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in Immunity

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity

  • E. Kieback
  • E. Hilgenberg
  • U. Stervbo
  • V. Lampropoulou
  • P. Shen
  • M. Bunse
  • Y. Jaimes
  • P. Boudinot
  • A. Radbruch
  • U. Klemm
  • A.A. Kühl
  • R. Liblau
  • N. Hoevelmeyer
  • S.M. Anderton
  • W. Uckert
  • S. Fillatreau
in Mol Ther

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells

  • A. Gogol-Döring
  • I. Ammar
  • S. Gupta
  • M. Bunse
  • C. Miskey
  • W. Chen
  • W. Uckert
  • T.F. Schulz
  • Z. Izsvák
  • Z. Ivics
in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

  • M. Leisegang
  • T. Kammertoens
  • W. Uckert
  • T. Blankenstein
in Genome Res

Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice

  • M. Spielmann
  • N. Kakar
  • N. Tayebi
  • C. Leettola
  • G. Nürnberg
  • N. Sowada
  • D.G. Lupiáñez
  • I. Harabula
  • R. Flöttmann
  • D. Horn
  • W.L. Chan
  • L. Wittler
  • R. Yilmaz
  • J. Altmüller
  • H. Thiele
  • H. van Bokhoven
  • C.E. Schwartz
  • P. Nürnberg
  • J.U. Bowie
  • J. Ahmad
  • C. Kubisch
  • S. Mundlos
  • G. Borck
in Hum Genet

Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3

  • B.S. Budde
  • S. Mizumoto
  • R. Kogawa
  • C. Becker
  • J. Altmüller
  • H. Thiele
  • F. Rueschendorf
  • M.R. Toliat
  • G. Kaleschke
  • J.M. Haemmerle
  • W. Hoehne
  • K. Sugahara
  • P. Nuernberg
  • I. Kennerknecht
in Ann Neurol

Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes

  • E.M. Reinthaler
  • B. Dejanovic
  • D. Lal
  • M. Semtner
  • Y. Merkler
  • A. Reinhold
  • D.A. Pittrich
  • C. Hotzy
  • M. Feucht
  • H. Steinboeck
  • U. Gruber-Sedlmayr
  • G. Ronen
  • B. Neophytou
  • J. Geldner
  • E. Haberlandt
  • H. Muhle
  • M.A. Ikram
  • CM. van Duijn
  • A.G. Uitterlinden
  • A. Hofman
  • J. Altmüller
  • A. Kawalia
  • M.R. Toliat
  • P. Nuernberg
  • H. Lerche
  • M. Nothnagel
  • H. Thiele
  • T. Sander
  • J.C. Meier
  • G. Schwarz
  • B.A. Neubauer
  • F. Zimprich
in Curr Opin Immunol

Targeting cancer-specific mutations by T cell receptor gene therapy

  • T. Blankenstein
  • M. Leisegang
  • W. Uckert
  • H. Schreiber
in Nat Biotechnol

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

  • M. Obenaus
  • C. Leitão
  • M. Leisegang
  • X. Chen
  • I. Gavvovidis
  • P. van der Bruggen
  • W. Uckert
  • D.J. Schendel
  • T. Blankenstein