MDC Lab Coats

PhD student in Bioinformatics

Job Code

10920

The Bioinformatics Group of RNA Structure and Transcriptome Regulation of Prof. I. Meyer at the BIMSB and MDC in Berlin is seeking to recruit a PhD student in Bioinformatics. We are focused on discovering new mechanisms of transcriptome regulation in diverse biological settings and have a particular interest in regulatory mechanisms mediated by RNA-structures and trans RNA-RNA interactions. To this end, we develop and apply new computational methods, algorithms and analysis pipelines to analyse large-scale data sets, in particular transcriptome data from next-generation sequencing. We design and utilise machine learning techniques, phylogenetic models and a range of probabilistic methods to tackle exciting, fundamental questions in biology. We work in close collaboration with several experimental research groups to investigate biological systems ranging from differentiating stem cells to cells during virus-infection and expect to engage in single-cell studies in the near future.

The applicant: We are looking for an enthusiastic and ambitious new team member who combines strong skills in computational method development with a keen desire to investigate exciting biological systems. The key attributes sought are the ability to work alone and as part of a team, excellent attention to detail, solid problem solving skills, and the desire to learn and improve. Furthermore, you should demonstrate your ability to communicate both biological and computational ideas (orally and in writing), time management to deadlines, and a desire to work in an international and multi-disciplinary environment.

Requirements

Essential requirements:

  • MSc or equivalent in Computer Science, Bioinformatics, Genetics or related fields (including Statistics, Bioengineering, Physics, Mathematics, Biochemistry)
  • proficiency in object-oriented programming (C++, Java) and developing software in a
Unix-based environment
  • solid background in and high enthusiasm for computational method development
  • solid background in machine learning, statistics and programming in R
  • ability to write, understand and maintain complex code
  • keen interest in investigating biological systems
  • excellent communication skills (oral and written) in English

Desired requirements:

  • previous experience of processing and analysing NGS data sets, in particular
transcriptome data
  • prior expertise with investigated biological systems (e.g. stem cells, virus infections)
  • familiarity with compute clusters and software development tools

The MDC is an equal opportunity employer and supports gender equality.

Please, send your application including all documents indicating the registration number preferably by e-mail to jobs@mdc-berlin.de as pdf files (2 files of 5 MB at the maximum) as we do not return any papers.


Salary

Re-numeration according to German TVoeD (Bund/Ost) E13 (50% in first year, 65%
in subsequent years).


Start date

as soon as possible


Limitation

The position is initially offered for 3 years, with the possibility for a further extension.


Application Period

Sunday, 25. February 2018


Further Information


Contact

For further information, contact Irmtraud Meyer ( irmtraud.meyer@mdc-berlin.de) and see www.mdc-berlin.de/meyer and www.e-rna.org.
How to apply:
(1) Please submit your complete application as a single pdf-file by email to <jobs@mdc-berlin.de> including
• cover letter
• CV
• complete set of university certificates and transcripts
• names and contact details of 3 referees
(2) Please get 3 letters of recommendation to be sent directly to
<jobs@mdc-berlin.de> by the application deadline.