Woman reading in MDC library

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in Neuroendocrinology

Increased activity of the immunoregulatory enzyme indoleamine-2,3-dioxygenase (IDO) with consecutive tryptophan depletion predicts death in patients with neuroendocrine neoplasia

R. Pschowski et al.
in eLife

Domain-swapped T cell receptors improve the safety of TCR gene therapy

M.T. Bethune et al.
in Proc Natl Acad Sci U S A

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

V.T. Chu et al.
in Mol Syst Biol

Pervasive isoform-specific translational regulation via alternative transcription start sites in mammals

X. Wang et al.
in Immunity

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity

E. Kieback et al.
in Mol Ther

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells

A. Gogol-Döring et al.
in BMC Biotechnol

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

V.T. Chu et al.