Publications



2016

Nasrallah R.; Fast E.M.; Solaimani P.; Knezevic K.; Eliades A.; Patel R.; Thambyrajah R.; Unnikrishnan A.; Thoms J.; Beck D.; Vink C.S.; Smith A.; Wong J.; Shepherd M.; Kent D.; Roychoudhuri R.; Paul F.; Klippert J.; Hammes A.; Willnow T.; Goettgens B.; Dzierzak E.; Zon L.I.; Lacaud G.; Kouskoff V.; Pimanda J.E.
Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes
Blood 128 (15): 1928-1939 (2016-10-13)



Eccles R.L.; Czajkowski M.T.; Barth C.; Mueller P.M.; McShane E.; Grunwald S.; Beaudette P.; Mecklenburg N.; Volkmer R.; Zuehlke K.; Dittmar G.; Selbach M.; Hammes A.; Daumke O.; Klussmann E.; Urbe S.; Rocks O.
Bimodal antagonism of PKA signalling by ARHGAP36
Nature Communications 7: 12963 (2016-10-07)



2015

Christ A.; Christa A.; Klippert J.; Eule J.C.; Bachmann S.; Wallace V.A.; Hammes A.; Willnow T.E.
LRP2 acts as SHH clearance receptor to protect the retinal margin from mitogenic stimuli
Developmental Cell 35 (1): 36-48 (2015-10-12)



2014

Kur E.; Mecklenburg N.; Cabrera R.M.; Willnow T.E.; Hammes A.
LRP2 mediates folate uptake in the developing neural tube
Journal of Cell Science 127 (Pt 10): 2261-2268 (2014-05-15)



2012

Willnow T.E.; Christ A.; Hammes A.
Endocytic receptor-mediated control of morphogen signaling
Development 139 (23): 4311-4319 (2012-12-01)



Christ A.; Christa A.; Kur E.; Lioubinski O.; Bachmann S.; Willnow T.E.; Hammes A.
LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals
Developmental Cell 22 (2): 268-278 (2012-02-14)



2011

Kur E.; Christa A.; Veth K.N.; Gajera C.R.; Andrade-Navarro M.A.; Zhang J.; Willer J.R.; Gregg R.G.; Abdelilah-Seyfried S.; Bachmann S.; Link B.A.; Hammes A.; Willnow T.E.
Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development
Developmental Dynamics 240 (6): 1567-1577 (2011-06)



2010

Chiu-Ugalde J.; Theilig F.; Behrends T.; Drebes J.; Sieland C.; Subbarayal P.; Koehrle J.; Hammes A.; Schomburg L.; Schweizer U.
Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain
Biochemical Journal 431 (1): 103-111 (2010-10-01)



Christ A.; Terryn S.; Schmidt V.; Christensen E.I.; Huska M.R.; Andrade-Navarro M.A.; Huebner N.; Devuyst O.; Hammes A.; Willnow T.E.
The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo
Kidney International 78 (5): 473-477 (2010-09)



Gajera C.R.; Emich H.; Lioubinski O.; Christ A.; Beckervordersandforth-Bonk R.; Yoshikawa K.; Bachmann S.; Christensen E.I.; Goetz M.; Kempermann G.; Peterson A.S.; Willnow T.E.; Hammes A.
LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche
Journal of Cell Science 123 (Pt 11): 1922-1930 (2010-06-01)



Joutel A.; Monet-Lepretre M.; Gosele C.; Baron-Menguy C.; Hammes A.; Schmidt S.; Lemaire-Carrette B.; Domenga V.; Schedl A.; Lacombe P.; Huebner N.
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease
Journal of Clinical Investigation 120 (2): 433-445 (2010-02-01)



2008

Willnow T.E.; Hammes A.; Nykjaer A.
Endocytosis of sex steroids: The hypothesis of free hormones revisited
Annales d'Endocrinologie 69 (2): 101-102 (2008-04)



2007

Willnow T.E.; Hammes A.; Eaton S.
Lipoproteins and their receptors in embryonic development: more than cholesterol clearance
Development 134 (18): 3239-3249 (2007-09)



2005

Hammes A.; Andreassen T.K.; Spoelgen R.; Raila J.; Huebner N.; Schulz H.; Metzger J.; Schweigert F.J.; Luppa P.B.; Nykjaer A.; Willnow T.E.
Role of endocytosis in cellular uptake of sex steroids
Cell 122 (5): 751-762 (2005-09-09)



Spoelgen R.; Hammes A.; Anzenberger U.; Zechner D.; Andersen O.M.; Jerchow B.; Willnow T.E.
LRP2/megalin is required for patterning of the ventral telencephalon
Development 132 (2): 405-414 (2005-01-01)



2002

Vetter R.; Rehfeld U.; Reissfelder C.; Weiss W.; Wagner K.D.; Guenther J.; Hammes A.; Tschoepe C.; Dillmann W.; Paul M.
Transgenic overexpression of the sarcoplasmic reticulum Ca(2+) ATPase improves reticular Ca(2+) handling in normal and diabetic rat hearts
FASEB Journal 16 (12): 1657-1659 (2002-10)



Guo J.K.; Menke A.L.; Gubler M.C.; Clarke A.R.; Harrison D.; Hammes A.; Hastie N.D.; Schedl A.
WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis
Human Molecular Genetics 11 (6): 651-659 (2002-01-01)



2001

Hammes A.; Guo J.K.; Lutsch G.; Leheste J.R.; Landrock D.; Ziegler U.; Gubler M.C.; Schedl A.
Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation
Cell 106 (3): 319-329 (2001-08-10)



Piuhola J.; Hammes A.; Schuh K.; Neyses L.; Vuolteenaho O.; Ruskoaho H.
Overexpression of sarcolemmal calcium pump attenuates induction of cardiac gene expression in response to ET-1
American Journal of Physiology Regulatory Integrative and Comparative Physiology 281 (3): R699-R705 (2001-01-01)



1998

Hammes A.; Oberdorf-Maass S.; Rother T.; Nething K.; Gollnick F.; Linz K.W.; Meyer R.; Hu K.; Han H.; Gaudron P.; Ertl G.; Hoffmann S.; Ganten U.; Vetter R.; Schuh K.; Benkwitz C.; Zimmer H.G.; Neyses L.
Overexpression of the sarcolemmal calcium pump in the myocardium of transgenic rats
Circulation Research 83 (9): 877-888 (1998-11-02)