Head of the Group
Prof. Dr. Jeanette Schulz-Menger
Differentiation of Myocardial Injury Applying Cardiovascular Magnetic Resonance
The diagnosis of myocarditis and the assessment of myocardial tissue changes during follow-up is a challenging task in cardiovascular research and clinical cardiology. The group of cardiac MRI developed a new pulse sequence, which allows to directly quantify magnetic relaxation properties of the myocardium quantitatively. This technique has also been used to address the diagnostic uncertainty in cardiac sarcoidosis. In addition, the need to differentiate acute from chronic and irreversible myocardial injury has been addressed: The group has shown, that combined sequences offer the capability to differentiate acute from chronic myocardial infarction and to identify the impact of reperfusion injury after acute myocardial infarction. The quantification of myocardial oxygenation detectable by blood-oxygen-level-dependent (BOLD) is a crucial step for the detection of ischemia without the use of contrast media. The BOLD technique, so far used in brain imaging, was established for the detection of myocardial ischemia. BOLD MRI may be a useful adjunct in assessing endothelial dysfunction.