Publications



2017

Ramberger E.; Dittmar G.
Tissue specific labeling in proteomics
Proteomes 5 (3): E17 (2017-07-18)



Martinez A.; Lectez B.; Ramirez J.; Popp O.; Sutherland J.D.; Urbe S.; Dittmar G.; Clague M.J.; Mayor U.
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
Molecular Neurodegeneration 12 (1): 29 (2017-04-11)



Riesner K.; Shi Y.; Jacobi A.; Kraeter M.; Kalupa M.; McGearey A.; Mertlitz S.; Cordes S.; Schrezenmeier J.F.; Mengwasser J.; Westphal S.; Perez-Hernandez D.; Schmitt C.; Dittmar G.; Guck J.; Penack O.
Initiation of acute graft-versus-host disease by angiogenesis
Blood 129 (14): 2021-2032 (2017-04-06)



Pamudurti NR.; Bartok O.; Jens M.; Ashwal-Fluss R.; Stottmeister C.; Ruhe L.; Hanan M.; Wyler E.; Perez-Hernandez D.; Ramberger E.; Shenzis S.; Samson M.; Dittmar G.; Landthaler M.; Chekulaeva M.; Rajewsky N.; Kadener S.
Translation of circRNAs
Molecular Cell 66 (1): 9-21.e7 (2017-04-06)



2016

Viola J.R.; Lemnitzer P.; Jansen Y.; Csaba G.; Winter C.; Neideck C.; Silvestre-Roig C.; Dittmar G.; Doering Y.; Drechsler M.; Weber C.; Zimmer R.; Cenac N.; Soehnlein O.
Resolving lipid mediators maresin 1 and resolvin D2 prevent atheroprogression in mice
Circulation Research 119 (9): 1030-1038 (2016-10-14)



Eccles R.L.; Czajkowski M.T.; Barth C.; Mueller P.M.; McShane E.; Grunwald S.; Beaudette P.; Mecklenburg N.; Volkmer R.; Zuehlke K.; Dittmar G.; Selbach M.; Hammes A.; Daumke O.; Klussmann E.; Urbe S.; Rocks O.
Bimodal antagonism of PKA signalling by ARHGAP36
Nature Communications 7: 12963 (2016-10-07)



Thomas J.J.; Abed M.; Heuberger J.; Novak R.; Zohar Y.; Beltra-Lopez A.P.; Trausch-Azar J.S.; Ilagan M.X.G.; Benhamou D.; Dittmar G.; Kopan R.; Birchmeier W.; Schwartz A.L.; Orian A.
RNF4-dependent oncogene activation by protein stabilization
Cell Reports 16 (12): 3388-3400 (2016-09-20)



Weber A.; Cohen I.; Popp O.; Dittmar G.; Reiss Y.; Sommer T.; Ravid T.; Jarosch E.
Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase
Molecular Cell 63 (5): 827-839 (2016-09-01)



Nogai A.; Shi Y.; Perez-Hernandez D.; Cordes S.; Mengwasser J.; Mertlitz S.; Riesner K.; Kalupa M.; Erdmann J.H.; Ziebig R.; Dittmar G.; Penack O.
Organ siderosis and hemophagocytosis during acute graft-versus-host disease
Haematologica 101 (8): e344-e346 (2016-08)



Sapcariu S.C.; Kanashova T.; Dilger M.; Diabate S.; Oeder S.; Passig J.; Radischat C.; Buters J.; Sippula O.; Streibel T.; Paur H.R.; Schlager C.; Muelhopt S.; Stengel B.; Rabe R.; Harndorf H.; Krebs T.; Karg E.; Groeger T.; Weiss C.; Dittmar G.; Hiller K.; Zimmermann R.
Metabolic profiling as well as stable isotope assisted metabolic and proteomic analysis of RAW 264.7 macrophages exposed to ship engine aerosol emissions: different effects of heavy fuel Oil and refined diesel fuel
PLoS ONE 11 (6): e0157964 (2016-06-27)



Lodka D.; Pahuja A.; Geers-Knoerr C.; Scheibe R.; Nowak M.; Hamati J.; Koehncke C.; Purfuerst B.; Kanashova T.; Schmidt S.; Glass D.J.; Morano I.; Heuser A.; Kraft T.; Bassel-Duby R.; Olson E.N.; Dittmar G.; Sommer T.; Fielitz J.
Muscle RING-finger 2 and 3 maintain striated-muscle structure and function
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180 (2016-05)



