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in J Clin Invest

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression

  • L. Poncette
  • X. Chen
  • F.K.M. Lorenz
  • T. Blankenstein
in Canc Res

Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy

  • R. Schlenker
  • L.F. Olguín-Contreras
  • M. Leisegang
  • J. Schnappinger
  • A. Disovic
  • S. Rühland
  • P.J. Nelson
  • H. Leonhardt
  • H. Harz
  • S. Wilde
  • D.J. Schendel
  • W. Uckert
  • G. Willimsky
  • E. Noessner
in Nature

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

  • T. Kammertoens
  • C. Friese
  • A. Arina
  • C. Idel
  • D. Briesemeister
  • M. Rothe
  • A. Ivanov
  • A. Szymborska
  • G. Patone
  • S. Kunz
  • D. Sommermeyer
  • B. Engels
  • M. Leisegang
  • A. Textor
  • H.J. Fehling
  • M. Fruttiger
  • M. Lohoff
  • A. Herrmann
  • H. Yu
  • R. Weichselbaum
  • W. Uckert
  • N. Hübner
  • H. Gerhardt
  • D. Beule
  • H. Schreiber
  • T. Blankenstein
in Mol Cell Biol

Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element

  • A.S. Schultz
  • M. Preussner
  • M. Bunse
  • R. Karni
  • F. Heyd
in BIOspektrum

Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs]

  • M. Leisegang
  • W. Uckert
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
in Hum Gene Ther Clin Dev

HEK293-based production platform for γ-retroviral (SIN-) vectors: application for safe and efficient transfer of COL7A1 cDNA

  • K. Hennig
  • L. Raasch
  • C. Kolbe
  • S. Weidner
  • M. Leisegang
  • W. Uckert
  • M. Titeux
  • A. Hovnanian
  • K. Kuehlcke
  • R. Loew
in Mol Ther

RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer

  • M. Bunse
  • G.M. Bendle
  • C. Linnemann
  • L. Bies
  • S. Schulz
  • T.N. Schumacher
  • W. Uckert
in Eur J Immunol

Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells

  • S. Pinto
  • D. Sommermeyer
  • C. Michel
  • S. Wilde
  • D. Schendel
  • W. Uckert
  • T. Blankenstein
  • B. Kyewski