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15. März 2021 in EMBO J

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence

M. Kolesnichenko
N. Mikuda
U.E. Höpken
E. Kärgel
B. Uyar
A.B. Tufan
M. Milanovic
W. Sun
I. Krahn
K. Schleich
L. von Hoff
M. Hinz
M. Willenbrock
S. Jungmann
A. Akalin
S. Lee
R. Schmidt-Ullrich
C.A. Schmitt
C. Scheidereit

02. Dezember 2020 in Mol Ther

CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia

N.T. Tran
R. Graf
A. Wulf-Goldenberg
M. Stecklum
G. Strauß
R. Kühn
C. Kocks
K. Rajewsky
V.T. Chu

01. Dezember 2020 in Front Immunol

B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS

K. Schmidt
U. Sack
R. Graf
W. Winkler
O. Popp
P. Mertins
T. Sommermann
C. Kocks
K. Rajewsky

24. September 2019 in Cell Rep

Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells

N.T. Tran
T. Sommermann
R. Graf
J. Trombke
J. Pempe
K. Petsch
R. Kühn
K. Rajewsky
V.T. Chu

01. Juli 2019 in Front Genet

Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells

T.T.H. Le
N.T. Tran
T.M.L. Dao
D.D. Nguyen
H.D. Do
T.L. Ha
R. Kühn
T.L. Nguyen
K. Rajewsky
V.T. Chu

30. April 2019 in Front Genet

Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors

N.T. Tran
S. Bashir
X. Li
J. Rossius
V.T. Chu
K. Rajewsky
R. Kühn

01. Januar 2019 in Kidney Int

Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury

E. Vigolo
L. Markó
C. Hinze
D.N. Müller
R. Schmidt-Ullrich
K.M. Schmidt-Ott

14. Dezember 2018 in EMBO J

The IκB kinase complex is a regulator of mRNA stability

N. Mikuda
M. Kolesnichenko
P. Beaudette
O. Popp
B. Uyar
W. Sun
A.B. Tufan
B. Perder
A. Akalin
W. Chen
P. Mertins
G. Dittmar
M. Hinz
C. Scheidereit

20. September 2018 in Cell

Mutations in disordered regions can cause disease by creating dileucine motifs

K. Meyer
M. Kirchner
B. Uyar
J.Y. Cheng
G. Russo
L.R. Hernandez-Miranda
A. Szymborska
H. Zauber
I.M. Rudolph
T.E. Willnow
A. Akalin
V. Haucke
H. Gerhardt
C. Birchmeier
R. Kühn
M. Krauss
S. Diecke
J.M. Pascual
M. Selbach

01. September 2018 in Leukemia

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma

N. Schleussner
O. Merkel
M. Costanza
H.C. Liang
F. Hummel
C. Romagnani
P. Durek
I. Anagnostopoulos
M. Hummel
K. Jöhrens
A. Niedobitek
P.R. Griffin
R. Piva
H.L. Sczakiel
W. Woessmann
C. Damm-Welk
C. Hinze
D. Stoiber
B. Gillissen
S.D. Turner
E. Kaergel
L. von Hoff
M. Grau
G. Lenz
B. Dörken
C. Scheidereit
L. Kenner
M. Janz
S. Mathas