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April 2013 / J Am Soc Nephrol Small-molecule screening identifies modulators of aquaporin-2 trafficking J. Bogum D. Faust K. Zühlke J. Eichhorst M.C. Moutty J. Furkert A. Eldahshan M. Neuenschwander J.P. von Kries B. Wiesner C. Trimpert P.M. Deen G. Valenti W. Rosenthal E. Klussmann 12. Mai 2011 / J Med Chem Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4) J.P. Day B. Lindsay T. Riddell Z. Jiang R.W. Allcock A. Abraham S. Sookup F. Christian J. Bogum E.K. Martin R.L. Rae D. Anthony G.M. Rosair D.M. Houslay E. Huston G.S. Baillie E. Klussmann M.D. Houslay D.R. Adams 01. Dezember 2010 / Biophys J Routes of epithelial water flow: aquaporins versus cotransporters R. Mollajew F. Zocher A. Horner B. Wiesner E. Klussmann P. Pohl 15. Mai 2010 / Biochem J Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK X. Li S. Vadrevu A. Dunlop J. Day N. Advant J. Troeger E. Klussmann E. Jaffrey R.T. Hay D.R. Adams M.D. Houslay G.S. Baillie 24. April 2009 / J Biol Chem MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization D. Meng M.J. Lynch E. Huston M. Beyermann J. Eichhorst D.R. Adams E. Klussmann M.D. Houslay G.S. Baillie 01. Dezember 2007 / Cell Signal 1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1 K.J. Smith G.S. Baillie E.I. Hyde X. Li T.M. Houslay A. McCahill A.J. Dunlop G.B. Bolger E. Klussmann D.R. Adams M.D. Houslay 29. August 2007 / J Neurosci Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels H. Murdoch S. Mackie D.M. Collins E.V. Hill G.B. Bolger E. Klussmann D.J. Porteous J.K. Millar M.D. Houslay 18. Juni 2007 / J Cell Biol p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway B.D. Sachs G.S. Baillie J.R. McCall M.A. Passino C. Schachtrup D.A. Wallace A.J. Dunlop K.F. MacKenzie E. Klussmann M.J. Lynch S.L. Sikorski T. Nuriel I. Tsigelny J. Zhang M.D. Houslay M.V. Chao K. Akassoglou 15. Mai 2007 / Biochem J Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays G.S. Baillie D.R. Adams N. Bhari T.M. Houslay S. Vadrevu D. Meng X. Li A. Dunlop G. Milligan G.B. Bolger E. Klussmann M.D. Houslay 15. August 2006 / Biochem J Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5 G.B. Bolger G.S. Baillie X. Li M.J. Lynch P. Herzyk A. Mohamed L.H. Mitchell A. McCahill C. Hundsrucker E. Klussmann D.R. Adams M.D. Houslay Seitennummerierung Aktuelle Seite 1 Seite 2 Seite 3 Seite 4 … Nächste Seite Next › Letzte Seite Last »
01. April 2013 / J Am Soc Nephrol Small-molecule screening identifies modulators of aquaporin-2 trafficking J. Bogum D. Faust K. Zühlke J. Eichhorst M.C. Moutty J. Furkert A. Eldahshan M. Neuenschwander J.P. von Kries B. Wiesner C. Trimpert P.M. Deen G. Valenti W. Rosenthal E. Klussmann
12. Mai 2011 / J Med Chem Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4) J.P. Day B. Lindsay T. Riddell Z. Jiang R.W. Allcock A. Abraham S. Sookup F. Christian J. Bogum E.K. Martin R.L. Rae D. Anthony G.M. Rosair D.M. Houslay E. Huston G.S. Baillie E. Klussmann M.D. Houslay D.R. Adams
01. Dezember 2010 / Biophys J Routes of epithelial water flow: aquaporins versus cotransporters R. Mollajew F. Zocher A. Horner B. Wiesner E. Klussmann P. Pohl
15. Mai 2010 / Biochem J Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK X. Li S. Vadrevu A. Dunlop J. Day N. Advant J. Troeger E. Klussmann E. Jaffrey R.T. Hay D.R. Adams M.D. Houslay G.S. Baillie
24. April 2009 / J Biol Chem MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization D. Meng M.J. Lynch E. Huston M. Beyermann J. Eichhorst D.R. Adams E. Klussmann M.D. Houslay G.S. Baillie
01. Dezember 2007 / Cell Signal 1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1 K.J. Smith G.S. Baillie E.I. Hyde X. Li T.M. Houslay A. McCahill A.J. Dunlop G.B. Bolger E. Klussmann D.R. Adams M.D. Houslay
29. August 2007 / J Neurosci Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels H. Murdoch S. Mackie D.M. Collins E.V. Hill G.B. Bolger E. Klussmann D.J. Porteous J.K. Millar M.D. Houslay
18. Juni 2007 / J Cell Biol p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway B.D. Sachs G.S. Baillie J.R. McCall M.A. Passino C. Schachtrup D.A. Wallace A.J. Dunlop K.F. MacKenzie E. Klussmann M.J. Lynch S.L. Sikorski T. Nuriel I. Tsigelny J. Zhang M.D. Houslay M.V. Chao K. Akassoglou
15. Mai 2007 / Biochem J Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays G.S. Baillie D.R. Adams N. Bhari T.M. Houslay S. Vadrevu D. Meng X. Li A. Dunlop G. Milligan G.B. Bolger E. Klussmann M.D. Houslay
15. August 2006 / Biochem J Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5 G.B. Bolger G.S. Baillie X. Li M.J. Lynch P. Herzyk A. Mohamed L.H. Mitchell A. McCahill C. Hundsrucker E. Klussmann D.R. Adams M.D. Houslay