MRI measurements within the National Cohort

Magnetic resonance imaging (MRI) permits comprehensive imaging using highly standardized protocols without ionizing radiation. In prospective settings, it offers the opportunity to study the relevance of preclinical morphological changes for chronic disease risk. In the German National Cohort, whole-body 3T MRI measurements are being taken from 30.000 participants.

At the MDC’s Berlin Ultrahigh Field Facility (B.U.F.F.), the Molecular Epidemiology Group, the Experimental Ultrahigh-Field MR group, and the Cardiac MRI group is conducting MRI measurements of 6.000 study participants from the three Berlin-Brandenburg study centers of the German National Cohort. The measurements will be the cornerstone for future analysis on exposure disease relationships.

References

1. Bamberg F, Kauczor HU, Weckbach S, Schlett CL, Forsting M, Ladd SC, Greiser KH, Weber MA, Schulz-Menger J, Niendorf T, Pischon T, Caspers S, Amunts K, Berger K, Bulow R, Hosten N, Hegenscheid K, Kroncke T, Linseisen J, Gunther M, Hirsch JG, Kohn A, Hendel T, Wichmann HE, Schmidt B, Jockel KH, Hoffmann W, Kaaks R, Reiser MF, Volzke H, German National Cohort MRISI. Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background. Radiology 2015:142242