Publications



2017

van der Graaf A.M.; Toering T.J.; van der Wiel M.W.K.; Frenay A.R.S.; Wallukat G.; Dechend R.; Navis G.; Groen H.; Lely A.T.; Faas M.M.
Angiotensin II responsiveness after preeclampsia: translational data from an experimental rat model and early-onset human preeclampsia
Journal of Hypertension 35 (12): 2468-2478 (2017-12)



Wilck N.; Matus M.G.; Kearney S.M.; Olesen S.W.; Forslund K.; Bartolomaeus H.; Haase S.; Maehler A.; Balogh A.; Marko L.; Vvedenskaya O.; Kleiner F.H.; Tsvetkov D.; Klug L.; Costea P.I.; Sunagawa S.; Maier L.; Rakova N.; Schatz V.; Neubert P.; Fraetzer C.; Krannich A.; Gollasch M.; Grohme D.A.; Corte-Real B.F.; Gerlach R.G.; Basic M.; Typas A.; Wu C.; Titze J.M.; Jantsch J.; Boschmann M.; Dechend R.; Kleinewietfeld M.; Kempa S.; Bork P.; Linker R.A.; Alm E.J.; Mueller D.N.
Salt-responsive gut commensal modulates TH17 axis and disease
Nature 551 (7682): 585-589 (2017-11-30)



Zadora J.; Singh M.; Herse F.; Przybyl L.; Haase N.; Golic M.; Yung H.W.; Huppertz B.; Cartwright J.E.; Whitley G.S.; Johnsen G.M.; Levi G.; Isbruch A.; Schulz H.; Luft F.C.; Mueller D.N.; Staff A.C.; Hurst L.D.; Dechend R.; Izsvak Z.
Disturbed placental imprinting in preeclampsia leads to altered expression of DLX5, a human-specific early trophoblast marker
Circulation 136 (19): 1824-1839 (2017-11-07)



Ibrahim T.; Przybyl L.; Harmon A.C.; Amaral L.M.; Faulkner J.L.; Cornelius D.; Cunningham M.W.; Huenig T.; Herse F.; Wallukat G.; Dechend R.; LaMarca B.
Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy
American Journal of Reproductive Immunology 78 (5): e12724 (2017-11)



Gauster M.; Maninger S.; Siwetz M.; Deutsch A.; El-Heliebi A.; Kolb-Lenz D.; Hiden U.; Desoye G.; Herse F.; Prokesch A.
Downregulation of p53 drives autophagy during human trophoblast differentiation
Cellular and Molecular Life Sciences : (2017-10-27)



Hewing B.; Ludwig A.; Dan C.; Poetzsch M.; Hannemann C.; Petry A.; Lauer D.; Goerlach A.; Kaschina E.; Mueller D.N.; Baumann G.; Stangl V.; Stangl K.; Wilck N.
Immunoproteasome subunit {beta}5i/LMP7-deficiency in atherosclerosis
Scientific Reports 7 (1): 13342 (2017-10-17)



Moe K.; Heidecke H.; Dechend R.; Staff A.C.
Dysregulation of circulating autoantibodies against VEGF-A, VEGFR-1 and PlGF in preeclampsia - a role in placental and vascular health?
Pregnancy Hypertension 10: 83-89 (2017-10)



Sugulle M.; Heidecke H.; Maschke U.; Herse F.; Danser A.H.J.; Mueller D.N.; Staff A.C.; Dechend R.
Soluble (pro)renin receptor in preeclampsia and diabetic pregnancies
Journal of the American Society of Hypertension 11 (10): 644-652 (2017-10)



Hammer A.; Schliep A.; Joerg S.; Haghikia A.; Gold R.; Kleinewietfeld M.; Mueller D.N.; Linker R.A.
Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation
Journal of Neuroinflammation 14 (1): 184 (2017-09-12)



Giil L.M.; Vedeler C.A.; Kristoffersen E.K.; Nordrehaug J.E.; Heidecke H.; Dechend R.; Schulze-Forster K.; Muller D.N.; von Goetze V.S.; Cabral-Marques O.; Riemekasten G.; Vogelsang P.; Nygaard S.; Lund A.; Aarsland D.
Antibodies to signaling molecules and receptors in Alzheimer's disease are associated with psychomotor slowing, depression, and poor visuospatial function
Journal of Alzheimer's Disease 59 (3): 929-939 (2017-07-29)



Kuehnel E.; Kleff V.; Stojanovska V.; Kaiser S.; Waldschuetz R.; Herse F.; Ploesch T.; Winterhager E.; Gellhaus A.
Placental-specific overexpression of sFlt-1 alters trophoblast differentiation and nutrient transporter expression in an IUGR mouse model
Journal of Cellular Biochemistry 118 (6): 1316-1329 (2017-06)



Prokesch A.; Blaschitz A.; Bauer T.; Moser G.; Hiden U.; Zadora J.; Dechend R.; Herse F.; Gauster M.
Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-{alpha} in a gestational age-dependent manner
Histochemistry and Cell Biology 147 (6): 695-705 (2017-06)



Haase N.; Rueder C.; Haase H.; Kamann S.; Kouno M.; Morano I.; Dechend R.; Zohlnhoefer D.; Haase T.
Protective function of ahnak1 in vascular healing after wire injury
Journal of Vascular Research 54 (3): 131-142 (2017-05)



Kitada K.; Daub S.; Zhang Y.; Klein J. D.; Nakano D.; Pedchenko T.; Lantier L.; LaRocque L.M.; Marton A.; Neubert P.; Schroeder A.; Rakova N.; Jantsch J.; Dikalova A.E.; Dikalov S.I.; Harrison D.G.; Mueller D.N.; Nishiyama A.; Rauh M.; Harris R. C.; Luft F.C.; Wassermann D.H.; Sands J.M.; Titze J.
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation
Journal of Clinical Investigation 127 (5): 1944-1959 (2017-05-01)



Schlieper G.; Schwenger V.; Remppis A.; Keller T.; Dechend R.; Massberg S.; Baldus S.; Weinreich T.; Hetzel G.; Floege J.; Mahfoud F.; Fliser D.
Antikoagulation bei Patienten mit chronischer Niereninsuffizienz : Empfehlungen der Arbeitsgemeinschaft "Herz-Niere" der Deutschen Gesellschaft fuer Kardiologie - Herz- und Kreislaufforschung und der Deutschen Gesellschaft fuer Nephrologie [Anticoagulation in patients with chronic kidney disease : Recommendations from the working group "Heart-Kidney" of the German Cardiac Society and the German Society of Nephrology]
Internist 58 (5): 512-521 (2017-05)



Ehrlich L.; Hoeller A.; Golic M.; Herse F.; Perschel F.H.; Henrich W.; Dechend R.; Huppertz B.; Verlohren S.
Increased placental sFlt-1 but unchanged PlGF expression in late-onset preeclampsia
Hypertension in Pregnancy 36 (2): 175-185 (2017-05)



Hoeller A.; Ehrlich L.; Golic M.; Herse F.; Perschel F.H.; Siwetz M.; Henrich W.; Dechend R.; Huppertz B.; Verlohren S.
Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies
Hypertension in Pregnancy 36 (2): 151-160 (2017-05)



Lankhorst S.; Severs D.; Marko L.; Rakova N.; Titze J.; Mueller D.N.; Danser A.H.J.; van den Meiracker A.H.
Salt sensitivity of angiogenesis inhibition-induced blood pressure rise: role of interstitial sodium accumulation?
Hypertension 69 (5): 919-926 (2017-05)



Wilck N.; Fechner M.; Dan C.; Stangl V.; Stangl K.; Ludwig A.
The effect of low-dose proteasome inhibition on pre-existing atherosclerosis in LDL receptor-deficient mice
International Journal of Molecular Sciences 18 (4): 781 (2017-04-07)



Nikpey E.; Karlsen T.V.; Rakova N.; Titze J.M.; Tenstad O.; Wiig H.
High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph
Hypertension 69 (4): 660-668 (2017-04)



Limmroth V.; Ziemssen T.; Lang M.; Richter S.; Wagner B.; Haas J.; Schmidt S.; Gerbershagen K.; Lassek C.; Klotz L.; Hoffmann O.; Albert C.; Schuh K.; Baier-Ebert M.; Wendt G.; Schieb H.; Hoyer S.; Dechend R.; Haverkamp W.
Electrocardiographic assessments and cardiac events after fingolimod first dose a comprehensive monitoring study
BMC Neurology 17 (1): 11 (2017-01-18)



Faulkner J.L.; Amaral L.M.; Cornelius D.C.; Cunningham M.W.; Ibrahim T.; Heep A.; Campbell N.; Usry N.; Wallace K.; Herse F.; Dechend R.; LaMarca B.D.
Vitamin D supplementation reduces some AT1-AA induced downstream targets implicated in preeclampsia including hypertension
American Journal of Physiology Regulatory Integrative and Comparative Physiology 312 (1): R125-R131 (2017-01-01)



Reichhart N.; Crespo-Garcia S.; Haase N.; Golic M.; Skosyrski S.; Ruebsam A.; Herrspiegel C.; Kociok N.; Alenina N.; Bader M.; Dechend R.; Strauss O.; Joussen A.M.
The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown
Diabetologia 60 (1): 202-211 (2017-01)



2016

Hammer A.; Yang G.; Friedrich J.; Kovacs A.; Lee D.H.; Grave K.; Joerg S.; Alenina N.; Grosch J.; Winkler J.; Gold R.; Bader M.; Manzel A.; Rump L.C.; Mueller D.N.; Linker R.A.; Stegbauer J.
Role of the receptor Mas in macrophage-mediated inflammation in vivo
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114 (2016-12-06)



Joerg S.; Grohme D.A.; Erzler M.; Binsfeld M.; Haghikia A.; Mueller D.N.; Linker R.A.; Kleinewietfeld M.
Environmental factors in autoimmune diseases and their role in multiple sclerosis
Cellular and Molecular Life Sciences 73 (24): 4611-4622 (2016-12)



Cornelius D.C.; Amaral L.M.; Wallace K.; Campbell N.; Thomas A.J.; Scott J.; Herse F.; Wallukat G.; Dechend R.; LaMarca B.
Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy
American Journal of Physiology Regulatory Integrative and Comparative Physiology 311 (6): R1192-R1199 (2016-12-01)



Cunningham M.W.; Williams J.M.; Amaral L.; Usry N.; Wallukat G.; Dechend R.; LaMarca B.
Agonistic autoantibodies to the angiotensin II type 1 receptor enhance angiotensin II-induced renal vascular sensitivity and reduce renal function during pregnancy
Hypertension 68 (5): 1308-1313 (2016-11)



Andersen L.B.; Dechend R.; Karumanchi S.A.; Nielsen J.; Joergensen J.S.; Jensen T.K.; Christesen H.T.
Early pregnancy angiogenic markers and spontaneous abortion: an Odense Child Cohort study
American Journal of Obstetrics and Gynecology 215 (5): 594.e1-594.e11 (2016-11)



