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Mai 2014 / Oncotarget RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis M. Dahlmann A. Okhrimenko P. Marcinkowski M. Osterland P. Herrmann J. Smith C.W. Heizmann P.M. Schlag U. Stein 26. August 2021 / Oncogene The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis D. Kobelt D. Perez-Hernandez C. Fleuter M. Dahlmann F. Zincke J. Smith R. Migotti O. Popp S. Burock W. Walther G. Dittmar P. Mertins U. Stein 01. August 2009 / Cell Cycle MACC1 controls Met: What a difference an Sp1 site makes U. Stein J. Smith W. Walther F. Arlt 01. Februar 2011 / Neoplasia Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis U. Stein F. Arlt J. Smith U. Sack P. Herrmann W. Walther M. Lemm I. Fichtner R.H. Shoemaker P.M. Schlag 01. November 2006 / Gastroenterology The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer U. Stein F. Arlt W. Walther J. Smith T. Waldman E.D. Harris S.D. Mertins C.W. Heizmann D. Allard W. Birchmeier P.M. Schlag R.H. Shoemaker 01. Januar 2009 / Nat Med MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis U. Stein W. Walther F. Arlt H. Schwabe J. Smith I. Fichtner W. Birchmeier P.M. Schlag 01. Mai 2007 / Biol Chem Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway K. Wenzel K. Daskalow F. Herse S. Seitz U. Zacharias J.A. Schenk H. Schulz N. Huebner B. Micheel P.M. Schlag K.J. Osterziel C. Ozcelik S. Scherneck B. Jandrig 01. Dezember 2013 / Neuro Oncol Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis C. Hagemann S. Fuchs C.M. Monoranu P. Herrmann J. Smith T. Hohmann U. Grabiec A.F. Kessler F. Dehghani M. Loehr R.I. Ernestus G.H. Vince U. Stein 01. August 2017 / Ann Oncol Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies U.P. Rohr P. Herrmann K. Ilm H. Zhang S. Lohmann A. Reiser A. Muranyi J. Smith S. Burock M. Osterland K. Leith S. Singh P. Brunhoeber R. Bowermaster J. Tie M. Christie H.L. Wong P. Waring K. Shanmugam P. Gibbs U. Stein 01. Juni 2017 / PLoS Biol Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1 M. Juneja D. Kobelt W. Walther C. Voss J. Smith E. Specker M. Neuenschwander B.O. Gohlke M. Dahlmann S. Radetzki R. Preissner J.P. von Kries P.M. Schlag U. 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30. Mai 2014 / Oncotarget RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis M. Dahlmann A. Okhrimenko P. Marcinkowski M. Osterland P. Herrmann J. Smith C.W. Heizmann P.M. Schlag U. Stein
26. August 2021 / Oncogene The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis D. Kobelt D. Perez-Hernandez C. Fleuter M. Dahlmann F. Zincke J. Smith R. Migotti O. Popp S. Burock W. Walther G. Dittmar P. Mertins U. Stein
01. August 2009 / Cell Cycle MACC1 controls Met: What a difference an Sp1 site makes U. Stein J. Smith W. Walther F. Arlt
01. Februar 2011 / Neoplasia Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis U. Stein F. Arlt J. Smith U. Sack P. Herrmann W. Walther M. Lemm I. Fichtner R.H. Shoemaker P.M. Schlag
01. November 2006 / Gastroenterology The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer U. Stein F. Arlt W. Walther J. Smith T. Waldman E.D. Harris S.D. Mertins C.W. Heizmann D. Allard W. Birchmeier P.M. Schlag R.H. Shoemaker
01. Januar 2009 / Nat Med MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis U. Stein W. Walther F. Arlt H. Schwabe J. Smith I. Fichtner W. Birchmeier P.M. Schlag
01. Mai 2007 / Biol Chem Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway K. Wenzel K. Daskalow F. Herse S. Seitz U. Zacharias J.A. Schenk H. Schulz N. Huebner B. Micheel P.M. Schlag K.J. Osterziel C. Ozcelik S. Scherneck B. Jandrig
01. Dezember 2013 / Neuro Oncol Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis C. Hagemann S. Fuchs C.M. Monoranu P. Herrmann J. Smith T. Hohmann U. Grabiec A.F. Kessler F. Dehghani M. Loehr R.I. Ernestus G.H. Vince U. Stein
01. August 2017 / Ann Oncol Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies U.P. Rohr P. Herrmann K. Ilm H. Zhang S. Lohmann A. Reiser A. Muranyi J. Smith S. Burock M. Osterland K. Leith S. Singh P. Brunhoeber R. Bowermaster J. Tie M. Christie H.L. Wong P. Waring K. Shanmugam P. Gibbs U. Stein
01. Juni 2017 / PLoS Biol Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1 M. Juneja D. Kobelt W. Walther C. Voss J. Smith E. Specker M. Neuenschwander B.O. Gohlke M. Dahlmann S. Radetzki R. Preissner J.P. von Kries P.M. Schlag U. Stein