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in Mol Ther

CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat Severe Congenital Neutropenia

  • N.T. Tran
  • R. Graf
  • A. Wulf-Goldenberg
  • M. Stecklum
  • G. Strauß
  • R. Kühn
  • C. Kocks
  • K. Rajewsky
  • V.T. Chu
in Front Immunol

B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS

  • K. Schmidt
  • U. Sack
  • R. Graf
  • W. Winkler
  • O. Popp
  • P. Mertins
  • T. Sommermann
  • C. Kocks
  • K. Rajewsky
in Cell Rep

Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells

  • N.T. Tran
  • T. Sommermann
  • R. Graf
  • J. Trombke
  • J. Pempe
  • K. Petsch
  • R. Kühn
  • K. Rajewsky
  • V.T. Chu
in Front Genet

Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells

  • T.T.H. Le
  • N.T. Tran
  • T.M.L. Dao
  • D.D. Nguyen
  • H.D. Do
  • T.L. Ha
  • R. Kühn
  • T.L. Nguyen
  • K. Rajewsky
  • V.T. Chu
in Front Genet

Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors

  • N.T. Tran
  • S. Bashir
  • X. Li
  • J. Rossius
  • V.T. Chu
  • K. Rajewsky
  • R. Kühn
in Acta Neuropathol Commun

Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

  • V. Haage
  • M. Semtner
  • R. Oliveira Vidal
  • D. Perez Hernandez
  • W.W. Pong
  • Z. Chen
  • D. Hambardzumyan
  • V. Magrini
  • A. Ly
  • J. Walker
  • E. Mardis
  • P. Mertins
  • S. Sauer
  • H. Kettenmann
  • D.H. Gutmann
in Eur J Immunol

A novel allele for inducible Cre expression in germinal center B cells

  • T. Weber
  • J. Seagal
  • W. Winkler
  • T. Wirtz
  • V.T. Chu
  • K. Rajewsky
in Cell Stem Cell

Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders

  • C. Lorenz
  • P. Lesimple
  • R. Bukowiecki
  • A. Zink
  • G. Inak
  • B. Mlody
  • M. Singh
  • M. Semtner
  • N. Mah
  • K. Auré
  • M. Leong
  • O. Zabiegalov
  • E.M. Lyras
  • V. Pfiffer
  • B. Fauler
  • J. Eichhorst
  • B. Wiesner
  • N. Huebner
  • J. Priller
  • T. Mielke
  • D. Meierhofer
  • Z. Izsvák
  • J.C. Meier
  • F. Bouillaud
  • J. Adjaye
  • M. Schuelke
  • E.E. Wanker
  • A. Lombès
  • A. Prigione
in Proc Natl Acad Sci U S A

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

  • V.T. Chu
  • R. Graf
  • T. Wirtz
  • T. Weber
  • J. Favret
  • X. Li
  • K. Petsch
  • N.T. Tran
  • M.H. Sieweke
  • C. Berek
  • R. Kühn
  • K. Rajewsky
in Cereb Cortex

Identification of parvalbumin interneurons as cellular substrate of fear memory persistence

  • G. Caliskan
  • I. Mueller
  • M. Semtner
  • A. Winkelmann
  • A.S. Raza
  • J.O. Hollnagel
  • A. Roesler
  • U. Heinemann
  • O. Stork
  • J.C. Meier