Meiser J.; Delcambre S.; Wegner A.; Jaeger C.; Ghelfi J.; D'Herouel A.F.; Dong X.; Weindl D.; Stautner C.; Nonnenmacher Y.; Michelucci A.; Popp O.; Giesert F.; Schildknecht S.; Kraemer L.; Schneider J.G.; Woitalla D.; Wurst W.; Skupin A.; Weisenhorn D.M.V.; Krueger R.; Leist M.; Hiller K.
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
Neurobiology of Disease 89: 112-125 (2016-05)



Krause C.J.; Popp O.; Thirunarayanan N.; Dittmar G.; Lipp M.; Mueller G.
MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR
Oncotarget 7 (9): 10414-10432 (2016-03-01)



Beaudette P.; Popp O.; Dittmar G.
Proteomic techniques to probe the ubiquitin landscape
Proteomics 16 (2): 273-287 (2016-01)



2015

Ramirez J.; Martinez A.; Lectez B.; Lee S.Y.; Franco M.; Barrio R.; Dittmar G.; Mayor U.
Proteomic analysis of the ubiquitin landscape in the drosophila embryonic nervous system and the adult photoreceptor cells
PLoS ONE 10 (10): e0139083 (2015-10-13)



Jerke U.; Perez Hernandez D.; Beaudette P.; Korkmaz B.; Dittmar G.; Kettritz R.
Neutrophil serine proteases exert proteolytic activity on endothelial cells
Kidney International 88 (4): 764-775 (2015-10)



Tuorto F.; Herbst F.; Alerasool N.; Bender S.; Popp O.; Federico G.; Reitter S.; Liebers R.; Stoecklin G.; Groene H.J.; Dittmar G.; Glimm H.; Lyko F.
The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis
EMBO Journal 34 (18): 2350-2362 (2015-09-14)



Kanashova T.; Popp O.; Orasche J.; Karg E.; Harndorf H.; Stengel B.; Sklorz M.; Streibel T.; Zimmermann R.; Dittmar G.
Differential proteomic analysis of mouse macrophages exposed to adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation workflow
Analytical and Bioanalytical Chemistry 407 (20): 5965-5976 (2015-08)



Oeder S.; Kanashova T.; Sippula O.; Sapcariu S.C.; Streibel T.; Arteaga-Salas J.M.; Passig J.; Dilger M.; Paur H.R.; Schlager C.; Muelhopt S.; Diabate S.; Weiss C.; Stengel B.; Rabe R.; Harndorf H.; Torvela T.; Jokiniemi J.K.; Hirvonen M.R.; Schmidt-Weber C.; Traidl-Hoffmann C.; BeruBe K.A.; Wlodarczyk A.J.; Prytherch Z.; Michalke B.; Krebs T.; Prevot A.S.H.; Kelbg M.; Tiggesbaeumker J.; Karg E.; Jakobi G.; Scholtes S.; Schnelle-Kreis J.; Lintelmann J.; Matuschek G.; Sklorz M.; Klingbeil S.; Orasche J.; Richthammer P.; Mueller L.; Elsasser M.; Reda A.; Groeger T.; Weggler B.; Schwemer T.; Czech H.; Rueger C.P.; Abbaszade G.; Radischat C.; Hiller K.; Buters J.T.M.; Dittmar G.; Zimmermann R.
Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions
PLoS ONE 10 (6): e0126536 (2015-06-03)



Dittmar G.; Selbach M.
SILAC for biomarker discovery
Proteomics Clinical Applications 9 (3-4): 301-306 (2015-04)



Kaps S.; Kettner K.; Migotti R.; Kanashova T.; Krause U.; Roedel G.; Dittmar G.; Kriegel T.M.
Protein kinase Ymr291w/Tda1 is essential for glucose signaling in Saccharomyces cerevisiae on the level of hexokinase isoenzyme ScHxk2 phosphorylation
Journal of Biological Chemistry 290 (10): 6243-6255 (2015-03-06)



Hu F.; a Dzaye O.D.; Hahn A.; Yu Y.; Scavetta R.J.; Dittmar G.; Kaczmarek A.K.; Dunning K.R.; Ricciardelli C.; Rinnenthal J.L.; Heppner F.L.; Lehnardt S.; Synowitz M.; Wolf S.A.; Kettenmann H.
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling
Neuro-Oncology 17 (2): 200-210 (2015-02)



