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SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma

G.J.J.E. Heynen
F. Baumgartner
M. Heider
U. Patra
M. Holz
J. Braune
M. Kaiser
I. Schäffer
S.A. Bamopoulos
E. Ramberger
A. Murgai
Y.L.D. Ng
U.M. Demel
D. Laue
S. Liebig
J. Krüger
M. Janz
A. Nogai
M. Schick
P. Mertins
S. Müller
F. Bassermann
J. Krönke
U. Keller
M. Wirth

Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma

A.S. Jacob
H. Kaul
M. Fuchs
S. Gillessen
S. Kreissl
A. Pluetschow
J. Momotow
V. Schaub
A. Huettmann
M. Haenel
A. Zimmermann
J. Dierlamm
J. Meissner
S. Mathas
S. Martin
A. Engert
M. Hallek
P. Borchmann
C. Lehmann

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase in B cell lymphomas

C. Lopez
N. Schleussner
S.H. Bernhart
K. Kleinheinz
S. Sungalee
H.L. Sczakiel
H. Kretzmer
U.H. Toprak
S. Glaser
R. Wagener
O. Ammerpohl
S. Bens
M. Giefing
J.C.G. Sanchez
G. Apic
D. Hubschmann
M. Janz
M. Kreuz
A. Mottok
J.M. Müller
J. Seufert
S. Hoffmann
J.O. Korbel
R.B. Russell
R. Schule
L. Trumper
W. Klapper
B. Radlwimmer
P. Lichter
R. Kuppers
M. Schlesner
S. Mathas
R. Siebert

Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group

C. Damaschin
H. Goergen
S. Kreissl
A. Plütschow
F. Breywisch
S. Mathas
J. Meissner
M. Sökler
M.S. Topp
V. Vucinic
A. Zimmermann
B. von Tresckow
M. Fuchs
A. Engert
P. Borchmann
D.A. Eichenauer

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals

S. Denker
A. Bittner
M. Frick
J. Kase
J. Hoffmann
C. Trenker
U. Keller
C. Bogner
A. Hüttmann
J. Dürig
M. Janz
S. Mathas
R. Marks
U. Krohn
I.K. Na
L. Bullinger
C.A. Schmitt

Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL)

K.D. Wurster
M. Costanza
S. Kreher
S. Glaser
B. Lamprecht
N. Schleussner
I. Anagnostopoulos
M. Hummel
K. Jöhrens
H. Stein
A. Molina
A. Diepstra
B. Gillissen
K. Köchert
R. Siebert
O. Merkel
L. Kenner
M. Janz
S. Mathas

22. September 2021 in Nat Commun

Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma

H.C. Liang
M. Costanza
N. Prutsch
M.W. Zimmerman
E. Gurnhofer
I.A. Montes-Mojarro
B.J. Abraham
N. Prokoph
S. Stoiber
S. Tangermann
C. Lobello
J. Oppelt
I. Anagnostopoulos
T. Hielscher
S. Pervez
W. Klapper
F. Zammarchi
D.A. Silva
K.C. Garcia
D. Baker
M. Janz
N. Schleussner
F. Fend
Š. Pospíšilová
A. Janiková
J. Wallwitz
D. Stoiber
I. Simonitsch-Klupp
L. Cerroni
S. Pileri
L. de Leval
D. Sibon
V. Fataccioli
P. Gaulard
C. Assaf
F. Knörr
C. Damm-Welk
W. Woessmann
S.D. Turner
A.T. Look
S. Mathas
L. Kenner
O. Merkel

High-dose glucocorticoid treatment of near-fatal Bocavirus lung infection results in rapid recovery

M. Obenaus
O. Schildgen
D. Schürmann
A.C. von Brünneck
M. Janz
U. Keller
B. Gebauer
J. Schilling
S. Schwartz
B. Weissbrich
T. Schneider
J. Hofmann
S. Mathas

Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1

S. Reinke
P.J. Bröckelmann
I. Iaccarino
M. Garcia-Marquez
S. Borchmann
F. Jochims
M. Kotrova
K. Pal
M. Brüggemann
E. Hartmann
S. Sasse
C. Kobe
S. Mathas
M. Soekler
U. Keller
M. Bormann
A. Zimmermann
J. Richter
M. Fuchs
B. von Tresckow
P. Borchmann
H. Schlößer
M. von Bergwelt-Baildon
A. Rosenwald
A. Engert
W. Klapper

B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS

K. Schmidt
U. Sack
R. Graf
W. Winkler
O. Popp
P. Mertins
T. Sommermann
C. Kocks
K. Rajewsky