Wanker E.E.
Aggregation of truncated GST-HD exon 1 fusion proteins containing normal range and expanded glutamine repeats
Philosophical Transactions of the Royal Society of London Series B Biological Sciences 354: 991-994 (1999-06-29)

Heidenreich O.; Neininger A.; Schratt G.; Zinck R.; Cahill M.A.; Engel K.; Kotlyarov A.; Kraft R.; Kostka S.; Gaestel M.; Nordheim A.
MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo
Journal of Biological Chemistry 274: 14434-14443 (1999-05-14)

Oleskina Y.P.; Yurina N.P.; Odintsova T.I.; Egorov T.A.; Otto A.; Wittmann-Liebold B.; Odintsova M.S.
Nucleoid proteins of pea chloroplasts: Detection of a protein homologous to ribosomal protein
Biochemistry and Molecular Biology International 47: 757-763 (1999-05-01)

Sathasivam K.; Hobbs C.; Turmaine M.; Mangiarini L.; Mahal A.; Bertaux F.; Wanker E.E.; Doherty P.; Davies S.W.; Bates G.P.
Formation of polyglutamine inclusions in non-CNS tissue
Human Molecular Genetics 8: 813-822 (1999-05-01)

Schmidt M.; Zantopf D.; Kraft R.; Kostka S.; Preissner R.; Kloetzel P.M.
Sequence information within proteasomal prosequences mediates efficient integration of beta-subunits into the 20 S proteasome complex
Journal of Molecular Biology 288: 117-128 (1999-04-23)

Scherzinger E.; Sittler A.; Schweiger K.; Heiser V.; Lurz R.; Hasenbank R.; Bates G.P.; Lehrach H.; Wanker E.E.
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology
Proceedings of the National Academy of Sciences of the United States of America 96 (8): 4604-4609 (1999-04-13)

Sieradzan K.A.; Mechan A.O.; Jones L.; Wanker E.E.; Nukina N.; Mann D.M.
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein
Experimental Neurology 156 (1): 92-99 (1999-03-01)

Mueller E.C.; Schuemann M.; Rickers A.; Bommert K.; Wittmann-Liebold B.; Otto A.
Study of Burkitt lymphoma cell line proteins by high resolution two-dimensional gel electrophoresis and nanoelectrospray mass spectrometry
Electrophoresis 20: 320-330 (1999-02-01)

Brockstedt E.; Otto A.; Rickers A.; Bommert K.; Wittmann-Liebold B.
Preparative high-resolution two-dimensional electrophoresis enables the identification of RNA polymerase B transcription factor 3 as an apoptosis-associated protein in the human BL60-2 Burkitt lymphoma cell line
Journal of Protein Chemistry 18 (2): 225-231 (1999-02)

Heuner K.; Choi B.K.; Schade R.; Moter A.; Otto A.; Goebel U.B.
Cloning and characterization of a gene (mspA) encoding the major sheath protein Treponema maltophilum ATCC51939(T)
Journal of Bacteriology 181: 1025-1029 (1999-02-01)

Koroljova O.V.; Stepanova E.V.; Gavrilova V.P.; Biniukov V.I.; Jaropolov A.I.; Varfolomeyev S.D.; Scheller F.W.; Makower A.; Otto A.
Laccase of Coriolus zonatus - Isolation, purification, and some physicochemical properties
Applied Biochemistry and Biotechnology 76: 115-127 (1999-02-01)

Hutloff A.; Dittrich A.M.; Beier K.C.; Eljaschewitsch B.; Kraft R.; Anagnostopoulos I.; Kroczek R.A.
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
Nature 397 (6716): 263-266 (1999-01-21)

Wanker E.E.; Scherzinger E.; Heiser V.; Sittler A.; Eickhoff H.; Lehrach H.
Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates
Methods in Enzymology 309: 375-386 (1999-01-01)

Davies S.W.; Sathasivam K.; Hobbs C.; Doherty P.; Mangiarini L.; Scherzinger E.; Wanker E.E.; Bates G.P.
Detection of polyglutamine aggregation in mouse models
Methods in Enzymology 309: 687-701 (1999-01-01)


