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02. Januar 2019 in J Clin Invest

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression

L. Poncette
X. Chen
F.K.M. Lorenz
T. Blankenstein

08. November 2016 in eLife

Domain-swapped T cell receptors improve the safety of TCR gene therapy

M.T. Bethune
M.H. Gee
M. Bunse
M.S. Lee
E.H. Gschweng
M.S. Pagadala
J. Zhou
D. Cheng
J.R. Heath
D.B. Kohn
M.S. Kuhns
W. Uckert
D. Baltimore

03. November 2016 in Blood

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors

M. Richter
K. Saydaminova
R. Yumul
R. Krishnan
J. Liu
E.E. Nagy
M. Singh
Z. Izsvák
R. Cattaneo
W. Uckert
D. Palmer
P. Ng
K.G. Haworth
H.P. Kiem
A. Ehrhardt
T. Papayannopoulou
A. Lieber

01. August 2016 in Mol Cancer Ther

ERK1 as a therapeutic target for dendritic cell vaccination against high-grade gliomas

M.C. Ku
I. Edes
I. Bendix
A. Pohlmann
H. Waiczies
T. Prozorovski
M. Günther
C. Martin
G. Pagès
S.A. Wolf
H. Kettenmann
W. Uckert
T. Niendorf
S. Waiczies

01. Juni 2016 in Clin Cancer Res

Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation

M. Leisegang
B. Engels
K. Schreiber
P.Y. Yew
K. Kiyotani
C. Idel
A. Arina
J. Duraiswamy
R.R. Weichselbaum
W. Uckert
Y. Nakamura
H. Schreiber

17. Mai 2016 in Immunity

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity

E. Kieback
E. Hilgenberg
U. Stervbo
V. Lampropoulou
P. Shen
M. Bunse
Y. Jaimes
P. Boudinot
A. Radbruch
U. Klemm
A.A. Kühl
R. Liblau
N. Hoevelmeyer
S.M. Anderton
W. Uckert
S. Fillatreau

25. April 2016 in Oncoimmunology

Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity

D. Schirmer
T.G.P. Grünewald
R. Klar
O. Schmidt
D. Wohlleber
R.A. Rubio
W. Uckert
U. Thiel
F. Bohne
D.H. Busch
A.M. Krackhardt
S. Burdach
G.H.S. Richter

06. April 2016 in Sci Rep

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes

F. Ebstein
K. Textoris-Taube
C. Keller
R. Golnik
N. Vigneron
B.J. Van den Eynde
B. Schuler-Thurner
D. Schadendorf
F.K.M. Lorenz
W. Uckert
S. Urban
A. Lehmann
N. Albrecht-Koepke
K. Janek
P. Henklein
A. Niewienda
P.M. Kloetzel
M. Mishto

01. März 2016 in Mol Ther

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells

A. Gogol-Döring
I. Ammar
S. Gupta
M. Bunse
C. Miskey
W. Chen
W. Uckert
T.F. Schulz
Z. Izsvák
Z. Ivics

01. März 2016 in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

M. Leisegang
T. Kammertoens
W. Uckert
T. Blankenstein