Wissenschaftliche Publikationen | Max Delbrück Center

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September 2024 / Cancer Gene Ther

Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia

L.H. Mochmann
D. Treue
M. Bockmayr
P. Silva
C. Zasada
G. Mastrobuoni
S. Bayram
M. Forbes
P. Jurmeister
S. Liebig
O. Blau
K. Schleich
B. Splettstoesser
T.M. Nordmann
E.K. von der Heide
K. Isaakidis
V. Schulze
C. Busch
H. Siddiq
C. Schlee
S. Hester
L. Fransecky
M. Neumann
S. Kempa
F. Klauschen
C.D. Baldus

22. August 2024 / Nat Commun

Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure

August 2024 / Life Sci Alliance

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

A. Waltho
O. Popp
C. Lenz
L. Pluska
M. Lambert
V. Dötsch
P. Mertins
T. Sommer

Mai 2024 / Cancers

L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling

M. Forbes
R. Kempa
G. Mastrobuoni
L. Rayman
M. Pietzke
S. Bayram
B. Arlt
A. Spruessel
H.E. Deubzer
S. Kempa

29. April 2024 / PLoS Biol

The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions

11. April 2024 / Nat Commun

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions

T. Rrustemi
K. Meyer
Y. Roske
B. Uyar
A. Akalin
K. Imami
Y. Ishihama
O. Daumke
M. Selbach

April 2024 / Life Sci Alliance

ADAM19 cleaves the PTH receptor and associates with brachydactyly type E

A. Aydin
C. Klenk
K. Nemec
Ali Işbilir
L.M. Martin
H. Zauber
T. Rrustemi
H.R. Toka
H. Schuster
M. Gong
S. Stricker
A. Bock
S. Bähring
M. Selbach
M.J. Lohse
F.C. Luft

29. Februar 2024 / BMJ Open Respir Res

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters

L.G. Teixeira Alves
M. Baumgardt
C. Langner
M. Fischer
J. Maria Adler
J. Bushe
T.C. Firsching
G. Mastrobuoni
J. Grobe
K. Hoenzke
S. Kempa
A.D. Gruber
A.C. Hocke
J. Trimpert
E. Wyler
M. Landthaler

Dezember 2023 / Stem Cell Res

Generation of an NCS1 gene knockout human induced pluripotent stem cell line using CRISPR/Cas9

S.K. Maierhof
C. Schinke
J. Cernoch
L. Hew
L.P. Bruske
V. Fernandez Vallone
K. Fischer
H. Stachelscheid
P. Huehnchen
M. Endres
S. Diecke
N.S. Telugu
W. Boehmerle

12. Oktober 2023 / Science

Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly

F.S. Rizalar
M.T. Lucht
A. Petzoldt
S. Kong
J. Sun
J.H. Vines
N.S. Telugu
S. Diecke
T. Kaas
T. Bullmann
C. Schmied
D. Löwe
J.S. King
W. Cho
S. Hallermann
D. Puchkov
S.J. Sigrist
V. Haucke