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in Gastroenterology

T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice

  • C. Dargel
  • M. Bassani-Sternberg
  • J. Hasreiter
  • F. Zani
  • J.H. Bockmann
  • F. Thiele
  • F. Bohne
  • K. Wisskirchen
  • S. Wilde
  • M.F. Sprinzl
  • D.J. Schendel
  • A.M. Krackhardt
  • W. Uckert
  • D. Wohlleber
  • M. Schiemann
  • K. Stemmer
  • M. Heikenwälder
  • D.H. Busch
  • G. Richter
  • M. Mann
  • U. Protzer
in BIOspektrum

Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs]

  • M. Leisegang
  • W. Uckert
in Int J Cancer

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB

  • A. Flörcken
  • M. Grau
  • A. Wolf
  • A. Weilemann
  • J. Kopp
  • B. Dörken
  • T. Blankenstein
  • A. Pezzutto
  • P. Lenz
  • G. Lenz
  • J. Westermann
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
in PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

  • F.K.M. Lorenz
  • S. Wilde
  • K. Voigt
  • E. Kieback
  • B. Mosetter
  • D.J. Schendel
  • W. Uckert
in J Clin Invest

MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4

  • J.T. Walsh
  • S. Hendrix
  • F. Boato
  • I. Smirnov
  • J. Zheng
  • J.R. Lukens
  • S. Gadani
  • D. Hechler
  • G. Gölz
  • K. Rosenberger
  • T. Kammertöns
  • J. Vogt
  • C. Vogelaar
  • V. Siffrin
  • A. Radjavi
  • A. Fernandez-Castaneda
  • A. Gaultier
  • R. Gold
  • T.D. Kanneganti
  • R. Nitsch
  • F. Zipp
  • J. Kipnis
in J Immunol

CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor

  • S. Ghorashian
  • P. Veliça
  • I. Chua
  • A. McNicol
  • B. Carpenter
  • A. Holler
  • E. Nicholson
  • M. Ahmadi
  • M. Zech
  • S. Xue
  • W. Uckert
  • E. Morris
  • R. Chakraverty
  • H.J. Stauss
in J Immunol

IFN-γ regulates CD8(+) memory T cell differentiation and survival in response to weak, but not strong, TCR signals

  • D. Stoycheva
  • K. Deiser
  • L. Stärck
  • G. Nishanth
  • D. Schlüter
  • W. Uckert
  • T. Schüler
in Canc Cell

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer

  • K. Anders
  • C. Buschow
  • A. Herrmann
  • A. Milojkovic
  • C. Loddenkemper
  • T. Kammertoens
  • P. Daniel
  • H. Yu
  • J. Charo
  • T. Blankenstein