Zechner U.; Scheel S.; Hemberger M.; Hopp M.; Haaf T.; Fundele R.; Wanker E.E.; Lehrach H.; Wedemeyer N.; Himmelbauer H.
Characterization of the mouse Src homology 3 domain gene Sh3d2c on Chr 7 demonstrates coexpression with huntingtin in the brain and identifies the processed pseudogene Sh3d2c-ps1 on Chr 2
Genomics 54: 505-510 (1998-12-15)

Brockstedt E.; Rickers A.; Kostka S.; Laubersheimer A.; Doerken B.; Wittmann-Liebold B.; Bommert K.; Otto A.
Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line - cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3
Journal of Biological Chemistry 273 (43): 28057-28064 (1998-10-23)

Sittler A.; Walter S.; Wedemeyer N.; Hasenbank R.; Scherzinger E.; Eickhoff H.; Bates G.P.; Lehrach H.; Wanker E.E.
SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates
Molecular Cell 2 (4): 427-436 (1998-10)

Jungblut P.R.; Otto A.; Favor J.; Loewe M.; Mueller E.C.; Kastner M.; Sperling K.; Klose J.
Identification of mouse crystallins in 2D protein patterns by sequencing and mass spectrometry. Application to cataract mutants
FEBS Letters 435: 131-137 (1998-09-18)

Thiede B.; Urlaub H.; Neubauer H.; Grelle G.; Wittmann-Liebold B.
Precise determination of RNA-protein contact sites in the 50 S ribosomal subunit of Escherichia coli
Biochemical Journal 334 P.1: 39-42 (1998-08-15)

Bates G.P.; Mangiarini L.; Wanker E.E.; Davies S.W.
Polyglutamine expansion and Huntington's disease
Biochemical Society Transactions 26: 471-475 (1998-08-01)

Otto A.; Mueller E.C.; Brockstedt E.; Schumann M.; Rickers A.; Bommert K.; Wittmann-Liebold B.
High performance two dimensional gel electrophoresis and nanoelectrospray mass spectrometry as powerful tool to study apoptosis-associated processes in a Burkitt lymphoma cell line
Journal of Protein Chemistry 17: 564-565 (1998-08-01)

Saalbach A.; Kraft R.; Herrmann K.; Haustein U.F.; Anderegg U.
The monoclonal antibody AS02 recognizes a protein on human fibroblasts being highly homologous to Thy-1
Archives of Dermatological Research 290: 360-366 (1998-07-01)

Tait D.; Riccio M.; Sittler A.; Scherzinger E.; Santi S.; Ognibene A.; Maraldi N.M.; Lehrach H.; Wanker E.E.
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
Human Molecular Genetics 7 (6): 991-997 (1998-06)

Georgalis Y.; Starikov E.B.; Hollenbach B.; Lurz R.; Scherzinger E.; Saenger W.; Lehrach H.; Wanker E.E.
Huntingtin aggregation monitored by dynamic light scattering
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 6118-6121 (1998-05-26)

Bertaux F.; Sharp A.H.; Ross C.A.; Lehrach H.; Bates G.P.; Wanker E.E.
HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice
FEBS Letters 426: 229-232 (1998-04-17)

Seeger M.; Kraft R.; Ferrell K.; Bech-Otschir D.; Dumedey R.; Schade R.; Gordon C.; Naumann M.; Dubiel W.
A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
FASEB Journal 12 (6): 469-478 (1998-04-01)

Behlke J.; Heidrich K.; Naumann M.; Mueller E.C.; Otto A.; Reuter R.; Kriegel T.
Hexokinase 2 from Saccharomyces cerevisiae: regulation of oligomeric structure by in vivo phosphorylation at serine-14
Biochemistry 37: 11989-11995 (1998-01-01)

Boettger M.; Zaitsev S.V.; Otto A.; Haberland A.; Vorob'ev V.I.
Acid nuclear extracts as mediators of gene transfer and expression
Biochimica et Biophysica Acta 1395: 78-87 (1998-01-01)