Golic M.; Luft F.C.; Dechend R.
Tumor necrosis factor-{alpha}, uterine natural killer cells, and pregnancy
Hypertension 68 (5): 1108-1109 (2016-11)



Manolis A.J.; Poulimenos L.E.; Ambrosio G.; Kallistratos M.S.; Lopez-Sendon J.; Dechend R.; Mancia G.; Camm A.J.
Medical treatment of stable angina: a tailored therapeutic approach
International Journal of Cardiology 220: 445-453 (2016-10-01)



Yung H.W.; Alaes-Katjavivi P.; Jones C.J.P.; El-Bacha T.; Golic M.; Staff A.C.; Burton G.J.
Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants
Diabetologia 59 (10): 2240-2250 (2016-10)



Golic M.; Haase N.; Herse F.; Wehner A.; Vercruysse L.; Pijnenborg R.; Balogh A.; Saether P.C.; Dissen E.; Luft F.C.; Przybyl L.; Park J.K.; Alnaes-Katjavivi P.; Staff A.C.; Verlohren S.; Henrich W.; Muller D.N.; Dechend R.
Natural killer cell reduction and uteroplacental vasculopathy
Hypertension 68 (4): 964-973 (2016-10)



Kistner I.; Zeymer U.; Dechend R.; Hagedorn I.; Riemer T.; Bramlage P.; Pittrow D.; Senges J.; Schmieder R.E.
Benefits and risks of aliskiren treatment in patients with type 2 diabetes: analyses of the 3A registry
Journal of Clinical Hypertension 18 (10): 1045-1053 (2016-10)



Rohr I.; Braicu E.I.; En-Nia A.; Heinrich M.; Richter R.; Chekerov R.; Dechend R.; Heidecke H.; Dragun D.; Schaefer R.; Gorny X.; Lindquist J.; Brandt S.; Sehouli J.; Mertens P.R.
Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: a study by the Tumor Bank Ovarian Cancer (TOC)
Cytokine 85: 157-164 (2016-09)



Andersen L.B.; Jorgensen J.S.; Herse F.; Andersen M.S.; Christesen H.T.; Dechend R.
The association between angiogenic markers and fetal sex: implications for preeclampsia research
Journal of Reproductive Immunology 117: 24-29 (2016-09)



Marko L.; Vigolo E.; Hinze C.; Park J.K.; Roel G.; Balogh A.; Choi M.; Wuebken A.; Cording J.; Blasig I.E.; Luft F.C.; Scheidereit C.; Schmidt-Ott K.M.; Schmidt-Ullrich R.; Mueller D.N.
Tubular epithelial NF-{kappa}B activity regulates ischemic AKI
Journal of the American Society of Nephrology 27 (9): 2658-2669 (2016-09)



Hytoenen J.; Leppaenen O.; Braesen J.H.; Schunck W.H.; Mueller D.; Jung F.; Mrowietz C.; Jastroch M.; von Bergwelt-Baildon M.; Kappert K.; Heuser A.; Drenckhahn J.D.; Pieske B.; Thierfelder L.; Ylae-Herttuala S.; Blaschke F.
Activation of peroxisome proliferator-activated receptor-{delta} as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis
Arteriosclerosis Thrombosis and Vascular Biology 36 (8): 1534-1548 (2016-08)



Tholl U.; Lueders S.; Bramlage P.; Dechend R.; Eckert S.; Mengden T.; Nuernberger J.; Sanner B.; Anlauf M.
The German Hypertension League (Deutsche Hochdruckliga) Quality Seal Protocol for blood pressure-measuring devices: 15-year experience and results from 105 devices for home blood pressure control
Blood Pressure Monitoring 21 (4): 197-205 (2016-08)



Andersen L.B.; Dechend R.; Jorgensen J.S.; Luef B.M.; Nielsen J.; Barington T.; Christesen H.T.
Prediction of preeclampsia with angiogenic biomarkers. Results from the prospective Odense Child Cohort
Hypertension in Pregnancy 35 (3): 405-419 (2016-08)



Bjerre A.; Tangeraas T.; Heidecke H.; Dragun D.; Dechend R.; Staff A.C.
Angiotensin II type 1 receptor antibodies in childhood kidney transplantation
Pediatric Transplantation 20 (5): 627-632 (2016-08)



Zeymer U.; Dechend R.; Riemer T.; Deeg E.; Senges J.; Pittrow D.; Schmieder R.
Two-year outcomes of patients treated with aliskiren under clinical practice conditions: non-interventional prospective study
Journal of Clinical Hypertension 18 (7): 647-654 (2016-07)



Andersen L.B.; Golic M.; Przybyl L.; Sorensen G.L.; Jorgensen J.S.; Fruekilde P.; von Versen-Hoeynck F.; Herse F.; Hojskov C.S.; Dechend R.; Christesen H.T.; Haase N.
Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia
Journal of the American Society of Hypertension 10 (7): 597-607.e1 (2016-07)



Reichhart N.; Haase N.; Crespo-Garcia S.; Skosyrski S.; Herrspiegel C.; Kociok N.; Fuchshofer R.; Dillinger A.; Poglitsch M.; Muller D.N.; Joussen A.M.; Luft F.C.; Dechend R.; Strauss O.
Hypertensive retinopathy in a transgenic angiotensin-based model
Clinical Science 130 (13): 1075-1088 (2016-07-01)



Przybyl L.; Haase N.; Golic M.; Rugor J.; Solano M.E.; Arck P.C.; Gauster M.; Huppertz B.; Emontzpohl C.; Stoppe C.; Bernhagen J.; Leng L.; Bucala R.; Schulz H.; Heuser A.; Weedon-Fekjaer S.; Johnsen G.M.; Peetz D.; Luft F.C.; Staff A.C.; Mueller D.N.; Dechend R.; Herse F.
CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia
Circulation Research 119 (1): 55-68 (2016-06-24)



Marko L.; Szijarto I.A.; Filipovic M.R.; Kassmann M.; Balogh A.; Park J.K.; Przybyl L.; N'diaye G.; Kraemer S.; Anders J.; Ishii I.; Mueller D.N.; Gollasch M.
Role of cystathionine gamma-lyase in immediate renal impairment and inflammatory response in acute ischemic kidney injury
Scientific Reports 6: 27517 (2016-06-08)



Haase N.; Golic M.; Herse F.; Rugor J.; Linz D.; Solano M.E.; Mueller D.N.; Dechend R.
Relaxin treatment in an Ang-II-Based transgenic reeclamptic-rat model
PLoS ONE 11 (3): e0150743 (2016-03-10)



Faulkner J.L.; Cornelius D.C.; Amaral L.M.; Harmon A.C.; Cunningham M.W.; Darby M.M.; Ibrahim T.; Thomas D.S.; Herse F.; Wallukat G.; Dechend R.; LaMarca B.
Vitamin D supplementation improves pathophysiology in a rat model of preeclampsia
American Journal of Physiology Regulatory Integrative and Comparative Physiology 310 (4): R346-R354 (2016-02-15)



Kammerer R.; Herse F.; Zimmermann W.
Convergent evolution within CEA gene families in mammals: hints for species-specific selection pressures
Evolutionary Biology : Convergent Evolution, Evolution of Complex Traits, Concepts and Methods : 37-53 (2016)



Kreienbring K.; Franz A.; Richter R.; Dragun D.; Heidecke H.; Dechend R.; Mueller D.N.; Sehouli J.; Braicu E.I.
Predictive and prognostic value of sPRR in patients with primary epithelial ovarian cancer
Analytical Cellular Pathology 2016: 6845213 (2016)



2015

Cornelius D.C.; Castillo J.; Porter J.; Amaral L.M.; Campbell N.; Paige A.; Thomas A.J.; Harmon A.; Cunningham M.W.; Wallace K.; Herse F.; Wallukat G.; Dechend R.; LaMarca B.D.
Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4+ T lymphocytes from RUPP rats
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309 (10): R1243-R1250 (2015-11-15)



Binger K.J.; Gebhardt M.; Heinig M.; Rintisch C.; Schroeder A.; Neuhofer W.; Hilgers K.; Manzel A.; Schwartz C.; Kleinewietfeld M.; Voelkl J.; Schatz V.; Linker R.A.; Lang F.; Voehringer D.; Wright M.D.; Hubner N.; Dechend R.; Jantsch J.; Titze J.; Mueller D.N.
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages
Journal of Clinical Investigation 125 (11): 4223-4238 (2015-11-02)



Pulgar V.M.; Yamaleyeva L.M.; Varagic J.; McGee C.; Bader M.; Dechend R.; Brosnihan K.B.
Functional changes in the uterine artery precede the hypertensive phenotype in a transgenic model of hypertensive pregnancy
American Journal of Physiology Endocrinology and Metabolism 309 (9): E811-E817 (2015-11-01)



Haghikia A.; Joerg S.; Duscha A.; Berg J.; Manzel A.; Waschbisch A.; Hammer A.; Lee D.H.; May C.; Wilck N.; Balogh A.; Ostermann A.I.; Schebb N.H.; Akkad D.A.; Grohme D.A.; Kleinewietfeld M.; Kempa S.; Thoene J.; Demir S.; Mueller D.N.; Gold R.; Linker R.A.
Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine
Immunity 43 (4): 817-829 (2015-10-20)



Cornelius D.C.; Amaral L.M.; Harmon A.; Wallace K.; Thomas A.J.; Campbell N.; Scott J.; Herse F.; Haase N.; Moseley J.; Wallukat G.; Dechend R.; LaMarca B.
An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309 (8): R884-R891 (2015-10-15)



Leslie K.; Whitley G.S.J.; Herse F.; Dechend R.; Ashton S.V.; Laing K.; Thilaganathan B.; Cartwright J.E.
Increased apoptosis, altered oxygen signaling, and antioxidant defenses in first-trimester pregnancies with high-resistance uterine artery blood flow
American Journal of Pathology 185 (10): 2731-2741 (2015-10)



Harmon A.; Cornelius D.; Amaral L.; Paige A.; Herse F.; Ibrahim T.; Wallukat G.; Faulkner J.; Moseley J.; Dechend R.; LaMarca B.
IL-10 supplementation increases Tregs and decreases hypertension in the RUPP rat model of preeclampsia
Hypertension in Pregnancy 34 (3): 291-306 (2015-08)



Geisberger S.; Maschke U.; Gebhardt M.; Kleinewietfeld M.; Manzel A.; Linker R.A.; Chidgey A.; Dechend R.; Nguyen G.; Daumke O.; Muller D.N.; Wright M.D.; Binger K.J.
New role for the (pro)renin receptor in T cell development
Blood 126 (4): 504-507 (2015-07-23)



Schlembach D.; Homuth V.; Dechend R.
Treating hypertension in pregnancy
Current Hypertension Reports 17: 63 (2015-07)



