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29. Dezember 2020 in Cell Rep

USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells

P. van den Berk
C. Lancini
C. Company
M. Serresi
M.P. Sanchez-Bailon
D. Hulsman
C. Pritchard
J.Y. Song
M.J. Schmitt
E. Tanger
O. Popp
P. Mertins
I.J. Huijbers
H. Jacobs
M. van Lohuizen
G. Gargiulo
E. Citterio

23. Dezember 2020 in Cancer Discov

Phenotypic mapping of pathological crosstalk between glioblastoma and innate immune cells by synthetic genetic tracing

M.J. Schmitt
C. Company
Y. Dramaretska
I. Barozzi
A. Göhrig
S. Kertalli
M. Großmann
H. Naumann
M.P. Sanchez-Bailon
D. Hulsman
R. Glass
M. Squatrito
M. Serresi
G. Gargiulo

01. März 2021 in Int J Cancer

Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma

B. Arlt
C. Zasada
K. Baum
J. Wuenschel
G. Mastrobuoni
M. Lodrini
K. Astrahantseff
A. Winkler
J.H. Schulte
S. Finkler
M. Forbes
P. Hundsdoerfer
D. Guergen
J. Hoffmann
J. Wolf
A. Eggert
S. Kempa
H.E. Deubzer

23. Juni 2020 in Proc Natl Acad Sci U S A

Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis

T. Sommermann
T. Yasuda
J. Ronen
T. Wirtz
T. Weber
U. Sack
R. Caeser
J. Zhang
X. Li
V.T. Chu
A. Jauch
K. Unger
D.J. Hodson
A. Akalin
K. Rajewsky

27. April 2020 in Nat Commun

Integrative functional genomics decodes herpes simplex virus 1

A.W. Whisnant
C.S. Jürges
T. Hennig
E. Wyler
B. Prusty
A.J. Rutkowski
A. L'hernault
L. Djakovic
M. Göbel
K. Döring
J. Menegatti
R. Antrobus
N.J. Matheson
F.W.H. Künzig
G. Mastrobuoni
C. Bielow
S. Kempa
C. Liang
T. Dandekar
R. Zimmer
M. Landthaler
F. Grässer
P.J. Lehner
C.C. Friedel
F. Erhard
L. Dölken

19. März 2020 in Mol Cell

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription

G. Cossa
I. Roeschert
F. Prinz
A. Baluapuri
R. Silveira Vidal
C. Schülein-Völk
Y.C. Chang
C.P. Ade
G. Mastrobuoni
C. Girard
L. Wortmann
S. Walz
R. Lührmann
S. Kempa
B. Kuster
E. Wolf
D. Mumberg
M. Eilers

01. Januar 2020 in Br J Cancer

Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer

N. Berndt
A. Egners
G. Mastrobuoni
O. Vvedenskaya
A. Fragoulis
A. Dugourd
S. Bulik
M. Pietzke
C. Bielow
R. van Gassel
S.W. Olde Damink
M. Erdem
J. Saez-Rodriguez
H.G. Holzhütter
S. Kempa
T. Cramer

07. November 2019 in Genes Dev

Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat

V. Labi
S. Peng
F. Klironomos
M. Munschauer
N. Kastelic
T. Chakraborty
K. Schoeler
E. Derudder
M. Martella
G. Mastrobuoni
L.R. Hernandez-Miranda
I. Lahmann
C. Kocks
C. Birchmeier
S. Kempa
L. Quintanilla-Martinez de Fend
M. Landthaler
N. Rajewsky
K. Rajewsky

14. Juni 2019 in Commun Biol

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice

T. Ackermann
G. Hartleben
C. Müller
G. Mastrobuoni
M. Groth
B.A. Sterken
M.A. Zaini
S.A. Youssef
H.R. Zuidhof
S.R. Krauss
G. Kortman
G. de Haan
A. de Bruin
Z.Q. Wang
M. Platzer
S. Kempa
C.F. Calkhoven

30. April 2019 in Front Genet

Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors

N.T. Tran
S. Bashir
X. Li
J. Rossius
V.T. Chu
K. Rajewsky
R. Kühn