Himmelbauer H.; Wedemeyer N.; Haaf T.; Wanker E.E.; Schalkwyk L.C.; Lehrach H.
IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse chromosome 5
Mammalian Genome 9: 26-31 (1998-01-01)

Rickers A.; Brockstedt E.; Mapara M.Y.; Otto A.; Doerken B.; Bommert K.
Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL 60 Burkitt lymphoma cells
European Journal of Immunology 28: 296-304 (1998-01-01)

Hayess K.; Kraft R.; Sachsinger J.; Janke J.; Jandrig B.; Beckmann G.; Rohde K.; Benndorf R.
Mammalian protein homologous to VAT-1 of torpedo californica: isolation from Ehrlich Ascites Tumor cells, biochemical characterization and organization of its gene
Journal of Cellular Biochemistry 69: 304-315 (1998-01-01)


Wedemeyer N.; Peoples R.; Himmelbauer H.; Lehrach H.; Francke U.; Wanker E.E.
Localization of the human HIP1 gene close to the elastin (ELN) locus on 7q11.23
Genomics 46: 313-315 (1997-12-01)

Scherzinger E.; Lurz R.; Turmaine M.; Mangiarini L.; Hollenbach B.; Hasenbank R.; Bates G.P.; Davies S.W.; Lehrach H.; Wanker E.E.
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
Cell 90 (3): 549-558 (1997-08-08)

Davies S.W.; Turmaine M.; Cozens B.A.; DiFiglia M.; Sharp A.H.; Ross C.A.; Scherzinger E.; Wanker E.E.; Mangiarini L.; Bates G.P.
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
Cell 90 (3): 537-548 (1997-08-08)

Wanker E.E.; Rovira C.; Scherzinger E.; Hasenbank R.; Walter S.; Tait D.; Colicelli J.; Lehrach H.
HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system
Human Molecular Genetics 6 (3): 487-495 (1997-03-01)

Schumacher S.; Volkmer H.; Buck F.; Otto A.; Tarnok A.; Roth S.; Rathjen F.G.
Chicken acidic leucine-rich EGF-like domain containing brain protein (CALEB), a neural member of the EGF family of differentiation factors, is implicated in neurite formation
Journal of Cell Biology 136 (4): 895-906 (1997-02-24)

Scheler C.; Mueller E.C.; Stahl J.; Mueller-Werdan U.; Salnikov J.; Jungblut P.
Identification and characterization of heat shock protein 27 protein species in human myocardial two-dimensional electrophoresis patterns
Electrophoresis 18: 2823-2831 (1997-01-01)

Kutay U.; Bischoff F.R.; Kostka S.; Kraft R.; Goerlich D.
Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor
Cell 90: 1061-1071 (1997-01-01)

Dorner B.; Mueller S.; Entschladen F.; Schroeder J.M.; Frankel P.; Kraft R.; Friedl P.; Clarklewis I.; Kroczek R.A.
Purification, structural analysis, and function of natural atac, a cytokine secreted by cd8(+) T cells
Journal of Biological Chemistry 272: 8817-8823 (1997-01-01)


Wanker E.E.; Klingsbichel E.; Schwab H.
Efficient secretion of Bacillus subtilis levanase by Saccharomyces cerevisiae
Gene 161: 45-49 (1995-08-08)

Wanker E.E.; Sun Y.; Savitz A.J.; Meyer D.I.
Functional characterization of the 180-kD ribosome receptor in vivo
Journal of Cell Biology 130 (1): 29-39 (1995-07)

Wanker E.E.; Huber A.; Schwab H.
Purification and characterization of the Bacillus subtilis levanase produced in Escherichia coli
Applied and Environmental Microbiology 61: 1953-1958 (1995-05-01)

Wanker E.E.; Leer R.J.; Pouwels P.H.; Schwab H.
Expression of Bacillus subtilis levanase gene in Lactobacillus plantarum and Lactobacillus casei
Applied Microbiology and Biotechnology 43: 297-303 (1995-05-01)


Wanker E.E.; Schorgendorfer K.; Schwab H.
Expression of the Bacillus subtilis levanase gene in Escherichia coli and Saccharomyces cerevisiae
Journal of Biotechnology 18: 243-254 (1991-05-01)