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01. Februar 2022 in Development

WASp controls oriented migration of endothelial cells to achieve functional vascular patterning

A. Rosa
W. Giese
K. Meier
S. Alt
A. Klaus-Bergmann
L.T. Edgar
E. Bartels
R. Collins
A. Szymborska
B. Coxam
M.O. Bernabeu
H. Gerhardt

18. Oktober 2021 in Hum Gene Ther

Gene therapy "Made in Germany": a historical perspective, analysis of the status quo, and recommendations for action by the German Society for Gene Therapy

H. Büning
B. Fehse
Z. Ivics
S. Kochanek
U. Koehl
C. Kupatt
C. Mussolino
D.M. Nettelbeck
A. Schambach
W. Uckert
E. Wagner
T. Cathomen

01. Februar 2021 in J Vis Exp

Electroporation-based genetic modification of primary human pigment epithelial cells using the Sleeping Beauty transposon system

S. Johnen
N. Harmening
C. Marie
D. Scherman
Z. Izsvák
Z. Ivics
P. Walter
G. Thumann

01. Mai 2020 in Redox Biol

Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery

S. Laidou
G. Alanis-Lobato
J. Pribyl
T. Raskó
B. Tichy
K. Mikulasek
M. Tsagiopoulou
J. Oppelt
G. Kastrinaki
M. Lefaki
M. Singh
A. Zink
N. Chondrogianni
F. Psomopoulos
A. Prigione
Z. Ivics
S. Pospisilova
P. Skladal
Z. Izsvák
M.A. Andrade-Navarro
S. Petrakis

12. Februar 2020 in J Cell Sci

DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis

M. van der Stoel
L. Schimmel
K. Nawaz
A.M. van Stalborch
A. de Haan
A. Klaus-Bergmann
E.T. Valent
D.S. Koenis
G.P. van Nieuw Amerongen
C.J. de Vries
V. de Waard
M. Gloerich
J.D. van Buul
S. Huveneers

01. Januar 2020 in Nucleic Acids Res

A single amino acid switch converts the sleeping beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming

L. Kesselring
C. Miskey
C. Zuliani
I. Querques
V. Kapitonov
A. Laukó
A. Fehér
A. Palazzo
T. Diem
J. Lustig
A. Sebe
Y. Wang
A. Dinnyés
Z. Izsvák
O. Barabas
Z. Ivics

13. Dezember 2019 in Mol Ther Methods Clin Dev

Preclinical evaluation of a cell-based gene therapy using the Sleeping Beauty transposon system in choroidal neovascularization

M. Hernandez
S. Recalde
L. Garcia-Garcia
J. Bezunartea
C. Miskey
S. Johnen
S. Diarra
A. Sebe
J.R. Rodriguez-Madoz
S. Pouillot
C. Marie
Z. Izsvák
D. Scherman
M. Kropp
F. Prosper
G. Thumann
Z. Ivics
A. Garcia-Layana
P. Fernandez-Robredo

27. August 2019 in Development

Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning

I. Geudens
B. Coxam
S. Alt
V. Gebala
A.C. Vion
K. Meier
A. Rosa
H. Gerhardt

01. Juni 2018 in Mol Ther Nucleic Acids

The antibiotic-free pFAR4 vector paired with the sleeping beauty transposon sSystem mediates efficient transgene delivery in human cells

M. Pastor
S. Johnen
N. Harmening
M. Quiviger
J. Pailloux
M. Kropp
P. Walter
Z. Ivics
Z. Izsvák
G. Thumann
D. Scherman
C. Marie

07. Mai 2018 in J Cell Biol

Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

A.C. Vion
S. Alt
A. Klaus-Bergmann
A. Szymborska
T. Zheng
T. Perovic
A. Hammoutene
M.B. Oliveira
E. Bartels-Klein
I. Hollfinger
P.E. Rautou
M.O. Bernabeu
H. Gerhardt