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2 Independent Junior Group Leader Positions (f/m/d) in Computational and/or Experimental Medical Systems Biology

professor or independent group leader

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) is one of the world’s leading biomedical research institutions. Max Delbrück, a Berlin native, was a Nobel laureate and one of the founders of molecular biology. At the MDC’s locations in Berlin-Buch and Mitte, researchers from some 60 countries analyze the human system – investigating the biological foundations of life from its most elementary building blocks to systems-wide mechanisms. By understanding what regulates or disrupts the dynamic equilibrium in a cell, an organ, or the entire body, we can prevent diseases, diagnose them earlier, and stop their progression with tailored therapies. Patients should benefit as soon as possible from basic research discoveries. The MDC therefore supports spin-off creation and participates in collaborative networks. It works in close partnership with Charité – Universitätsmedizin Berlin in the jointly run Experimental and Clinical Research Center (ECRC), the Berlin Institute of Health (BIH) at Charité, and the German Center for Cardiovascular Research (DZHK). Founded in 1992, the MDC today employs 1,600 people and is funded 90 percent by the German federal government and 10 percent by the State of Berlin.

The MDC is a leading biomedical research institute dedicated to interdisciplinary research in the areas of Medical Systems Biology, Cardiovascular and Metabolic Diseases, Cancer Research, Disorders of the Nervous System, Immunology & Inflammation, and Data Science & Artificial Intelligence. The Berlin Institute for Medical Systems Biology (BIMSB) is a strategic expansion of the MDC and currently hosts 26 labs working at the interface between computational and experimental biology. Since early 2019, MDC/BIMSB is located in a new research building at the heart of Berlin on the Humboldt University campus and in close proximity to the Charité - Universitätsmedizin Berlin, the Berlin Institute for Health, the Deutsches Rheuma-Forschungszentrum Berlin (DRFZ) and the Max Planck Institute for Infection Biology (MPI-IB). Recently we have established exciting new and clinically relevant interactions with our new neighbors.
We are inviting applications from exceptional scientists (f/m/d) in the fields of computational and/or experimental medical systems biology. Desired areas of expertise include, but are not limited to understanding tissue organization and homeostasis (e. g. cell-cell communication, spatial transcriptomics, organoid models), cell and tissue engineering (e. g. CRISPR/Cas-based base and epigenome editing, engineering of cell circuits, controlling therapeutic activity in space and time), theoretical population dynamics, RNA therapeutics, or technology development in areas such as single cell screening or nanoengineering. Candidates using or developing quantitative high-throughput technologies, machine learning, single-cell or single-molecule approaches, as well as model organisms or human disease models are especially encouraged to apply.

Job Description

The successful candidates (f/m/d) are expected to conduct visionary independent research, acquire extramural funding, and engage in collaborative projects with experimental and computational groups and state-of-the-art technology platforms at the MDC and other research institutions, universities and hospitals in Berlin. The MDC will provide access to cluster and GPU compute facilities as well as support with administrative tasks (administrative assistance, 10 hrs/week), during onboarding, and for career development.

For further information, please visit our website . Enquiries about the positions and perspectives should be addressed to Nikolaus Rajewsky (


Experience in working in an interdisciplinary environment is desirable and a track record of highly successful post-doctoral research or, in exceptional cases, outstanding doctoral research is essential.

We offer

  • International working environment with communication in English and German
  • Interesting career opportunities and a comprehensive range of qualification and further training opportunities
  • Compatibility of family and career certified by the berufundfamilie audit
  • Varied support for "New Berliners" (Welcome & Family Office)
  • Company health management with fitness center

The MDC is committed to diversity and actively supports equal opportunities for all employees regardless of their origin, religion, ideology, disability, age or sexual identity. We look forward to applications from people who are open-minded and enjoy working in joint teams. The MDC is certified by the “work and family” audit and provides an inclusive and family friendly environment. Applications from women are explicitly encouraged.

Further Information:


Application Period:
February 17, 2022

MDC Berlin-Mitte

Our attractive start-up package includes your salary (according to the German public salaries, TVöD Bund/Ost, depending on the personal requirements, up to the fee group EG15), staff of one post-doc, one PhD student, one technical staff employee, annual consumables, start-up investment, and opportunities to recruit centrally funded students from the MDC´s international PhD fellowship programs.

Employment volume:
Full Time

Desired starting date:
October 01, 2022

Fixed Term
We offer funding for 5 years with an option for extension of 4 years upon evaluation.

Nikolaus Rajewsky

Parity and equal status:
The MDC is committed to diversity and actively promotes equal opportunities for all employees regardless of their origin, religion, ideology, health impairment, age or sexual identity. We look forward to receiving applications from open-minded people who enjoy working in diverse teams. Applications from severely disabled persons will be given special consideration.

Applications should be uploaded to the MDC application portal ( by 17 February, 2022 including cover letter, curriculum vitae, list of publications, and an outline of present and future research plans (3-5 pages are recommended). Please submit your application in a single pdf file, maximum size 8 MB. Please request 2 reference letters to be sent to within the application deadline.

Apply now