Advanced Light Microscopy


Aim of the Advanced Light Microscopy (ALM) technology platform is to give researchers from the MDC, the BIMSB and the ECRC on the campus Berlin-Buch access to a broad range of high-end, state-of-the-art imaging techniques and to provide scientific and methodological support to enable them to perform advanced imaging experiments and to acquire high quality microscopic images from different specimens ranging from fixed cells and tissue sections to live cells, tissues and modell organisms.


Available microscopy techniques include:

  • confocal laser scanning microscopy
  • two-photon microscopy
  • spinning disk microscopy
  • light-sheet microscopy
  • wide-field fluorescence microscopy
  • TIRF microscopy
  • stimulated emission depletion (STED) superresolution microscopy
  • fluorescence lifetime microscopy (FLIM)
  • laser-assisted microdissection and catapulting


As part of collaborative projects ALM offers expertise to find optimal image acquisition and data analysis tools for advanced imaging expereiments, i.e. by consultation about experimental design and specimen preparation, the optimisation of image acquisition conditions and customised image processing and analysis workflows.

We also contribute to the establishment of new imaging methods, i.e., light-sheet microscopy, functional imaging (FLIM-FRET) or in vivo/intravital microscopy.


ALM of the MDC is member of the steering committee and actively contributes to the GermanBioImaging, a network of german microscopists and imaging specialists.

ALM is co-funded by DFG, BIH and DZHK.


more information for internal user