Przybyl L.; Ibrahim T.; Haase N.; Golic M.; Rugor J.; Luft F.C.; Bendix I.; Serdar M.; Wallukat G.; Staff A.C.; Mueller D.N.; Huenig T.; Felderhoff-Mueser U.; Herse F.; LaMarca B.; Dechend R.
Regulatory T cells ameliorate intrauterine growth retardation in a transgenic rat model for preeclampsia
Hypertension 65 (6): 1298-1306 (2015-06)



Kankuri E.; Mervaala E.E.; Storvik M.; Ahola A.M.J.; Levijoki J.; Mueller D.N.; Finckenberg P.; Mervaala E.M.
Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation
Clinical Science 128 (11): 735-747 (2015-06-01)



Siwetz M.; Sundl M.; Kolb D.; Hiden U.; Herse F.; Huppertz B.; Gauster M.
Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast
Histochemistry and Cell Biology 143 (6): 565-574 (2015-06)



Friedrich S.; Zeymer U.; Dechend R.; Hagedorn I.; Riemer T.; Zemmrich C.; Bramlage P.; Pittrow D.; Senges J.; Schmieder R.E.
The impact of age on the benefits and risks of aliskiren treatment: analyses of the 3A registry
Journal of Human Hypertension 29 (5): 316-323 (2015-05)



Siwetz M.; Dieber-Rotheneder M.; Cervar-Zivkovic M.; Kummer D.; Kremshofer J.; Weiss G.; Herse F.; Huppertz B.; Gauster M.
Placental fractalkine is up-regulated in severe early-onset preeclampsia
American Journal of Pathology 185 (5): 1334-1343 (2015-05)



Walentin K.; Hinze C.; Werth M.; Haase N.; Varma S.; Morell R.; Aue A.; Poetschke E.; Warburton D.; Qiu A.; Barasch J.; Purfuerst B.; Dieterich C.; Popova E.; Bader M.; Dechend R.; Staff A.C.; Yurtdas Z.Y.; Kilic E.; Schmidt-Ott K.M.
A Grhl2-dependent gene network controls trophoblast branching morphogenesis
Development 142 (6): 1125-1136 (2015-03-15)



Jantsch J.; Schatz V.; Friedrich D.; Schroeder A.; Kopp C.; Siegert I.; Maronna A.; Wendelborn D.; Linz P.; Binger K.J.; Gebhardt M.; Heinig M.; Neubert P.; Fischer F.; Teufel S.; David J.P.; Neufert C.; Cavallaro A.; Rakova N.; Kueper C.; Beck F.X.; Neuhofer W.; Muller D.N.; Schuler G.; Uder M.; Bogdan C.; Luft F.C.; Titze J.
Cutaneous Na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense
Cell Metabolism 21 (3): 493-501 (2015-03-03)



Binger K.J.; Linker R.A.; Muller D.N.; Kleinewietfeld M.
Sodium chloride, SGK1, and Th17 activation
Pfluegers Archiv European Journal of Physiology 467 (3): 543-550 (2015-03)



Andersen L.B.; Frederiksen-Moller B.; Work Havelund K.; Dechend R.; Jorgensen J.S.; Jensen B.L.; Nielsen J.; Lykkedegn S.; Barington T.; Christesen H.T.
Diagnosis of preeclampsia with soluble Fms-like tyrosine kinase 1/placental growth factor ratio: an inter-assay comparison
Journal of the American Society of Hypertension 9 (2): 86-96 (2015-02)



Andersen L.B.; Przybyl L.; Haase N.; von Versen-Hoeynck F.; Qadri F.; Jorgensen J.S.; Sorensen G.L.; Fruekilde P.; Poglitsch M.; Szijarto I.; Gollasch M.; Peters J.; Muller D.N.; Christesen H.T.; Dechend R.
Vitamin D depletion aggravates hypertension and target-organ damage
Journal of the American Heart Association 4 (2): e001417 (2015-02)



Linz D.; Hohl M.; Schuetze J.; Mahfoud F.; Speer T.; Linz B.; Huebschle T.; Juretschke H.P.; Dechend R.; Geisel J.; Ruetten H.; Boehm M.
Progression of kidney injury and cardiac remodeling in obese spontaneously hypertensive rats: the role of renal sympathetic innervation
American Journal of Hypertension 28 (2): 256-265 (2015-02)



Dahlmann A.; Doerfelt K.; Eicher F.; Linz P.; Kopp C.; Moessinger I.; Horn S.; Bueschges-Seraphin B.; Wabel P.; Hammon M.; Cavallaro A.; Eckardt K.U.; Kotanko P.; Levin N.W.; Johannes B.; Uder M.; Luft F.C.; Mueller D.N.; Titze J.M.
Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients
Kidney International 87 (2): 434-441 (2015-02)



Blois S.M.; Dechend R.; Barrientos G.; Staff A.C.
A potential pathophysiological role for galectins and the renin-angiotensin system in preeclampsia
Cellular and Molecular Life Sciences 72 (1): 39-50 (2015-01)



Linz P.; Santoro D.; Renz W.; Rieger J.; Ruehle A.; Ruff J.; Deimling M.; Rakova N.; Muller D.N.; Luft F.C.; Titze J.; Niendorf T.
Skin sodium measured with (23) Na MRI at 7.0 T
NMR in Biomedicine 28 (1): 54-62 (2015-01)



2014

Tank J.; da Costa-Goncalves A.C.; Kamer I.; Qadri F.; Ubhi K.; Rockenstein E.; Diedrich A.; Masliah E.; Gross V.; Jordan J.
Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes
Physiological Reports 2 (11): e12209 (2014-11-26)



Wilck N.; Ludwig A.
Targeting the ubiquitin-proteasome system in atherosclerosis: status quo, challenges, and perspectives
Antioxidants & Redox Signaling 21 (17): 2344-2363 (2014-11-24)



Lee D.H.; Heidecke H.; Schroeder A.; Paul F.; Wachter R.; Hoffmann R.; Ellrichmann G.; Dragun D.; Waschbisch A.; Stegbauer J.; Klotz P.; Gold R.; Dechend R.; Mueller D.N.; Saft C.; Linker R.A.
Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease
Molecular Neurodegeneration 9 (1): 49 (2014-11-15)



Schmieder R.E.; Schmidt S.T.; Riemer T.; Dechend R.; Hagedorn I.; Senges J.; Messerli F.H.; Zeymer U.
Disproportional decrease in office blood pressure compared with 24-hour ambulatory blood pressure with antihypertensive treatment: dependency on pretreatment blood pressure levels
Hypertension 64 (5): 1067-1072 (2014-11)



Marko L.; Henke N.; Park J.K.; Spallek B.; Qadri F.; Balogh A.; Apel I.J.; Oravecz-Wilson K.I.; Choi M.; Przybyl L.; Binger K.J.; Haase N.; Wilck N.; Heuser A.; Fokuhl V.; Ruland J.; Lucas P.C.; McAllister-Lucas L.M.; Luft F.C.; Dechend R.; Mueller D.N.
Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling
Hypertension 64 (5): 1032-1039 (2014-11)



Zeymer U.; Dechend R.; Riemer T.; Kaiser E.; Senges J.; Pittrow D.; Schmieder R.E.
1-Year outcomes of hypertension management in 13,000 outpatients under practice conditions: Prospective 3A registry
International Journal of Cardiology 176 (3): 589-594 (2014-10-20)



Dechend R.
Preeclampsia, the heart and the blood pressure [Praeeklampsie, das Herz und der Blutdruck]
Diabetes, Stoffwechsel und Herz 23 (5): 292-293 (2014-10-01)



Derer W.; Dechend R.
Besondere Bluthochdruckfaelle: Leitlinienempfehlungen der European Society of Cardiology und European Society of Hypertension [Special cases of high blood pressure: Guideline recommendations of the European Society of Cardiology and European Society of Hypertension]
Kardiologe 8 (5): 419-428 (2014-10)



Weedon-Fekjaer M.S.; Sheng Y.; Sugulle M.; Johnsen G.M.; Herse F.; Redman C.W.; Lyle R.; Dechend R.; Staff A.C.
Placental miR-1301 is dysregulated in early-onset preeclampsia and inversely correlated with maternal circulating leptin
Placenta 35 (9): 709-717 (2014-09)



Manzel A.; Domenig O.; Ambrosius B.; Kovacs A.; Stegbauer J.; Poglitsch M.; Mueller D.N.; Gold R.; Linker R.A.
Angiotensin IV is induced in experimental autoimmune encephalomyelitis but fails to influence the disease
Journal of Neuroimmune Pharmacology 9 (4): 533-543 (2014-09)



Pulgar V.M.; Yamaleyeva L.M.; Varagic J.; McGee C.M.; Bader M.; Dechend R.; Howlett A.C.; Brosnihan K.B.
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis
Hypertension 64 (3): 619-625 (2014-09)



Amaral L.M.; Kipprono L.; Cornelius D.C.; Shoemaker C.; Wallace K.; Moseley J.; Wallukat G.; Martin J.N.; Dechend R.; Lamarca B.
Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy
American Journal of Obstetrics and Gynecology 211 (2): 158.e1-158.e6 (2014-08)



Balogh A.; Nemeth M.; Koloszar I.; Marko L.; Przybyl L.; Jinno K.; Szigeti C.; Heffer M.; Gebhardt M.; Szeberenyi J.; Mueller D.N.; Setalo G.; Pap M.
Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types
Apoptosis 19 (7): 1080-1098 (2014-07-01)



Balogh A.; Bator J.; Marko L.; Nemeth M.; Pap M.; Setalo G.; Mueller D.N.; Csatary L.K.; Szeberenyi J.
Gene expression profiling in PC12 cells infected with an oncolytic Newcastle disease virus strain
Virus Research 185: 10-22 (2014-06-24)



Derer W.; Dechend R.
Are ACE inhibitors better than angiotensin receptor blockers for diabetics? Surprising results from a large-scale meta-analysis [Sind ACE-Hemmer besser als Angiotensin-Rezeptor-Blocker fuer Diabetiker? Ueberraschende Ergebnisse aus einer großen Metaanalyse]
Diabetes, Stoffwechsel und Herz 23 (3): 174-175 (2014-06-20)



von Versen-Hoeynck F.; Brodowski L.; Dechend R.; Myerski A.C.; Hubel C.A.
Vitamin D antagonizes negative effects of preeclampsia on fetal endothelial colony forming cell number and function
PLoS ONE 9 (6): e98990 (2014-06-03)



Fischer R.; Konkel A.; Mehling H.; Blossey K.; Gapelyuk A.; Wessel N.; von Schacky C.; Dechend R.; Muller D.N.; Rothe M.; Luft F.C.; Weylandt K.; Schunck W.H.
Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway
Journal of Lipid Research 55 (6): 1150-1164 (2014-06)



Jantsch J.; Binger K.J.; Mueller D.N.; Titze J.
Macrophages in homeostatic immune function
Frontiers in Physiology 5: 146 (2014-05)



Titze J.; Mueller D.N.; Luft F.C.
Taking another "look" at sodium
Canadian Journal of Cardiology 30 (5): 473-475 (2014-05)



