Veröffentlichungen | Max Delbrück Center

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30. August 2018 / Blood

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice

D. Hoser
C. Schön
C. Loddenkemper
P. Lohneis
A.A. Kühl
T. Sommermann
T. Blankenstein
G. Willimsky

01. August 2018 / Clin Cancer Res

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus

I. Gavvovidis
M. Leisegang
G. Willimsky
N.J. Miller
P. Nghiem
T. Blankenstein

01. August 2018 / Mol Ther

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma

J. Bluhm
E. Kieback
S.F. Marino
F. Oden
J. Westermann
M. Chmielewski
H. Abken
W. Uckert
U.E. Höpken
A. Rehm

01. Juni 2018 / Cancer Res

ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice

K. Schmidt
C. Keller
A.A. Kühl
A. Textor
U. Seifert
T. Blankenstein
G. Willimsky
P.M. Kloetzel

01. Januar 2018 / Cancer Immunol Res

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo

M. Szyska
S. Herda
S. Althoff
A. Heimann
J. Russ
D. D'Abundo
T.M. Dang
I. Durieux
B. Dörken
T. Blankenstein
I.K. Na

15. April 2015 / Int J Cancer

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB

A. Flörcken
M. Grau
A. Wolf
A. Weilemann
J. Kopp
B. Dörken
T. Blankenstein
A. Pezzutto
P. Lenz
G. Lenz
J. Westermann

01. April 2015 / Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

T. Blankenstein
M. Leisegang
W. Uckert
H. Schreiber

01. April 2015 / Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

M. Obenaus
C. Leitão
M. Leisegang
X. Chen
I. Gavvovidis
P. van der Bruggen
W. Uckert
D.J. Schendel
T. Blankenstein

23. März 2015 / PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

F.K.M. Lorenz
S. Wilde
K. Voigt
E. Kieback
B. Mosetter
D.J. Schendel
W. Uckert

01. Dezember 2000 / Gene Ther

Expression of B7.1 (CD80) in a renal cell carcinoma line allows expansion of tumor-associated cytotoxic T lymphocytes in the presence of an alloresponse

D.J. Schendel
B. Frankenberger
P. Jantzer
S. Cayeux
E. Noessner
G. Willimsky
B. Maget
H. Pohla
T. Blankenstein