Current Students

 

Christ A, Christa A, Kur E, Lioubinski O, Bachmann S, Willnow TE, Hammes A. LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals. Dev. Cell 2012, 22(2): 268-78

 

von Knobelsdorff-Brenkenhoff F, Dieringer MA, Fuchs K, Hezel F, Renz W, Niendorf T, Schulz-Menger J. Physiological stress during cardiovascular magnetic resonance - handgrip exercise induced hemodynamic effects. J. Cardiovasc. Magn. Reson. 2012, 14 Suppl 1: P229

 

Bierbrauer J, Koch S, Olbricht C, Hamati J, Lodka D, Schneider J, Luther-Schröder A, Kleber C, Faust K, Wiesener S, Spies CD, Spranger J, Spuler S, Fielity J, Weber-Carstens S. Early type II fiber atrophy in intensive care unit patients with nonexcitable muscle membrane. Crit. Care Med. 2012, 40(2): 647-50

 

Tattikota SG, Poy MN. Re-dicing the pancreatic beta-cell: do microRNAs define cellular identity? EMBO J. 2011, 30(5): 797-9

 

Dieringer MA, Renz W, Lindel T, Seifert F, Frauenrath T, von Knobelsdorff-Brenkenhoff F, Waiczies H, Hoffmann W, Rieger J, Pfeiffer H, Ittermann B, Schulz-Menger J, Niendorf T. Design and application of a four-channel transmit/receive surface coil for functional cardiac imaging at 7T. J. Magn. Reson. Imaging 2011, 33(3): 736-41

 

Kur E, Christa A, Veth KN, Gajera CR, Andrade-Navarro MA, Zhang J, Willer JR, Gregg RG, Abdelilah-Seyfried S, Bachmann S, Link BA, Hammes A, Willnow TE. Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development. Dev. Dyn. 2011, 240(6): 1567-77

 

Willecke R, Heuberger J, Grossmann K, Michos O, Schmidt-Ott K, Walentin K, Costantini F, Birchmeier W. The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney. Dev. Biol. 2011, 360(2): 310-7

 

Riediger F, Quack I, Qadri F, Hartleben B, Park JK, Potthoff SA, Sohn D, Sihn G, Rousselle A, Fokuhl V, Maschke U, Purfürst B, Schneider W, Rump LC, Luft FC, Dechend R, Bader M, Huber TB, Nguyen G, Muller DN. Prorenin receptor is essential for podocyte autophagy and survival. J. Am Soc. Nephrol. 2011, 22(12): 2193-202

 

Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, Zambrowicz B, Gerrits H, Gossen JA, He X, Bader M, Williams BO, Warman ML, Robling AG. Lrp5 functions in bone to regulate bone mass. Nat. Med. 2011, 17(6): 684-91

 

Werth M, Walentin K, Aue A, Schönheit J, Wuebken A, Pode-Shakked N, Vilianovitch L, Erdmann B, Dekel B, Bader M, Barasch J, Rosenbauer F, Luft FC, Schmidt-Ott KM. The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex. Development 2010, 137(22): 3835-45

 

John T, Lodka D, Kohl B, Ertel W, Jammrath J, Conrad C, Stoll C, Busch C, Schulze-Tanzil G. Effect of pro-inflammatory and immunoregulatory cytokines on human tenocytes. J. Orthop. Res. 2010, 28(8): 1071-7

 

Matthes S, Mosienko V, Bashammakh S, Alenina N, Bader M. Tryptophan hydroxylase as novel target for the treatment of depressive disorders. Pharmacology 2010, 85(2): 95-109

 

Frauenrath T, Hezel F, Renz W, d'Orth Tde G, Dieringer M, von Knobelsdorff-Brenkenhoff F, Prothmann M, Schulz Menger J, Niendorf T. Acoustic cardiac triggering: a practical solution for synchronization and gating of cardiovascular magentic resonance at 7 Tesla. J. Cardiovasc. Magn. Reson. 2010, 12: 67

 

von Knobelsdorff-Brenkenhoff F, Frauenrath T, Prothmann M, Dieringer MA, Hezel F, Renz W, Kretschel K, Niendorf T, Schulz-Menger J. Cardiac chamber quantification using magnetic resonance imaging at 7 Tesla--a pilot study. Eur. Radiol. 2010, 20(12): 2844-52

 

Becker M, Frauenrath T, Hezel F, Krombach GA, Kremer U, Koppers B, Butenweg C, Goemmel A, Utting JF, Schulz-Menger J, Niendorf T. Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T. Eur. Radiol. 2010, 20(6): 1344-55

 

Heinrichs U, Utting JF, Frauenrath T, Hezel F, Krombach GA, Hodenius MA, Kozerke S, Niendorf T. Myocardial T2* mapping free of distortion using susceptibility-weighted fast spin-echo imaging: a feasibility study at 1.5 T and 3.0 T. Magn. Reson. Med. 2009, 62(3): 822-8

 

Frauenrath T, Hezel F, Heinrichs U, Kozerke S, Utting JF, Kob M, Butenweg C, Boesiger P, Niendorf T. Feasibility of cardiac gating free of interference with electro-magnetic fields at 1.5 Tesla and 7.0 Tesla using an MR-stethoscope. Invest. Radiol. 2009, 44(9): 539-547

 

