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in Immunity

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity

  • E. Kieback
  • E. Hilgenberg
  • U. Stervbo
  • V. Lampropoulou
  • P. Shen
  • M. Bunse
  • Y. Jaimes
  • P. Boudinot
  • A. Radbruch
  • U. Klemm
  • A.A. Kühl
  • R. Liblau
  • N. Hoevelmeyer
  • S.M. Anderton
  • W. Uckert
  • S. Fillatreau
in Mol Ther

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells

  • A. Gogol-Döring
  • I. Ammar
  • S. Gupta
  • M. Bunse
  • C. Miskey
  • W. Chen
  • W. Uckert
  • T.F. Schulz
  • Z. Izsvák
  • Z. Ivics
in J Clin Invest

Targeting human melanoma neoantigens by T cell receptor gene therapy

  • M. Leisegang
  • T. Kammertoens
  • W. Uckert
  • T. Blankenstein
in Clin Cancer Res

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy

  • M. Leisegang
  • A. Turqueti-Neves
  • B. Engels
  • T. Blankenstein
  • D.J. Schendel
  • W. Uckert
  • E. Noessner
in Proc Natl Acad Sci U S A

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

  • E. Kieback
  • J. Charo
  • D. Sommermeyer
  • T. Blankenstein
  • W. Uckert
in Gene Ther

In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine

  • S. Cayeux
  • B. Bukarica
  • C. Buschow
  • J. Charo
  • M. Bunse
  • B. Doerken
  • T. Blankenstein