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in Proc Natl Acad Sci U S A

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

  • V.T. Chu
  • R. Graf
  • T. Wirtz
  • T. Weber
  • J. Favret
  • X. Li
  • K. Petsch
  • N.T. Tran
  • M.H. Sieweke
  • C. Berek
  • R. Kühn
  • K. Rajewsky
in Immunity

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity

  • E. Kieback
  • E. Hilgenberg
  • U. Stervbo
  • V. Lampropoulou
  • P. Shen
  • M. Bunse
  • Y. Jaimes
  • P. Boudinot
  • A. Radbruch
  • U. Klemm
  • A.A. Kühl
  • R. Liblau
  • N. Hoevelmeyer
  • S.M. Anderton
  • W. Uckert
  • S. Fillatreau
in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

  • M. Leisegang
  • T. Kammertoens
  • W. Uckert
  • T. Blankenstein
in Clin Cancer Res

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy

  • M. Leisegang
  • A. Turqueti-Neves
  • B. Engels
  • T. Blankenstein
  • D.J. Schendel
  • W. Uckert
  • E. Noessner
in Hum Gene Ther

Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma

  • A. Buchner
  • H. Pohla
  • G. Willimsky
  • B. Frankenberger
  • R. Frank
  • A. Baur-Melnyk
  • M. Siebels
  • C.G. Stief
  • A. Hofstetter
  • J. Kopp
  • A. Pezzutto
  • T. Blankenstein
  • R. Oberneder
  • D.J. Schendel