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in Gastroenterology

T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice

  • C. Dargel
  • M. Bassani-Sternberg
  • J. Hasreiter
  • F. Zani
  • J.H. Bockmann
  • F. Thiele
  • F. Bohne
  • K. Wisskirchen
  • S. Wilde
  • M.F. Sprinzl
  • D.J. Schendel
  • A.M. Krackhardt
  • W. Uckert
  • D. Wohlleber
  • M. Schiemann
  • K. Stemmer
  • M. Heikenwälder
  • D.H. Busch
  • G. Richter
  • M. Mann
  • U. Protzer
in BIOspektrum

Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs]

  • M. Leisegang
  • W. Uckert
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein
in PLoS ONE

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7

  • F.K.M. Lorenz
  • S. Wilde
  • K. Voigt
  • E. Kieback
  • B. Mosetter
  • D.J. Schendel
  • W. Uckert
in J Immunol

CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor

  • S. Ghorashian
  • P. Veliça
  • I. Chua
  • A. McNicol
  • B. Carpenter
  • A. Holler
  • E. Nicholson
  • M. Ahmadi
  • M. Zech
  • S. Xue
  • W. Uckert
  • E. Morris
  • R. Chakraverty
  • H.J. Stauss
in J Immunol

IFN-γ regulates CD8(+) memory T cell differentiation and survival in response to weak, but not strong, TCR signals

  • D. Stoycheva
  • K. Deiser
  • L. Stärck
  • G. Nishanth
  • D. Schlüter
  • W. Uckert
  • T. Schüler
in Blood

T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing

  • Q. Zhou
  • I.C. Schneider
  • I. Edes
  • A. Honegger
  • P. Bach
  • K. Schoenfeld
  • A. Schambach
  • W.S. Wels
  • S. Kneissl
  • W. Uckert
  • C.J. Buchholz
in J Virol

Protective capacity of virus-specific T cell receptor (TCR)-transduced CD8 T cells in vivo

  • K. Mueller
  • A. von Maessenhausen
  • U. Aichele
  • L. Staerck
  • M. Leisegang
  • W. Uckert
  • H. Pircher
in J Immunol

Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition

  • S. Wilde
  • D. Sommermeyer
  • M. Leisegang
  • B. Frankenberger
  • B. Mosetter
  • W. Uckert
  • D.J. Schendel