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01. Januar 2021 in Life Sci Allianc

Myeloid transformation by MLL-ENL depends strictly on C/EBP

R. Wesolowski
E. Kowenz-Leutz
K. Zimmermann
D. Dörr
M. Hofstätter
R.K. Slany
A. Mildner
A. Leutz

15. Dezember 2020 in ACS Omega

The role of orthosteric building blocks of bitopic ligands for muscarinic M1 receptors

D. Volpato
M. Kauk
R. Messerer
M. Bermudez
G. Wolber
A. Bock
C. Hoffmann
U. Holzgrabe

09. Oktober 2020 in ACS Pharmacol Transl Sci

Ligand-specific allosteric coupling controls G-protein-coupled receptor signaling

J. Holze
M. Bermudez
E.M. Pfeil
M. Kauk
T. Bödefeld
M. Irmen
C. Matera
C. Dallanoce
M. De Amici
U. Holzgrabe
G.M. König
C. Tränkle
G. Wolber
R. Schrage
K. Mohr
C. Hoffmann
E. Kostenis
A. Bock

17. September 2020 in Cell

Optical mapping of cAMP signaling at the nanometer scale

A. Bock
P. Annibale
C. Konrad
A. Hannawacker
S.E. Anton
I. Maiellaro
U. Zabel
S. Sivaramakrishnan
M. Falcke
M.J. Lohse

01. September 2020 in Nat Chem Biol

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors

J. Möller
A. Isbilir
T. Sungkaworn
B. Osberg
C. Karathanasis
V. Sunkara
E.O. Grushevskyi
A. Bock
P. Annibale
M. Heilemann
C. Schütte
M.J. Lohse

21. Juni 2019 in ACS Chem Biol

Quantitative single-residue bioorthogonal labeling of G protein-coupled receptors in live cells

R. Serfling
L. Seidel
A. Bock
M.J. Lohse
P. Annibale
I. Coin

14. Mai 2019 in Proc Natl Acad Sci U S A

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement

E.O. Grushevskyi
T. Kukaj
R. Schmauder
A. Bock
U. Zabel
T. Schwabe
K. Benndorf
M.J. Lohse

01. April 2019 in Trends Pharmacol Sci

Does divergent binding pocket closure drive ligand bias for class A GPCRs?

M. Bermudez
A. Bock

29. März 2019 in iScience

PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb

G. Dittmar
D. Perez Hernandez
E. Kowenz-Leutz
M. Kirchner
G. Kahlert
R. Wesolowski
K. Baum
M. Knoblich
M. Hofstätter
A. Muller
J. Wolf
U. Reimer
A. Leutz

01. Juli 2018 in Neuropharmacology

Allosteric modulators targeting CNS muscarinic receptors

A. Bock
R. Schrage
K. Mohr