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/ Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
/ Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
/ PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

  • F.K.M. Lorenz
  • S. Wilde
  • K. Voigt
  • E. Kieback
  • B. Mosetter
  • D.J. Schendel
  • W. Uckert
/ Eur J Immunol

Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells

  • S. Pinto
  • D. Sommermeyer
  • C. Michel
  • S. Wilde
  • D. Schendel
  • W. Uckert
  • T. Blankenstein
  • B. Kyewski
/ Proc Natl Acad Sci U S A

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

  • E. Kieback
  • J. Charo
  • D. Sommermeyer
  • T. Blankenstein
  • W. Uckert
/ Hum Gene Ther

Efficient gene transfer into primary human CD8+ T lymphocytes by MuLV-10A1 retrovirus pseudotype

  • W. Uckert
  • C. Becker
  • M. Gladow
  • D. Klein
  • T. Kammertoens
  • L. Pedersen
  • T. Blankenstein
/ J Gene Med

MLV-10A1 retrovirus pseudotype efficiently transduces primary human CD4+ T lymphocytes

  • M. Gladow
  • C. Becker
  • T. Blankenstein
  • W. Uckert