Publications



2017

Sarem Z.; Bumke-Vogt C.; Mahmoud A.M.; Assefa B.; Weickert M.O.; Adamidou A.; Baehr V.; Frystyk J.; Moehlig M.; Spranger J.; Lieske S.; Birkenfeld A.L.; Pfeiffer A.F.H.; Arafat A.M.
Glucagon decreases IGF-1 bioactivity in humans, independently of insulin, by modulating its binding proteins
Journal of Clinical Endocrinology and Metabolism 102 (9): 3480-3490 (2017-09-01)



Maurer L.; Schwarz F.; Fischer-Rosinsky A.; Schlueter N.; Brachs S.; Moehlig M.; Pfeiffer A.; Mai K.; Spranger J.; Bobbert T.
Renal function is independently associated with circulating betatrophin
PLoS ONE 12 (3): e0173197 (2017-03-03)



Wollersheim T.; Frank S.; Mueller M.C.; Skrypnikov V.; Carbon N.M.; Pickerodt P.A.; Spies C.; Mai K.; Spranger J.; Weber-Carstens S.
Measuring Energy Expenditure in extracorporeal lung support Patients (MEEP) - protocol, feasibility and pilot trial
Clinical Nutrition : (2017-01-16)



2016

Maurer L.; Brachs S.; Decker A.M.; Brachs M.; Leupelt V.; Jumpertz von Schwartzenberg R.; Ernert A.; Bobbert T.; Krude H.; Spranger J.; Mai K.
Weight loss partially restores glucose-driven betatrophin response in humans
Journal of Clinical Endocrinology and Metabolism 101 (11): 4014-4020 (2016-11)



Kuehnen P.; Handke D.; Waterland R.A.; Hennig B.J.; Silver M.; Fulford A.J.; Dominguez-Salas P.; Moore S.E.; Prentice A.M.; Spranger J.; Hinney A.; Hebebrand J.; Heppner F.L.; Walzer L.; Groetzinger C.; Gromoll J.; Wiegand S.; Grueters A.; Krude H.
Interindividual variation in DNA methylation at a putative POMC metastable epiallele is associated with obesity
Cell Metabolism 24 (3): 502-509 (2016-09-13)



Brachs M.; Wiegand S.; Leupelt V.; Ernert A.; Kintscher U.; Jumpertz von Schwarzenberg R.; Decker A.M.; Bobbert T.; Huebner N.; Chen W.; Krude H.; Spranger J.; Mai K.
ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss
Metabolism 65 (6): 935-943 (2016-06)



Prehn K.; Jumpertz von Schwartzenberg R.; Mai K.; Zeitz U.; Witte A.V.; Hampel D.; Szela A.M.; Fabian S.; Grittner U.; Spranger J.; Floeel A.
Caloric restriction in older adults - differential effects of weight loss and reduced weight on brain structure and function
Cerebral Cortex 27 (3): 1765-1778 (2016-03)



2015

Jumpertz von Schwartzenberg R.; Elbelt U.; Ventz M.; Mai K.; Kienitz T.; Maurer L; Rose T.; Rueckert J.C.; Strasburger C.J.; Spranger J.
Palliative treatment of uncontrollable hypercalcemia due to parathyrotoxicosis: denosumab as rescue therapy
Endocrinology Diabetes and Metabolism Case Reports 2015: 150082 (2015-10-29)



Ebinger M.; Ipsen N.; Leonards C.O.; Empl L.; Hanne L.; Liman T.; Mai K.; Strasburger C.J.; Spranger J.; Endres M.
Circulating insulin-like growth factor binding protein-3 predicts one-year outcome after ischemic stroke
Experimental and Clinical Endocrinology & Diabetes 123 (8): 461-465 (2015-09)



Mueller S.A.; Amoah S.K.B.; Meese S.; Spranger J.; Mockenhaupt F.P.
High prevalence of anaemia among African migrants in Germany persists after exclusion of iron deficiency and erythrocyte polymorphisms
Tropical Medicine & International Health 20 (9): 1180-1189 (2015-09)



Schwarz F.; Karadeniz Z.; Fischer-Rosinsky A.; Willmes D.M.; Spranger J.; Birkenfeld A.L.
Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2
Aging 7 (8): 553-567 (2015-08)



