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in Blood

Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1

  • S. Reinke
  • P.J. Bröckelmann
  • I. Iaccarino
  • M. Garcia-Marquez
  • S. Borchmann
  • F. Jochims
  • M. Kotrova
  • K. Pal
  • M. Brüggemann
  • E. Hartmann
  • S. Sasse
  • C. Kobe
  • S. Mathas
  • M. Soekler
  • U. Keller
  • M. Bormann
  • A. Zimmermann
  • J. Richter
  • M. Fuchs
  • B. von Tresckow
  • P. Borchmann
  • H. Schlößer
  • M. von Bergwelt-Baildon
  • A. Rosenwald
  • A. Engert
  • W. Klapper
in JAMA Oncol

Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial

  • P.J. Bröckelmann
  • H. Goergen
  • U. Keller
  • J. Meissner
  • R. Ordemann
  • T.V. Halbsguth
  • S. Sasse
  • M. Sökler
  • A. Kerkhoff
  • S. Mathas
  • A. Hüttmann
  • M. Bormann
  • A. Zimmermann
  • J. Mettler
  • M. Fuchs
  • B. von Tresckow
  • C. Baues
  • A. Rosenwald
  • W. Klapper
  • C. Kobe
  • P. Borchmann
  • A. Engert
in Blood

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma

  • J.I. Martin-Subero
  • I. Wlodarska
  • C. Bastard
  • J.M. Picquenot
  • J. Hoeppner
  • M. Giefing
  • W. Klapper
  • R. Siebert
  • S. Mathas
  • S. Joos
  • H. Stein
  • B. Doerken
in Cell Cycle

Reprogramming of B lymphoid cells in human lymphoma pathogenesis

  • M. Janz
  • B. Doerken
  • S. Mathas
in Blood

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells

  • M. Janz
  • M. Hummel
  • M. Truss
  • B. Wollert-Wulf
  • S. Mathas
  • K. Joehrens
  • C. Hagemeier
  • K. Bommert
  • H. Stein
  • B. Doerken
  • R.C. Bargou
in Nat Immunol

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

  • S. Mathas
  • M. Janz
  • F. Hummel
  • M. Hummel
  • B. Wollert-Wulf
  • S. Lusatis
  • I. Anagnostopoulos
  • A. Lietz
  • M. Sigvardsson
  • F. Jundt
  • K. Joehrens
  • K. Bommert
  • H. Stein
  • B. Doerken
in J Exp Med

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

  • S. Mathas
  • A. Lietz
  • I. Anagnostopoulos
  • F. Hummel
  • B. Wiesner
  • M. Janz
  • F. Jundt
  • B. Hirsch
  • K. Joehrens-Leder
  • H.P. Vornlocher
  • K. Bommert
  • H. Stein
  • B. Doerken
in Blood

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells

  • F. Jundt
  • K. Schulze-Proebsting
  • I. Anagnostopoulos
  • G. Muehlinghaus
  • M. Chatterjee
  • S. Mathas
  • R.C. Bargou
  • R. Manz
  • H. Stein
  • B. Doerken
in Blood

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp 130/STAT3 pathway

  • M. Chatterjee
  • D. Hoenemann
  • S. Lentzsch
  • K. Bommert
  • C. Sers
  • P. Herrmann
  • S. Mathas
  • B. Doerken
  • R.C. Bargou
in J Exp Med

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

  • M. Hinz
  • P. Lemke
  • I. Anagnostopoulos
  • C. Hacker
  • D. Krappmann
  • S. Mathas
  • B. Doerken
  • M. Zenke
  • H. Stein
  • C. Scheidereit