Woman reading in MDC library

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in Nucleic Acids Res

A single amino acid switch converts the sleeping beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming

L. Kesselring et al.
in Sci Transl Med

The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

S.E. Murthy et al.
in Mol Ther Nucleic Acids

The antibiotic-free pFAR4 vector paired with the sleeping beauty transposon sSystem mediates efficient transgene delivery in human cells

M. Pastor et al.
in Genes Dev

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

M. Kim et al.
in Hum Gene Ther

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR

J. Clauss et al.
in Mol Ther

Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle Sleeping Beauty transposon vectors

M. Holstein et al.
in Neuron

Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability

J.M. Dawes et al.
in Mol Ther Nucleic Acids

Long-term PEDF release in rat iris and retinal epithelial cells after Sleeping Beauty transposon-mediated gene delivery

L. Garcia-Garcia et al.
in Trends Genet

Gene therapy with the Sleeping Beauty transposon system

P. Kebriaei et al.
in Nature

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics

U. Elling et al.