Gramlich M, Michely B, Krohne C, Heuser A, Erdmann B, Klaassen S, Hudson B, Magarin M, Kirchner F, Todiras M, Granzier H, Labeit S, Thierfelder L, Gerull B. Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease. J. Mol. Cell. Cardiol. 2009, 47(3): 352-8

 

Feldt S, Maschke U, Dechend R, Luft FC, Muller DN. The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J. Am Soc. Nephrol. 2008, 19(4): 743-8

 

Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burckle C, Contrepas A, Jan Danser AH, Bader M, Nguyen G, Luft FC, Muller DN. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handleregion peptide. Hypertension 2008, 51(3): 682-8

 

 

Alumni

 

Otten C, van der Ven PF, Lewrenz I, Paul S, Steinhagen A, Busch-Nentwich E, Eichhorst J, Wiesner B, Stemple D, Strähle U, Fürst DO, Abdelilah-Seyfried S. Xirp proteins mark injured skeletal muscle in zebrafish. PLos One 2012, 7(2): e31041

 

da Silva Lopes K, Pietas A, Radke MH, Gotthardt M. Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres. J. Cell. Biol. 2011, 193(4): 785-98

 

Kur E, Christa A, Veth KN, Gajera CR, Andrade-Navarro MA, Zhang J, Willer JR, Gregg RG, Abdelilah-Seyfried S, Bachmann S, Link BA, Hammes A, Willnow TE. Loss of LRP2 in zebrafish disrupts pronephric tubular clearance but not forebrain development. Dev. Dyn. 2011, 240(6): 1567-77

 

Zhang J, Piontek J, Wolburg H, Piehl C, Liss M, Otten C, Christ A, Willnow TE, Blasig IE, Abdelilah-Seyfried S. Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion. Proc. Natl. Acad. Sci. U S A 2010, 107(4): 1425-30

 

Toka O, Maass PG, Aydin A, Toka H, Hübner N, Rüschendorf F, Gong M, Luft FC, Bähring S. Childhood hypertension in autosomal-dominant hypertension with brachydactyly. Hypertension 2010, 56(5): 988-94

 

Maass PG, Wirth J, Aydin A, Rump A, Stricker S, Tinschert S, Otero M, Tsuchimochi K, Goldring MB, Luft FC, Bähring S. A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E. Hum. Mol. Genet. 2010, 19(5): 848-60

 

Shi Y, Chen C, Lisewski U, Wrackmeyer U, Radke M, Westermann D, Sauter M, Tschöpe C, Poller W, Klingel K, Gotthardt M. J. Am. Coll. Cardiol. 2009, 53(14): 1219-26

 

Ottenhejm CA, Hidalgo C, Rost K, Gotthardt M, Granzier H. Altered contractility of skeletal muscle in mice deficient in titin's M-band region. J. Mol. Biol. 2009, 393(1): 10-26

 

Granzier HL, Radke MH, Peng J, Westermann D, Nelson OL, Rost K, King NM, Yu Q, Tschöpe C, McNabb M, Larson DF, Labeit S, Gotthardt M. Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction. Circ. Res. 2009, 105(6): 557-64

 

Rohr S, Otten S, Abelilah-Seyfried S. Alymmetric involution of the myocardial field drives heart tube formation in zebrafish. Circ. Res. 2008, 102(2): e12-9

 

Lisewski U, Shi Y, Wrackmeyer U, Fischer R, Chen C, Schirdewan A, Jüttner R, Rathjen F, Poller W, Radke MH, Gotthardt M. The tight junction protein CAR regulates cardiac conduction and cell-cell communication. J. Exp. Med. 2008, 205(10): 2369-79

 

Bähring S, Kann M, Neuenfeld Y, Gong M, Chitayat D, Toka HR, Toka O, Plessis G, Maass P, Rauch A, Aydin A, Luft FC. Inversion region for hypertension and brachydactyly on chromosome 12p features multiple splicing and noncoding RNA. Hypertension 2008, 51(2): 426-31

 

Cui S, Otten C, Rohr S, Abdelilah-Seyfried S, Link BA. Analysis of aPKClambda and aPKCzeta reveals multiple and redundant functions during vertebrate retinogenesis. Mol. Cell. Neurosci. 2007, 34(3): 431-44

News

April 2016
New TransCard Student
Please welcome Laura M. Mueller (Spagnoli lab), who has joinded the TransCard program on April 18th, 2016.

February 2016
Research Highlight for Holger Gerhardt
It is blood pressure that drives the opening of small capillaries during angiogenesis. A team of researchers led by Holger Gerhardt observed the process for the first time and published their findings in Nature Cell Biology. If you are interested please click here to enter the research highlights.
New TransCard Students
Please welcome Valentin Schneider (Huebner lab), Judith Huettemeister (Gotthardt lab), and Marta Bastos de Oliveira (Gerhardt lab), who have joined the TransCard program in February 2016.

January 2016
New TransCard Student
Please welcome Kristin Kraeker (Dechend/Mueller lab), who has joined the TransCard program on January 28th, 2016.

Application Fall 2016

Contact

Dr. Inka Gotthardt
Max Delbrück Center for Molecular Medicine
Robert-Rössle-Str 10
D-13125 Berlin

Phone: +49 30 9406 4258
Fax: +49 30 9406 2170
transcard@mdc-berlin.de