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Engineer, Life Sciences

engineer

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) is one of the world’s leading biomedical research institutions. Max Delbrück, a Berlin native, was a Nobel laureate and one of the founders of molecular biology. At the MDC’s locations in Berlin-Buch and Mitte, researchers from some 60 countries analyze the human system – investigating the biological foundations of life from its most elementary building blocks to systems-wide mechanisms. By understanding what regulates or disrupts the dynamic equilibrium in a cell, an organ, or the entire body, we can prevent diseases, diagnose them earlier, and stop their progression with tailored therapies. Patients should benefit as soon as possible from basic research discoveries. The MDC therefore supports spin-off creation and participates in collaborative networks. It works in close partnership with Charité – Universitätsmedizin Berlin in the jointly run Experimental and Clinical Research Center (ECRC ), the Berlin Institute of Health (BIH) at Charité, and the German Center for Cardiovascular Research (DZHK). Founded in 1992, the MDC today employs 1,600 people and is funded 90 percent by the German federal government and 10 percent by the State of Berlin.

The group of Dr. Ilaria Piazza in Berlin-Buch is looking for a lab manager with specific technical expertise in mass spectrometric protein analysis of biological samples.

Job Description

  • Development of new and optimization of existing data acquisition methods for the quantitative analysis of proteins abundances, modifications and interactions by mass spectrometry
  • Knowledge of data independent acquisition methods (DIA) for mass spectrometry-based proteomics and relative software for data acquisition is desirable
  • Routine quality checks, maintenance and repair of simple malfunctions of UHPLC instruments, mass spectrometers and pipetting robots
  • Coordination of major repair work on sample preparation and measurement equipment in collaboration with engineers
  • Assist with data analysis of technical and biological projects and present information within the group
  • General laboratory organization (ordering, preparation of reagents, protocol + database management, etc.)
  • Assisting new lab members for the organization of cell culture and molecular biology tasks

Requirements

  • You have completed your training as a technical assistant or your Bachelor's/Master's degree in biology/biotechnology with good or very good results
  • Excellent knowledge of preparing biological samples for protein analysis using label-free and multiplexed (TMT) mass spectrometry
  • Experience in protein analysis (protein preparation, BCA/Bradford protein determination), excellent handling of HPLC/FPLC instruments for separation of proteins and peptides, and experience with Orbitrap (e.g. Exploris 480, Q-Exactive-HF-X) or ion mobility-TOF mass spectrometers (ex: Tims TOF-Pro2) is ideal
  • Experience in operating pipetting robots and mass spectrometers, as well as an attitude to work with complex technical equipment is an advantage
  • Familiarity with proteomics data analysis software (MaxQuant, Spectronaut, DIA-NN) would be ideal
  • High level of accuracy, reliability and accurate documentation of experimental work performed as well as strong organizational and communication skills
  • Strong motivation and sense of responsibility
  • Experience with MS Office, especially spreadsheets in Excel, is required
  • Very good knowledge of English and enjoyment of teamwork.

We offer

  • International working environment with communication in English and German
  • Interesting career opportunities and a comprehensive range of qualification and further training opportunities
  • Compatibility of family and career certified by the berufundfamilie audit
  • Varied support for "New Berliners" (Welcome & Family Office)
  • Company health management with fitness center

You also benefit from:

  • A remuneration in accordance with the collective agreement for the federal public service (TVöD-Bund), including additional company pension schemes
  • Flexible working hours and childcare support
  • An idyllic green campus, which is easily accessible by bicycle, public transport or car

Further Information:

Job Type:


Team:


Application Period:
December 04, 2021


Workplace:
MDC Berlin-Buch


Salary:
Die Vergütung erfolgt nach TVöD Bund, je nach Vorliegen der persönlichen Qualifikation, Erfahrung und Fähigkeiten bis zur Entgeltgruppe 12


Employment volume:
Full Time
39 Wochenstunden


Desired starting date:
January 01, 2022


Limitation:
Fixed Term
Die Stelle ist zunächst befristet für 2 Jahre, mit der Möglichkeit der Verlängerung


Contact:
Dr. Ilaria PIazza
Allosteric Proteomics
Ilaria.Piazza@mdc-berlin.de


Parity and equal status:
The MDC is committed to diversity and actively promotes equal opportunities for all employees regardless of their origin, religion, ideology, health impairment, age or sexual identity. We look forward to receiving applications from open-minded people who enjoy working in diverse teams. Applications from severely disabled persons will be given special consideration.


Application:
Please use our online portal and submit your application as one pdf file (5 MB max, including a cover letter, CV, references as well as relevant educational and degree certificates)


Apply now