Publications



2017

Mossadegh-Keller N.; Gentek R.; Gimenez G.; Bigot S.; Mailfert S.; Sieweke M.H.
Developmental origin and maintenance of distinct testicular macrophage populations
Journal of Experimental Medicine 214 (10): 2829-2041 (2017-10-02)



Imperatore F.; Maurizio J.; Vargas Aguilar S.; Busch C.J.; Favret J.; Kowenz-Leutz E.; Cathou W.; Gentek R.; Perrin P.; Leutz A.; Berruyer C.; Sieweke M.H.
SIRT1 regulates macrophage self-renewal
EMBO Journal 36 (16): 2353-2372 (2017-08-15)



2016

Herrtwich L.; Nanda I.; Evangelou K.; Nikolova T.; Horn V.; Sagar ; Erny D.; Stefanowski J.; Rogell L.; Klein C.; Gharun K.; Follo M.; Seidl M.; Kremer B.; Muenke N.; Senges J.; Fliegauf M.; Aschman T.; Pfeifer D.; Sarrazin S.; Sieweke M.H.; Wagner D.; Dierks C.; Haaf T.; Ness T.; Zaiss M.M.; Voll R.E.; Deshmukh S.D.; Prinz M.; Goldmann T.; Hoelscher C.; Hauser A.E.; Lopez-Contreras A.J.; Gruen D.; Gorgoulis V.; Diefenbach A.; Henneke P.; Triantafyllopoulou A.
DNA damage signaling instructs polyploid macrophage fate in granulomas
Cell 167 (5): 1264-1280.e18 (2016-11-17)



Chu V.T.; Graf R.; Wirtz T.; Weber T.; Favret J.; Li X.; Petsch K.; Tran N.T.; Sieweke M.H.; Berek C.; Kuehn R.; Rajewsky K.
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519 (2016-11-01)



Kandalla P.K.; Sarrazin S.; Molawi K.; Berruyer C.; Redelberger D.; Favel A.; Bordi C.; de Bentzmann S.; Sieweke M.H.
M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation
Journal of Experimental Medicine 213 (11): 2269-2279 (2016-10-10)



Matcovitch-Natan O.; Winter D.R.; Giladi A.; Vargas Aguilar S.; Spinrad A.; Sarrazin S.; Ben-Yehuda H.; David E.; Zelada Gonzalez F.; Perrin P.; Keren-Shaul H.; Gury M.; Lara-Astaiso D.; Thaiss C.A.; Cohen M.; Bahar Halpern K.; Baruch K.; Deczkowska A.; Lorenzo-Vivas E.; Itzkovitz S.; Elinav E.; Sieweke M.H.; Schwartz M.; Amit I.
Microglia development follows a stepwise program to regulate brain homeostasis
Science 353 (6301): aad8670 (2016-08-19)



Sarrazin S.; Sieweke M.H.
Eosinophils and mast cells: a lineage apart
Nature Immunology 17 (6): 609-611 (2016-05-19)



Soucie E.L.; Weng Z.; Geirsdottir L.; Molawi K.; Maurizio J.; Fenouil R.; Mossadegh-Keller N.; Gimenez G.; VanHille L.; Beniazza M.; Favret J.; Berruyer C.; Perrin P.; Hacohen N.; Andrau J.C.; Ferrier P.; Dubreuil P.; Sidow A.; Sieweke M.H.
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells
Science 351 (6274): aad5510 (2016-02-12)



2015

Giordano M.; Henin C.; Maurizio J.; Imbratta C.; Bourdely P.; Buferne M.; Baitsch L.; Vanhille L.; Sieweke M.H.; Speiser D.E.; Auphan-Anezin N.; Schmitt-Verhulst A.M.; Verdeil G.
Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion
EMBO Journal 34 (15): 2042-2058 (2015-08-04)



Molawi K.; Sieweke M.H.
Monocytes compensate Kupffer cell loss during bacterial infection
Immunity 42 (1): 10-12 (2015-01-20)



Sieweke M.H.
Waddington's Valleys and Captain Cook's Islands
Cell Stem Cell 16 (1): 7-8 (2015-01-08)



Alvarez-Errico D.; Vento-Tormo R.; Sieweke M.; Ballestar E.
Epigenetic control of myeloid cell differentiation, identity and function
Nature Reviews Immunology 15 (1): 7-17 (2015-01)



2014

Gentek R.; Molawi K.; Sieweke M.H.
Tissue macrophage identity and self-renewal
Immunological Reviews 262 (1): 56-73 (2014-11)



Molawi K.; Wolf Y.; Kandalla P.K.; Favret J.; Hagemeyer N.; Frenzel K.; Pinto A.R.; Klapproth K.; Henri S.; Malissen B.; Rodewald H.R.; Rosenthal N.A.; Bajenoff M.; Prinz M.; Jung S.; Sieweke M.H.
Progressive replacement of embryo-derived cardiac macrophages with age
Journal of Experimental Medicine 211 (11): 2151-2158 (2014-10-20)



Pogenberg V.; Consani Textor L.; Vanhille L.; Holton S.J.; Sieweke M.H.; Wilmanns M.
Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference
Structure 22 (3): 466-477 (2014-03-04)



2013

Sieweke M.H.; Allen J.E.
Beyond stem cells: self-renewal of differentiated macrophages
Science 342 (6161): 1242974 (2013-11-22)



Mossadegh-Keller N.; Sarrazin S.; Kandalla P.K.; Espinosa L.; Stanley E.R.; Nutt S.L.; Moore J.; Sieweke M.H.
M-CSF instructs myeloid lineage fate in single haematopoietic stem cells
Nature 497 (7448): 239-243 (2013-05-09)



Molawi K.; Sieweke M.H.
Transcriptional control of macrophage identity, self-renewal, and function
Advances in Immunology 120: 269-300 (2013)