2014

Yilmaz Z.B.; Kofahl B.; Beaudette P.; Baum K.; Ipenberg I.; Weih F.; Wolf J.; Dittmar G.; Scheidereit C.
Quantitative dissection and modeling of the NF-{kappa}B p100-p105 module reveals interdependent precursor proteolysis
Cell Reports 9 (5): 1756-1769 (2014-12-11)



Min M.; Mayor U.; Dittmar G.; Lindon C.
Using in vivo-biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells
Molecular & Cellular Proteomics 13 (9): 2411-2425 (2014-09)



Sapcariu S.C.; Kanashova T.; Weindl D.; Ghelfi J.; Dittmar G.; Hiller K.
Simultaneous extraction of proteins and metabolites from cells in culture
MethodsX 1 (1): 74-80 (2014-07-18)



Lectez B.; Migotti R.; Lee S.Y.; Ramirez J.; Beraza N.; Mansfield B.; Sutherland J.; Martinez-Chantar M.L.; Dittmar G.; Mayor U.
Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin
Journal of Proteome Research 13 (6): 3016-3026 (2014-06-06)



Huegel S.; Depping R.; Dittmar G.; Rother F.; Cabot R.; Sury M.D.; Hartmann E.; Bader M.
Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach
Molecular & Cellular Proteomics 13 (5): 1286-1298 (2014-05-01)



Raule M.; Cerruti F.; Benaroudj N.; Migotti R.; Kikuchi J.; Bachi A.; Navon A.; Dittmar G.; Cascio P.
PA28{alpha}{beta} reduces size and increases hydrophilicity of 20S immunoproteasome peptide products
Chemistry & Biology 21 (4): 470-480 (2014-04-24)



Langhans C.; Weber-Carstens S.; Schmidt F.; Hamati J.; Kny M.; Zhu X.; Wollersheim T.; Koch S.; Krebs M.; Schulz H.; Lodka D.; Saar K.; Labeit S.; Spies C.; Hubner N.; Spranger J.; Spuler S.; Boschmann M.; Dittmar G.; Butler-Browne G.; Mouly V.; Fielitz J.
Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy
PLoS ONE 9 (3): e92048 (2014-03-20)



Mates N.; Kettner K.; Heidenreich F.; Pursche T.; Migotti R.; Kahlert G.; Kuhlisch E.; Breunig K.D.; Schellenberger W.; Dittmar G.; Hoflack B.; Kriegel T.M.
Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis
Molecular & Cellular Proteomics 13 (3): 860-875 (2014-03-01)



2013

de Juan-Sanz J.; Nunez E.; Villarejo-Lopez L.; Perez-Hernandez D.; Rodriguez-Fraticelli A.E.; Lopez-Corcuera B.; Vazquez J.; Aragon C.
Na+/K+-ATPase is a new interacting partner for the neuronal glycine transporter GlyT2 that downregulates its expression in vitro and in vivo
Journal of Neuroscience 33 (35): 14269-14281 (2013-08-28)



Bagola K.; von Delbrueck M.; Dittmar G.; Scheffner M.; Ziv I.; Glickman M.H.; Ciechanover A.; Sommer T.
Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases
Molecular Cell 50 (4): 528-539 (2013-05-23)



Mueller-Rischart A.K.; Pilsl A.; Beaudette P.; Patra M.; Hadian K.; Funke M.; Peis R.; Deinlein A.; Schweimer C.; Kuhn P.H.; Lichtenthaler S.F.; Motori E.; Hrelia S.; Wurst W; Truembach D.; Langer T.; Krappmann D.; Dittmar G.; Tatzelt J.; Winklhofer K.F.
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
Molecular Cell 49 (5): 908-921 (2013-03-07)



Anton F.; Dittmar G.; Langer T.; Escobar-Henriques M.
Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways
Molecular Cell 49 (3): 487-498 (2013-02-07)



2012

Kirchner F.; Schuetz A.; Boldt L.H.; Martens K.; Dittmar G.; Haverkamp W.; Thierfelder L.; Heinemann U.; Gerull B.
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations
Circulation Cardiovascular Genetics 5 (4): 400-411 (2012-08-01)



Stock K.; Kumar J.; Synowitz M.; Petrosino S.; Imperatore R.; Smith E.S.J.; Wend P.; Purfuerst B.; Nuber U.A.; Gurok U.; Matyash V.; Waelzlein J.H.; Chirasani S.R.; Dittmar G.; Cravatt B.F.; Momma S.; Lewin G.R.; Ligresti A.; De Petrocellis L.; Cristino L.; Di Marzo V.; Kettenmann H.; Glass R.
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1
Nature Medicine 18 (8): 1232-1238 (2012-08)



