Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

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Institute & Campus

Driving conversations on diversity

During the second annual Diversity Week, our community took part in a series of events. They ranged from simulating the environments of disabled people, to discussing the importance of a diverse workplace. The aim was to raise awareness and to foster a welcoming work environment for everyone.
Simon Haas
Science

BBAW Prize for cancer researcher Simon Haas

Simon Haas has been awarded the Berlin-Brandenburg Academy of Sciences and Humanities (BBAW) Prize for the promotion of cancer research, sponsored by the Monika Kutzner Foundation. His outstanding research focuses on the causes and the development of new concepts for the treatment of blood cancer.
Wissenschaftliches Gerät

Imaging synaptic vesicles in 3D

Researchers at the Max Delbrück Center have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study, published in “PNAS,” could inform therapeutic strategies for psychiatric disorders.
Wenhan Luo
Science

Studying the naked mole-rat’s mental roadmap

Wenhan Luo received a two-year Humboldt Fellowship to continue his research in Gary Lewin’s Molecular Physiology of Somatic Sensation Lab. Together, they aim to understand how naked mole rats navigate.
Symbolbild Highly Cited Researchers

Global influencers of science

Three researchers at Max Delbrück Center – Sofia Forslund, Friedemann Paul, and Nikolaus Rajewsky – are among the most Highly Cited Researchers in the world in 2024, making the list two years in a row. Germany ranks fourth of countries and regions, behind the U.S., mainland China and the U.K.
woman with a scientific chip
Science

The innovator

As Scientific Director of Max Delbrück Center, Maike Sander is driving a bold shift toward interdisciplinary research to address the health challenges of our time. As a diabetes researcher, her next frontier is to use organ-on-a-chip technologies to build more accurate models of the human pancreas.
2D map of gene expression in the metastatic lymph node
Science

Beyond ChatGPT: Foundation models for research

Foundation models are complex AI applications with enormous potential. Trained on vast datasets from medicine, climate, or material science, they can uncover new relationships and make predictions. Helmholtz is supporting this pioneering work, with €5.55 million going to the Max Delbrück Center.
woman
Science

From research to application

The Max Delbrück Center proudly welcomes Dr. Nevine Shalaby as the new Head of the Innovation and Entrepreneurship Department. With a rich background in genetics and industry, she aims to drive research impact, foster spin-offs, and strengthen industry partnerships, aligned with the Strategy 2030.
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Cancer risk linked to p53 in Ulcerative Colitis

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study, published in “Science Advances,” suggests a potential new drug target to stop disease progression to cancer.

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Publications

Simplified preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase

Clin Chem Lab Med

Concurrent profiling of localized transcriptome and RNA dynamics in neurons by spatial SLAMseq

Methods Mol Biol

In vitro testing of drug response in primary multiple myeloma cells using a microwell-based technology

Leuk Res

Generation of two isogenic human iPSC lines (ZIPi013-B-1, ZIPi013-B-2) carrying a CRISPR/Cas9-mediated deletion of TRPM4

Stem Cell Res

All Publications