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in Proc Natl Acad Sci U S A

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

  • V.T. Chu
  • R. Graf
  • T. Wirtz
  • T. Weber
  • J. Favret
  • X. Li
  • K. Petsch
  • N.T. Tran
  • M.H. Sieweke
  • C. Berek
  • R. Kühn
  • K. Rajewsky
in Proc Natl Acad Sci U S A

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells

  • E. Derudder
  • S. Herzog
  • V. Labi
  • T. Yasuda
  • K. Köchert
  • M. Janz
  • A. Villunger
  • M. Schmidt-Supprian
  • K. Rajewsky
in Genome Med

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses

  • K.A.P. de Oliveira
  • E. Kaergel
  • M. Heinig
  • J.F. Fontaine
  • G. Patone
  • E.M. Muro
  • S. Mathas
  • M. Hummel
  • M.A. Andrade-Navarro
  • N. Hübner
  • C. Scheidereit
in Nature

FOXO1 couples metabolic activity and growth state in the vascular endothelium

  • K. Wilhelm
  • K. Happel
  • G. Eelen
  • S. Schoors
  • M.F. Oellerich
  • R. Lim
  • B. Zimmermann
  • I.M. Aspalter
  • C.A. Franco
  • T. Boettger
  • T. Braun
  • M. Fruttiger
  • K. Rajewsky
  • C. Keller
  • J.C. Brüning
  • H. Gerhardt
  • P. Carmeliet
  • M. Potente
in Nat Immunol

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

  • D.P. Calado
  • Y. Sasaki
  • S.A. Godinho
  • A. Pellerin
  • K. Köchert
  • B.P. Sleckman
  • I.M. de Alboran
  • M. Janz
  • S. Rodig
  • K. Rajewsky
in Br J Dermatol

The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome

  • B. Lamprecht
  • S. Kreher
  • M. Moebs
  • W. Sterry
  • B. Doerken
  • M. Janz
  • C. Assaf
  • S. Mathas