microRNA and Molecular Mechanisms of Metabolic Diseases

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Our group is focused on microRNA-mediated gene regulation in the pancreatic β-cell and how these mechanisms may be impacted by changes in nutrient intake or sensing. Current investigations emphasize the identification of factors which regulate microRNA expression according to changes in insulin sensitivity and will continue to address novel aspects of metabolism and islet biology by pursuing mechanisms identified through the study of non-coding RNAs.