Haase N.; Rugor J.; Przybyl L.; Qadri F.; Mueller D.N.; Dechend R.
Relaxin does not improve angiotensin II-induced target-organ damage
PLoS ONE 9 (4): e93743 (2014-04-07)



Luft F.C.; Safak E.; Dechend R.
Gunfight at O.K. CORAL
Journal of the American Society of Hypertension 8 (4): 276-280 (2014-04)



Kvehaugen A.S.; Melien O.; Holmen O.L.; Laivuori H.; Dechend R.; Staff A.C.
Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study
BMC Medical Genetics 15: 28 (2014-03-05)



Rakova N.; Muller D.N.; Staff A.C.; Luft F.C.; Dechend R.
Novel ideas about salt, blood pressure, and pregnancy
Journal of Reproductive Immunology 101-102: 135-139 (2014-03)



Derer W.; Dechend R.; Baberg H.
Behandlung der arteriellen Hypertonie - Aspekte der neuen europaeischen Leitlinien [Treatment of arterial hypertension - Issues of the new european guidelines]
Klinikarzt 43 (3): 130-135 (2014-03)



Staff A.C.; Johnsen G.M.; Dechend R.; Redman C.W.G.
Preeclampsia and uteroplacental acute atherosis: immune and inflammatory factors
Journal of Reproductive Immunology 101-102: 120-126 (2014-02)



Manzel A.; Muller D.N.; Hafler D.A.; Erdman S.E.; Linker R.A.; Kleinewietfeld M.
Role of "western diet" in inflammatory autoimmune diseases
Current Allergy and Asthma Reports 14 (1): 404 (2014-01)



2013

Linker R.A.; Magnus T.; Korn T.; Kleinschnitz C.; Meuth S.G.
Report on the 5'th scientific meeting of the "Verein zur Foerderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013
Experimental and Translational Stroke Medicine 5 (1): 15 (2013-12-11)



Cornelius D.C.; Hogg J.P.; Scott J.; Wallace K.; Herse F.; Moseley J.; Wallukat G.; Dechend R.; Lamarca B.
Administration of interleukin-17 soluble receptor C suppresses TH17 cells, oxidative stress, and hypertension in response to placental ischemia during pregnancy
Hypertension 62 (6): 1068-1073 (2013-12)



Feldman D.L.; Jin L.; Xuan H.; Persohn E.; Zhou W.; Schuetz H.; Park J.K.; Mueller D.N.; Luft F.C.
The direct renin inhibitor aliskiren localizes and persists in rat kidneys
American Journal of Physiology Renal Physiology 305 (11): F1593-F1602 (2013-12)



Haase N.; Herse F.; Spallek B.; Haase H.; Morano I.; Qadri F.; Szijarto I.A.; Rohm I.; Yilmaz A.; Warrington J.P.; Ryan M.J.; Gollasch M.; Mueller D.N.; Dechend R.; Wallukat G.
Amyloid-{beta} peptides activate {alpha}1-adrenergic cardiovascular receptors
Hypertension 62 (5): 966-972 (2013-11)



Brewer J.; Liu R.; Lu Y.; Scott J.; Wallace K.; Wallukat G.; Moseley J.; Herse F.; Dechend R.; Martin J.N.; Lamarca B.
Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancy
Hypertension 62 (5): 886-892 (2013-11)



Binger K.J.; Muller D.N.
Autophagy and the (pro)renin receptor
Frontiers in Endocrinology 4: 155 (2013-10-21)



Lehmann M.V.; Zeymer U.; Dechend R.; Kaiser E.; Hagedorn I.; Deeg E.; Senges J.; Schmieder R.E.
Ambulatory blood pressure monitoring: Is it mandatory for blood pressure control in treated hypertensive patients? Prospective observational study
International Journal of Cardiology 168 (3): 2255-2263 (2013-10-03)



Giral M.; Foucher Y.; Dufay A.; Van Huyen J.P.D.; Renaudin K.; Moreau A.; Philippe A.; Hegner B.; Dechend R.; Heidecke H.; Brouard S.; Cesbron A.; Castagnet S.; Devys A.; Soulillou J.P.; Dragun D.
Pretransplant sensitization against angiotensin II type 1 receptor is a risk factor for acute rejection and graft loss
American Journal of Transplantation 13 (10): 2567-2576 (2013-10)



Goldman-Wohl D.; Cesla T.; Smith Y.; Greenfield C.; Dechend R.; Staff A.C.; Sugulle M.; Weedon-Fekjaer M.S.; Johnsen G.M.; Yagel S.; Haimov-Kochman R.
Expression profiling of autophagy associated genes in placentas of preeclampsia
Placenta 34 (10): 959-962 (2013-10)



Westphal C.; Spallek B.; Konkel A.; Marko L.; Qadri F.; Degraff L.M.; Schubert C.; Bradbury J.A.; Regitz-Zagrosek V.; Falck J.R.; Zeldin D.C.; Mueller D.N.; Schunck W.H.; Fischer R.
CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophy
PLoS ONE 8 (8): e73490 (2013-08-30)



Savoia C.; Arrabito E.; Parente R.; Sada L.; Madaro L.; Nicoletti C.; Zezza L.; Alonzo A.; Rubattu S.; Michelini S.; Muller D.N.; Volpe M.
The direct renin inhibitor aliskiren improves vascular remodelling in transgenic rats harbouring human renin and angiotensinogen genes
Clinical Science 125 (4): 183-189 (2013-08-01)



Freitag N.; Tirado-Gonzalez I.; Barrientos G.; Herse F.; Thijssen V.L.J.L.; Weedon-Fekjaer S.M.; Schulz H.; Wallukat G.; Klapp B.F.; Nevers T.; Sharma S.; Staff A.C.; Dechend R.; Blois S.M.
Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia
Proceedings of the National Academy of Sciences of the United States of America 110 (28): 11451-11456 (2013-07-09)



Wiig H; Schroeder A; Neuhofer W; Jantsch J; Kopp C; Karlsen T.V.; Boschmann M; Goss J; Bry M; Rakova N; Dahlmann A; Brenner S; Tenstad O; Nurmi H; Mervaala E; Wagner H; Beck FX; Mueller D.N.; Kerjaschki D; Luft F.C.; Harrison D.G.; Alitalo K; Titze J
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure
Journal of Clinical Investigation 123 (7): 2803-2815 (2013-07-01)



Dechend R.
Aktuelle Aspekte der Herzinsuffizienz [Current aspects of heart failure]
Diabetes, Stoffwechsel und Herz 22 (3): 182-183 (2013-06-20)



Novotny S.; Wallace K.; Herse F.; Moseley J.; Darby M.; Heath J.; Gill J.; Wallukat G.; Martin J.N.; Dechend R.; LaMarca B.
CD4(+) T cells play a critical role in mediating hypertension in response to placental ischemia
Journal of Hypertension : Open Access 2: 116 (2013-06-17)



Lueders S.; Dechend R.; Eckert S.; Mengden T.; Nuernberger J.; Tholl U.; Sanner B.
24-h-Langzeitblutdruckmessung (ABDM): Statement der Deutschen Hochdruckliga e. V. DHL (Deutsche Gesellschaft fuer Hypertonie und Praevention), Sektion Hochdruckdiagnostik [Ambulatory blood pressure monitoring (ABPM): Statement of the German Hypertension League DHL (German Society of Hypertension and Prevention), working group for hypertension diagnostics]
Kardiologe 7 (3): 194-208 (2013-06)



Kusch A.; Hoff U.; Bubalo G.; Zhu Y.; Fechner M.; Schmidt-Ullrich R.; Marko L.; Mueller D.N.; Schmidt-Ott K.M.; Guergen D.; Blum M.; Schunck W.H.; Dragun D.
Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury
Acta Physiologica 208 (1): 25-40 (2013-05)



Wallace K.; Martin J.N.; Tam K.T.; Wallukat G.; Dechend R.; Lamarca B.; Owens M.Y.
Seeking the mechanism(s) of action for corticosteroids in HELLP syndrome: SMASH study
American Journal of Obstetrics and Gynecology 208 (5): 380.e1-380.e8 (2013-05)



Kleinewietfeld M.; Manzel A.; Titze J.; Kvakan H.; Yosef N.; Linker R.A.; Muller D.N.; Hafler D.A.
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
Nature 496 (7446): 518-522 (2013-04-25)



Dechend R.
Clarifying the molecular biology of preeclampsia
Circulation 127 (14): F79-F81 (2013-04)



Herse F.; Lamarca B.
Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertension
American Journal of Reproductive Immunology 69 (4): 413-418 (2013-04)



Singer E.; Marko L.; Paragas N.; Barasch J.; Dragun D.; Mueller D.N.; Budde K.; Schmidt-Ott K.M.
Neutrophil gelatinase-associated lipocalin: pathophysiology and clinical applications
Acta Physiologica 207 (4): 663-672 (2013-04)



Kierdorf K.; Erny D.; Goldmann T.; Sander V.; Schulz C.; Perdiguero E.G.; Wieghofer P.; Heinrich A.; Riemke P.; Hoelscher C.; Mueller D.N.; Luckow B.; Brocker T.; Debowski K.; Fritz G.; Opdenakker G.; Diefenbach A.; Biber K.; Heikenwalder M.; Geissmann F.; Rosenbauer F.; Prinz M.
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Nature Neuroscience 16 (3): 273-280 (2013-03)



Kvehaugen A.S.; Melien O.; Holmen O.L.; Laivuori H.; Oian P.; Andersgaard A.B.; Dechend R.; Staff A.C.
Single nucleotide polymorphisms in G protein signaling pathway genes in preeclampsia
Hypertension 61 (3): 655-661 (2013-03)



Staff A.C.; Dechend R.; Redman C.W.G.
Preeclampsia, acute atherosis of the spiral arteries and future cardiovascular disease: Two new hypotheses
Placenta 34 (Suppl.): S73-S78 (2013-03)



Kopp C.; Linz P.; Dahlmann A.; Hammon M.; Jantsch J.; Mueller D.N.; Schmieder R.E.; Cavallaro A.; Eckardt K.U.; Uder M.; Luft F.C.; Titze J.
23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients
Hypertension 61 (3): 635-640 (2013-03)



Dechend R.
The significance of heart rate for hypertension [Die Bedeutung der Herzfrequenz fuer die Hypertonie]
Diabetes, Stoffwechsel und Herz 22 (1): 50-51 (2013-02-20)



Rakova N.; Juettner K.; Dahlmann A.; Schroeder A.; Linz P.; Kopp C.; Rauh M.; Goller U.; Beck L.; Agureev A.; Vassilieva G.; Lenkova L.; Johannes B.; Wabel P.; Moissl U.; Vienken J.; Gerzer R.; Eckardt K.U.; Mueller D.N.; Kirsch K.; Morukov B.; Luft F.C.; Titze J.
Long-term space flight simulation reveals infradian rhythmicity in human na(+) balance
Cell Metabolism 17 (1): 125-131 (2013-01-08)