2011

Kruegel U.; Robison B.; Dange T.; Kahlert G.; Delaney J.R.; Kotireddy S.; Tsuchiya M.; Tsuchiyama S.; Murakami C.J.; Schleit J.; Sutphin G.; Carr D.; Tar K.; Dittmar G.; Kaeberlein M.; Kennedy B.K.; Schmidt M.
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae
PLoS Genetics 7 (9): e1002253 (2011-09)



Paasch U.; Heidenreich F.; Pursche T.; Kuhlisch E.; Kettner K.; Grunewald S.; Kratzsch J.; Dittmar G.; Glander H.J.; Hoflack B.; Kriegel T.M.
Identification of increased amounts of eppin protein complex components in sperm cells of diabetic and obese individuals by difference gel electrophoresis
Molecular & Cellular Proteomics 10 (8): M110.007187 (2011-08)



Marek M.; Milles S.; Schreiber G.; Daleke D.L.; Dittmar G.; Herrmann A.; Mueller P.; Pomorski T.G.
The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity
Journal of Biological Chemistry 286 (24): 21835-21843 (2011-06-17)



Schwanhaeusser B.; Busse D.; Li N.; Dittmar G.; Schuchhardt J.; Wolf J.; Chen W.; Selbach M.
Global quantification of mammalian gene expression control
Nature 473 (7347): 337-342 (2011-05-19)



Jerke U.; Rolle S.; Dittmar G.; Bayat B.; Santoso S.; Sporbert A.; Luft F.C.; Kettritz R.
Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation
Journal of Biological Chemistry 286 (9): 7070-7081 (2011-03-04)



Pless O.; Kowenz-Leutz E.; Dittmar G.; Leutz A.
A differential proteome screening system for post-translational modification-dependent transcription factor interactions
Nature Protocols 6 (3): 359-364 (2011-02)



Leutz A.; Pless O.; Lappe M.; Dittmar G.; Kowenz-Leutz E.
Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs
Transcription 2 (1): 3-8 (2011-01)



2010

Hinz M.; Stilmann M.; Coel Arslan S.; Khanna K.K.; Dittmar G.; Scheidereit C.
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
Molecular Cell 40 (1): 63-74 (2010-10-08)



Stolz A.; Ertych N.; Kienitz A.; Vogel C.; Schneider V.; Fritz B.; Jacob R.; Dittmar G.; Weichert W.; Petersen I.; Bastians H.
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells
Nature Cell Biology 12 (5): 492-499 (2010-05)



Kowenz-Leutz E.; Pless O.; Dittmar G.; Knoblich M.; Leutz A.
Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code
EMBO Journal 29 (6): 1105-1115 (2010-03-17)



2009

Dittmar G.; Selbach M.
Novel insights into proteomic technologies and their clinical perspective
Genome Medicine 1 (5): 53 (2009-05-21)



Schwanhaeusser B.; Gossen M.; Dittmar G.; Selbach M.
Global analysis of cellular protein translation by pulsed SILAC
Proteomics 9 (1): 205-209 (2009-01)



Guenther U.P.; Handoko L.; Varon R.; Stephani U.; Tsao C.Y.; Mendell J.R.; Luetzkendorf S.; Huebner C.; von Au K.; Jablonka S.; Dittmar G.; Heinemann U.; Schuetz A.; Schuelke M.
Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease
Journal of Molecular Medicine 87 (1): 31-41 (2009-01)



2006

Sommer T.; Dittmar G.
Ubiquitination
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1964-1968 (2006)



2004

Wilkinson C.R.; Dittmar G.A.; Ohi M.D.; Uetz P.; Jones N.; Finley D.
Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast
Current Biology 14: 2283-2288 (2004-12-29)



2002

Elsasser S.; Gali R.R.; Schwickart M.; Larsen C.N.; Leggett D.S.; Mueller B.; Feng M.T.; Tuebing F.; Dittmar G.A.G.; Finley D.
Proteasome subunit Rpn1 binds ubiquitin-like protein domains
Nature Cell Biology 4: 725-730 (2002-09-01)



Dittmar G.A.G.; Wilkinson C.R.M.; Jedrzejewski P.T.; Finley D.
Role of a ubiquitin-like modification in polarized morphogenesis
Science 295: 2442-2446 (2002-03-29)