Veröffentlichungen | MDC Berlin

96 Ergebnisse:

Active Filter:

18. Januar 2021 in EMBO J

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence

M. Kolesnichenko
N. Mikuda
U.E. Höpken
E. Kärgel
B. Uyar
A.B. Tufan
M. Milanovic
W. Sun
I. Krahn
K. Schleich
L. von Hoff
M. Hinz
M. Willenbrock
S. Jungmann
A. Akalin
S. Lee
R. Schmidt-Ullrich
C.A. Schmitt
C. Scheidereit

02. Dezember 2020 in Mol Ther

CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat Severe Congenital Neutropenia

N.T. Tran
R. Graf
A. Wulf-Goldenberg
M. Stecklum
G. Strauß
R. Kühn
C. Kocks
K. Rajewsky
V.T. Chu

28. Juli 2020 in Front Physiol

A quantitative modular modeling approach reveals the effects of different A20 feedback implementations for the NF-κB signaling dynamics

J. Mothes
I. Ipenberg
S.Ç. Arslan
U. Benary
C. Scheidereit
J. Wolf

01. Juni 2020 in J Pathol

Deficiency in IκBα in the intestinal epithelium leads to spontaneous inflammation and mediates apoptosis in the gut

N. Mikuda
R. Schmidt-Ullrich
E. Kärgel
L. Golusda
J. Wolf
U.E. Höpken
C. Scheidereit
A.A. Kühl
M. Kolesnichenko

09. April 2020 in JCI Insight

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

P. Dembny
A.G. Newman
M. Singh
M. Hinz
M. Szczepek
C. Krüger
R. Adalbert
O. Dzaye
T. Trimbuch
T. Wallach
G. Kleinau
K. Derkow
B.C. Richard
C. Schipke
C. Scheidereit
H. Stachelscheid
D. Golenbock
O. Peters
M. Coleman
F.L. Heppner
P. Scheerer
V. Tarabykin
K. Ruprecht
Z. Izsvák
J. Mayer
S. Lehnardt

01. Februar 2020 in J Cachexia Sarcopenia Muscle

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors

A. Hahn
M. Kny
C. Pablo-Tortola
M. Todiras
M. Willenbrock
S. Schmidt
K. Schmoeckel
I. Jorde
M. Nowak
E. Jarosch
T. Sommer
B.M. Bröker
S.B. Felix
C. Scheidereit
S. Weber-Carstens
C. Butter
F.C. Luft
J. Fielitz

24. September 2019 in Cell Rep

Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells

N.T. Tran
T. Sommermann
R. Graf
J. Trombke
J. Pempe
K. Petsch
R. Kühn
K. Rajewsky
V.T. Chu

01. Juli 2019 in Front Genet

Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells

T.T.H. Le
N.T. Tran
T.M.L. Dao
D.D. Nguyen
H.D. Do
T.L. Ha
R. Kühn
T.L. Nguyen
K. Rajewsky
V.T. Chu

30. April 2019 in Front Genet

Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors

N.T. Tran
S. Bashir
X. Li
J. Rossius
V.T. Chu
K. Rajewsky
R. Kühn

28. März 2019 in Blood

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma

L. von Hoff
E. Kärgel
V. Franke
E. McShane
K.W. Schulz-Beiss
G. Patone
N. Schleussner
M. Kolesnichenko
N. Hübner
O. Daumke
M. Selbach
A. Akalin
S. Mathas
C. Scheidereit