Safak E.; Wilke C.; Derer W.; Busjahn A.; Gross M.; Moeckel M.; Mueller D.N.; Luft F.C.; Dechend R.
Long-term follow-up of patients with atherosclerotic renal artery disease
Journal of the American Society of Hypertension 7 (1): 24-31 (2013-01)



2012

Herse F.; LaMarca B.; Hubel C.A.; Kaartokallio T.; Lokki A.I.; Ekholm E.; Laivuori H.; Gauster M.; Huppertz B.; Sugulle M.; Ryan M.J.; Novotny S.; Brewer J.; Park J.K.; Kacik M.; Hoyer J.; Verlohren S.; Wallukat G.; Rothe M.; Luft F.C.; Muller D.N.; Schunck W.H.; Staff A.C.; Dechend R.
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia
Circulation 126 (25): 2990-2999 (2012-12-18)



Marko L.; Kvakan H.; Park J.K.; Qadri F.; Spallek B.; Binger K.J.; Bowman E.P.; Kleinewietfeld M.; Fokuhl V.; Dechend R.; Mueller D.N.
Interferon-gamma signaling inhibition ameliorates angiotensin II-induced cardiac damage
Hypertension 60 (6): 1430-1436 (2012-12)



Sugulle M.; Herse F.; Seiler M.; Dechend R.; Staff A.C.
Cardiovascular risk markers in pregnancies complicated by diabetes mellitus or preeclampsia
Pregnancy Hypertension 2 (4): 403-410 (2012-10)



Dechend R.
Hypertonie und Depression : Zusammenhaenge und Probleme des gemeinsamen ­Auftretens [Hypertension and depression : context and issues of joint appearances]
Diabetes, Stoffwechsel und Herz 21 (5): 334-335 (2012-10)



Dhillion P.; Wallace K.; Herse F.; Scott J.; Wallukat G.; Heath J.; Mosely J.; Martin J.N.; Dechend R.; LaMarca B.
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy
American Journal of Physiology Regulatory Integrative and Comparative Physiology 303 (4): R353-R358 (2012-08-15)



Koehn C.; Schleifenbaum J.; Szijarto I.A.; Marko L.; Dubrovska G.; Huang Y.; Gollasch M.
Differential effects of cystathionine-gamma-lyase-dependent vasodilatory H(2)S in periadventitial vasoregulation of rat and mouse aortas
PLoS ONE 7 (8): e41951 (2012-08-03)



Dechend R.; Kaiser E.; Derer W.; Deeg E.; Busjahn A.; Schmieder R.E.; Zeymer U.
Guideline adherence in cardiovascular risk assessment and analysis in 15,000 hypertensive German patients in real life: results of the Prospective 3A Registry
Journal of Clinical Hypertension 14 (8): 496-501 (2012-08)



Mueller D.N.; Binger K.J.; Riediger F.
Prorenin receptor regulates more than the renin-angiotensin system
Annals of Medicine 44 (Suppl 1): S43-S48 (2012-06)



Luft F.C.; Dechend R.; Mueller D.N.
Immune mechanisms in angiotensin II-induced target-organ damage
Annals of Medicine 44 (Suppl 1): S49-S54 (2012-06)



Novotny S.R.; Wallace K.; Heath J.; Moseley J.; Dhillon P.; Weimer A.; Wallukat G.; Herse F.; Wenzel K.; Martin J.N.; Dechend R.; Lamarca B.
Activating autoantibodies to the angiotensin receptor are important in mediating hypertension in response to adoptive transfer of RUPP CD4+ T lymphocytes
American Journal of Physiology Regulatory Integrative and Comparative Physiology 302 (10): R1197-R1201 (2012-05-15)



Volpe M.; Danser A.H.; Menard J.; Waeber B.; Mueller D.N.; Maggioni A.P.; Ruilope L.M.
Inhibition of the renin-angiotensin-aldosterone system: is there room for dual blockade in the cardiorenal continuum?
Journal of Hypertension 30 (4): 647-654 (2012-04)



Jensen F.; Wallukat G.; Herse F.; Budner O.; El-Mousleh T.; Costa S.D.; Dechend R.; Zenclussen A.C.
CD19+CD5+ cells as indicators of preeclampsia
Hypertension 59 (4): 861-868 (2012-04)



Derer W.; Mueller D.N.; Dechend R.
Neue Antihypertensiva in Sicht [New antihypertensive drugs]
MMW Fortschritte der Medizin 154 (4): 72-73 (2012-03-08)



Zeymer U.; Dechend R.; Deeg E.; Kaiser E.; Senges J.; Pittrow D.; Schmieder R.
Aliskiren for the treatment of essential hypertension under real-life practice conditions: design and baseline data of the prospective 3A registry
International Journal of Clinical Practice 66 (3): 251-261 (2012-03)



Acharya G.; Albrecht C.; Benton S.J.; Cotechini T.; Dechend R.; Dilworth M.R.; Duttaroy A.K.; Grotmol T.; Heazell A.E.; Jansson T.; Johnstone E.D.; Jones H.N.; Jones R.L.; Lager S.; Laine K.; Nagirnaja L.; Nystad M.; Powell T.; Redman C.; Sadovsky Y.; Sibley C.; Troisi R.; Wadsack C.; Westwood M.; Lash G.E.
IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems - a translational approach
Placenta 33 (Suppl): S4-S8 (2012-02)



Sugulle M.; Herse F.; Hering L.; Mockel M.; Dechend R.; Staff A.C.
Cardiovascular biomarker midregional proatrial natriuretic peptide during and after preeclamptic pregnancies
Hypertension 59 (2): 395-401 (2012-02)



Dechend R.; Staff A.C.
Placenta messages to the mother: not just debris
Hypertension 59 (2): 191-193 (2012-02)



Finckenberg P.; Eriksson O.; Baumann M.; Merasto S.; Lalowski M.M.; Levijoki J.; Haasio K.; Kytoe V.; Mueller D.N.; Luft F.C.; Oresic M.; Mervaala E.
Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy
Hypertension 59 (1): 76-84 (2012)



Kopp C.; Linz P.; Wachsmuth L.; Dahlmann A.; Horbach T.; Schoefl C.; Renz W.; Santoro D.; Niendorf T.; Mueller D.N.; Neininger M.; Cavallaro A.; Eckardt K.U.; Schmieder R.E.; Luft F.C.; Uder M.; Titze J.
23Na magnetic resonance imaging of tissue sodium
Hypertension 59 (1): 167-172 (2012-01)



Verlohren S.; Stepan H.; Dechend R.
Angiogenic growth factors in the diagnosis and prediction of pre-eclampsia
Clinical Science 122 (2): 43-52 (2012-01-01)



Dechend R.; Dragun D.; Herse F.; Riemekasten G.; Schulze-Forster K.; Mueller D.N.; Heidecke H.
Activating autoantibodies against the AT1-receptor in vascular disease
Transplantationsmedizin 24 (1): 20-26 (2012)



Jung F.; Schulz C.; Blaschke F.; Muller D.N.; Mrowietz C.; Franke R.P.; Lendlein A.; Schunck W.H.
Effect of cytochrome P450-dependent epoxyeicosanoids on Ristocetin-induced thrombocyte aggregation
Clinical Hemorheology and Microcirculation 52 (2-4): 403-416 (2012)



2011

Searle J.; Mockel M.; Gwosc S.; Datwyler S.A.; Qadri F.; Albert G.I.; Holert F.; Isbruch A.; Klug L.; Mueller D.N.; Dechend R.; Muller R.; Vollert J.O.; Slagman A.; Mueller C.; Herse F.
Heparin strongly induces soluble fms-like tyrosine kinase 1 release in vivo and in vitro
Arteriosclerosis Thrombosis and Vascular Biology 31 (12): 2972-2974 (2011-12)



da Costa Goncalves A.C.; Fontes M.A.; Klussmann E.; Qadri F.; Janke J.; Gollasch M.; Schleifenbaum J.; Mueller D.; Jordan J.; Tank J.; Luft F.C.; Gross V.
Spinophilin regulates central angiotensin II-mediated effect on blood pressure
Journal of Molecular Medicine 89 (12): 1219-1229 (2011-12)



Riediger F.; Quack I.; Qadri F.; Hartleben B.; Park J.K.; Potthoff S.A.; Sohn D.; Sihn G.; Rousselle A.; Fokuhl V.; Maschke U.; Purfuerst B.; Schneider W.; Rump L.C.; Luft F.C.; Dechend R.; Bader M.; Huber T.B.; Nguyen G.; Mueller D.N.
Prorenin receptor is essential for podocyte autophagy and survival
Journal of the American Society of Nephrology 22 (12): 2193-2202 (2011-12)



Batenburg W.W.; Lu X.; Leijten F.; Maschke U.; Mueller D.N.; Danser A.H.J.
Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur?
Hypertension 58 (6): 1111-1119 (2011-12)



Park J.B.; Kim B.K.; Kwon Y.W.; Muller D.N.; Lee H.C.; Youn S.W.; Choi Y.E.; Lee S.W.; Yang H.M.; Cho H.J.; Park K.W.; Kim H.S.
Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with Paclitaxel infusion
PLoS ONE 6 (11): e28327 (2011-11-29)



Derer W.; Mueller D.N.; Dechend R.
Stellenwert der fixen Dreierkombination [The role of triple-drug, fixed-dose combinations for the treatment of hypertension]
MMW: Fortschritte der Medizin 153 (46): 50-51 (2011-11-17)



Lamarca B.; Speed J.; Ray L.F.; Cockrell K.; Wallukat G.; Dechend R.; Granger J.
Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activation
International Journal of Interferon, Cytokine and Mediator Research 2011 (3): 65-70 (2011-11-03)



Mengden T.; Dechend R.; Lueders S.; Eckert S.; Tholl U.; Sanner B.
Praxisleitlinien fuer Heimblutdruckmessung [Practice guidelines for home blood pressure measurement]
Deutsche Medizinische Wochenschrift 136 (46): 2374-2377 (2011-11)



Balogh A.; Pap M.; Marko L.; Koloszar I.; Csatary L.K.; Szeberenyi J.
A simple fluorescent labeling technique to study virus adsorption in Newcastle disease virus infected cells
Enzyme and Microbial Technology 49 (3): 255-259 (2011-08-10)



Wenzel K.; Rajakumar A.; Haase H.; Geusens N.; Hubner N.; Schulz H.; Brewer J.; Roberts L.; Hubel C.A.; Herse F.; Hering L.; Qadri F.; Lindschau C.; Wallukat G.; Pijnenborg R.; Heidecke H.; Riemekasten G.; Luft F.C.; Muller D.N.; Lamarca B.; Dechend R.
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats
Hypertension 58 (1): 77-84 (2011-07)



Kvehaugen A.S.; Dechend R.; Ramstad H.B.; Troisi R.; Fugelseth D.; Staff A.C.
Endothelial function and circulating biomarkers are disturbed in women and children after preeclampsia
Hypertension 58 (1): 63-69 (2011-07)



