Veröffentlichungen | MDC Berlin

12 Ergebnisse:

Active Filter:

03. Juni 2022 in Sci Adv

Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells

N.T. Tran
E. Danner
X. Li
R. Graf
M. Lebedin
K. de la Rosa
R. Kühn
K. Rajewsky
V.T. Chu

28. Dezember 2021 in Cell Rep

Microglia sense neuronal activity via GABA in the early postnatal hippocampus

F. Logiacco
P. Xia
S.V. Georgiev
C. Franconi
Y.J. Chang
B. Ugursu
A. Sporbert
R. Kühn
H. Kettenmann
M. Semtner

02. Dezember 2020 in Mol Ther

CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia

N.T. Tran
R. Graf
A. Wulf-Goldenberg
M. Stecklum
G. Strauß
R. Kühn
C. Kocks
K. Rajewsky
V.T. Chu

24. September 2019 in Cell Rep

Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells

N.T. Tran
T. Sommermann
R. Graf
J. Trombke
J. Pempe
K. Petsch
R. Kühn
K. Rajewsky
V.T. Chu

01. Juli 2019 in Front Genet

Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells

T.T.H. Le
N.T. Tran
T.M.L. Dao
D.D. Nguyen
H.D. Do
T.L. Ha
R. Kühn
T.L. Nguyen
K. Rajewsky
V.T. Chu

30. April 2019 in Front Genet

Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors

N.T. Tran
S. Bashir
X. Li
J. Rossius
V.T. Chu
K. Rajewsky
R. Kühn

01. Januar 2019 in Eur J Immunol

A novel allele for inducible Cre expression in germinal center B cells

T. Weber
J. Seagal
W. Winkler
T. Wirtz
V.T. Chu
K. Rajewsky

01. November 2016 in Proc Natl Acad Sci U S A

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

V.T. Chu
R. Graf
T. Wirtz
T. Weber
J. Favret
X. Li
K. Petsch
N.T. Tran
M.H. Sieweke
C. Berek
R. Kühn
K. Rajewsky

16. Januar 2016 in BMC Biotechnol

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

V.T. Chu
T. Weber
R. Graf
T. Sommermann
K. Petsch
U. Sack
P. Volchkov
K. Rajewsky
R. Kühn

10. November 2015 in Genome Biol

Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9

R. Kühn
V.T. Chu