Bobbert T.; Schwarz F.; Fischer-Rosinsky A.; Maurer L.; Moehlig M.; Pfeiffer A.F.H.; Mai K.; Spranger J.
Chemerin and prediction of diabetes mellitus type 2
Clinical Endocrinology 82 (6): 838-843 (2015-06)



Weygandt M.; Mai K.; Dommes E.; Ritter K.; Leupelt V.; Spranger J.; Haynes J.D.
Impulse control in the dorsolateral prefrontal cortex counteracts post-diet weight regain in obesity
NeuroImage 109: 318-327 (2015-04-01)



Drogan D.; Dunn W.B.; Lin W.; Buijsse B.; Schulze M.B.; Langenberg C.; Brown M.; Floegel A.; Dietrich S.; Rolandsson O.; Wedge D.C.; Goodacre R.; Forouhi N.G.; Sharp S.J.; Spranger J.; Wareham N.J.; Boeing H.
Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study
Clinical Chemistry 61 (3): 487-497 (2015-03)



Elbelt U.; Trovato A.; Kloth M.; Gentz E.; Finke R.; Spranger J.; Galas D.; Weber S.; Wolf C.; Koenig K.; Arlt W.; Buettner R.; May P.; Allolio B.; Schneider J.G.
Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma
Journal of Clinical Endocrinology and Metabolism 100 (1): E119-E128 (2015-01)



2014

Schlueter N.; de Sterke A.; Willmes D.M.; Spranger J.; Jordan J.; Birkenfeld A.L.
Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome
Pharmacology & Therapeutics 144 (1): 12-27 (2014-10)



Abholz H.H.; Egidi G.; Mueller U.A.; Spranger J.
Skepticism is unjustified
Deutsches Aerzteblatt International 111 (25): 433 (2014-06-20)



Bidlingmaier M.; Friedrich N.; Emeny R.T.; Spranger J.; Wolthers O.D.; Roswall J.; Koerner A.; Obermayer-Pietsch B.; Huebener C.; Dahlgren J.; Frystyk J.; Pfeiffer A.F.H.; Doering A.; Bielohuby M.; Wallaschofski H.; Arafat A.M.
Reference intervals for insulin-like growth factor-1 (IGF-1) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-1 immunoassay conforming to recent international recommendations
Journal of Clinical Endocrinology and Metabolism 99 (5): 1712-1721 (2014-05)



Langhans C.; Weber-Carstens S.; Schmidt F.; Hamati J.; Kny M.; Zhu X.; Wollersheim T.; Koch S.; Krebs M.; Schulz H.; Lodka D.; Saar K.; Labeit S.; Spies C.; Hubner N.; Spranger J.; Spuler S.; Boschmann M.; Dittmar G.; Butler-Browne G.; Mouly V.; Fielitz J.
Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy
PLoS ONE 9 (3): e92048 (2014-03-20)



Wollersheim T.; Woehlecke J.; Krebs M.; Hamati J.; Lodka D.; Luther-Schroeder A.; Langhans C.; Haas K.; Radtke T.; Kleber C.; Spies C.; Labeit S.; Schuelke M.; Spuler S.; Spranger J.; Weber-Carstens S.; Fielitz J.
Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness
Intensive Care Medicine 40 (4): 528-538 (2014-02-15)



2013

Arafat A.M.; Weickert M.O.; Adamidou A.; Otto B.; Perschel F.H.; Spranger J.; Moehlig M.; Pfeiffer A.F.H.
The impact of insulin-independent, glucagon-induced suppression of total ghrelin on satiety in obesity and type 1 diabetes mellitus
Journal of Clinical Endocrinology and Metabolism 98 (10): 4133-4142 (2013-10)



Ufer F.; Diederich S.; Pedersen E.B.; Spranger J.; Pfeiffer A.F.H.; Baehr V.; Mai K.
Arginine vasopressin-dependent and AVP-independent mechanisms of renal fluid absorption during thirsting despite glucocorticoid-mediated vasopressin suppression
Clinical Endocrinology 78 (3): 431-437 (2013-03)