Herse F.; Fain J.N.; Janke J.; Engeli S.; Kuhn C.; Frey N.; Weich H.A.; Bergmann A.; Kappert K.; Karumanchi S.A.; Luft F.C.; Mueller D.N.; Staff A.C.; Dechend R.
Adipose tissue-derived soluble fms-like tyrosine kinase 1 is an obesity-relevant endogenous paracrine adipokine
Hypertension 58 (1): 37-42 (2011-07)



Parrish M.R.; Wallace K.; Tam Tam K.B.; Herse F.; Weimer A.; Wenzel K.; Wallukat G.; Ray L.F.; Arany M.; Cockrell K.; Martin J.N.; Dechend R.; Lamarca B.
Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertension
American Journal of Hypertension 24 (7): 835-840 (2011-07)



Falck J.R.; Wallukat G.; Puli N.; Goli M.; Arnold C.; Konkel A.; Rothe M.; Fischer R.; Mueller D.N.; Schunck W.H.
17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues
Journal of Medicinal Chemistry 54 (12): 4109-4118 (2011-06-23)



Parrish M.R.; Ryan M.J.; Glover P.; Brewer J.; Ray L.; Dechend R.; Martin J.N.; Lamarca B.B.
Angiotensin II type 1 autoantibody induced hypertension during pregnancy is associated with renal endothelial dysfunction
Gender Medicine 8 (3): 184-188 (2011-06)



Mueller D.N.; Kleinewietfeld M.; Kvakan H.
Vitamin D review
Journal of the Renin Angiotensin Aldosterone System 12 (2): 125-128 (2011-06)



Lamarca B.; Wallace K.; Herse F.; Wallukat G.; Martin J.N.; Weimer A.; Dechend R.
Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes
Hypertension 57 (4): 865-871 (2011-04)



Mueller D.N.; Kvakan H.; Luft F.C.
Immune-related effects in hypertension and target-organ damage
Current Opinion in Nephrology and Hypertension 20 (2): 113-117 (2011-03)



Riemekasten G.; Philippe A.; Naether M.; Slowinski T.; Mueller D.N.; Heidecke H.; Matucci-Cerinic M.; Czirjak L.; Lukitsch I.; Becker M.; Kill A.; van Laar J.M.; Catar R.; Luft F.C.; Burmester G.R.; Hegner B.; Dragun D.
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis
Annals of the Rheumatic Diseases 70 (3): 530-536 (2011-03)



2010

Staff A.C.; Dechend R.; Pijnenborg R.
Learning from the placenta: acute atherosis and vascular remodeling in preeclampsia-novel aspects for atherosclerosis and future cardiovascular health
Hypertension 56 (6): 1026-1034 (2010-12)



Schmerbach K.; Pfab T.; Zhao Y.; Culman J.; Mueller S.; Villringer A.; Mueller D.N.; Hocher B.; Unger T.; Thoene-Reineke C.
Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes
PLoS ONE 5 (11): e15052 (2010-11-29)



Arnold C.; Markovic M.; Blossey K.; Wallukat G.; Fischer R.; Dechend R.; Konkel A.; von Schacky C.; Luft F.C.; Mueller D.N.; Rothe M.; Schunck W.H.
Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of omega-3 fatty acids
Journal of Biological Chemistry 285 (43): 32720-32733 (2010-10-22)



Biala A.; Martonen E.; Kaheinen P.; Levijoki J.; Finckenberg P.; Merasto S.; Louhelainen M.; Mueller D.N.; Luft F.C.; Mervaala E.
Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure
Hypertension Research 33 (10): 1004-1011 (2010-10)



Verlohren S.; Geusens N.; Morton J.; Verhaegen I.; Hering L.; Herse F.; Dudenhausen J.W.; Mueller D.N.; Luft F.C.; Cartwright J.E.; Davidge S.T.; Pijnenborg R.; Dechend R.
Inhibition of trophoblast-induced spiral artery remodeling reduces placental perfusion in rat pregnancy
Hypertension 56 (2): 304-310 (2010-08)



Parrish M.R.; Murphy S.R.; Rutland S.; Wallace K.; Wenzel K.; Wallukat G.; Keiser S.; Ray L.F.; Dechend R.; Martin J.N.; Granger J.P.; Lamarca B.
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy
American Journal of Hypertension 23 (8): 911-916 (2010-08)



Hering L.; Herse F.; Geusens N.; Verlohren S.; Wenzel K.; Staff A.C.; Brosnihan K.B.; Huppertz B.; Luft F.C.; Mueller D.N.; Pijnenborg R.; Cartwright J.E.; Dechend R.
Effects of circulating and local uteroplacental angiotensin II in rat pregnancy
Hypertension 56 (2): 311-318 (2010-08)



Titze J.; Mueller D.N.; Luft F.C.
Response to Blood pressure control: a facelift for macrophages?
Hypertension 56 (2): E24 (2010-08)



Taylor J.; Mueller D.N.
Spotlight: Dominik N. Mueller, PhD
Circulation 121 (24): F139-F141 (2010-06-22)



Biala A.; Tauriainen E.; Siltanen A.; Shi J.; Merasto S.; Louhelainen M.; Martonen E.; Finckenberg P.; Mueller D.N.; Mervaala E.
Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes
Blood Pressure 19 (3): 196-205 (2010-06)



Maschke U.; Mueller D.N.
The (pro)renin receptor and the mystic HRP -Is there a role in cardiovascular disease?
Frontiers in Bioscience 2: 1250-1253 (2010-06-01)



Geusens N.; Hering L.; Verlohren S.; Luyten C.; Drijkoningen K.; Taube M.; Vercruysse L.; Hanssens M.; Dechend R.; Pijnenborg R.
Changes in endovascular trophoblast invasion and spiral artery remodelling at term in a transgenic preeclamptic rat model
Placenta 31 (4): 320-326 (2010-04)



Machnik A.; Dahlmann A.; Kopp C.; Goss J.; Wagner H.; van Rooijen N.; Eckardt K.U.; Mueller D.N.; Park J.K.; Luft F.C.; Kerjaschki D.; Titze J.
Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats
Hypertension 55 (3): 755-761 (2010-03)



Wenzel K.; Wallukat G.; Qadri F.; Huebner N.; Schulz H.; Hummel O.; Herse F.; Heuser A.; Fischer R.; Heidecke H.; Luft F.C.; Mueller D.N.; Dietz R.; Dechend R.
alpha(1A)-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats
PLoS ONE 5 (2): e9409 (2010-02-24)



Derer W.; Dechend R.; Mueller D.N.
Aldosteronantagonisten: Welchen Stellenwert haben sie in der antihypertensien Therapie? [Mineralocorticoid receptor antagonists: inhibition of the renin angiotensin system]
MMW: Fortschritte der Medizin 152 (6): 48-49 (2010-02-11)



Mervaala E.; Biala A.; Merasto S.; Lempiaeinen J.; Mattila I.; Martonen E.; Eriksson O.; Louhelainen M.; Finckenberg P.; Kaheinen P.; Mueller D.N.; Luft F.C.; Lapatto R.; Oresic M.
Metabolomics in angiotensin II-induced cardiac hypertrophy
Hypertension 55 (2): 508-515 (2010-02)



Brosnihan K.B.; Hering L.; Dechend R.; Chappell M.C.; Herse F.
Increased angiotensin II in the mesometrial triangle of a transgenic rat model of preeclampsia
Hypertension 55 (2): 562-566 (2010-02)



Jauhiainen T.; Pilvi T.; Cheng Z.J.; Kautiainen H.; Mueller D.N.; Vapaatalo H.; Korpela R.; Mervaala E.
Milk products containing bioactive tripeptides have an antihypertensive effect in double transgenic rats (dTGR) harbouring human renin and human angiotensinogen genes
Journal of Nutrition and Metabolism 2010: 287030 (2010)



Nguyen G.; Mueller D.N.
The biology of the (pro)renin receptor
Journal of the American Society of Nephrology 21 (1): 18-23 (2010-01)



2009

Ritz E.; Krum H.; Schlaich M.; Whitbourn R.; Sobotka P.A.; Sadowski J.; Bartus K.; Kapelak B.; Walton A.; Sievert H.; Thambar S.; Abraham W.T.; Esler M.; Wang Y.; Tsun Z.; Machnik A.; Neuhofer W.; Jantsch J.; Dahlmann A.; Tammela T.; Machura K.; Park J.K.; Beck F.X.; Mueller D.N.; Derer W.; Goss J.; Ziomber A.; Dietsch P.; Wagner H.; van Rooijen N.; Kurtz A.; Hilgers K.F.; Alitalo K.; Eckardt K.U.; Luft F.C.; Kerjaschki D.; Titze J.
New approaches to pathogenesis and management of hypertension
Clinical Journal of the American Society of Nephrology 4 (12): 1886-1891 (2009-12)



Dechend R.; Derer W.; Mueller D.N.
Antihypertensive Behandlung. Bei Risikopatienten von Anfang an fix kombinieren [Fixed-dose combinations in antihypertensive treatment: is it necessary to examine the effectiveness of each component?]
MMW: Fortschritte der Medizin 151 (45): 46-47 (2009-11-05)



Lamarca B.; Parrish M.; Ray L.F.; Murphy S.R.; Roberts L.; Glover P.; Wallukat G.; Wenzel K.; Cockrell K.; Martin J.N.; Ryan M.J.; Dechend R.
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats - role of endothelin-1
Hypertension 54 (4): 905-909 (2009-10)



Kvakan H.; Luft F.C.; Mueller D.N.
Role of the immune system in hypertensive target organ damage
Trends in Cardiovascular Medicine 19 (7): 242-246 (2009-10)



Stegbauer J.; Lee D.H.; Seubert S.; Ellrichmann G.; Manzel A.; Kvakan H.; Mueller D.N.; Gaupp S.; Rump L.C.; Gold R.; Linker R.A.
Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system
Proceedings of the National Academy of Sciences of the United States of America 106 (35): 14942-14947 (2009-09-01)



Park J.K.; Theuer S.; Kirsch T.; Lindschau C.; Klinge U.; Heuser A.; Plehm R.; Todiras M.; Carmeliet P.; Haller H.; Luft F.C.; Mueller D.N.; Fiebeler A.
Growth arrest specific protein 6 participates in DOCA-induced target-organ damage
Hypertension 54 (2): 359-364 (2009-08)



Sugulle M.; Dechend R.; Herse F.; Weedon-Fekjaer M.S.; Johnsen G.M.; Brosnihan K.B.; Anton L.; Luft F.C.; Wollert K.C.; Kempf T.; Staff A.C.
Circulating and placental growth-differentiation factor 15 in preeclampsia and in pregnancy complicated by diabetes mellitus
Hypertension 54 (1): 106-112 (2009-07)



Thomas C.P.; Andrews J.I.; Raikwar N.S.; Kelley E.A.; Herse F.; Dechend R.; Golos T.G.; Liu K.Z.
A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia
Journal of Clinical Endocrinology and Metabolism 94 (7): 2524-2530 (2009-07)



Kvakan H.; Kleinewietfeld M.; Qadri F.; Park J.K.; Fischer R.; Schwarz I.; Rahn H.P.; Plehm R.; Wellner M.; Elitok S.; Gratze P.; Dechend R.; Luft F.C.; Mueller D.N.
Regulatory T cells ameliorate angiotensin II-induced cardiac damage
Circulation 119 (22): 2904-2912 (2009-06-09)



Herse F.; Bai Y.; Staff A.C.; Jiang Y.M.; Dechend R.; Zhou R.
Circulating and uteroplacental adipocytokine concentrations in preeclampsia
Reproductive Sciences 16 (6): 584-590 (2009-06)



Machnik A.; Neuhofer W.; Jantsch J.; Dahlmann A.; Tammela T.; Machura K.; Park J.K.; Beck F.X.; Mueller D.N.; Derer W.; Goss J.; Ziomber A.; Dietsch P.; Wagner H.; van Rooijen N.; Kurtz A.; Hilgers K.F.; Alitalo K.; Eckardt K.U.; Luft F.C.; Kerjaschki D.; Titze J.
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism
Nature Medicine 15 (5): 545-552 (2009-05)



Imboden H.; Patil J.; Nussberger J.; Nicoud F.; Hess B.; Ahmed N.; Schaffner T.; Wellner M.; Mueller D.; Inagami T.; Senbonmatsu T.; Pavel J.; Saavedra J.M.
Endogenous angiotensinergic system in neurons of rat and human trigeminal ganglia
Regulatory Peptides 154 (1-3): 23-31 (2009-04-10)



Pels K.; Schwimmbeck P.L.; Rosenthal P.; Loddenkemper C.; Dang-Heine C.; Rauch U.; Martens H.; Schultheiss H.P.; Dechend R.; Deiner C.
Long-term clopidogrel administration following severe coronary injury reduces proliferation and inflammation via inhibition of nuclear factor-{kappa}B and activator protein 1 activation in pigs
European Journal of Clinical Investigation 39 (3): 174-182 (2009-03)



Park J.K.; Mervaala E.M.; Mueller D.N.; Menne J.; Fiebeler A.; Luft F.C.; Haller H.
Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion
Journal of Hypertension 27 (3): 599-605 (2009-03)



Herse F.; Verlohren S.; Wenzel K.; Pape J.; Mueller D.N.; Modrow S.; Wallukat G.; Luft F.C.; Redman C.W.; Dechend R.
Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study
Hypertension 53 (2): 393-398 (2009-02)



Homuth V.; Derer W.; Dechend R.
Hypertonie und Schwangerschaft [Hypertension and pregnancy]
Deutsche Medizinische Wochenschrift 134 (5): 195-200 (2009-01)



Dechend R.; Luft F.C; Lindheimer M.D.
Agonistic autoantibody-mediated disease
Chesley's Hypertensive Disorders in Pregnancy : 287-296 (2009)



2008

Shagdarsuren E.; Mueller D.N.; Weber C.; Zernecke A.
Complement activation in vascular remodeling and organ damage
Drug Discovery Today: Disease Mechanisms 5 (3-4): e299-e306 (2008-12)



Wenzel K.; Haase H.; Wallukat G.; Derer W.; Bartel S.; Homuth V.; Herse F.; Huebner N.; Schulz H.; Janczikowski M.; Lindschau C.; Schroeder C.; Verlohren S.; Morano I.; Mueller D.N.; Luft F.C.; Dietz R.; Dechend R.; Karczewski P.
Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension
PLoS ONE 3 (11): e3742 (2008-11-17)



Mueller D.N.; Luft F.C.
Renin receptor blockade: a better strategy for renal protection than Renin-Angiotensin system inhibition?
Current Hypertension Reports 10 (5): 405-409 (2008-10)



Krebs C.; Weber M.; Steinmetz O.; Meyer-Schwesinger C.; Stahl R.; Danser A.H.; Garrelds I.; van Goor H.; Nguyen G.; Mueller D.N.; Wenzel U.
Effect of (pro)renin receptor inhibition by a decoy peptide on renal damage in the clipped kidney of Goldblatt rats
Kidney International 74 (6): 823-824 (2008-09-02)



Feldman D.L.; Jin L.; Xuan H.; Contrepas A.; Zhou Y.; Webb R.L.; Mueller D.N.; Feldt S.; Cumin F.; Maniara W.; Persohn E.; Schuetz H.; Jan Danser A.H.; Nguyen G.
Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mREN-2)27 rats
Hypertension 52 (1): 130-136 (2008-07)



Herse F.; Staff A.C.; Hering L.; Mueller D.N.; Luft F.C.; Dechend R.
AT1-receptor autoantibodies and uteroplacental RAS in pregnancy and pre-eclampsia
Journal of Molecular Medicine 86 (6): 697-703 (2008-06)



Batenburg W.W.; de Bruin R.J.; van Gool J.M.; Mueller D.N.; Bader M.; Nguyen G.; Danser A.H.
Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells
Arteriosclerosis Thrombosis and Vascular Biology 28 (6): 1151-1157 (2008-06)



Mueller D.N.; Derer W.; Dechend R.
Aliskiren-mode of action and preclinical data
Journal of Molecular Medicine 86 (6): 659-662 (2008-06)



Gratze P.; Dechend R.; Stocker C.; Park J.K.; Feldt S.; Shagdarsuren E.; Wellner M.; Gueler F.; Rong S.; Gross V.; Obst M.; Plehm R.; Alenina N.; Zenclussen A.; Titze J.; Small K.; Yokota Y.; Zenke M.; Luft F.C.; Mueller D.N.
Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension
Circulation 117 (20): 2645-2656 (2008-05-20)



Molnar G.A.; Lindschau C.; Dubrovska G.; Mertens P.R.; Kirsch T.; Quinkler M.; Gollasch M.; Wresche S.; Luft F.C.; Mueller D.N.; Fiebeler A.
Glucocorticoid-related signaling effects in vascular smooth muscle cells
Hypertension 51 (5): 1372-1378 (2008-05)



Feldt S.; Maschke U.; Dechend R.; Luft F.C.; Mueller D.N.
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling
Journal of the American Society of Nephrology 19 (4): 743-748 (2008-04)



Gross C.M.; Posch M.G.; Geier C.; Olthoff H.; Kraemer J.; Dechend R.; Dietz R.; Oezcelik C.
Subacute coronary stent thrombosis in cancer patients
Journal of the American College of Cardiology 51 (12): 1232-1233 (2008-03-25)



Mueller D.N.; Klanke B.; Feldt S.; Cordasic N.; Hartner A.; Schmieder R.E.; Luft F.C.; Hilgers K.F.
(Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in goldblatt rats
Hypertension 51 (3): 676-681 (2008-03)



Feldt S.; Batenburg W.W.; Mazak I.; Maschke U.; Wellner M.; Kvakan H.; Dechend R.; Fiebeler A.; Burckle C.; Contrepas A.; Danser A.H.; Bader M.; Nguyen G.; Luft F.C.; Mueller D.N.
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
Hypertension 51 (3): 682-688 (2008-03)



Verlohren S.; Niehoff M.; Hering L.; Geusens N.; Herse F.; Tintu A.N.; Plagemann A.; Le Noble F.; Pijnenborg R.; Mueller D.N.; Luft F.C.; Dudenhausen J.W.; Gollasch M.; Dechend R.
Uterine vascular function in a transgenic preeclampsia rat model
Hypertension 51 (2): 547-553 (2008-02)



Hering L.; Herse F.; Verlohren S.; Park J.K.; Wellner M.; Qadri F.; Pijnenborg R.; Staff A.C.; Huppertz B.; Mueller D.N.; Luft F.C.; Dechend R.
Trophoblasts reduce the vascular smooth muscle cell proatherogenic response
Hypertension 51 (2): 554-559 (2008-02)



Fischer R.; Dechend R.; Qadri F.; Markovic M.; Feldt S.; Herse F.; Park J.K.; Gapelyuk A.; Schwarz I.; Zacharzowsky U.B.; Plehm R.; Safak E.; Heuser A.; Schirdewan A.; Luft F.C.; Schunck W.H.; Mueller D.N.
Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension
Hypertension 51 (2): 540-546 (2008-02)



Luft F.C.; Dechend R.; Dragun D.; Mueller D.N.; Wallukat G.
Agonistic antibodies directed at cell surface receptors and cardiovascular disease
Journal of the American Society of Hypertension 2 (1): 8-14 (2008-01)



2007

Batenburg W.W.; Krop M.; Garrelds I.M.; de Vries R.; de Bruin R.J.A.; Burckle C.A.; Mueller D.N.; Bader M.; Nguyen G.; Danser A.H.J.
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
Journal of Hypertension 25 (12): 2441-2453 (2007-12)



Derer W.; Mueller D.N.
Die direkte Renin-Inhibition - ein neuer Ansatz in der therapeutischen Blockade des Renin-Angiotensin-Systems [Direct renin inhibition - a new approach in the therapeutic blockade of the renin-angiotensin system]
Nieren- und Hochdruckkrankheiten 36 (11): 549-550 (2007-11)



Wenzel K.; Geier C.; Qadri F.; Huebner N.; Schulz H.; Erdmann B.; Gross V.; Bauer D.; Dechend R.; Dietz R.; Osterziel K.J.; Spuler S.; Oezcelik C.
Dysfunction of dysferlin-deficient hearts
Journal of Molecular Medicine 85 (11): 1203-1214 (2007-11)



Mueller D.N.
Spotlight on renin. Mechanisms of hypertension-induced target organ damage
Journal of the Renin Angiotensin Aldosterone System 8 (3): 148-150 (2007-09)



Henke N.; Schmidt-Ullrich R.; Dechend R.; Park J.K.; Qadri F.; Wellner M.; Obst M.; Gross V.; Dietz R.; Luft F.C.; Scheidereit C.; Mueller D.N.
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage
Circulation Research 101 (3): 268-276 (2007-08-03)



Schmid M.; Sollwedel A.; Thuere C.; Wafula P.O.; Zenclussen M.L.; Mueller D.N.; Gratze P.; Woiciechowsky C.; Volk H.D.; Zenclussen A.C.
Murine pre-eclampsia induced by unspecific activation of the immune system correlates with alterations in the eNOS and AT1 receptor expression in the kidneys and placenta
Placenta 28 (7): 688-700 (2007-08)



Fischer R.; Dechend R.; Gapelyuk A.; Shagdarsuren E.; Gruner K.; Gruner A.; Gratze P.; Qadri F.; Wellner M.; Fiebeler A.; Dietz R.; Luft F.C.; Mueller D.N.; Schirdewan A.
Angiotensin II-induced sudden arrhythmic death and electrical remodeling
American Journal of Physiology Heart and Circulatory Physiology 293 (2): H1242-H1253 (2007-08-01)



Fischer R.; Gapelyuk A.; Wessel N.; Gruner K.; Gruner A.; Mueller D.; Dietz R.; Schirdewan A.
Time course of changes in cardiac magnetic field mapping after myocardial infarction in rats
International Congress Series 1300 (1300): 484-487 (2007-06)