Weber-Carstens S.; Schneider J.; Wollersheim T.; Assmann A.; Bierbrauer J.; Marg A.; Al Hasani H.; Chadt A.; Wenzel K.; Koch S.; Fielitz J.; Kleber C.; Faust K.; Mai K.; Spies C.D.; Luft F.C.; Boschmann M.; Spranger J.; Spuler S.
Critical illness myopathy and GLUT4 - significance of insulin and muscle contraction
American Journal of Respiratory and Critical Care Medicine 187 (4): 387-396 (2013-02-15)



2012

Benz V.; Bloch M.; Wardat S.; Boehm C.; Maurer L.; Mahmoodzadeh S.; Wiedmer P.; Spranger J.; Foryst-Ludwig A.; Kintscher U.
Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis
PLoS ONE 7 (5): e37794 (2012-05-25)



Hische M.; Larhlimi A.; Schwarz F.; Fischer-Rosinsky A.; Bobbert T.; Assmann A.; Catchpole G.S.; Pfeiffer A.F.H.; Willmitzer L.; Selbig J.; Spranger J.
A distinct metabolic signature predicts development of fasting plasma glucose
Journal of Clinical Bioinformatics 2: 3 (2012-02-02)



Bierbrauer J.; Koch S.; Olbricht C.; Hamati J.; Lodka D.; Schneider J.; Luther-Schroeder A.; Kleber C.; Faust K.; Wiesener S.; Spies C.D.; Spranger J.; Spuler S.; Fielitz J.; Weber-Carstens S.
Early type II fiber atrophy in intensive care unit patients with nonexcitable muscle membrane
Critical Care Medicine 40 (2): 647-650 (2012-02)



2011

Biedasek K.; Andres J.; Mai K.; Adams S.; Spuler S.; Fielitz J.; Spranger J.
Skeletal muscle 11beta-HSD1 controls glucocorticoid-induced proteolysis and expression of E3 ubiquitin ligases atrogin-1 and MuRF-1
PLoS ONE 6 (1): e16674 (2011-01-31)



2010

Drogan D.; Weikert C.; Dierkes J.; Klipstein-Grobusch K.; Buijsse B.; Moehlig M.; Pfeiffer A.F.; Pischon T.; Spranger J.; Boeing H.
Plasma {gamma}-glutamyltransferase, cysteinyl-glycine, and oxidized low-density lipoprotein: a pathway associated with myocardial infarction risk?
Arteriosclerosis Thrombosis and Vascular Biology 30 (10): 2053-2058 (2010-10)



Weber-Carstens S.; Deja M.; Koch S.; Spranger J.; Bubser F.; Wernecke K.D.; Spies C.D.; Spuler S.; Keh D.
Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study
Critical Care 14 (3): R119 (2010-06-18)



2009

Mai K.; Andres J.; Biedasek K.; Weicht J.; Bobbert T.; Sabath M.; Meinus S.; Reinecke F.; Moehlig M.; Weickert M.O.; Clemenz M.; Pfeiffer A.F.; Kintscher U.; Spuler S.; Spranger J.
Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21
Diabetes 58 (7): 1532-1538 (2009-07)



2008

Adams F.; Boschmann M.; Lobsien E.; Kupsch A.; Lipp A.; Franke G.; Leisse M.C.; Janke J.; Gottschalk S.; Spranger J.; Jordan J.
Influences of levodopa on adipose tissue and skeletal muscle metabolism in patients with idiopathic Parkinson's disease
European Journal of Clinical Pharmacology 64 (9): 863-870 (2008-09)



Weikert C.; Westphal S.; Berger K.; Dierkes J.; Moehlig M.; Spranger J.; Rimm E.B.; Willich S.N.; Boeing H.; Pischon T.
Plasma resistin levels and risk of myocardial infarction and ischemic stroke
The Journal of clinical endocrinology and metabolism 93 (7): 2647-2653 (2008-07)



2007

Pischon T.; Moehlig M.; Hoffmann K.; Spranger J.; Weikert C.; Willich S.N.; Pfeiffer A.F.; Boeing H.
Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels
European Journal of Epidemiology 22 (7): 429-438 (2007-07)