Dechend R.; Shagdarsuren E.; Gratze P.; Fiebeler A.; Pilz B.; Meiners S.; Derer W.; Feldman D.L.; Webb R.; Mueller D.N.
Low-dose renin inhibitor and low-dose AT(1)-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes
Journal of the Renin Angiotensin Aldosterone System 8 (2): 81-84 (2007-06)



Mueller D.N.; Schmidt C.; Barbosa-Sicard E.; Wellner M.; Gross V.; Hercule H.; Markovic M.; Honeck H.; Luft F.C.; Schunck W.H.
Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation
Biochemical Journal 403 (1): 109-118 (2007-04)



Park J.K.; Fischer R.; Dechend R.; Shagdarsuren E.; Gapeljuk A.; Wellner M.; Meiners S.; Gratze P.; Al-Saadi N.; Feldt S.; Fiebeler A.; Madwed J.B.; Schirdewan A.; Haller H.; Luft F.C.; Mueller D.N.
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage
Hypertension 49 (3): 481-489 (2007-03)



Fiebeler A.; Mueller D.N.; Shagdarsuren E.; Luft F.C.
Aldosterone, mineralocorticoid receptors, and vascular inflammation
Current Opinion in Nephrology and Hypertension 16 (2): 134-142 (2007-03)



Herse F.; Dechend R.; Harsem N.K.; Wallukat G.; Janke J.; Qadri F.; Hering L.; Mueller D.N.; Luft F.C.; Staff A.C.
Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia
Hypertension 49 (3): 604-611 (2007-03)



2006

Burckle C.A.; Danser A.H.J.; Mueller D.N.; Garrelds I.M.; Gasc J.M.; Popova E.; Plehm R.; Peters J.; Bader M.; Nguyen G.
Elevated blood pressure and heart rate in human renin receptor transgenic rats
Hypertension 47 (3): 552-556 (2006-03)



Mueller D.N.; Luft F.C.
Direct renin inhibition with aliskiren in hypertension and target organ damage
Clinical Journal of the American Society of Nephrology 1 (2): 221-228 (2006-03)



Dechend R.; Homuth V.; Wallukat G.; Mueller D.N.; Krause M.; Dudenhausen J.; Haller H.; Luft F.C.
Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia
Journal of the Society for Gynecologic Investigation 13: 79-86 (2006-02)



2005

Shagdarsuren E.; Wellner M.; Braesen J.H.; Park J.K.; Fiebeler A.; Henke N.; Dechend R.; Gratze P.; Luft F.C.; Mueller D.N.
Complement activation in angiotensin II-induced organ damage
Circulation Research 97 (7): 716-724 (2005-08-18)



Pilz B.; Shagdarsuren E.; Wellner M.; Fiebeler A.; Dechend R.; Gratze P.; Meiners S.; Feldman D.L.; Webb R.L.; Garrelds I.M.; Danser A.H.J.; Luft F.C.; Mueller D.N.
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
Hypertension 46 (3): 569-576 (2005-08-15)



Wellner M.; Dechend R.; Park J.K.; Shagdasuren E.; Al-Saadi N.; Kirsch T.; Gratze P.; Schneider W.; Meiners S.; Fiebeler A.; Haller H.; Luft F.C.; Mueller D.N.
Cardiac gene expression profile in rats with terminal heart failure and cachexia
Physiological Genomics 20: 256-267 (2005-01-01)



Dragun D.; Mueller D.N.; Braesen J.H.; Fritsche L.; Nieminen-Kelhae M.; Dechend R.; Kintscher U.; Rudolph B.; Hoebeke J.; Eckert D.; Mazak I.; Plehm R.; Schoenemann C.; Unger T.; Budde K.; Neumayer H.H.; Luft F.C.; Wallukat G.
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8)
New England Journal of Medicine 352 (6): 558-569 (2005-01-01)



Dechend R.; Gratze P.; Wallukat G.; Shagdarsuren E.; Plehm R.; Braesen J.H.; Fiebeler A.; Schneider W.; Caluwaerts S.; Vercruysse L.; Pijnenborg R.; Luft F.C.; Mueller D.N.
Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia
Hypertension 45 (4): 742-746 (2005-01-01)



Dechend R.; Mueller D.N.; Wallukat G.; Homuth V.; Krause M.; Dudenhausen J.; Luft F.C.
Activating auto-antibodies against the AT1 receptor in preeclampsia
Autoimmunity Reviews 4 (1): 61-65 (2005-01-01)



Fiebeler A.; Nussberger J.; Shagdarsuren E.; Rong S.; Hilfenhaus G.; Al-Saadi N.; Dechend R.; Wellner M.; Meiners S.; Maser-Gluth C.; Jeng A.Y.; Webb R.L.; Luft F.C.; Mueller D.N.
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage
Circulation 111 (23): 3087-3094 (2005-01-01)



Finckenberg P.; Merasto S.; Louhelainen M.; Lindgren L.; Vapaatalo H.; Mueller D.N.; Luft F.C.; Mervaala E.M.
Magnesium supplementation prevents angiotensin II-induced myocardial damage and CTGF overexpression
Journal of Hypertension 23: 375-380 (2005-01-01)



2004

Dechend R.; Mueller D.N.; Wallukat G.; Homuth V.; Krause M.; Dudenhausen J.; Luft F.C.
AT1 receptor agonistic antibodies, hypertension, and preeclampsia
Seminars in Nephrology 24: 571-579 (2004-12-01)



Gross V.; Obst M.; Kiss E.; Janke J.; Mazak I.; Shagdarsuren E.; Mueller D.N.; Langenickel T.H.; Groene H.J.; Luft F.C.
Cardiac hypertrophy and fibrosis in chronic L-NAME-treated AT2 receptor-deficient mice
Journal of Hypertension 22 (5): 997-1005 (2004-05)



2003

Finckenberg P.; Inkinen K.; Ahonen J.; Merasto S.; Louhelainen M.; Vapaatalo H.; Mueller D.; Ganten D.; Luft F.C.; Mervaala E.
Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways
American Journal of Pathology 163 (1): 355-366 (2003-07)



2002

Park J.K.; Fiebeler A.; Muller D.N.; Mervaala E.M.A.; Dechend R.; Abou-Rebyeh F.; Luft F.C.; Haller H.
Lacidipine inhibits adhesion molecule and oxidase expression independent of blood pressure reduction in angiotensin-induced vascular injury
Hypertension 39: 685-689 (2002-01-01)



2001

Fiebeler A.; Schmidt F.; Mueller D.N.; Park J.K.; Dechend R.; Bieringer M.; Shagdarsuren E.; Breu V.; Haller H.; Luft F.C.
Mineralocorticoid receptor affects AP-1 and nuclear factor-kappa B activation in angiotensin II-induced cardiac injury
Hypertension 37: 787-793 (2001-01-01)



Mervaala E.M.A.; Cheng Z.J.; Tikkanen I.; Lapatto R.; Nurminen K.; Vapaatalo H.; Mueller D.N.; Fiebeler A.; Ganten U.; Ganten D.; Luft F.C.
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes
Hypertension 37 (2): 414-418 (2001-01-01)



Bader M.; Peters J.; Baltatu O.; Mueller D.N.; Luft F.C.; Ganten D.
Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research
Journal of Molecular Medicine 79 (2): 76-102 (2001-01-01)



Mueller D.N.; Heissmeyer V.; Dechend R.; Hampich F.; Park J.K.; Fiebeler A.; Shagdarsuren E.; Theuer J.; Elger M.; Pilz B.; Breu V.; Schroer K.; Ganten D.; Dietz R.; Haller H.; Scheidereit C.; Luft F.C.
Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage
FASEB Journal 15: 1822-1824 (2001-01-01)



Dechend R.; Fiebeler A.; Park J.K.; Muller D.N.; Theuer J.; Mervaala E.; Bieringer M.; Gulba D.; Dietz R.; Luft F.C.; Haller H.
Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
Circulation 104: 576-581 (2001-01-01)



Dechend R.; Fiebler A.; Lindschau C.; Bischoff H.; Mueller D.N.; Park J.K.; Dietz R.; Haller H.; Luft F.C.
Modulating angiotensin II-induced inflammation by HMG Co-A reductase inhibition
American Journal of Hypertension 14: 55S-61S (2001-01-01)



2000

Park J.K.; Mueller D.N.; Mervaala E.M.A.; Dechend R.; Fiebeler A.; Schmidt F.; Bieringer M.; Schaefer O.; Lindschau C.; Schneider W.; Ganten D.; Luft F.C.; Haller H.
Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects
Kidney International 58 (4): 1420-1430 (2000-10-01)



Muller D.N.; Mervaala E.M.A.; Schmidt F.; Park J.K.; Dechend R.; Genersch E.; Breu V.; Loeffler B.M.; Ganten D.; Schneider W.; Haller H.; Luft F.C.
Effect of Bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage
Hypertension 36 (2): 282-290 (2000-08-01)



Mueller D.N.; Mervaala E.M.A.; Dechend R.; Fiebeler A.; Park J.K.; Schmidt F.; Theuer J.; Breu V.; Mackman N.; Luther T.; Schneider W.; Gulba D.; Ganten D.; Haller H.; Luft F.C.
Angiotensin II (AT1) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy
American Journal of Pathology 157: 111-122 (2000-07-01)



Mervaala E.; Mueller D.N.; Schmidt F.; Park J.K.; Gross V.; Bader M.; Breu V.; Ganten D.; Haller H.; Luft F.C.
Blood pressure-independent effects in rats with human renin and angiotensinogen genes
Hypertension 35 (2): 587-594 (2000-02-01)



Mervaala E.; Mueller D.N.; Park J.K.; Dechend R.; Schmidt F.; Fiebeler A.; Bieringer M.; Breu V.; Ganten D.; Haller H.; Luft F.C.
Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes
Hypertension 35 (1): 360-366 (2000-01-01)



1999

Mervaala E.M.A.; Mueller D.N.; Park J.K.; Schmidt F.; Loehn M.; Breu V.; Dragun D.; Ganten D.; Haller H.; Luft F.C.
Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension
Hypertension 33: 389-395 (1999-01-01)



Mueller D.N.; Hilgers K.F.; Mathews S.; Breu V.; Fischli W.; Uhlmann R.; Luft F.C.
Effects of human prorenin in rats transgenic for human angiotensinogen
Hypertension 33: 312-317 (1999-01-01)



Luft F.C.; Mervaala E.; Mueller D.N.; Gross V.; Schmidt F.; Park J.K.; Schmitz C.; Lippoldt A.; Breu V.; Dechend R.; Dragun D.; Schneider W.; Ganten D.; Haller H.
Hypertension-induced end-organ damage - A new transgenic approach to an old problem
Hypertension 33: 212-218 (1999-01-01)



1998

Mueller D.N.; Luft F.C.
The renin-angiotensin system in the vessel wall
Basic Research in Cardiology 93 (Suppl 2): 7-14 (1998-01-01)